Nos1 (nitric oxide synthase 1, neuronal) - Rat Genome Database

Send us a Message

Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Nos1 (nitric oxide synthase 1, neuronal) Mus musculus
Symbol: Nos1
Name: nitric oxide synthase 1, neuronal
RGD ID: 10991
Description: Enables nitric-oxide synthase activity. Involved in several processes, including nitric oxide biosynthetic process; positive regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process; and positive regulation of nitrogen compound metabolic process. Acts upstream of or within several processes, including peptidyl-cysteine S-nitrosylation; positive regulation of transcription by RNA polymerase II; and regulation of metal ion transport. Located in several cellular components, including T-tubule; Z disc; and sarcoplasmic reticulum membrane. Is active in calyx of Held. Colocalizes with caveola. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Used to study achalasia and hypertrophic pyloric stenosis. Human ortholog(s) of this gene implicated in Alzheimer's disease; Parkinson's disease; asthma; cystic fibrosis; and hypertrophic pyloric stenosis. Orthologous to human NOS1 (nitric oxide synthase 1).
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2310005C01Rik; b; bNOS; constitutive NOS; N-NOS; NC-NOS; neuronal nitric oxide synthase; neuronal NOS; nitric oxide synthase, brain; nNOS; NO; NOS; NOS type I; Nos-1; NOS-I; peptidyl-cysteine S-nitrosylase NOS1; RIKEN cDNA 2310005C01 gene
RGD Orthologs
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm395118,004,904 - 118,096,905 (+)NCBIGRCm39mm39
GRCm39 Ensembl5117,919,097 - 118,096,905 (+)Ensembl
GRCm385117,866,839 - 117,958,840 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5117,781,032 - 117,958,840 (+)EnsemblGRCm38mm10GRCm38
MGSCv375118,317,128 - 118,403,822 (+)NCBIGRCm37mm9NCBIm37
MGSCv365118,128,149 - 118,214,843 (+)NCBImm8
Celera5114,958,747 - 115,046,830 (+)NCBICelera
Cytogenetic Map5FNCBI
cM Map557.29NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations     Click to see Annotation Detail View
achalasia  (IEA)
acute kidney failure  (ISO)
acute necrotizing pancreatitis  (ISO)
alcoholic cardiomyopathy  (ISO)
Alzheimer's disease  (ISO)
amphetamine abuse  (ISO)
arteriosclerosis  (IAGP)
asthma  (ISO)
brain ischemia  (ISO)
Bronchial Hyperreactivity  (IEP)
Carbon Monoxide Poisoning  (IMP)
Cardiomegaly  (ISO)
cardiomyopathy  (ISO)
cerebellar disease  (ISO)
chronic obstructive pulmonary disease  (ISO)
congestive heart failure  (ISO)
cystic fibrosis  (ISO)
Dehydration  (ISO)
Diabetic Nephropathies  (ISO)
diabetic retinopathy  (ISO)
disease of mental health  (ISO)
Duchenne muscular dystrophy  (ISO)
End Stage Liver Disease  (ISO)
end stage renal disease  (ISO)
Experimental Diabetes Mellitus  (ISO)
fetal alcohol spectrum disorder  (ISO)
Fetal Growth Retardation  (ISO)
Fetal Hypoxia  (ISO)
Fever  (ISO)
Heat Stroke  (ISO)
hepatic encephalopathy  (ISO)
Human Influenza  (IEP)
Hyperalgesia  (ISO)
hypertension  (ISO)
hypertrophic pyloric stenosis  (IEA)
Hypoxia  (ISO)
impotence  (ISO)
intestinal perforation  (ISO)
intracranial aneurysm  (IMP)
major depressive disorder  (ISO)
Memory Disorders  (ISO)
mental depression  (ISO)
morphine dependence  (ISO)
motor neuron disease  (ISO)
nephrotic syndrome  (ISO)
Nerve Degeneration  (ISO)
nervous system disease  (ISO)
Nervous System Trauma  (ISO)
Neuralgia  (ISO)
Neurobehavioral Manifestations  (ISO)
obesity  (ISO)
Parkinson's disease  (ISO)
Parkinsonism  (ISO)
portal hypertension  (ISO)
Prehypertension  (ISO)
Pyloric Stenosis, Infantile Hypertrophic 1  (ISO)
Radiation Injuries, Experimental  (ISO)
renovascular hypertension  (ISO)
Reperfusion Injury  (ISO)
retinopathy of prematurity  (ISO)
Right Ventricular Hypertrophy  (ISO)
schizophrenia  (ISO)
Sepsis  (ISO)
Spinal Cord Injuries  (ISO)
status epilepticus  (ISO)
Stroke  (ISO)
temporal lobe epilepsy  (ISO)
transient cerebral ischemia  (ISO)
type 1 diabetes mellitus  (ISO)
type 2 diabetes mellitus  (ISO)
urethral obstruction  (ISO)
Urination Disorders  (ISO)
Ventricular Remodeling  (ISO)
visual epilepsy  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-pilocarpine  (ISO)
(3,4-dihydroxyphenyl)acetic acid  (EXP)
(S)-amphetamine  (EXP)
(S)-colchicine  (ISO)
1,2-dimethylhydrazine  (EXP,ISO)
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine  (EXP)
17beta-estradiol  (ISO)
17beta-estradiol 3-benzoate  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP)
2,4,6-trinitrotoluene  (ISO)
2-(4-iodo-2,5-dimethoxyphenyl)-1-methylethylamine  (ISO)
3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine  (ISO)
3,3',5,5'-tetrabromobisphenol A  (EXP)
3,4-methylenedioxymethamphetamine  (EXP,ISO)
3-\{1-[3-(dimethylamino)propyl]-1H-indol-3-yl\}-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione  (ISO)
4-hydroxy-TEMPO  (ISO)
5,5-dimethyl-1-pyrroline N-oxide  (ISO)
6-propyl-2-thiouracil  (ISO)
8'-apo-beta,psi-caroten-8'-al  (ISO)
acetamide  (ISO)
acrylamide  (ISO)
ADP-D-ribose  (EXP)
Aflatoxin B2 alpha  (ISO)
aldehydo-D-glucose  (ISO)
alloxan  (EXP)
aluminium sulfate (anhydrous)  (ISO)
aminoguanidine  (ISO)
ammonium chloride  (EXP)
Aroclor 1254  (ISO)
benzo[a]pyrene  (EXP,ISO)
beta-carotene  (ISO)
betulinic acid  (EXP,ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bortezomib  (EXP,ISO)
Brodifacoum  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
calcium atom  (ISO)
calcium dichloride  (ISO)
calcium(0)  (ISO)
Candesartan cilexetil  (ISO)
cantharidin  (ISO)
capsaicin  (ISO)
chaetocin  (ISO)
chlorpyrifos  (ISO)
cisplatin  (ISO)
cobalt dichloride  (ISO)
cocaine  (EXP,ISO)
copper atom  (ISO)
copper(0)  (ISO)
curcumin  (EXP,ISO)
D-glucose  (ISO)
decabromodiphenyl ether  (EXP)
Decursin  (EXP)
dexamethasone  (EXP,ISO)
dibutylstannane  (ISO)
dichlorine  (ISO)
dichloroacetic acid  (EXP)
dimemorfan  (ISO)
diminazene diaceturate  (ISO)
dioxygen  (ISO)
disodium selenite  (ISO)
dizocilpine maleate  (EXP)
dobutamine  (EXP)
dopamine  (EXP)
dorsomorphin  (ISO)
edaravone  (ISO)
endosulfan  (ISO)
enoxacin  (EXP)
entinostat  (ISO)
enzyme inhibitor  (ISO)
ethanol  (EXP,ISO)
ethylene glycol bis(2-aminoethyl)tetraacetic acid  (ISO)
fenbufen  (EXP)
flutamide  (ISO)
folic acid  (EXP)
formaldehyde  (ISO)
gentamycin  (EXP)
glucose  (ISO)
GW 4064  (EXP)
hexachlorobenzene  (ISO)
hexacosan-1-ol  (ISO)
homovanillic acid  (EXP)
hydralazine  (ISO)
hydrogen peroxide  (ISO)
ibuprofen  (ISO)
icariin  (ISO)
ifosfamide  (ISO)
indometacin  (EXP)
