Baz1b (bromodomain adjacent to zinc finger domain, 1B) - Rat Genome Database

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Gene: Baz1b (bromodomain adjacent to zinc finger domain, 1B) Rattus norvegicus
Analyze
Symbol: Baz1b
Name: bromodomain adjacent to zinc finger domain, 1B
RGD ID: 1597089
Description: Predicted to enable histone H2AXY142 kinase activity and histone binding activity. Predicted to be involved in several processes, including chromatin remodeling; negative regulation of mitotic chromosome condensation; and positive regulation of transcription by RNA polymerase III. Predicted to act upstream of or within chromatin organization. Predicted to be located in condensed chromosome; nuclear replication fork; and nucleoplasm. Predicted to be part of B-WICH complex; WICH complex; and pericentric heterochromatin. Orthologous to human BAZ1B (bromodomain adjacent to zinc finger domain 1B); PARTICIPATES IN ataxia telangiectasia-mutated (ATM) signaling pathway; ISWI family mediated chromatin remodeling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: bromodomain adjacent to zinc finger domain protein 1B; tyrosine-protein kinase BAZ1B
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81227,068,541 - 27,126,511 (-)NCBIGRCr8
mRatBN7.21221,431,985 - 21,489,956 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1221,431,985 - 21,490,426 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1222,573,589 - 22,631,630 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01223,185,918 - 23,243,954 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01222,252,394 - 22,310,416 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01224,478,882 - 24,536,851 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1224,478,898 - 24,537,313 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01226,476,185 - 26,534,154 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41222,586,411 - 22,644,378 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1223,194,558 - 23,252,515 (-)NCBICelera
Cytogenetic Map12q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-tribromophenol  (ISO)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
4-amino-2,6-dinitrotoluene  (EXP)
4-vinylcyclohexene dioxide  (ISO)
6-propyl-2-thiouracil  (EXP)
7,9-dihydro-1H-purine-2,6,8(3H)-trione  (ISO)
acetylsalicylic acid  (ISO)
aflatoxin B1  (ISO)
aristolochic acid A  (ISO)
atrazine  (ISO)
benzatropine  (ISO)
benzene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (EXP,ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
cannabidiol  (ISO)
choline  (ISO)
clofibrate  (ISO)
clozapine  (ISO)
cocaine  (ISO)
copper atom  (EXP)
copper(0)  (EXP)
coumarin  (ISO)
Cuprizon  (ISO)
decabromodiphenyl ether  (EXP,ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (EXP)
diethylstilbestrol  (EXP)
elemental selenium  (ISO)
enzyme inhibitor  (ISO)
epoxiconazole  (ISO)
fenvalerate  (EXP)
folic acid  (ISO)
FR900359  (ISO)
geraniol  (ISO)
ivermectin  (ISO)
L-methionine  (ISO)
methamphetamine  (ISO)
methoxychlor  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
phenethyl isothiocyanate  (EXP)
pirinixic acid  (ISO)
rotenone  (EXP)
selenium atom  (ISO)
sodium arsenite  (ISO)
Soman  (EXP)
streptozocin  (ISO)
sunitinib  (ISO)
tert-butyl hydroperoxide  (ISO)
tetrachloromethane  (EXP)
thapsigargin  (ISO)
thioacetamide  (EXP)
trichloroethene  (EXP,ISO)
trimellitic anhydride  (ISO)
triphenyl phosphate  (ISO)
tungsten  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
vitamin E  (ISO)
zinc sulfate  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. ATP-dependent chromatin remodeling: genetics, genomics and mechanisms. Hargreaves DC and Crabtree GR, Cell Res. 2011 Mar;21(3):396-420. doi: 10.1038/cr.2011.32. Epub 2011 Mar 1.
3. Push back to respond better: regulatory inhibition of the DNA double-strand break response. Panier S and Durocher D, Nat Rev Mol Cell Biol. 2013 Oct;14(10):661-72. doi: 10.1038/nrm3659. Epub 2013 Sep 4.
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:11980720   PMID:15543136   PMID:19092802   PMID:31505169  


