Ache (acetylcholinesterase) - Rat Genome Database

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Gene: Ache (acetylcholinesterase) Rattus norvegicus
Analyze
Symbol: Ache
Name: acetylcholinesterase
RGD ID: 69313
Description: Enables acetylcholine binding activity; acetylcholinesterase activity; and choline binding activity. Involved in several processes, including acetylcholine catabolic process; positive regulation of neurogenesis; and synapse assembly. Located in several cellular components, including endoplasmic reticulum; neuronal cell body; and synaptic membrane. Is active in neuromuscular junction and synaptic cleft. Biomarker of acute stress disorder and leptospirosis. Human ortholog(s) of this gene implicated in Alzheimer's disease; epilepsy; and myasthenia gravis. Orthologous to human ACHE (acetylcholinesterase (Cartwright blood group)); PARTICIPATES IN acetylcholine metabolic pathway; acetylcholine signaling pathway via muscarinic acetylcholine receptor; acetylcholine signaling pathway via nicotinic acetylcholine receptor; INTERACTS WITH (+)-alpha-tocopherol; (+)-pilocarpine; (R)-lipoic acid.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: glycolipid-anchored form of acetylcholinesterase; Hache
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21219,407,359 - 19,413,713 (-)NCBI
Rnor_6.0 Ensembl1222,472,358 - 22,478,753 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01222,472,358 - 22,477,052 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01224,487,632 - 24,491,360 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1221,207,976 - 21,212,604 (-)NCBICelera
Cytogenetic Map12q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-alpha-tocopherol  (EXP)
(+)-pilocarpine  (EXP,ISO)
(+)-syringaresinol beta-D-glucoside  (ISO)
(20R)-protopanaxadiol  (ISO)
(R)-lipoic acid  (EXP,ISO)
(S)-colchicine  (ISO)
(S)-nicotine  (EXP)
1,2-dichloroethane  (EXP)
1,2-dimethylhydrazine  (ISO)
1-[(2,3,4-trimethoxyphenyl)methyl]piperazine  (EXP)
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine  (ISO)
17beta-estradiol  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (EXP)
2,3,5,6,7,8-hexahydro-1H-cyclopenta[b]quinolin-9-amine  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2,4,6-tribromophenol  (ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2-methoxyethanol  (EXP)
2-methyl-6-(phenylethynyl)pyridine  (EXP)
3,4-dihydroxybenzaldehyde  (ISO)
3,4-dihydroxybenzoic acid  (ISO)
3,5,6-trichloro-2-pyridinol  (ISO)
3,5,6-trichloropyridine-2-one  (ISO)
3-nitropropanoic acid  (EXP)
4,4'-sulfonyldiphenol  (ISO)
5-chloro-7-iodoquinolin-8-ol  (ISO)
6-Acetylmorphine  (ISO)
6-propyl-2-thiouracil  (EXP)
9-aminoacridine  (ISO)
acephate  (EXP,ISO)
acepromazine  (ISO)
acetaldehyde  (ISO)
acetaldehyde oxime  (ISO)
acetamide  (EXP)
acetic acid 1-azabicyclo[2.2.2]octan-3-yl ester  (EXP)
acetylcholine  (EXP,ISO)
acrylamide  (EXP)
alachlor  (EXP,ISO)
aldehydo-D-glucose  (ISO)
aldicarb  (EXP,ISO)