isoprenaline  (ISO)
kainic acid  (ISO)
KT 5720  (ISO)
lead diacetate  (EXP,ISO)
lead(II) chloride  (ISO)
leflunomide  (ISO)
linsidomine  (ISO)
lipopolysaccharide  (EXP,ISO)
lithium atom  (ISO)
lithium chloride  (ISO)
lithium hydride  (ISO)
losartan  (ISO)
lycopene  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (EXP)
manganese(II) sulfate  (ISO)
mastoparan  (ISO)
Mazindol  (EXP)
melatonin  (ISO)
melittin  (ISO)
mephedrone  (ISO)
mercury dichloride  (ISO)
metformin  (EXP)
methamphetamine  (EXP)
methoctramine tetrahydrochloride  (ISO)
metoprolol  (ISO)
mevinphos  (ISO)
milrinone  (EXP)
morin  (ISO)
morphine  (EXP,ISO)
N,N-diethyl-m-toluamide  (ISO)
N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide  (ISO)
N-ethyl-N-nitrosourea  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
naloxone  (EXP)
Neferine  (ISO)
nickel atom  (ISO)
nitric oxide  (EXP,ISO)
nitroglycerin  (ISO)
nitroprusside  (ISO)
O-acetyl-L-carnitine  (ISO)
ouabain  (ISO)
oxidopamine  (ISO)
ozone  (ISO)
p-menthan-3-ol  (ISO)
palytoxin  (ISO)
paracetamol  (ISO)
paraquat  (EXP)
perfluorooctane-1-sulfonic acid  (ISO)
permethrin  (ISO)
phenol  (ISO)
phenylmercury acetate  (ISO)
phorbol 13-acetate 12-myristate  (EXP)
progesterone  (EXP,ISO)
propanal  (ISO)
puerarin  (EXP)
quercetin  (EXP,ISO)
ramipril  (ISO)
reactive nitrogen species  (ISO)
reactive oxygen species  (ISO)
reserpine  (ISO)
resveratrol  (EXP,ISO)
rofecoxib  (ISO)
S-methyl-L-thiocitrulline  (EXP,ISO)
SB 431542  (ISO)
selenic acid  (ISO)
selenomethionine  (ISO)
serpentine asbestos  (ISO)
sildenafil citrate  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sirtinol  (ISO)
sodium arsenite  (ISO)
sodium atom  (ISO)
sodium chloride  (ISO)
sodium sulfite  (ISO)
streptozocin  (ISO)
sumatriptan  (ISO)
tacrine  (ISO)
tacrolimus hydrate  (ISO)
tamoxifen  (ISO)
testosterone  (ISO)
tetrachloromethane  (ISO)
tributylstannane  (ISO)
triclosan  (EXP)
triphenylstannane  (ISO)
triptonide  (EXP)
Tropicamide  (ISO)
U-73122  (ISO)
udenafil  (ISO)
valproic acid  (ISO)
valsartan  (ISO)
vincristine  (EXP)
zileuton  (EXP)
zinc protoporphyrin  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
aging  (ISO)
arginine catabolic process  (IBA,ISO)
behavioral response to cocaine  (ISO)
brain development  (ISO)
cellular response to epinephrine stimulus  (ISO)
cellular response to growth factor stimulus  (IMP)
cellular response to mechanical stimulus  (ISO)
establishment of protein localization  (ISO)
female pregnancy  (ISO)
multicellular organismal response to stress  (ISO)
muscle contraction  (IBA)
negative regulation of apoptotic process  (ISO)
negative regulation of blood pressure  (IBA,ISO)
negative regulation of calcium ion transport  (IMP)
negative regulation of cell population proliferation  (ISO)
negative regulation of cytosolic calcium ion concentration  (ISO)
negative regulation of heart contraction  (ISO)
negative regulation of hepatic stellate cell contraction  (ISO)
negative regulation of hydrolase activity  (IMP)
negative regulation of insulin secretion  (ISO)
negative regulation of iron ion transmembrane transport  (ISO)
negative regulation of neuron apoptotic process  (ISO)
negative regulation of peptidyl-serine phosphorylation  (ISO)
negative regulation of potassium ion transport  (IMP)
negative regulation of serotonin uptake  (IDA)
negative regulation of vasoconstriction  (ISO)
nitric oxide biosynthetic process  (IBA,IDA,ISO)
nitric oxide mediated signal transduction  (IBA,ISO)
peptidyl-cysteine S-nitrosylation  (IDA,ISO)
positive regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process  (IMP)
positive regulation of guanylate cyclase activity  (IBA)
positive regulation of histone acetylation  (IMP)
positive regulation of long-term synaptic potentiation  (ISO)
positive regulation of neuron death  (ISO)
positive regulation of peptidyl-serine phosphorylation  (ISO)
positive regulation of sodium ion transmembrane transport  (ISO)
positive regulation of the force of heart contraction  (IMP)
positive regulation of transcription by RNA polymerase II  (IMP)
positive regulation of transcription, DNA-templated  (IMP)
regulation of heart contraction  (ISO)
regulation of neurogenesis  (IDA)
regulation of sensory perception of pain  (ISO)
regulation of sodium ion transport  (IMP)
response to activity  (ISO)
response to estrogen  (ISO)
response to ethanol  (ISO)
response to heat  (ISO)
response to hormone  (IBA)
response to hypoxia  (ISO)
response to lead ion  (ISO)
response to lipopolysaccharide  (IBA,ISO)
response to nicotine  (ISO)
response to nitric oxide  (ISO)
response to nutrient levels  (ISO)
response to organic cyclic compound  (ISO)
response to organonitrogen compound  (ISO)
response to peptide hormone  (ISO)
response to vitamin E  (ISO)
retrograde trans-synaptic signaling by nitric oxide  (IBA,IMP)
striated muscle contraction  (IMP)
synaptic signaling by nitric oxide  (IDA,IMP)
vasodilation  (ISO)
xenobiotic catabolic process  (IMP)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal angiogenesis  (IAGP)
abnormal behavioral response to addictive substance  (IAGP)
abnormal blood-brain barrier function  (IAGP)
abnormal bone mineralization  (IAGP)
abnormal bone structure  (IAGP)
abnormal brain morphology  (IAGP)
abnormal brain wave pattern  (IAGP)
abnormal breathing pattern  (IAGP)
abnormal carbon dioxide production  (IAGP)
abnormal cardiac muscle relaxation  (IAGP)
abnormal cardiovascular system morphology  (IAGP)
abnormal cardiovascular system physiology  (IAGP)
abnormal cerebral blood flow rate  (IAGP)
abnormal circulating glucose level  (IAGP)
abnormal circulating pyruvate kinase level  (IAGP)
abnormal coronary artery morphology  (IAGP)
abnormal dendrite morphology  (IAGP)
abnormal digestion  (IAGP)
abnormal gastroesophageal sphincter physiology  (IAGP)
abnormal glomerular capillary thrombosis  (IAGP)
abnormal heart rate  (IAGP)
abnormal hepatocyte morphology  (IAGP)
abnormal hypothalamus secretion  (IAGP)
abnormal kidney physiology  (IAGP)
abnormal leukocyte adhesion  (IAGP)
abnormal liquid preference  (IAGP)
abnormal liver morphology  (IAGP)
abnormal long term potentiation  (IAGP)
abnormal maternal behavior  (IAGP)
abnormal mating frequency  (IAGP)
abnormal mitochondrial physiology  (IAGP)
abnormal motor neuron morphology  (IAGP)
abnormal muscle physiology  (IAGP)
abnormal muscle relaxation  (IAGP)
abnormal nervous system physiology  (IAGP)
abnormal neuron differentiation  (IAGP)