Genomics

Comparative Map Data
Baz1b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81227,068,541 - 27,126,511 (-)NCBIGRCr8
mRatBN7.21221,431,985 - 21,489,956 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1221,431,985 - 21,490,426 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1222,573,589 - 22,631,630 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01223,185,918 - 23,243,954 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01222,252,394 - 22,310,416 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01224,478,882 - 24,536,851 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1224,478,898 - 24,537,313 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01226,476,185 - 26,534,154 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41222,586,411 - 22,644,378 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1223,194,558 - 23,252,515 (-)NCBICelera
Cytogenetic Map12q12NCBI
BAZ1B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38773,440,406 - 73,522,293 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl773,440,406 - 73,522,293 (-)EnsemblGRCh38hg38GRCh38
GRCh37772,854,736 - 72,936,623 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36772,492,676 - 72,574,544 (-)NCBINCBI36Build 36hg18NCBI36
Build 34772,299,383 - 72,381,200NCBI
Celera768,332,639 - 68,414,529 (-)NCBICelera
Cytogenetic Map7q11.23NCBI
HuRef768,736,057 - 68,818,392 (-)NCBIHuRef
CHM1_1773,000,196 - 73,082,038 (-)NCBICHM1_1
T2T-CHM13v2.0774,640,900 - 74,722,781 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2772,187,800 - 72,269,687 (-)NCBI
Baz1b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395135,214,094 - 135,274,985 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5135,216,118 - 135,274,983 (+)EnsemblGRCm39 Ensembl
GRCm385135,187,323 - 135,246,131 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5135,187,264 - 135,246,129 (+)EnsemblGRCm38mm10GRCm38
MGSCv375135,663,193 - 135,721,999 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365135,471,986 - 135,529,194 (+)NCBIMGSCv36mm8
Celera5132,199,039 - 132,257,800 (+)NCBICelera
Cytogenetic Map5G2NCBI
cM Map575.05NCBI
Baz1b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545614,185,107 - 14,240,688 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495545614,185,091 - 14,242,391 (+)NCBIChiLan1.0ChiLan1.0
BAZ1B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2691,379,549 - 91,461,458 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan17139,644,104 - 139,726,092 (+)NCBINHGRI_mPanPan1
PanPan1.1780,594,629 - 80,675,645 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl780,594,626 - 80,675,709 (-)Ensemblpanpan1.1panPan2
BAZ1B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.166,709,648 - 6,776,904 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl66,709,697 - 6,776,867 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha68,406,933 - 8,475,941 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.066,524,701 - 6,594,233 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl66,524,385 - 6,592,296 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.166,514,050 - 6,569,390 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.066,461,859 - 6,531,708 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.066,625,515 - 6,694,618 (+)NCBIUU_Cfam_GSD_1.0
Baz1b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344131,246,801 - 131,322,970 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365432,713,589 - 2,779,993 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365432,713,575 - 2,779,947 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BAZ1B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl310,761,499 - 10,843,840 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1310,761,461 - 10,843,918 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2310,460,760 - 10,543,482 (-)NCBISscrofa10.2Sscrofa10.2susScr3
BAZ1B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1289,533,802 - 9,617,164 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl289,534,114 - 9,617,190 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660706,855,992 - 6,938,041 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Baz1b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474014,248,274 - 14,319,823 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474014,247,972 - 14,319,713 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Baz1b
368 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:604
Count of miRNA genes:296
Interacting mature miRNAs:377
Transcripts:ENSRNOT00000001975
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631560Apr1Acute phase response QTL 16.1orosomucoid 1 amount (VT:0010541)plasma orosomucoid 1 level (CMO:0001467)121914436246669029Rat
8552964Pigfal17Plasma insulin-like growth factor 1 level QTL 173.5blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449546669029Rat
61324Eae5Experimental allergic encephalomyelitis QTL 514nervous system integrity trait (VT:0010566)percentage of study population developing relapsing-remitting experimental autoimmune encephalomyelitis during a period of time (CMO:0001402)121961087046669029Rat
9590147Scort7Serum corticosterone level QTL 713.610.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)12142110980Rat
1549829Scl48Serum cholesterol level QTL 485blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)12960327746669029Rat
61331Eau2Experimental allergic uveoretinitis QTL 20.0005uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)12852542328064601Rat