alendronic acid  (ISO)
all-trans-retinoic acid  (ISO)
alpha-D-galactose  (ISO)
aluminium atom  (EXP)
aluminium(0)  (EXP)
aminocarb  (ISO)
amitriptyline  (EXP,ISO)
amodiaquine  (ISO)
anthra[1,9-cd]pyrazol-6(2H)-one  (EXP)
apigenin  (EXP)
Aroclor 1254  (EXP)
arsane  (EXP,ISO)
arsenic atom  (EXP,ISO)
arsenous acid  (EXP)
aspartame  (EXP,ISO)
atropine  (EXP,ISO)
azamethiphos  (EXP,ISO)
azinphos-methyl  (ISO)
bacitracin  (ISO)
baicalin  (EXP)
bambuterol  (ISO)
barium chloride  (EXP)
barium(0)  (EXP)
bendiocarb  (EXP,ISO)
Bensulide  (EXP,ISO)
benzo[a]pyrene  (EXP,ISO)
berberine  (EXP)
Besigomsin  (ISO)
bexarotene  (EXP)
bifenthrin  (EXP)
bis(2-chloroethyl) sulfide  (EXP,ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol A diglycidyl ether  (EXP,ISO)
bisphenol F  (ISO)
bucladesine  (EXP)
butyrylthiocholine  (ISO)
C60 fullerene  (EXP)
cadmium atom  (EXP,ISO)
cadmium dichloride  (EXP,ISO)
cadmium sulfate  (EXP)
caffeine  (EXP)
calycosin  (EXP)
canagliflozin  (EXP)
carbachol  (ISO)
carbamate ester  (ISO)
carbaryl  (EXP,ISO)
carbendazim  (EXP)
carbofuran  (EXP,ISO)
Carbophenothion  (EXP)
carbosulfan  (EXP)
carnosine  (ISO)
carvacrol  (EXP)
catalpol  (ISO)
celecoxib  (ISO)
Chebulinic acid  (ISO)
chlorfenvinfos  (EXP,ISO)
chlorite  (ISO)
chlorogenic acid  (ISO)
chlorohydrocarbon  (EXP)
chlorpromazine  (ISO)
chlorpyrifos  (EXP,ISO)
cholesterol  (ISO)
choline  (ISO)
cis-caffeic acid  (EXP)
cisplatin  (ISO)
clofibrate  (EXP)
cobalt dichloride  (EXP)
colforsin daropate hydrochloride  (EXP)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
copper(II) chloride  (EXP,ISO)
copper(II) sulfate  (ISO)
cordycepin  (EXP)
corticosterone  (ISO)
coumaphos  (ISO)
coumarin  (ISO)
Crotoxyphos  (ISO)
Cryptotanshinone  (ISO)
cucurbit[7]uril  (ISO)
curcumin  (EXP,ISO)
cyclosporin A  (ISO)
cyfluthrin  (EXP)
cypermethrin  (EXP)
D-glucose  (ISO)
daidzein 7-O-beta-D-glucoside  (EXP)
DDT  (ISO)
decabromodiphenyl ether  (ISO)
Decursin  (ISO)
demethoxycurcumin  (EXP)
demeton-S-methyl  (ISO)
dequalinium  (ISO)
desipramine  (ISO)
dexamethasone  (EXP)
dextran sulfate  (ISO)
Diacetylmonoxime  (ISO)
diarsenic trioxide  (EXP)
diazinon  (EXP,ISO)
diazoxon  (EXP,ISO)
dichlorvos  (EXP,ISO)
diclofop-methyl  (EXP)
dicrotophos  (EXP,ISO)
difenoconazole  (EXP)
diisopropyl fluorophosphate  (EXP,ISO)
dimethoate  (EXP,ISO)
dimethylarsinic acid  (ISO)
dimethylmercury  (EXP)
dioxygen  (EXP,ISO)
disodium selenite  (ISO)
disulfiram  (EXP)
disulfoton  (EXP)
dithionite(2-)  (ISO)
donepezil hydrochloride  (EXP,ISO)
doxepin  (ISO)
doxorubicin  (ISO)
DPCPX  (EXP)
ecothiopate iodide  (ISO)
edrophonium  (ISO)
elemental selenium  (EXP)
endosulfan  (EXP)
EPTC  (EXP)
ergothioneine  (ISO)
ethanol  (EXP,ISO)
ethoprophos  (EXP,ISO)
ethylbenzene  (EXP)
ethylenediaminetetraacetic acid  (ISO)
Ethylenethiourea  (EXP,ISO)
eugenol  (EXP)
fenamiphos  (EXP,ISO)
fenitrothion  (EXP,ISO)
fenoxycarb  (EXP)
fenthion  (EXP,ISO)
fenvalerate  (EXP)
ferric oxide  (ISO)