abnormal neutrophil physiology  (IAGP)
abnormal nitric oxide homeostasis  (IAGP)
abnormal osteoclast differentiation  (IAGP)
abnormal osteoclast physiology  (IAGP)
abnormal ovulation  (IAGP)
abnormal oxygen consumption  (IAGP)
abnormal peripheral nervous system regeneration  (IAGP)
abnormal physiological response to xenobiotic  (IAGP)
abnormal pulmonary respiratory rate response  (IAGP)
abnormal renal glomerulus morphology  (IAGP)
abnormal renal reabsorption  (IAGP)
abnormal renal tubule morphology  (IAGP)
abnormal renal water reabsorption  (IAGP)
abnormal response of heart to induced stress  (IAGP)
abnormal seizure response to inducing agent  (IAGP)
abnormal sensory neuron innervation pattern  (IAGP)
abnormal serotonin level  (IAGP)
abnormal skeleton development  (IAGP)
abnormal skeleton physiology  (IAGP)
abnormal sleep pattern  (IAGP)
abnormal spatial learning  (IAGP)
abnormal stomach wall morphology  (IAGP)
abnormal trabecular bone morphology  (IAGP)
abnormal vascular endothelial cell physiology  (IAGP)
abnormal vascular wound healing  (IAGP)
absent long term depression  (IAGP)
arteriosclerosis  (IAGP)
cardiac interstitial fibrosis  (IAGP)
congestive heart failure  (IAGP)
decreased adiponectin level  (IAGP)
decreased aggression towards males  (IAGP)
decreased body weight  (IAGP)
decreased cardiac muscle contractility  (IAGP)
decreased cerebral infarct size  (IAGP)
decreased circulating follicle stimulating hormone level  (IAGP)
decreased circulating thyroxine level  (IAGP)
decreased coronary flow rate  (IAGP)
decreased corpora lutea number  (IAGP)
decreased heart rate  (IAGP)
decreased heart weight  (IAGP)
decreased inflammatory response  (IAGP)
decreased left ventricle diastolic pressure  (IAGP)
decreased mean systemic arterial blood pressure  (IAGP)
decreased ovary weight  (IAGP)
decreased oxygen consumption  (IAGP)
decreased sensitivity to induced morbidity/mortality  (IAGP)
decreased skeletal muscle weight  (IAGP)
decreased survivor rate  (IAGP)
decreased susceptibility to induced choroidal neovascularization  (IAGP)
decreased susceptibility to injury  (IAGP)
decreased susceptibility to ischemic brain injury  (IAGP)
decreased susceptibility to neuronal excitotoxicity  (IAGP)
decreased synaptic glutamate release  (IAGP)
decreased testis weight  (IAGP)
decreased urine osmolality  (IAGP)
decreased urine sodium level  (IAGP)
dehydration  (IAGP)
delayed estrous cycle  (IAGP)
dystrophic muscle  (IAGP)
enhanced behavioral response to addictive substance  (IAGP)
enhanced coordination  (IAGP)
enhanced leukocyte tethering or rolling  (IAGP)
enlarged duodenum  (IAGP)
enlarged esophagus  (IAGP)
enlarged stomach  (IAGP)
gastric hypertrophy  (IAGP)
glomerulosclerosis  (IAGP)
heart left ventricle hypertrophy  (IAGP)
hypertension  (IAGP)
hypoactivity  (IAGP)
impaired balance  (IAGP)
impaired gastric peristalsis  (IAGP)
impaired skeletal muscle contractility  (IAGP)
increased aggression towards females  (IAGP)
increased aggression towards males  (IAGP)
increased alcohol consumption  (IAGP)
increased anxiety-related response  (IAGP)
increased blood osmolality  (IAGP)
increased blood urea nitrogen level  (IAGP)
increased body weight  (IAGP)
increased bone mineral content  (IAGP)
increased bone mineral density  (IAGP)
increased cardiac muscle contractility  (IAGP)
increased circulating alkaline phosphatase level  (IAGP)
increased circulating corticosterone level  (IAGP)
increased circulating creatinine level  (IAGP)
increased circulating glucose level  (IAGP)
increased circulating insulin level  (IAGP)
increased circulating LDL cholesterol level  (IAGP)
increased circulating leptin level  (IAGP)
increased circulating luteinizing hormone level  (IAGP)
increased circulating triglyceride level  (IAGP)
increased coping response  (IAGP)
increased food intake  (IAGP)
increased grooming behavior  (IAGP)
increased heart rate  (IAGP)
increased osteoclast cell number  (IAGP)
increased oxygen consumption  (IAGP)
increased physiological sensitivity to xenobiotic  (IAGP)
increased prostaglandin level  (IAGP)
increased pulmonary respiratory rate  (IAGP)
increased pulmonary ventilation  (IAGP)
increased renal tubule apoptosis  (IAGP)
increased systemic arterial blood pressure  (IAGP)
increased systemic arterial systolic blood pressure  (IAGP)
increased tidal volume  (IAGP)
increased total body fat amount  (IAGP)
increased trabecular bone thickness  (IAGP)
increased trabecular bone volume  (IAGP)
increased urine bicarbonate level  (IAGP)
increased urine pH  (IAGP)
increased ventricle muscle contractility  (IAGP)
increased white adipose tissue amount  (IAGP)
insulin resistance  (IAGP)
liver vascular congestion  (IAGP)
male infertility  (IAGP)
maternal effect  (IAGP)
metabolic acidosis  (IAGP)
muscle fatigue  (IAGP)
no abnormal phenotype detected  (IEA)
perivascular fibrosis  (IAGP)
polydipsia  (IAGP)
polyuria  (IAGP)
premature death  (IAGP)
prenatal lethality, incomplete penetrance  (IAGP)
pulmonary vascular congestion  (IAGP)
pyloric sphincter hypertrophy  (IAGP)
pyloric stenosis  (IAGP)
reduced female fertility  (IAGP)
reduced fertility  (IAGP)
reduced long term potentiation  (IAGP)
renal tubular necrosis  (IAGP)
stomach smooth muscle circular layer hypertrophy  (IAGP)
thick ventricular wall  (IAGP)
visceral vascular congestion  (IAGP)

References - curated
1. Amour J, etal., Anesthesiology. 2007 Sep;107(3):452-460.
2. Aoki T, etal., Lab Invest. 2011 Apr;91(4):619-26. Epub 2011 Feb 14.
3. Asakura J, etal., Nephron Exp Nephrol. 2012;122(3-4):83-94. doi: 10.1159/000348661. Epub 2013 Mar 29.
4. Barreiro E, etal., Am J Respir Cell Mol Biol. 2003 Dec;29(6):771-8. Epub 2003 Jun 19.
5. Baxter RG, etal., Acta Neuropathol. 2002 Oct;104(4):391-7. Epub 2002 Jun 26.
6. Bendall JK, etal., Circulation. 2004 Oct 19;110(16):2368-75. Epub 2004 Oct 4.
7. Brindicci C, etal., Am J Respir Crit Care Med. 2010 Jan 1;181(1):21-30. Epub 2009 Sep 24.
8. Cheng BC, etal., Neuropharmacology. 2007 Feb;52(2):297-305. Epub 2006 Sep 6.
9. Davidova A, etal., Cell Mol Neurobiol. 2009 Sep;29(6-7):879-86. Epub 2009 Mar 17.
10. Ding YX, etal., Zhongguo Zhen Jiu. 2013 Jun;33(6):533-7.
11. Dotsch J, etal., Eur Arch Otorhinolaryngol. 2002 Apr;259(4):222-6.
12. Fatemi SH, etal., Synapse. 1998 May;29(1):84-8.
13. Ferrari MF and Fior-Chadi DR, J Hypertens. 2005 Sep;23(9):1683-90.
14. Galimberti D, etal., Neurobiol Aging. 2008 Sep;29(9):1359-65. doi: 10.1016/j.neurobiolaging.2007.03.003. Epub 2007 Apr 6.
