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Gene: Nos1 (nitric oxide synthase 1, neuronal) Mus musculus
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Symbol: Nos1
Name: nitric oxide synthase 1, neuronal
Description: Exhibits nitric-oxide synthase activity. Involved in several processes, including nitric oxide biosynthetic process; positive regulation of nitrogen compound metabolic process; and regulation of ion transport. Localizes to several cellular components, including T-tubule; Z disc; and calyx of Held. Colocalizes with caveola. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Used to study achalasia and hypertrophic pyloric stenosis. Human ortholog(s) of this gene implicated in Alzheimer's disease; Parkinson's disease; asthma; cystic fibrosis; and hypertrophic pyloric stenosis. Orthologous to human NOS1 (nitric oxide synthase 1); PARTICIPATES IN AGAT deficiency pathway; arginine and proline metabolic pathway; guanidinoacetate methyltransferase deficiency pathway; INTERACTS WITH (3,4-dihydroxyphenyl)acetic acid; (S)-amphetamine; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2310005C01Rik; bNOS; constitutive NOS; N-NOS; NC-NOS; neuronal nitric oxide synthase; neuronal NOS; nitric oxide synthase, brain; nNOS; NO; NOS; NOS type I; Nos-1; NOS-I; peptidyl-cysteine S-nitrosylase NOS1; RIKEN cDNA 2310005C01 gene
Orthologs:
Homo sapiens (human) : NOS1 (nitric oxide synthase 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Nos1 (nitric oxide synthase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nos1 (nitric oxide synthase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : NOS1 (nitric oxide synthase 1)
Canis lupus familiaris (dog) : NOS1 (nitric oxide synthase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nos1 (nitric oxide synthase 1)
Sus scrofa (pig) : NOS1 (nitric oxide synthase 1)
Heterocephalus glaber (naked mole-rat) : Nos1 (nitric oxide synthase 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl5117,781,032 - 117,958,840 (+)EnsemblGRCm38mm10GRCm38
GRCm385117,866,839 - 117,958,840 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv375118,317,128 - 118,403,822 (+)NCBIGRCm37mm9NCBIm37
MGSCv365118,128,149 - 118,214,843 (+)NCBImm8
Celera5114,958,747 - 115,046,830 (+)NCBICelera
Cytogenetic Map5FNCBI
cM Map557.29NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
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Additional Information

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Nomenclature History
 
More on Nos1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10991
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-07-28
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.