ferulic acid  (EXP)
folic acid  (ISO)
formetanate  (EXP)
Fusaric acid  (EXP)
galactose  (ISO)
galangin  (EXP)
galanthamine  (EXP,ISO)
galanthamine Trifluoroacetic acid  (EXP,ISO)
gamma-hexachlorocyclohexane  (EXP,ISO)
genistein  (EXP,ISO)
genistein 7-O-beta-D-glucoside  (EXP)
geraniol  (EXP)
ginsenoside Rg1  (ISO)
glucose  (ISO)
glycyrrhizinic acid  (EXP)
glyphosate  (EXP,ISO)
heptenophos  (ISO)
herbicide  (ISO)
heroin  (ISO)
hesperidin  (EXP)
high-density lipoprotein cholesterol  (ISO)
HLo7  (EXP,ISO)
homocysteine  (ISO)
huperzine A  (EXP,ISO)
hydrazinecarbothioamide  (ISO)
hypochlorous acid  (ISO)
ifosfamide  (EXP)
imidacloprid  (EXP)
imipramine  (ISO)
indinavir  (ISO)
indole-3-butyric acid  (EXP)
irinotecan  (EXP)
Irisflorentin  (EXP)
isocarbophos  (EXP,ISO)
kaempferol  (EXP)
Kokusaginine  (ISO)
L-ascorbic acid  (EXP,ISO)
L-glutamic acid  (ISO)
lead diacetate  (EXP,ISO)
lead(0)  (EXP,ISO)
lead(2+)  (EXP,ISO)
Licochalcone B  (ISO)
lipoic acid  (EXP,ISO)
lisinopril dihydrate  (EXP,ISO)
lithium chloride  (ISO)
loganin  (ISO)
luteolin  (EXP)
lycopene  (EXP)
malaoxon  (EXP,ISO)
malathion  (EXP,ISO)
mancozeb  (EXP)
maneb  (EXP,ISO)
manganese atom  (EXP,ISO)
manganese dioxide  (EXP)
manganese(0)  (EXP,ISO)
manganese(II) chloride  (EXP,ISO)
mangiferin  (ISO)
melatonin  (EXP)
memantine  (EXP)
mercury atom  (ISO)
mercury dichloride  (EXP)
mercury(0)  (ISO)
metformin  (ISO)
methamidophos  (EXP,ISO)
methanol  (EXP,ISO)
methiocarb  (EXP)
methomyl  (EXP,ISO)
methotrexate  (ISO)
methylmercury chloride  (EXP)
metoclopramide  (ISO)
mevinphos  (EXP,ISO)
Mipafox  (EXP,ISO)
monocrotophos  (EXP,ISO)
monosodium L-glutamate  (EXP)
morin  (EXP)
morphine  (ISO)
Muscarine  (ISO)
N(gamma)-nitro-L-arginine methyl ester  (EXP)
N,N-diethyl-m-toluamide  (EXP,ISO)
N-[[4-[2-(dimethylamino)ethoxy]phenyl]methyl]-3,4-dimethoxybenzamide  (ISO)
N-acetyl-L-cysteine  (EXP,ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
N-methyl-4-phenylpyridinium  (EXP,ISO)
N-Nitrosodi-n-butylamine  (ISO)
N-Nitrosopyrrolidine  (ISO)
N1'-[2-[[5-[(dimethylamino)methyl]-2-furanyl]methylthio]ethyl]-N1-methyl-2-nitroethene-1,1-diamine  (EXP,ISO)
NADP zwitterion  (EXP)
NADP(+)  (EXP)
naled  (EXP,ISO)
naringin  (EXP)
Neferine  (EXP)
neostigmine  (ISO)
nevadensin  (EXP)
nickel atom  (EXP)
nicotine  (EXP)
nicotinic acid  (ISO)
O-acetyl-L-carnitine  (EXP)
O-methyleugenol  (ISO)
omethoate  (EXP,ISO)
organophosphorus compound  (ISO)
oxamyl  (EXP,ISO)
Oxotremorine  (ISO)
oxydemeton-methyl  (ISO)
pancuronium  (ISO)
paraoxon  (EXP,ISO)
Paraoxon-methyl  (EXP,ISO)
paraquat  (EXP,ISO)
parathion  (EXP,ISO)
parathion-methyl  (EXP,ISO)
PCB138  (EXP)
Pentoxifylline  (EXP)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
permethrin  (EXP)
phenobarbital  (EXP,ISO)
phenthoate  (ISO)
phenylmethanesulfonyl fluoride  (ISO)
phenytoin  (ISO)
phorate  (EXP,ISO)
phosmet  (EXP,ISO)
phosphamidon  (ISO)
phosphoryl trichloride  (ISO)
phoxim  (EXP)
physostigmine  (EXP,ISO)