15. Gangula PR, etal., Am J Physiol Gastrointest Liver Physiol. 2007 Mar;292(3):G725-33.
16. Gao PS, etal., Biochem Biophys Res Commun. 2000 Jan 27;267(3):761-3.
17. Gao SF, etal., Psychoneuroendocrinology. 2014 Sep;47:136-40. doi: 10.1016/j.psyneuen.2014.05.009. Epub 2014 May 22.
18. Gatto EM, etal., Nitric Oxide. 2000 Oct;4(5):534-9.
19. Gossrau R, Acta Histochem. 1998 Feb;100(1):99-112. doi: 10.1016/S0065-1281(98)80009-3.
20. Grasemann H, etal., Biochem Biophys Res Commun. 2000 Jun 7;272(2):391-4.
21. Grasemann H, etal., Nitric Oxide. 2002 Mar;6(2):236-41.
22. Hauser W, etal., Brain Res Mol Brain Res. 2005 Aug 18;138(2):198-204.
23. Huang CF, etal., Eur J Pharmacol. 2013 Jan 15;699(1-3):233-40. doi: 10.1016/j.ejphar.2012.11.034. Epub 2012 Nov 28.
24. Hugyecz M, etal., Brain Res. 2011 Aug 2;1404:31-8. Epub 2011 Jun 12.
25. Jeong HH, etal., Urology. 2013 May;81(5):1108.e7-14. doi: 10.1016/j.urology.2013.01.022. Epub 2013 Mar 22.
26. Jiang J, etal., Br J Pharmacol. 2013 Aug 2. doi: 10.1111/bph.12326.
27. Jiang MH and Hada J, Eur J Pharmacol. 2007 Jul 12;567(1-2):83-8. Epub 2007 Mar 24.
28. Kim SJ, etal., Korean J Ophthalmol. 2012 Dec;26(6):455-61. doi: 10.3341/kjo.2012.26.6.455. Epub 2012 Nov 12.
29. Kim SO, etal., Can Urol Assoc J. 2013 May-Jun;7(5-6):E268-74. doi: 10.5489/cuaj.993.
30. Klawitter V, etal., Exp Brain Res. 2007 Jun;180(1):139-52. Epub 2007 Feb 20.
31. Komers R, etal., Am J Physiol Renal Physiol. 2000 Sep;279(3):F573-83. doi: 10.1152/ajprenal.2000.279.3.F573.
32. Kuhlencordt PJ, etal., Arterioscler Thromb Vasc Biol. 2006 Jul;26(7):1539-44. Epub 2006 Apr 20.
33. Li D, etal., Hypertension. 2013 Jan;61(1):202-7. doi: 10.1161/HYPERTENSIONAHA.111.00105. Epub 2012 Nov 19.
34. Li Z, etal., Kidney Int. 2005 Dec;68(6):2766-72.
35. Lian T and An SC, Sheng Li Xue Bao. 2010 Jun 25;62(3):237-46.
36. Liu J, etal., Int J Mol Sci. 2013 May 21;14(5):10661-73. doi: 10.3390/ijms140510661.
37. Liu K, etal., Brain Inj. 2009 May;23(5):450-8.
38. Liu ZW, etal., Neurochem Res. 2007 Jun 5;.
39. Lo HS, etal., J Neurol Sci 2002 Feb 15;194(1):11-3.
40. Loyer X, etal., Endocrinology. 2007 Aug 2;.
41. Lüth HJ, etal., Brain Res. 2002 Oct 25;953(1-2):135-43.
42. Malykhina AP, etal., Am J Physiol Regul Integr Comp Physiol. 2013 May 15;304(10):R837-45. doi: 10.1152/ajpregu.00558.2012. Epub 2013 Mar 27.