737822Alc10Alcohol consumption QTL 102.2consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)121961087040218516Rat
2293684Bmd26Bone mineral density QTL 264.40.0002femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)121587265332974238Rat
6893681Bw109Body weight QTL 1092.30.004body mass (VT:0001259)body weight (CMO:0000012)12123297788Rat
1302792Scl21Serum cholesterol level QTL 213.80.0011blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)12719673046669029Rat
1598855Bp294Blood pressure QTL 2943.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)12134851688Rat
10755457Coatc14Coat color QTL 140.01759coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)12122591684Rat
1331761Bp218Blood pressure QTL 2182.973arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)121107382545055165Rat
8694179Bw150Body weight QTL 1502.90.001body mass (VT:0001259)body weight gain (CMO:0000420)12142110980Rat
7411545Bw128Body weight QTL 1285.20.001body mass (VT:0001259)body weight gain (CMO:0000420)12142110980Rat
7411547Bw129Body weight QTL 1290.001body mass (VT:0001259)body weight gain (CMO:0000420)6556449546669029Rat
1300157Rf21Renal function QTL 214.4renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)12931821632103380Rat
737979Pia22Pristane induced arthritis QTL 2253.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)12144465750Rat
1298081Cia25Collagen induced arthritis QTL 254.7joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)121961088935682913Rat
2300186Bmd59Bone mineral density QTL 597.10.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)121047413746669029Rat
7411660Foco28Food consumption QTL 2810.90.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12142110980Rat
1331755Bp219Blood pressure QTL 2193.041arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)121107382528064557Rat
70213Niddm27Non-insulin dependent diabetes mellitus QTL 273.72blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)121983578938193007Rat
2306789Ean6Experimental allergic neuritis QTL 64.9nervous system integrity trait (VT:0010566)experimental autoimmune neuritis severity score (CMO:0001528)121961087024139202Rat
7411641Foco19Food consumption QTL 1927.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12556449546669029Rat
7411643Foco20Food consumption QTL 200.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)122032881946669029Rat
5684888Pia42Pristane induced arthritis QTL 42joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)121961087042828880Rat
1549912Bp268Blood pressure QTL 268arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)101318273646669029Rat
2302060Pia37Pristane induced arthritis QTL 376.10.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)121319815746669029Rat
1641928Alcrsp5Alcohol response QTL 5response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)121281238546669029Rat
8552912Pigfal6Plasma insulin-like growth factor 1 level QTL 65blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449846669029Rat
10059594Kidm46Kidney mass QTL 463.790.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)12610757946669029Rat
1581516Cm56Cardiac mass QTL 564.20.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)12129333307Rat
9590086Insglur6Insulin/glucose ratio QTL 618.970.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)12142110980Rat
8552918Pigfal7Plasma insulin-like growth factor 1 level QTL 7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449546669029Rat
1549902Bp269Blood pressure QTL 269arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)121318273646669029Rat
61404Bw120Body weight QTL 1205.1body mass (VT:0001259)body mass index (BMI) (CMO:0000105)121235161946669029Rat
1331786Kidm11Kidney mass QTL 113.571kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)121107382524234895Rat
2293699Bss49Bone structure and strength QTL 495.610.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra trabecular cross-sectional area (CMO:0001692)121047413746669029Rat
634351Apr5Acute phase response QTL 56.7blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)12144503507Rat
634350Apr4Acute phase response QTL 46orosomucoid 1 amount (VT:0010541)plasma orosomucoid 1 level (CMO:0001467)12117200546172005Rat
61416Pia4Pristane induced arthritis QTL 48.4joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)121363552330827399Rat
631521Pia12Pristane induced arthritis QTL 128.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)122025941723672083Rat
61421Cia12Collagen induced arthritis QTL 124.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)121363552335682913Rat
2303569Gluco44Glucose level QTL 442blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)121281238546669029Rat
7411586Foco5Food consumption QTL 55.40.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12142110980Rat
2303575Insul14Insulin level QTL 144blood insulin amount (VT:0001560)blood insulin level (CMO:0000349)12142450532Rat
7411588Foco6Food consumption QTL 60.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12556449546669029Rat
2302042Pia38Pristane induced arthritis QTL 383.50.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)12144503507Rat
7411595Foco9Food consumption QTL 940.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12142110980Rat
7411597Foco10Food consumption QTL 100.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12556449546669029Rat
2293086Iddm30Insulin dependent diabetes mellitus QTL 303.82blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)12844949028302290Rat
631543Bp83Blood pressure QTL 835.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)121555082638478808Rat