physostigmine salicylate  (ISO)
phytoestrogen  (ISO)
piperazines  (EXP)
piperidine  (ISO)
Piracetam  (ISO)
pirimicarb  (ISO)
pirimiphos-methyl  (ISO)
pirinixic acid  (ISO)
potassium dichromate  (ISO)
pralidoxime  (EXP,ISO)
proanthocyanidin  (ISO)
prochlorperazine  (ISO)
profenofos  (EXP,ISO)
propamocarb  (ISO)
propiconazole  (EXP)
propidium  (ISO)
propoxur  (EXP,ISO)
puerarin  (ISO)
Pyridostigmine bromide  (EXP,ISO)
pyrimidines  (ISO)
quercetin  (EXP)
quercetin 3-O-beta-D-galactopyranoside  (EXP)
ranitidine  (EXP,ISO)
reserpine  (EXP)
resveratrol  (EXP,ISO)
rivastigmine  (EXP,ISO)
rotenone  (EXP,ISO)
sarin  (EXP,ISO)
scopolamine  (EXP,ISO)
selenium atom  (EXP)
serotonin  (ISO)
silicon atom  (EXP)
sodium arsenite  (EXP,ISO)
sodium fluoride  (EXP,ISO)
sodium nitrite  (ISO)
Soman  (EXP,ISO)
staurosporine  (ISO)
stevioside  (EXP)
streptozocin  (EXP,ISO)
tacrine  (EXP,ISO)
taurine  (EXP)
Tellimagrandin I  (ISO)
telmisartan  (ISO)
terbufos  (EXP,ISO)
tert-butyl hydroperoxide  (EXP)
tetrachlorohydroquinone  (ISO)
tetrachloromethane  (EXP)
tetrachlorvinphos  (ISO)
tetraethyllead  (EXP)
tetramethylpyrazine  (EXP)
thiacloprid  (EXP,ISO)
thiazolidines  (ISO)
Thiobencarb  (EXP)
thiodicarb  (EXP,ISO)
thioflavine T  (ISO)
thymoquinone  (EXP)
Tiapamil  (ISO)
tilorone  (ISO)
titanium dioxide  (ISO)
toluene  (ISO)
trandolapril  (EXP)
trans-caffeic acid  (EXP)
triazoles  (ISO)
tribufos  (ISO)
tributyl phosphate  (EXP)
trichlorfon  (EXP,ISO)
trichloroacetaldehyde  (ISO)
trifluoperazine  (EXP,ISO)
triptonide  (ISO)
tropan-3alpha-yl 3-hydroxy-2-phenylpropanoate  (EXP,ISO)
tubocurarine  (ISO)
valproic acid  (ISO)
vancomycin  (EXP)
vincristine  (EXP)
vitamin E  (EXP,ISO)
VX nerve agent  (EXP,ISO)
xaliproden  (EXP)
zinc atom  (EXP)
zinc dichloride  (EXP)
zinc(0)  (EXP)
zineb  (EXP)
zingerone  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References

References - curated
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2. Anuradha H, etal., Pharm Biol. 2010 May;48(5):499-503.
3. Bajgar J Acta Medica (Hradec Kralove). 2008;51(4):223-8.
4. Balakrishnan S, etal., Eur J Pharmacol. 2009 Feb 5.
5. Basu PS, etal., Clin Chim Acta. 1995 Feb 28;235(1):107-12.
6. Ben Assayag E, etal., Mol Med. 2010 Jul-Aug;16(7-8):278-86. doi: 10.2119/molmed.2010.00015. Epub 2010 Apr 14.
7. Berg RM, etal., Scand J Clin Lab Invest. 2011 Jul;71(4):350-2. doi: 10.3109/00365513.2011.558107. Epub 2011 Feb 8.
8. Blotnick E and Anglister L, Neuroscience. 2016 Apr 5;319:221-32. doi: 10.1016/j.neuroscience.2016.01.044. Epub 2016 Jan 25.
9. Chacon MA, etal., J Neurochem 2003 Oct;87(1):195-204.
10. Chan RY, etal., Proc Natl Acad Sci U S A 1999 Apr 13;96(8):4627-32.
11. Chowdhary S, etal., Clin Chim Acta. 2014 Apr 20;431C:66-76. doi: 10.1016/j.cca.2014.01.024. Epub 2014 Feb 7.
12. Chumakova OV and Liopo AV, Alcohol Alcohol. 1996 Mar;31(2):217-20.
13. da Silva CB, etal., J Med Microbiol. 2012 Feb;61(Pt 2):278-84. doi: 10.1099/jmm.0.035501-0. Epub 2011 Sep 15.