43. MGD and Homologene mouse data transfer
44. MGD data from the GO Consortium
46. Mulvey C, etal., Eur J Cell Biol. 2005 Nov;84(11):867-83.
47. Ni Z and Vaziri ND, Biochim Biophys Acta. 2003 Jul 14;1638(2):129-37.
48. Ninkovic M, etal., Acta Physiol Hung. 2006 Dec;93(4):315-23.
49. North ML, etal., Am J Physiol Lung Cell Mol Physiol. 2009 Jun;296(6):L911-20. Epub 2009 Mar 13.
50. OMIM Disease Annotation Pipeline
51. Osuka K, etal., Neurochem Int. 2013 Jun 24;63(4):269-274. doi: 10.1016/j.neuint.2013.06.011.
52. Palsson E, etal., Psychopharmacology (Berl). 2010 Dec;212(4):643-51. Epub 2010 Aug 28.
53. Pipeline to import KEGG annotations from KEGG into RGD
54. Pipeline to import SMPDB annotations from SMPDB into RGD
55. Qin JY, etal., Zhongguo Zhong Xi Yi Jie He Za Zhi. 2012 Sep;32(9):1280-4.
56. Reif A, etal., J Alzheimers Dis. 2011;23(2):327-33. doi: 10.3233/JAD-2010-101491.
57. RGD automated import pipeline
58. RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
59. RGD automated import pipeline for gene-chemical interactions
60. Rossi NF, etal., Exp Physiol. 2010 Aug;95(8):845-57. Epub 2010 May 21.
61. Shao C, etal., J Hum Genet. 2004;49(3):115-22. Epub 2004 Feb 7.
62. Sharma HS Ann N Y Acad Sci. 2010 Jun;1199:175-85.
63. Sharma NM, etal., Am J Physiol Heart Circ Physiol. 2013 Jul 5.
64. Simic G, etal., Exp Neurol. 2000 Sep;165(1):12-26. doi: 10.1006/exnr.2000.7448.
65. Skarzinski G, etal., Placenta. 2009 Oct;30(10):898-906. Epub 2009 Aug 25.
66. Suarez I, etal., Metab Brain Dis. 2009 Sep;24(3):395-408.
67. Suarez I, etal., Neuropathol Appl Neurobiol. 2006 Dec;32(6):594-604.
68. Szabo AJ, etal., Kidney Int. 2003 Nov;64(5):1765-71. doi: 10.1046/j.1523-1755.2003.00260.x.
69. Tain YL, etal., Am J Physiol Renal Physiol. 2007 May;292(5):F1404-10. Epub 2007 Jan 2.
70. Tandai-Hiruma M, etal., J Hypertens. 2005 Apr;23(4):825-34.
71. Texereau J, etal., Thorax. 2004 Feb;59(2):156-8.
72. Theilig F, etal., Am J Physiol Renal Physiol. 2006 Nov;291(5):F987-94. Epub 2006 Jun 20.
73. Thom SR, etal., Toxicol Appl Pharmacol. 2004 Feb 1;194(3):280-95. doi: 10.1016/j.taap.2003.09.017.
74. Umar S, etal., Pathol Res Pract. 2007;203(12):863-72. Epub 2007 Oct 29.
75. Wang J, etal., Mol Cell Biochem. 2007 Jul 3;.
76. Wang TN, etal., Pediatr Allergy Immunol. 2010 Nov;21(7):1064-71. doi: 10.1111/j.1399-3038.2009.00981.x.
77. Wyneken U, etal., Neuroscience. 2001;102(1):65-74.
78. Yan LP, etal., Zhen Ci Yan Jiu. 2012 Oct;37(5):345-50.
79. Yao ST, etal., J Comp Neurol. 2005 Sep 19;490(2):180-93. doi: 10.1002/cne.20662.
80. Yono M, etal., Life Sci. 2007 Jun 27;81(3):218-22. Epub 2007 May 21.
81. Yu Q, etal., J Clin Invest. 2000 Mar;105(6):741-8. doi: 10.1172/JCI7997.
82. Yuan AH, etal., Nan Fang Yi Ke Da Xue Xue Bao. 2007 Apr;27(4):454-7.
83. Zhou H, etal., PLoS One. 2012;7(12):e52163. doi: 10.1371/journal.pone.0052163. Epub 2012 Dec 26.
Additional References at PubMed
PMID:1372907   PMID:7477374   PMID:7478547   PMID:7505721   PMID:7508208   PMID:7518067   PMID:7518615   PMID:7522345   PMID:7522969   PMID:7529143   PMID:7536496   PMID:7541381  
PMID:7545544   PMID:7564879   PMID:7673702   PMID:7686743   PMID:8567692   PMID:8612510   PMID:8625413   PMID:8626668   PMID:8657306   PMID:8661069   PMID:8667023   PMID:8780207  
PMID:8784782   PMID:8786143   PMID:8799168   PMID:8806629   PMID:8848263   PMID:8889548   PMID:8899742   PMID:8914934   PMID:8929451   PMID:8978606   PMID:9001139   PMID:9039118  
PMID:9142130   PMID:9169414   PMID:9208206   PMID:9237484   PMID:9244230   PMID:9247138   PMID:9278526   PMID:9303529   PMID:9331901   PMID:9405702   PMID:9410890   PMID:9410891  
PMID:9454637   PMID:9477296   PMID:9486242   PMID:9536086   PMID:9665659   PMID:9679181   PMID:9681470   PMID:9692709   PMID:9758704   PMID:9769319   PMID:9786989   PMID:9801393  
PMID:9802886   PMID:9824677   PMID:9843821   PMID:9843834   PMID:9848082   PMID:9852587   PMID:9853118   PMID:9872314   PMID:9873204   PMID:9879685   PMID:9890982   PMID:9922227  
PMID:9932431   PMID:10027769   PMID:10037495   PMID:10077313   PMID:10090150   PMID:10330441   PMID:10338314   PMID:10349636   PMID:10362674   PMID:10395003   PMID:10407030   PMID:10444441  
PMID:10456061   PMID:10479702   PMID:10484454   PMID:10512307   PMID:10516139   PMID:10534440   PMID:10536054   PMID:10556946   PMID:10559836   PMID:10581072   PMID:10581083   PMID:10589702  
PMID:10590250   PMID:10591541   PMID:10611522   PMID:10613509   PMID:10623522   PMID:10652188   PMID:10677545   PMID:10690323   PMID:10690339   PMID:10709868   PMID:10727738   PMID:10744059  
PMID:10764216   PMID:10793157   PMID:10862698   PMID:10880573   PMID:10891583   PMID:10900019   PMID:10905473   PMID:10930440   PMID:10934256   PMID:10940322   PMID:10966931   PMID:10982771  
PMID:10995443   PMID:11015578   PMID:11027405   PMID:11029328   PMID:11042159   PMID:11058547   PMID:11062295   PMID:11076861   PMID:11115849   PMID:11146102   PMID:11152634   PMID:11158245  
PMID:11158630   PMID:11161004   PMID:11217851   PMID:11235982   PMID:11268022   PMID:11312611   PMID:11403933   PMID:11438492   PMID:11483302   PMID:11581289   PMID:11591728   PMID:11687280  
PMID:11700945   PMID:11709397   PMID:11717466   PMID:11717657   PMID:11729880   PMID:11739595   PMID:11829530   PMID:11850522   PMID:11867766   PMID:11904450   PMID:11907582   PMID:11920687  
PMID:11992469   PMID:12011984   PMID:12020853   PMID:12072412   PMID:12074580   PMID:12081826   PMID:12081996   PMID:12115690   PMID:12234657   PMID:12270041   PMID:12270125   PMID:12297264  
PMID:12351742   PMID:12379852   PMID:12381527   PMID:12397095   PMID:12409321   PMID:12438451   PMID:12456803   PMID:12466851   PMID:12477932   PMID:12509490   PMID:12562678   PMID:12571071  
PMID:12600881   PMID:12613893   PMID:12620898   PMID:12623792   PMID:12623875   PMID:12646421   PMID:12677017   PMID:12687699   PMID:12704728   PMID:12709511   PMID:12738065   PMID:12781920  
PMID:12788381   PMID:12794091   PMID:12798291   PMID:12798794   PMID:12810600   PMID:12829028   PMID:12834873   PMID:12834919   PMID:12864970   PMID:12886012   PMID:12888222   PMID:12900399  
PMID:14500669   PMID:14523625   PMID:14523813   PMID:14526232   PMID:14551061   PMID:14607521   PMID:14610273   PMID:14645704   PMID:14660484   PMID:14665440   PMID:14681479   PMID:14684357  
PMID:14701669   PMID:14704188   PMID:14706786   PMID:14707092   PMID:14722775   PMID:14766174   PMID:14976216   PMID:14983060   PMID:14996426   PMID:15010356   PMID:15026120   PMID:15075180  
PMID:15081365   PMID:15142832   PMID:15148562   PMID:15155789   PMID:15157956   PMID:15158692   PMID:15191553   PMID:15197473   PMID:15203939   PMID:15217783   PMID:15220315   PMID:15236237  
PMID:15238508   PMID:15246834   PMID:15287858   PMID:15297441   PMID:15302855   PMID:15319210   PMID:15328041   PMID:15350652   PMID:15380304   PMID:15381772   PMID:15469894   PMID:15486091  
PMID:15497153   PMID:15534476   PMID:15543804   PMID:15572147   PMID:15604044   PMID:15609086   PMID:15637297   PMID:15668387   PMID:15686955   PMID:15689952   PMID:15689958   PMID:15714282  
PMID:15729148   PMID:15845873   PMID:15890548   PMID:15917272   PMID:15923083   PMID:15961532   PMID:15983249   PMID:16000635   PMID:16007083   PMID:16009682   PMID:16024729   PMID:16026391  
PMID:16045907   PMID:16085056   PMID:16087361   PMID:16103686   PMID:16133146   PMID:16139176   PMID:16141072   PMID:16141073   PMID:16144633   PMID:16181097   PMID:16191394   PMID:16224055  
PMID:16226732   PMID:16246868   PMID:16256069   PMID:16260864   PMID:16272887   PMID:16297560   PMID:16301341   PMID:16344064   PMID:16344403   PMID:16365445   PMID:16397145   PMID:16427017  
PMID:16452688   PMID:16458438   PMID:16460714   PMID:16488973   PMID:16510300   PMID:16512683   PMID:16537391   PMID:16545353   PMID:16552082   PMID:16567525   PMID:16598948   PMID:16602821  
PMID:16733795   PMID:16735094   PMID:16735509   PMID:16807322   PMID:16807372   PMID:16857187   PMID:16876161   PMID:16916601   PMID:16959763   PMID:16963618   PMID:16973277   PMID:16987237  
