Gene: Gpc2 (glypican 2) Rattus norvegicus
Analyze
Symbol:
Gpc2
Name:
glypican 2
RGD ID:
621363
Description:
Involved in neuron differentiation; positive regulation of neuron projection development; and smoothened signaling pathway. Predicted to be located in endoplasmic reticulum. Predicted to be active in cell surface and synapse. Orthologous to human GPC2 (glypican 2); PARTICIPATES IN Hedgehog signaling pathway; glypican signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,2',5,5'-tetrachlorobiphenyl.
Type:
protein-coding
RefSeq Status:
PROVISIONAL
Previously known as:
cerebroglycan; glypican 2 (cerebroglycan); glypican-2; HSPG M13
RGD Orthologs
Alliance Orthologs
More Info
more info ...
More Info
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Homo sapiens (human):
GPC2 (glypican 2)
HGNC
EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):
Gpc2 (glypican 2 cerebroglycan)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):
Gpc2 (glypican 2)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):
GPC2 (glypican 2)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Canis lupus familiaris (dog):
GPC2 (glypican 2)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
Gpc2 (glypican 2)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Sus scrofa (pig):
GPC2 (glypican 2)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):
GPC2 (glypican 2)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):
Gpc2 (glypican 2)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Other homologs 2
Homo sapiens (human):
CCL25 (C-C motif chemokine ligand 25)
HGNC
OMA
Alliance orthologs 3
Homo sapiens (human):
GPC2 (glypican 2)
Alliance
DIOPT (Ensembl Compara|HGNC|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Mus musculus (house mouse):
Gpc2 (glypican 2 cerebroglycan)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Danio rerio (zebrafish):
gpc2 (glypican 2)
Alliance
DIOPT (Ensembl Compara|OrthoFinder|PANTHER|PhylomeDB)
Danio rerio (zebrafish):
gpc2 (glypican 2)
Alliance
DIOPT (Ensembl Compara|OrthoFinder|PhylomeDB)
Caenorhabditis elegans (roundworm):
gpn-1
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Caenorhabditis elegans (roundworm):
gpn-1
Alliance
DIOPT (Ensembl Compara|InParanoid|OMA|OrthoFinder|OrthoInspector|PhylomeDB|SonicParanoid)
Drosophila melanogaster (fruit fly):
dlp
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Drosophila melanogaster (fruit fly):
dlp
Alliance
DIOPT (Ensembl Compara|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):
gpc2
Alliance
DIOPT (Ensembl Compara|OrthoFinder|PANTHER|PhylomeDB)
Latest Assembly:
GRCr8 - GRCr8 Assembly
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 12 22,391,489 - 22,397,822 (-) NCBI GRCr8 GRCr8 GRCr8 GRCr8 Ensembl 12 22,391,489 - 22,397,822 (-) Ensembl GRCr8 mRatBN7.2 12 17,277,875 - 17,284,297 (-) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 12 17,277,875 - 17,284,208 (-) Ensembl mRatBN7.2 UTH_Rnor_SHR_Utx 12 18,244,924 - 18,251,250 (-) NCBI UTH_Rnor_SHR_Utx UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 12 18,868,646 - 18,874,972 (-) NCBI UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 12 17,922,063 - 17,928,389 (-) NCBI UTH_Rnor_WKY_Bbb_1.0 UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 12 19,593,041 - 19,599,374 (-) NCBI Rnor_6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 12 19,593,041 - 19,599,374 (-) Ensembl rn6 Rnor6.0 Rnor_5.0 12 21,649,636 - 21,655,969 (-) NCBI Rnor_5.0 Rnor_5.0 rn5 RGSC_v3.4 12 17,858,354 - 17,864,687 (-) NCBI RGSC_v3.4 RGSC_v3.4 rn4 Celera 12 19,202,336 - 19,208,665 (-) NCBI Celera RGSC_v3.1 12 17,847,875 - 17,854,209 (-) NCBI Cytogenetic Map 12 q11 NCBI
JBrowse:
Imported Disease Annotations - ClinVar
Only show annotations with direct experimental evidence (0 objects hidden)