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15. Deschenes-Furry J, etal., J Biol Chem 2003 Feb 21;278(8):5710-7. Epub 2002 Dec 4.
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17. Feng G, etal., J Cell Biol 1999 Mar 22;144(6):1349-60.
18. Flumerfelt BA and Lewis PR, J Anat. 1975 Apr;119(Pt 2):309-31.
19. GOA data from the GO Consortium
20. Godfrey DA and Matschinsky FM, J Histochem Cytochem. 1975 Sep;23(9):645-51.
21. Juel VC and Massey JM, Orphanet J Rare Dis. 2007 Nov 6;2:44.
22. KEGG
23. Kousba AA, etal., Toxicol Sci. 2007 Jan;95(1):147-55. Epub 2006 Oct 3.
24. Legay C, etal., FEBS Lett 1993 Jan 4;315(2):163-6.
25. Legay C, etal., J Neurochem 1993 Jan;60(1):337-46.
26. McCorry LK Am J Pharm Educ. 2007 Aug 15;71(4):78.
27. MGD data from the GO Consortium
28. Money TT, etal., CNS Neurol Disord Drug Targets. 2010 Apr;9(2):241-56.
29. NCBI rat LocusLink and RefSeq merged data July 26, 2002
30. Ofek K, etal., J Mol Med (Berl). 2007 Nov;85(11):1239-51. Epub 2007 Jul 27.
31. Olivera S, etal., Mol Cell Neurosci 2003 May;23(1):96-106.
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34. Pipeline to import KEGG annotations from KEGG into RGD
35. Pipeline to import SMPDB annotations from SMPDB into RGD
36. RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
37. RGD automated import pipeline for gene-chemical interactions
38. RGD, Sept. 2003
39. Ross CD and Godfrey DA, J Histochem Cytochem. 1985 Jul;33(7):631-41.
40. Ross CD, etal., J Histochem Cytochem. 1983 Jul;31(7):927-37.
41. Ruberg M, etal., J Neurol Neurosurg Psychiatry. 1987 May;50(5):538-43.
42. Santoro A, etal., CNS Drugs. 2010 Feb 1;24(2):163-76. doi: 10.2165/11310960-000000000-00000.
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44. Schmatz R, etal., Eur J Pharmacol. 2009 May 21;610(1-3):42-8. Epub 2009 Mar 19.