PMID:17049179   PMID:17079272   PMID:17134781   PMID:17148677   PMID:17151270   PMID:17184520   PMID:17198882   PMID:17242280   PMID:17258180   PMID:17265179   PMID:17272813   PMID:17293453  
PMID:17306238   PMID:17307368   PMID:17350656   PMID:17387708   PMID:17394464   PMID:17395508   PMID:17419805   PMID:17446423   PMID:17452640   PMID:17459722   PMID:17492640   PMID:17507395  
PMID:17574882   PMID:17575085   PMID:17593140   PMID:17596536   PMID:17638388   PMID:17652601   PMID:17655958   PMID:17690195   PMID:17729288   PMID:17786240   PMID:17853069   PMID:17854382  
PMID:17854383   PMID:17885995   PMID:17916611   PMID:17922909   PMID:17928072   PMID:17951372   PMID:17954614   PMID:17959704   PMID:18006627   PMID:18007024   PMID:18046021   PMID:18057022  
PMID:18065432   PMID:18077344   PMID:18091753   PMID:18091979   PMID:18180383   PMID:18197485   PMID:18206129   PMID:18217802   PMID:18235988   PMID:18305236   PMID:18326824   PMID:18331873  
PMID:18342297   PMID:18400048   PMID:18400986   PMID:18406496   PMID:18413498   PMID:18421425   PMID:18433298   PMID:18440890   PMID:18448421   PMID:18461174   PMID:18502903   PMID:18508038  
PMID:18586241   PMID:18624924   PMID:18635601   PMID:18640116   PMID:18645184   PMID:18650379   PMID:18652592   PMID:18652891   PMID:18658051   PMID:18662545   PMID:18695006   PMID:18719000  
PMID:18754010   PMID:18786355   PMID:18799693   PMID:18812700   PMID:18836554   PMID:18852886   PMID:18930709   PMID:18952239   PMID:18952716   PMID:18953332   PMID:18987049   PMID:19038221  
PMID:19047200   PMID:19095954   PMID:19108575   PMID:19109486   PMID:19162139   PMID:19229108   PMID:19235728   PMID:19237426   PMID:19244529   PMID:19278978   PMID:19283362   PMID:19306865  
PMID:19307451   PMID:19340535   PMID:19358992   PMID:19360314   PMID:19362797   PMID:19407124   PMID:19429176   PMID:19470653   PMID:19478875   PMID:19479987   PMID:19494147   PMID:19531381  
PMID:19538708   PMID:19542095   PMID:19545548   PMID:19559786   PMID:19571147   PMID:19580782   PMID:19605412   PMID:19607794   PMID:19615412   PMID:19616617   PMID:19652084   PMID:19652483  
PMID:19679819   PMID:19706695   PMID:19718040   PMID:19730405   PMID:19734360   PMID:19766235   PMID:19770398   PMID:19775503   PMID:19800018   PMID:19800948   PMID:19845829   PMID:19855026  
PMID:19926812   PMID:19931630   PMID:19934009   PMID:19936028   PMID:19940861   PMID:19959818   PMID:20080794   PMID:20124730   PMID:20147620   PMID:20158465   PMID:20164327   PMID:20304785  
PMID:20392943   PMID:20435320   PMID:20436479   PMID:20438808   PMID:20483958   PMID:20507551   PMID:20530114   PMID:20543469   PMID:20561153   PMID:20581102   PMID:20624383   PMID:20638384  
PMID:20651700   PMID:20655878   PMID:20661721   PMID:20662604   PMID:20707635   PMID:20720107   PMID:20727829   PMID:20739607   PMID:20826310   PMID:20845474   PMID:20921441   PMID:20944551  
PMID:20951772   PMID:20953358   PMID:21073925   PMID:21082337   PMID:21102461   PMID:21125668   PMID:21148012   PMID:21179208   PMID:21267068   PMID:21282319   PMID:21331324   PMID:21363890  
PMID:21383158   PMID:21434910   PMID:21470341   PMID:21471366   PMID:21508214   PMID:21539806   PMID:21606640   PMID:21613472   PMID:21615722   PMID:21651902   PMID:21756313   PMID:21777607  
PMID:21780643   PMID:21791288   PMID:21813683   PMID:21825026   PMID:21849632   PMID:21858821   PMID:21873635   PMID:21884692   PMID:21890687   PMID:21896719   PMID:21935943   PMID:21943598  
PMID:21943603   PMID:21945318   PMID:21960957   PMID:21965681   PMID:21976486   PMID:21989918   PMID:22027181   PMID:22036570   PMID:22058155   PMID:22090484   PMID:22123949   PMID:22205701  
PMID:22262671   PMID:22262891   PMID:22316281   PMID:22351125   PMID:22378773   PMID:22486744   PMID:22493004   PMID:22522563   PMID:22550140   PMID:22580898   PMID:22613021   PMID:22688956  
PMID:22798524   PMID:22820053   PMID:22828515   PMID:22833130   PMID:22891311   PMID:22932783   PMID:22937058   PMID:22950758   PMID:22952904   PMID:23012472   PMID:23064802   PMID:23091050  
PMID:23100421   PMID:23142661   PMID:23202294   PMID:23277581   PMID:23312518   PMID:23359715   PMID:23362871   PMID:23434456   PMID:23478408   PMID:23504347   PMID:23507581   PMID:23576613  
PMID:23608660   PMID:23616539   PMID:23639802   PMID:23649862   PMID:23680665   PMID:23684982   PMID:23719162   PMID:23774658   PMID:23861145   PMID:23904594   PMID:23940011   PMID:23948215  
PMID:23955171   PMID:24032714   PMID:24076963   PMID:24127602   PMID:24133409   PMID:24154525   PMID:24155296   PMID:24162656   PMID:24191004   PMID:24235139   PMID:24305053   PMID:24351932  
PMID:24366262   PMID:24498331   PMID:24602444   PMID:24624894   PMID:24643800   PMID:24657074   PMID:24671193   PMID:24723342   PMID:24760996   PMID:24782615   PMID:24812663   PMID:24813792  
PMID:24899708   PMID:24911015   PMID:24952961   PMID:24981859   PMID:25017185   PMID:25025574   PMID:25071457   PMID:25125509   PMID:25129479   PMID:25151305   PMID:25214536   PMID:25326127  
PMID:25344365   PMID:25389974   PMID:25391901   PMID:25392498   PMID:25398110   PMID:25511929   PMID:25595735   PMID:25621792   PMID:25664654   PMID:25678382   PMID:25684045   PMID:25716315  
PMID:25732085   PMID:25749441   PMID:25813085   PMID:25823749   PMID:25837940   PMID:25865048   PMID:25868900   PMID:25870540   PMID:25892053   PMID:25936505   PMID:26009878   PMID:26152695  
PMID:26156989   PMID:26173391   PMID:26235957   PMID:26247728   PMID:26324446   PMID:26332085   PMID:26427435   PMID:26483274   PMID:26503494   PMID:26604149   PMID:26617487   PMID:26647426  
PMID:26648027   PMID:26671618   PMID:26727548   PMID:26791826   PMID:26861996   PMID:26883268   PMID:26976926   PMID:27006199   PMID:27032391   PMID:27076429   PMID:27135215   PMID:27171264  
PMID:27178324   PMID:27270085   PMID:27282485   PMID:27296112   PMID:27477497   PMID:27487211   PMID:27568519   PMID:27601184   PMID:27616062   PMID:27618674   PMID:27634009   PMID:27672360  
PMID:27779093   PMID:27784691   PMID:27822504   PMID:27976716   PMID:27991851   PMID:28013342   PMID:28123012   PMID:28167615   PMID:28387937   PMID:28420791   PMID:28577305   PMID:28622359  
PMID:28666850   PMID:28671186   PMID:28671696   PMID:28684471   PMID:28705804   PMID:28725180   PMID:28731029   PMID:28800639   PMID:28942923   PMID:28951000   PMID:28973166   PMID:28974418  
PMID:28985566   PMID:29031500   PMID:29066445   PMID:29093670   PMID:29110178   PMID:29123082   PMID:29183804   PMID:29192291   PMID:29233575   PMID:29234274   PMID:29268095   PMID:29374161  
PMID:29379870   PMID:29394072   PMID:29438803   PMID:29444423   PMID:29462275   PMID:29489747   PMID:29556030   PMID:29572434   PMID:29577585   PMID:29605772   PMID:29678764   PMID:29748916  
PMID:29790927   PMID:29911171   PMID:29914853   PMID:29915136   PMID:30028847   PMID:30143658   PMID:30177704   PMID:30193808   PMID:30236982   PMID:30257978   PMID:30456293   PMID:30472119  
PMID:30482690   PMID:30559475   PMID:30727847   PMID:30867247   PMID:30918408   PMID:30944354   PMID:30954227   PMID:31043586   PMID:31091127   PMID:31124076   PMID:31153646   PMID:31167127  
PMID:31241990   PMID:31259693   PMID:31268770   PMID:31328777   PMID:31609204   PMID:31666704   PMID:31682159   PMID:31742355   PMID:31746324   PMID:31805977   PMID:31806757   PMID:31863649  
PMID:31955944   PMID:31969659   PMID:31989159   PMID:31996852   PMID:32017713   PMID:32066723   PMID:32101284   PMID:32113678   PMID:32193098   PMID:32241803   PMID:32325033   PMID:32343709  
PMID:32343840   PMID:32420617   PMID:32427844   PMID:32580946   PMID:32602839   PMID:32656734   PMID:33016877   PMID:33288908   PMID:33335094   PMID:33434144   PMID:33653689   PMID:33744254  
PMID:33789083   PMID:33831408   PMID:33897893   PMID:33925396   PMID:34004146   PMID:34095148   PMID:34127535   PMID:34387544   PMID:34433854   PMID:34644112   PMID:34705510   PMID:34720852  


Comparative Map Data
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm395118,004,904 - 118,096,905 (+)NCBIGRCm39mm39