Gpc2 Rat 1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene multiple interactions ISO Gpc2 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Gpc2 Rat 17alpha-ethynylestradiol affects expression EXP 6480464 Ethinyl Estradiol affects the expression of GPC2 mRNA CTD PMID:15212814 Gpc2 Rat 17beta-estradiol multiple interactions ISO GPC2 (Homo sapiens) 6480464 [Estradiol co-treated with TGFB1 protein] results in increased expression of GPC2 mRNA CTD PMID:30165855 Gpc2 Rat 17beta-estradiol multiple interactions EXP 6480464 [Testosterone co-treated with Estradiol] results in increased expression of GPC2 mRNA CTD PMID:32741896 Gpc2 Rat 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO Gpc2 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Gpc2 Rat 2,2',5,5'-tetrachlorobiphenyl increases expression EXP 6480464 2,5,2',5'-tetrachlorobiphenyl results in increased expression of GPC2 mRNA CTD PMID:23829299 Gpc2 Rat 2,2',5,5'-tetrachlorobiphenyl multiple interactions ISO Gpc2 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Gpc2 Rat 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of GPC2 mRNA CTD PMID:19490992|PMID:33387578 Gpc2 Rat 2,4,4'-trichlorobiphenyl multiple interactions ISO Gpc2 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Gpc2 Rat 4,4'-sulfonyldiphenol decreases methylation ISO Gpc2 (Mus musculus) 6480464 bisphenol S results in decreased methylation of GPC2 exon CTD PMID:33297965 Gpc2 Rat 4,4'-sulfonyldiphenol affects methylation ISO Gpc2 (Mus musculus) 6480464 bisphenol S affects the methylation of GPC2 gene CTD PMID:31683443 Gpc2 Rat 6-propyl-2-thiouracil increases expression EXP 6480464 Propylthiouracil results in increased expression of GPC2 mRNA CTD PMID:24780913 Gpc2 Rat acetamide increases expression EXP 6480464 acetamide results in increased expression of GPC2 mRNA CTD PMID:31881176 Gpc2 Rat acrylamide decreases expression EXP 6480464 Acrylamide results in decreased expression of GPC2 mRNA CTD PMID:28959563 Gpc2 Rat acrylamide decreases expression ISO GPC2 (Homo sapiens) 6480464 Acrylamide results in decreased expression of GPC2 mRNA CTD PMID:32763439 Gpc2 Rat ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of GPC2 mRNA CTD PMID:16483693 Gpc2 Rat atrazine increases expression ISO GPC2 (Homo sapiens) 6480464 Atrazine results in increased expression of GPC2 mRNA CTD PMID:22378314 Gpc2 Rat benzo[a]pyrene increases expression ISO GPC2 (Homo sapiens) 6480464 Benzo(a)pyrene results in increased expression of GPC2 mRNA CTD PMID:32234424 Gpc2 Rat bis(2-ethylhexyl) phthalate increases expression ISO Gpc2 (Mus musculus) 6480464 Diethylhexyl Phthalate results in increased expression of GPC2 mRNA CTD PMID:28085963 Gpc2 Rat bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of GPC2 mRNA CTD PMID:25181051 Gpc2 Rat bisphenol A decreases expression ISO Gpc2 (Mus musculus) 6480464 bisphenol A results in decreased expression of GPC2 mRNA CTD PMID:32156529 Gpc2 Rat bisphenol A increases methylation ISO Gpc2 (Mus musculus) 6480464 bisphenol A results in increased methylation of GPC2 promoter CTD PMID:27312807 Gpc2 Rat butanal increases expression ISO GPC2 (Homo sapiens) 6480464 butyraldehyde results in increased expression of GPC2 mRNA CTD PMID:26079696 Gpc2 Rat cadmium atom multiple interactions ISO GPC2 (Homo sapiens) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of GPC2 more ... CTD PMID:35301059 Gpc2 Rat cadmium dichloride multiple interactions ISO GPC2 (Homo sapiens) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of GPC2 more ... CTD PMID:35301059 Gpc2 Rat CGP 52608 multiple interactions ISO GPC2 (Homo sapiens) 6480464 CGP 52608 promotes the reaction [RORA protein binds to GPC2 gene] CTD PMID:28238834 Gpc2 Rat Cuprizon decreases expression EXP 6480464 Cuprizone results in decreased expression of GPC2 mRNA CTD PMID:26577399 Gpc2 Rat dexamethasone decreases expression ISO GPC2 (Homo sapiens) 6480464 Dexamethasone results in decreased expression of GPC2 mRNA CTD PMID:25047013 Gpc2 Rat dorsomorphin multiple interactions ISO GPC2 (Homo sapiens) 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... CTD PMID:27188386 Gpc2 Rat exemestane increases expression ISO GPC2 (Homo sapiens) 6480464 exemestane results in increased expression of GPC2 mRNA CTD PMID:17254854 Gpc2 Rat folic acid decreases expression ISO Gpc2 (Mus musculus) 6480464 Folic Acid results in decreased expression of GPC2 mRNA