45. Sembulingam K, etal., Indian J Med Sci. 2003 Nov;57(11):487-92.
46. Shih TM, etal., Arch Toxicol. 2006 Apr 21;.
47. Shimada H, etal., Neurology. 2009 Jul 28;73(4):273-8. Epub 2009 May 27.
48. Skopichev VG, etal., Morfologiia 2000;118(4):66-9.
49. Suhail M and Rizvi SI, Biochem J. 1989 May 1;259(3):897-9.
50. Sun M, etal., J Physiol. 2007 Feb 1;578(Pt 3):751-64. doi: 10.1113/jphysiol.2006.120147. Epub 2006 Oct 12.
51. Thullbery MD, etal., J Cell Biochem. 2005 Oct 15;96(3):599-610.
52. Wahba ZZ, etal., Exp Clin Endocrinol. 1992;99(1):26-30.
53. Winblad B, etal., Lancet. 2006 Apr 1;367(9516):1057-65.
54. Yin H, etal., Pediatr Dev Pathol. 2011 Oct 12.
55. Zarros A, etal., Metab Brain Dis. 2009 Jun;24(2):337-48. Epub 2009 Mar 19.
56. Zhou J, etal., Neurosci Lett. 2001 Jun 22;306(1-2):53-6.
Additional References at PubMed
PMID:1517212   PMID:3954986   PMID:7512968   PMID:7885444   PMID:8349597   PMID:8460160   PMID:8626792   PMID:10995443   PMID:12477932   PMID:12524166   PMID:12533614   PMID:12736766  
PMID:14645660   PMID:14678761   PMID:14766237   PMID:15454088   PMID:15474030   PMID:15488307   PMID:15526038   PMID:15579149   PMID:15869839   PMID:16262697   PMID:16270756   PMID:16429571  
PMID:16434405   PMID:16678265   PMID:16773467   PMID:16871442   PMID:17165152   PMID:17280650   PMID:17484629   PMID:17580119   PMID:17606622   PMID:17948252   PMID:18256932   PMID:18341513  
PMID:18406032   PMID:18437545   PMID:18980714   PMID:19049969   PMID:19378919   PMID:19411116   PMID:19490106   PMID:19680821   PMID:20153305   PMID:20399201   PMID:20450904   PMID:20599604  
PMID:20832780   PMID:21571001   PMID:21881966   PMID:22028090   PMID:22328136   PMID:22922167   PMID:22982053   PMID:23046746   PMID:23117006   PMID:23119107   PMID:24010172   PMID:24039284  
PMID:24517892   PMID:24590316   PMID:24632022   PMID:25711085   PMID:26948151   PMID:27019979   PMID:27694000   PMID:28849127   PMID:28916328  


Genomics

Comparative Map Data
Ache
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21219,407,359 - 19,413,713 (-)NCBI
Rnor_6.0 Ensembl1222,472,358 - 22,478,753 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01222,472,358 - 22,477,052 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01224,487,632 - 24,491,360 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1221,207,976 - 21,212,604 (-)NCBICelera
Cytogenetic Map12q12NCBI
ACHE
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl7100,889,994 - 100,896,974 (-)EnsemblGRCh38hg38GRCh38
GRCh387100,889,994 - 100,896,994 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh377100,487,615 - 100,494,614 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 367100,325,551 - 100,331,477 (-)NCBINCBI36hg18NCBI36
Build 347100,132,268 - 100,138,147NCBI
Celera795,218,191 - 95,224,120 (-)NCBI
Cytogenetic Map7q22.1NCBI
HuRef795,117,968 - 95,123,900 (-)NCBIHuRef
CHM1_17100,418,205 - 100,424,133 (-)NCBICHM1_1
CRA_TCAGchr7v2799,847,220 - 99,853,146 (-)NCBI
Ache
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395137,286,516 - 137,292,728 (+)NCBIGRCm39mm39
GRCm39 Ensembl5137,285,781 - 137,292,728 (+)Ensembl
GRCm385137,288,247 - 137,294,466 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5137,287,519 - 137,294,466 (+)EnsemblGRCm38mm10GRCm38
MGSCv375137,729,505 - 137,735,691 (+)NCBIGRCm37mm9NCBIm37
MGSCv365137,518,065 - 137,524,251 (+)NCBImm8
Celera5134,271,243 - 134,277,456 (+)NCBICelera
Cytogenetic Map5G2NCBI
cM Map576.32NCBI
Ache
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495557380,298 - 85,799 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495557379,606 - 85,799 (+)NCBIChiLan1.0ChiLan1.0
ACHE
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.17106,311,944 - 106,318,190 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7106,311,944 - 106,318,184 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0792,915,065 - 92,922,079 (-)NCBIMhudiblu_PPA_v0panPan3
ACHE
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.168,874,747 - 8,879,926 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl68,873,584 - 8,879,702 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha610,580,127 - 10,585,994 (+)NCBI
ROS_Cfam_1.068,809,869 - 8,815,742 (+)NCBI
UMICH_Zoey_3.168,661,436 - 8,668,230 (+)NCBI
UNSW_CanFamBas_1.068,640,504 - 8,646,368 (+)NCBI
UU_Cfam_GSD_1.068,822,240 - 8,828,117 (+)NCBI
Ache
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344133,174,520 - 133,179,854 (+)NCBI
SpeTri2.0NW_004936543856,678 - 862,080 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ACHE
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl38,732,324 - 8,739,149 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.138,732,451 - 8,738,274 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.238,159,377 - 8,165,197 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ACHE
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12812,328,304 - 12,335,302 (+)NCBI
ChlSab1.1 Ensembl2812,331,039 - 12,335,076 (+)Ensembl
Vero_WHO_p1.0NW_0236660703,993,802 - 4,000,839 (-)NCBI
Ache
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474016,275,108 - 16,280,639 (+)NCBI

Position Markers
D12Wox27  
Rat AssemblyChrPosition (strand)SourceJBrowse
Celera1221,213,565 - 21,213,775UniSTS
RH130210  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21219,407,423 - 19,407,618 (+)MAPPER
Rnor_6.01222,472,422 - 22,472,616NCBIRnor6.0
Rnor_5.01224,487,696 - 24,487,890UniSTSRnor5.0
Celera1221,208,040 - 21,208,234UniSTS