GRCm39 Ensembl5117,919,097 - 118,096,905 (+)Ensembl
GRCm385117,866,839 - 117,958,840 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5117,781,032 - 117,958,840 (+)EnsemblGRCm38mm10GRCm38
MGSCv375118,317,128 - 118,403,822 (+)NCBIGRCm37mm9NCBIm37
MGSCv365118,128,149 - 118,214,843 (+)NCBImm8
Celera5114,958,747 - 115,046,830 (+)NCBICelera
Cytogenetic Map5FNCBI
cM Map557.29NCBI
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl12117,208,142 - 117,452,170 (-)EnsemblGRCh38hg38GRCh38
GRCh3812117,208,142 - 117,361,626 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3712117,645,947 - 117,799,431 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3612116,135,362 - 116,283,965 (-)NCBINCBI36hg18NCBI36
Build 3412116,113,698 - 116,262,302NCBI
Celera12117,280,475 - 117,430,209 (-)NCBI
Cytogenetic Map12q24.22NCBI
HuRef12114,655,115 - 114,808,727 (-)NCBIHuRef
CHM1_112117,611,241 - 117,767,258 (-)NCBICHM1_1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
mRatBN7.21238,615,111 - 38,795,492 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl1238,626,714 - 38,710,945 (-)Ensembl
Rnor_6.01244,214,949 - 44,405,530 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1244,213,943 - 44,520,341 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01246,049,288 - 46,209,569 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41239,812,500 - 39,869,484 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11239,675,108 - 39,732,872 (-)NCBI
Celera1240,283,655 - 40,368,674 (-)NCBICelera
RH 3.4 Map12717.0RGD
RH 3.4 Map12718.8RGD
Cytogenetic Map12q16NCBI
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
ChiLan1.0 EnsemblNW_00495545513,797,545 - 13,972,566 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495545513,797,557 - 13,978,402 (+)NCBIChiLan1.0ChiLan1.0
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
PanPan1.112118,163,655 - 118,314,005 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl12118,163,655 - 118,314,005 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v012114,784,232 - 114,938,385 (-)NCBIMhudiblu_PPA_v0panPan3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
CanFam3.12613,787,341 - 13,895,176 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2613,786,309 - 13,962,332 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2613,781,845 - 13,865,309 (-)NCBI
ROS_Cfam_1.02614,042,033 - 14,222,209 (-)NCBI
ROS_Cfam_1.0 Ensembl2614,044,400 - 14,151,070 (-)Ensembl
UMICH_Zoey_3.12614,009,781 - 14,093,258 (-)NCBI
UNSW_CanFamBas_1.02614,087,144 - 14,170,688 (-)NCBI
UU_Cfam_GSD_1.02614,122,943 - 14,206,510 (-)NCBI
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
HiC_Itri_2NW_024405118154,176,906 - 154,267,437 (-)NCBI
SpeTri2.0NW_0049365585,162,471 - 5,302,488 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
Sscrofa11.1 Ensembl1435,113,184 - 35,295,972 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11435,112,898 - 35,299,297 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21437,401,967 - 37,515,427 (+)NCBISscrofa10.2Sscrofa10.2susScr3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
ChlSab1.111112,642,374 - 112,673,882 (-)NCBIChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666037132,411,769 - 132,561,385 (+)NCBIVero_WHO_p1.0
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
HetGla 1.0NW_00462474715,940,614 - 16,118,051 (+)NCBIHetGla_female_1.0hetGla2

Position Markers
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm385117,879,630 - 117,879,777UniSTSGRCm38
MGSCv375118,329,639 - 118,329,786UniSTSGRCm37
Celera5114,971,378 - 114,971,509UniSTS
Cytogenetic Map5FUniSTS
cM Map564.0UniSTS
Whitehead Genetic551.4UniSTS
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm385117,910,948 - 117,911,226UniSTSGRCm38
GRCm385117,911,019 - 117,911,226UniSTSGRCm38
MGSCv375118,360,957 - 118,361,235UniSTSGRCm37
MGSCv375118,361,028 - 118,361,235UniSTSGRCm37
Celera5115,003,727 - 115,004,023UniSTS
Celera5115,003,798 - 115,004,023UniSTS
Cytogenetic Map5FUniSTS
cM Map564.0UniSTS
cM Map5 UniSTS
Whitehead Genetic551.4UniSTS
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm385117,932,225 - 117,932,347UniSTSGRCm38
MGSCv375118,382,234 - 118,382,356UniSTSGRCm37
Celera5115,025,026 - 115,025,148UniSTS
Cytogenetic Map5FUniSTS
cM Map564.0UniSTS
Whitehead Genetic551.4UniSTS
Mouse AssemblyChrPosition (strand)SourceJBrowse
MGSCv375118,317,423 - 118,317,901UniSTSGRCm37
Celera5114,959,042 - 114,959,520UniSTS
Cytogenetic Map5FUniSTS
cM Map565.0UniSTS
cM Map565.0UniSTS
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm385117,867,129 - 117,867,669UniSTSGRCm38
MGSCv375118,317,138 - 118,317,678UniSTSGRCm37
Celera5114,958,757 - 114,959,297UniSTS
Cytogenetic Map5FUniSTS
cM Map565.0UniSTS
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm385117,900,498 - 117,900,585UniSTSGRCm38
MGSCv375118,350,507 - 118,350,594UniSTSGRCm37
Celera5114,993,278 - 114,993,365UniSTS
Cytogenetic Map5FUniSTS
cM Map565.0UniSTS
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm385117,867,490 - 117,867,929UniSTSGRCm38
MGSCv375118,317,499 - 118,317,938UniSTSGRCm37
Celera5114,959,118 - 114,959,557UniSTS
Cytogenetic Map5FUniSTS
cM Map565.0UniSTS
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map5FUniSTS
cM Map565.0UniSTS
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm385117,867,414 - 117,867,892UniSTSGRCm38
MGSCv375118,317,423 - 118,317,901UniSTSGRCm37
Celera5114,959,042 - 114,959,520UniSTS
Cytogenetic Map5FUniSTS

QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
11341716Rvfs3_mRift Valley fever susceptibility 3 (mouse)526236236138457140Mouse
4142064Tmc1m4_mTmc1 modifier 4 (mouse)Not determined554342835126924008Mouse
26884395Humsd2_mhumerus midshaft diameter 2, 10 week (mouse)569900000132500000Mouse
27226719Tibw6_mtibia width 6, proximal, 16 week (mouse)572700000140000000Mouse
13506928Recrq8_mrecombination rate in male meiosis QTL 8 (mouse)574300000132500000Mouse
25314315Mlh1fc4_mMLH1 foci count 4 (mouse)574300000132500000Mouse
1357431Cia27_mcollagen induced arthritis 27 (mouse)Not determined575154687119880564Mouse
1300801Drb2_mdopamine receptor binding 2 (mouse)Not determined587239005121239199Mouse
1301399Cpfd3_mcerebellum pattern fissures (mouse)Not determined587239005121239199Mouse
1301126Bwem1_mbody weight day 30 males 1 (mouse)Not determined587239005121239199Mouse
10043958Chldq12_mcholesterol and HDL QTL 12 (mouse)Not determined587239005121239199Mouse
13464241Ahl18_mage related hearing loss, early onset 18 (mouse)587239005121239199Mouse
1357725Eae39_mexperimental allergic encephalomyelitis 39 (mouse)Not determined589271017118725963Mouse
1300968Skts4_mskin tumor susceptibility 4 (mouse)Not determined589271017124100176Mouse
1301362Prnr1_mprion resistance 1 (mouse)Not determined589271017146851125Mouse
11049562Lmr24f_mleishmaniasis resistance 24f (mouse)590173096124173175Mouse
1301457Cfsw2_mcystic fibrosis survival to weaning 2 (mouse)Not determined590413140124413285Mouse
1300993Hycdc_mhypercapnic duty cycle (mouse)Not determined590413140124413285Mouse
9587780Afw16_mabdominal fat weight QTL 16 (mouse)Not determined592682300126682419Mouse
1301974Chab7_mcholesterol absorption 7 (mouse)Not determined595085348129085464Mouse
1357644Egrd1_mearly growth rate, direct effect 1 (mouse)Not determined595286714129286920Mouse
1558774Lith17_mlithogenic gene 17 (mouse)Not determined595317683129317856Mouse
10402486Dipa1_mdrug induced psychomotor activation 1 (mouse)Not determined595317683129317856Mouse
13464244Ahl19_mage related hearing loss, early onset 19 (mouse)595317683129317856Mouse
1300940Actd3_mactivity-distance traveled 3 (mouse)Not determined596172519130172667Mouse
1300659Pcd8ts1_mp-glycoprotein positive CD8 T cell subset 1 (mouse)Not determined596883692130883925Mouse
1301858Smdq1_msegregation of mitochondrial DNA QTL 1 (mouse)Not determined596883692130883925Mouse
4141519Hmtb5_mhemostasis and thrombosis bleeding time 5 (mouse)Not determined99801563126805880Mouse