CTD PMID:25629700 Gpc2 Rat glycidol decreases expression EXP 6480464 glycidol results in decreased expression of GPC2 mRNA CTD PMID:24915197 Gpc2 Rat monosodium L-glutamate increases expression EXP 6480464 Sodium Glutamate results in increased expression of GPC2 mRNA CTD PMID:20928830 Gpc2 Rat niclosamide increases expression ISO GPC2 (Homo sapiens) 6480464 Niclosamide results in increased expression of GPC2 mRNA CTD PMID:36318118 Gpc2 Rat O-methyleugenol increases expression ISO GPC2 (Homo sapiens) 6480464 methyleugenol results in increased expression of GPC2 mRNA CTD PMID:32234424 Gpc2 Rat okadaic acid increases expression ISO GPC2 (Homo sapiens) 6480464 Okadaic Acid results in increased expression of GPC2 mRNA CTD PMID:38832940 Gpc2 Rat ozone multiple interactions ISO GPC2 (Homo sapiens) 6480464 [Air Pollutants results in increased abundance of Ozone] which affects the expression of GPC2 mRNA CTD PMID:35430440 Gpc2 Rat paracetamol increases expression ISO GPC2 (Homo sapiens) 6480464 Acetaminophen results in increased expression of GPC2 mRNA CTD PMID:29067470 Gpc2 Rat paracetamol increases expression EXP 6480464 Acetaminophen results in increased expression of GPC2 mRNA CTD PMID:33387578 Gpc2 Rat paraquat decreases expression EXP 6480464 Paraquat results in decreased expression of GPC2 mRNA CTD PMID:32680482 Gpc2 Rat PCB138 multiple interactions ISO Gpc2 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Gpc2 Rat PCB138 decreases expression EXP 6480464 2,2',3',4,4',5-hexachlorobiphenyl results in decreased expression of GPC2 mRNA CTD PMID:23829299 Gpc2 Rat pentanal increases expression ISO GPC2 (Homo sapiens) 6480464 pentanal results in increased expression of GPC2 mRNA CTD PMID:26079696 Gpc2 Rat phenylmercury acetate multiple interactions ISO GPC2 (Homo sapiens) 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... CTD PMID:27188386 Gpc2 Rat SB 431542 multiple interactions ISO GPC2 (Homo sapiens) 6480464 [LDN 193189 co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with FGF2 protein] results in increased expression of GPC2 more ... CTD PMID:27188386|PMID:37664457 Gpc2 Rat sodium arsenite increases expression ISO GPC2 (Homo sapiens) 6480464 sodium arsenite results in increased expression of GPC2 mRNA CTD PMID:38568856 Gpc2 Rat sunitinib decreases expression ISO GPC2 (Homo sapiens) 6480464 Sunitinib results in decreased expression of GPC2 mRNA CTD PMID:31533062 Gpc2 Rat testosterone multiple interactions EXP 6480464 [Testosterone co-treated with Estradiol] results in increased expression of GPC2 mRNA CTD PMID:32741896 Gpc2 Rat titanium dioxide decreases expression ISO Gpc2 (Mus musculus) 6480464 titanium dioxide results in decreased expression of GPC2 mRNA CTD PMID:29264374 Gpc2 Rat titanium dioxide decreases methylation ISO Gpc2 (Mus musculus) 6480464 titanium dioxide results in decreased methylation of GPC2 promoter alternative form CTD PMID:35295148 Gpc2 Rat trichloroethene decreases expression EXP 6480464 Trichloroethylene results in decreased expression of GPC2 mRNA CTD PMID:33387578 Gpc2 Rat trichostatin A affects expression ISO GPC2 (Homo sapiens) 6480464 trichostatin A affects the expression of GPC2 mRNA CTD PMID:28542535 Gpc2 Rat triphenyl phosphate affects expression ISO GPC2 (Homo sapiens) 6480464 triphenyl phosphate affects the expression of GPC2 mRNA CTD PMID:37042841 Gpc2 Rat tunicamycin decreases expression ISO GPC2 (Homo sapiens) 6480464 Tunicamycin results in decreased expression of GPC2 mRNA CTD PMID:22378314 Gpc2 Rat urethane decreases expression ISO GPC2 (Homo sapiens) 6480464 Urethane results in decreased expression of GPC2 mRNA CTD PMID:28818685 Gpc2 Rat valproic acid affects expression ISO GPC2 (Homo sapiens) 6480464 Valproic Acid affects the expression of GPC2 mRNA CTD PMID:25979313 Gpc2 Rat valproic acid decreases expression ISO GPC2 (Homo sapiens) 6480464 Valproic Acid results in decreased expression of GPC2 mRNA CTD PMID:23179753|PMID:24935251 Gpc2 Rat vorinostat decreases expression ISO GPC2 (Homo sapiens) 6480464 vorinostat results in decreased expression of GPC2 mRNA CTD PMID:27188386