UniSTS:463940  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21219,410,275 - 19,410,579 (+)MAPPER
Rnor_6.01222,475,317 - 22,475,620NCBIRnor6.0
Rnor_5.01224,489,625 - 24,489,928UniSTSRnor5.0
Celera1221,210,869 - 21,211,172UniSTS
Ache  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21219,410,122 - 19,411,412 (+)MAPPER
Rnor_6.01222,475,164 - 22,476,453NCBIRnor6.0
Rnor_5.01224,489,472 - 24,490,761UniSTSRnor5.0
Celera1221,210,716 - 21,212,005UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2312418Kidm41Kidney mass QTL 413.70.0001kidney mass (VT:0002707)single kidney wet weight to body weight ratio (CMO:0000622)12122650917Rat
10450854Stl34Serum triglyceride level QTL 343.50.05blood LDL triglyceride amount (VT:0010699)blood lipoprotein triglyceride level (CMO:0002685)12122853017Rat
10755457Coatc14Coat color QTL 140.01759coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)12123035872Rat
6893681Bw109Body weight QTL 1092.30.004body mass (VT:0001259)body weight (CMO:0000012)12123758197Rat
1581516Cm56Cardiac mass QTL 564.20.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)12130749723Rat
1598855Bp294Blood pressure QTL 2943.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)12136919844Rat
7387292Kidm42Kidney mass QTL 423.030.0004kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)12138334225Rat
9590086Insglur6Insulin/glucose ratio QTL 618.970.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)1215081045150810Rat
9590147Scort7Serum corticosterone level QTL 713.610.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)1215081045150810Rat
7411545Bw128Body weight QTL 1285.20.001body mass (VT:0001259)body weight gain (CMO:0000420)1215081045150810Rat
7411586Foco5Food consumption QTL 55.40.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)1215081045150810Rat
7411660Foco28Food consumption QTL 2810.90.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)1215081045150810Rat
7411595Foco9Food consumption QTL 940.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)1215081045150810Rat
8694179Bw150Body weight QTL 1502.90.001body mass (VT:0001259)body weight gain (CMO:0000420)1215081045150810Rat
2303575Insul14Insulin level QTL 144blood insulin amount (VT:0001560)blood insulin level (CMO:0000349)1249257845492578Rat
737979Pia22Pristane induced arthritis QTL 2253.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)12247568747475687Rat
634351Apr5Acute phase response QTL 56.7blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)12251344247513442Rat
2302042Pia38Pristane induced arthritis QTL 383.50.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)12251344247513442Rat
634350Apr4Acute phase response QTL 46orosomucoid 1 amount (VT:0010541)plasma orosomucoid 1 level (CMO:0001467)12421005149210051Rat
1302792Scl21Serum cholesterol level QTL 213.80.0011blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)12895459327911196Rat
7411547Bw129Body weight QTL 1290.001body mass (VT:0001259)body weight gain (CMO:0000420)6922362652716770Rat
7411588Foco6Food consumption QTL 60.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12922362652716770Rat
7411597Foco10Food consumption QTL 100.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12922362652716770Rat
7411641Foco19Food consumption QTL 1927.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12922362652716770Rat
8552918Pigfal7Plasma insulin-like growth factor 1 level QTL 7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12922362652716770Rat
8552964Pigfal17Plasma insulin-like growth factor 1 level QTL 173.5blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12922362652716770Rat
8552912Pigfal6Plasma insulin-like growth factor 1 level QTL 65blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12922363052716770Rat
10059594Kidm46Kidney mass QTL 463.790.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)12978983452716770Rat
2293086Iddm30Insulin dependent diabetes mellitus QTL 303.82blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)121017588931975590Rat
61331Eau2Experimental allergic uveoretinitis QTL 20.0005uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)121025689031723732Rat
1300157Rf21Renal function QTL 214.4renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)121176499537522089Rat
1331786Kidm11Kidney mass QTL 113.571kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)121312721127285590Rat
1331755Bp219Blood pressure QTL 2193.041arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)121312721131723688Rat
1331761Bp218Blood pressure QTL 2182.973arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)121312721150320041Rat
61404Bw120Body weight QTL 1205.1body mass (VT:0001259)body mass index (BMI) (CMO:0000105)121441977552716770Rat
1549829Scl48Serum cholesterol level QTL 485blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)121502198652716770Rat
61416Pia4Pristane induced arthritis QTL 48.4joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)121571460935964508Rat
61421Cia12Collagen induced arthritis QTL 124.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)121571460941291738Rat
2300186Bmd59Bone mineral density QTL 597.10.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)121590890052716770Rat
2293699Bss49Bone structure and strength QTL 495.610.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra trabecular cross-sectional area (CMO:0001692)121590890052716770Rat