12904945Tammq2_mtibialis anterior muscle mass QTL 2 (mouse)5100527900134527900Mouse
12904959Smmq1_msoleus muscle mass QTL 1 (mouse)5100527900134527900Mouse
12859290Criq2_mCitrobacter rodentium infection QTL 2 (mouse)5101194514135194514Mouse
1301624Aevm2_mautoimmune extremity vasculitis in MRL mice 2 (mouse)Not determined5101725767135725963Mouse
14746986Manh58_mmandible shape 58 (mouse)5102308218136308218Mouse
11532736Sluc33b_msusceptibility to lung cancer 33b (mouse)5102806972136807131Mouse
11528550Sluc33_msusceptibility to lung cancer 33 (mouse)5104239005120573921Mouse
10412202Bbaa26_mB.burgdorferi-associated arthritis 26 (mouse)Not determined5104435822138557193Mouse
10412239Alpq7_malcohol preference QTL 7 (mouse)Not determined5104567876138567876Mouse
4142473Chlq11_mcirculating hormone level QTL 11 (mouse)Not determined5107829235141829348Mouse
10043890Trigq4_mtriglyceride QTL 4 (mouse)Not determined5107829235141829348Mouse
13464243Ahl20_mage related hearing loss, early onset 20 (mouse)5107829235141829348Mouse
4141139Hmtb4_mhemostasis and thrombosis rebleeding time 4 (mouse)Not determined108614643126805880Mouse
10412197Bbaa25_mB.burgdorferi-associated arthritis 25 (mouse)Not determined5109090176143090317Mouse
13464251Ahl21_mage related hearing loss, early onset 21 (mouse)5109090176143090317Mouse
1301543Hypch_mhypercholesterolemia (mouse)Not determined5109090758139133150Mouse
1300913Bwefm_mbody weight females and males day 10 (mouse)Not determined5109362284143362395Mouse
4141652Mrdq2_mmodifier of retinal degeneration QTL 2 (mouse)Not determined110105240117955608Mouse
1301102Cia14_mcollagen induced arthritis 14 (mouse)Not determined5113172519138557193Mouse
1357662Lprq4_mlipoprotein QTL 4 (mouse)Not determined5113883692129555542Mouse
1300827Cora1_mcorrelation in cytokine production 1 (mouse)Not determined5115128044149128176Mouse
1301226Bbaa2_mB.burgdorferi-associated arthritis 2 (mouse)Not determined5115128044149128176Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:3158
Count of miRNA genes:894
Interacting mature miRNAs:1241
Transcripts:ENSMUST00000086451, ENSMUST00000102557, ENSMUST00000124194, ENSMUST00000138554, ENSMUST00000138579, ENSMUST00000142742, ENSMUST00000171055
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (
For more information about miRGate, see PMID:25858286 or access the full paper here.



Reference Sequences
RefSeq Acc Id: ENSMUST00000086451   ⟹   ENSMUSP00000138506
RefSeq Status:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5117,980,251 - 118,092,429 (+)Ensembl
GRCm38.p6 Ensembl5117,842,186 - 117,954,364 (+)Ensembl
RefSeq Acc Id: ENSMUST00000102557   ⟹   ENSMUSP00000099617
RefSeq Status:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5118,005,179 - 118,091,974 (+)Ensembl
GRCm38.p6 Ensembl5117,867,114 - 117,953,909 (+)Ensembl
RefSeq Acc Id: ENSMUST00000124194
RefSeq Status:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5117,919,120 - 118,005,151 (+)Ensembl
GRCm38.p6 Ensembl5117,781,055 - 117,867,086 (+)Ensembl
RefSeq Acc Id: ENSMUST00000138554
RefSeq Status:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5118,057,240 - 118,063,796 (+)Ensembl
GRCm38.p6 Ensembl5117,919,175 - 117,925,731 (+)Ensembl
RefSeq Acc Id: ENSMUST00000138579   ⟹   ENSMUSP00000138176
RefSeq Status:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5117,919,097 - 118,005,521 (+)Ensembl
GRCm38.p6 Ensembl5117,781,032 - 117,867,456 (+)Ensembl
RefSeq Acc Id: ENSMUST00000142742   ⟹   ENSMUSP00000120421
RefSeq Status:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5117,979,915 - 118,096,905 (+)Ensembl
GRCm38.p6 Ensembl5117,841,850 - 117,958,840 (+)Ensembl
RefSeq Acc Id: ENSMUST00000171055   ⟹   ENSMUSP00000127432
RefSeq Status:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5118,005,184 - 118,091,878 (+)Ensembl
GRCm38.p6 Ensembl5117,867,119 - 117,953,813 (+)Ensembl
RefSeq Acc Id: NM_008712   ⟹   NP_032738
RefSeq Status: VALIDATED
Mouse AssemblyChrPosition (strand)Source
GRCm395118,004,904 - 118,096,905 (+)NCBI
GRCm385117,866,839 - 117,958,840 (+)NCBI
MGSCv375118,317,128 - 118,403,822 (+)RGD
Celera5114,958,747 - 115,046,830 (+)RGD
Reference Sequences
RefSeq Acc Id: NP_032738   ⟸   NM_008712
- UniProtKB: Q9Z0J4 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000138506   ⟸   ENSMUST00000086451
RefSeq Acc Id: ENSMUSP00000138176   ⟸   ENSMUST00000138579
RefSeq Acc Id: ENSMUSP00000127432   ⟸   ENSMUST00000171055
RefSeq Acc Id: ENSMUSP00000120421   ⟸   ENSMUST00000142742
RefSeq Acc Id: ENSMUSP00000099617   ⟸   ENSMUST00000102557
Protein Domains
FAD-binding FR-type   Flavodoxin-like   PDZ

RGD ID:6887820
Promoter ID:EPDNEW_M7361
Type:initiation region
Description:Mus musculus nitric oxide synthase 1, neuronal , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database,
Experiment Methods:Single-end sequencing.
Mouse AssemblyChrPosition (strand)Source
GRCm385117,949,587 - 117,949,647EPDNEW
RGD ID:6837954
Promoter ID:MM_KWN:43767
SO ACC ID:SO:0000170
Tissues & Cell Lines:Brain
Transcripts:ENSMUST00000102557,   UC008ZFY.1
Mouse AssemblyChrPosition (strand)Source
MGSCv365118,317,441 - 118,317,941 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:97360 AgrOrtholog
Ensembl Genes ENSMUSG00000029361 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000099617 UniProtKB/TrEMBL
  ENSMUSP00000120421 UniProtKB/Swiss-Prot
  ENSMUSP00000127432 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000138176 UniProtKB/TrEMBL
  ENSMUSP00000138506 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000086451 UniProtKB/TrEMBL
  ENSMUST00000102557 UniProtKB/TrEMBL
  ENSMUST00000138579 UniProtKB/TrEMBL
  ENSMUST00000142742 UniProtKB/Swiss-Prot
  ENSMUST00000171055 ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH 1.20.990.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro CysJ-like_FAD-binding UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FAD-bd_FR_type UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Flavdoxin-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Flavodoxin/NO_synth UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Flavoprot_Pyr_Nucl_cyt_Rdtase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Flavoprotein-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FNR_nucleotide-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NADPH_Cyt_P450_Rdtase_alpha UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NOS_euk UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NOS_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NOS_N_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  OxRdtase_FAD/NAD-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PDZ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PDZ_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Riboflavin_synthase-like_b-brl UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:18125 UniProtKB/Swiss-Prot
Pfam FAD_binding_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Flavodoxin_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NAD_binding_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NO_synthase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PDZ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Nos1 PhenoGen
PIRSF NOS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FPNCR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NOS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PDZ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART PDZ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF50156 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF52218 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF52343 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF56512 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF63380 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt Secondary Q3UR10 UniProtKB/Swiss-Prot
  Q64208 UniProtKB/Swiss-Prot

Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-04-05 Nos1  nitric oxide synthase 1, neuronal  2310005C01Rik  RIKEN cDNA 2310005C01 gene  Data Merged 737654 PROVISIONAL