61443Btemp2Thermal response to stress QTL 23.30.000094body temperature trait (VT:0005535)core body temperature (CMO:0001036)121711477023839390Rat
631543Bp83Blood pressure QTL 835.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)121718558044098244Rat
2293684Bmd26Bone mineral density QTL 264.40.0002femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)121796086538409001Rat
1641928Alcrsp5Alcohol response QTL 5response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)121834247752716770Rat
2303569Gluco44Glucose level QTL 442blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)121834247752716770Rat
2302060Pia37Pristane induced arthritis QTL 376.10.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)121872904352716770Rat
1549902Bp269Blood pressure QTL 269arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)121875259352716770Rat
1549912Bp268Blood pressure QTL 268arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)101875259352716770Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:50
Count of miRNA genes:47
Interacting mature miRNAs:49
Transcripts:ENSRNOT00000075504
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 1 7 6 4 6 4 7 46 4
Low 2 43 50 35 15 35 4 4 28 35 41 11 4
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_172009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039089837 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039089838 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039089839 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039089841 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039089842 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039089843 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AF134349 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY555735 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC094521 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473973 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GQ338831 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GQ338832 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000227 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT531403 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT531408 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT531409 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  S50879 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X70140 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X70141 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X71089 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000075504   ⟹   ENSRNOP00000064185
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1222,472,578 - 22,477,052 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000086915   ⟹   ENSRNOP00000072252
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1222,473,963 - 22,478,753 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000089392   ⟹   ENSRNOP00000073951
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1222,472,358 - 22,478,752 (-)Ensembl
RefSeq Acc Id: NM_172009   ⟹   NP_742006
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21219,407,360 - 19,412,011 (-)NCBI
Rnor_6.01222,472,358 - 22,477,052 (-)NCBI
Rnor_5.01224,487,632 - 24,491,360 (-)NCBI
Celera1221,207,976 - 21,212,604 (-)RGD
Sequence:
RefSeq Acc Id: XM_039089837   ⟹   XP_038945765
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21219,407,359 - 19,413,710 (-)NCBI
RefSeq Acc Id: XM_039089838   ⟹   XP_038945766
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21219,407,359 - 19,413,713 (-)NCBI
RefSeq Acc Id: XM_039089839   ⟹   XP_038945767
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21219,407,359 - 19,413,713 (-)NCBI
RefSeq Acc Id: XM_039089841   ⟹   XP_038945769
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21219,410,564 - 19,413,699 (-)NCBI
RefSeq Acc Id: XM_039089842   ⟹   XP_038945770
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21219,407,359 - 19,411,202 (-)NCBI
RefSeq Acc Id: XM_039089843   ⟹   XP_038945771
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21219,407,359 - 19,413,713 (-)NCBI
Reference Sequences
RefSeq Acc Id: NP_742006   ⟸   NM_172009
- Peptide Label: precursor
- Sequence:
RefSeq Acc Id: ENSRNOP00000064185   ⟸   ENSRNOT00000075504
RefSeq Acc Id: ENSRNOP00000073951   ⟸   ENSRNOT00000089392
RefSeq Acc Id: ENSRNOP00000072252   ⟸   ENSRNOT00000086915
RefSeq Acc Id: XP_038945771   ⟸   XM_039089843
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038945767   ⟸   XM_039089839
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038945766   ⟸   XM_039089838
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038945765   ⟸   XM_039089837
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038945770   ⟸   XM_039089842
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038945769   ⟸   XM_039089841
- Peptide Label: isoform X3
Protein Domains
AChE_tetra   COesterase

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698534
Promoter ID:EPDNEW_R9048
Type:single initiation site
Name:Ache_1
Description:acetylcholinesterase
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01222,478,766 - 22,478,826EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:69313 AgrOrtholog
Ensembl Genes ENSRNOG00000050841 Ensembl, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000064185 UniProtKB/TrEMBL
  ENSRNOP00000072252 UniProtKB/TrEMBL
  ENSRNOP00000073951 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000075504 UniProtKB/TrEMBL
  ENSRNOT00000086915 UniProtKB/TrEMBL