Markers in Region
BF388132  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21221,484,080 - 21,484,280 (+)MAPPERmRatBN7.2
Rnor_6.01224,530,977 - 24,531,176NCBIRnor6.0
Rnor_5.01226,528,280 - 26,528,479UniSTSRnor5.0
RGSC_v3.41222,638,504 - 22,638,703UniSTSRGSC3.4
Celera1223,246,641 - 23,246,840UniSTS
RH 3.4 Map12338.7UniSTS
Cytogenetic Map12q12UniSTS
Baz1b  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21221,489,816 - 21,489,937 (+)MAPPERmRatBN7.2
Rnor_6.01224,536,712 - 24,536,832NCBIRnor6.0
Rnor_5.01226,534,015 - 26,534,135UniSTSRnor5.0
RGSC_v3.41222,644,239 - 22,644,359UniSTSRGSC3.4
Celera1223,252,376 - 23,252,496UniSTS
Cytogenetic Map12q12UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 55 39 19 39 6 9 74 35 39 11 6
Low 2 2 2 2 2 2 2
Below cutoff

Sequence


Ensembl Acc Id: ENSRNOT00000001975   ⟹   ENSRNOP00000001975
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1221,431,985 - 21,490,426 (-)Ensembl
Rnor_6.0 Ensembl1224,478,898 - 24,537,313 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000100108   ⟹   ENSRNOP00000094596
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1221,431,985 - 21,489,956 (-)Ensembl
RefSeq Acc Id: NM_001191916   ⟹   NP_001178845
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81227,068,541 - 27,126,511 (-)NCBI
mRatBN7.21221,431,985 - 21,489,956 (-)NCBI
Rnor_6.01224,478,882 - 24,536,851 (-)NCBI
Rnor_5.01226,476,185 - 26,534,154 (-)NCBI
Celera1223,194,558 - 23,252,515 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039089653   ⟹   XP_038945581
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81227,068,543 - 27,101,282 (-)NCBI
mRatBN7.21221,431,987 - 21,464,719 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001178845 (Get FASTA)   NCBI Sequence Viewer  
  XP_038945581 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein ABB88408 (Get FASTA)   NCBI Sequence Viewer  
  ABB88409 (Get FASTA)   NCBI Sequence Viewer  
  EDM13381 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000001975.6
  ENSRNOP00000094596.1
RefSeq Acc Id: NP_001178845   ⟸   NM_001191916
- UniProtKB: G3V661 (UniProtKB/TrEMBL),   A0A8I6ALC2 (UniProtKB/TrEMBL),   A6J0E2 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000001975   ⟸   ENSRNOT00000001975
RefSeq Acc Id: XP_038945581   ⟸   XM_039089653
- Peptide Label: isoform X1
- UniProtKB: G3V661 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000094596   ⟸   ENSRNOT00000100108
Protein Domains
Bromo   DDT   PHD-type   RING-type   WAC

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-G3V661-F1-model_v2 AlphaFold G3V661 1-1476 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698556
Promoter ID:EPDNEW_R9081
Type:single initiation site
Name:Baz1b_1
Description:bromodomain adjacent to zinc finger domain, 1B
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01224,536,948 - 24,537,008EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1597089 AgrOrtholog
BioCyc Gene G2FUF-19611 BioCyc
Ensembl Genes ENSRNOG00000001453 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000001975.8 UniProtKB/TrEMBL
  ENSRNOT00000100108.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.920.10 UniProtKB/TrEMBL
  3.30.40.10 UniProtKB/TrEMBL
InterPro BAZ1B UniProtKB/TrEMBL
  BAZ1B_Bromo UniProtKB/TrEMBL
  BAZ1B_PHD UniProtKB/TrEMBL
  Bromodomain UniProtKB/TrEMBL
  Bromodomain-like_sf UniProtKB/TrEMBL
  Bromodomain_CS UniProtKB/TrEMBL
  DDT_dom_superfamily UniProtKB/TrEMBL
  WHIM1_dom UniProtKB/TrEMBL
  WHIM2_dom UniProtKB/TrEMBL
  WSTF_Acf1_Cbp146 UniProtKB/TrEMBL
  Zinc_finger_PHD-type_CS UniProtKB/TrEMBL
  Znf_FYVE_PHD UniProtKB/TrEMBL
  Znf_PHD UniProtKB/TrEMBL
  Znf_PHD-finger UniProtKB/TrEMBL
  Znf_RING UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
KEGG Report rno:368002 UniProtKB/TrEMBL
NCBI Gene 368002 ENTREZGENE
PANTHER TYROSINE-PROTEIN KINASE BAZ1B UniProtKB/TrEMBL
  TYROSINE-PROTEIN KINASE BAZ1B UniProtKB/TrEMBL
Pfam Bromodomain UniProtKB/TrEMBL
  PHD UniProtKB/TrEMBL
  WAC_Acf1_DNA_bd UniProtKB/TrEMBL
  WHIM1 UniProtKB/TrEMBL
  WHIM2 UniProtKB/TrEMBL
PhenoGen Baz1b PhenoGen
PRINTS BROMODOMAIN UniProtKB/TrEMBL
PROSITE BROMODOMAIN_1 UniProtKB/TrEMBL
  BROMODOMAIN_2 UniProtKB/TrEMBL
  DDT UniProtKB/TrEMBL
  WAC UniProtKB/TrEMBL
  ZF_PHD_1 UniProtKB/TrEMBL
  ZF_PHD_2 UniProtKB/TrEMBL
  ZF_RING_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000001453 RatGTEx
SMART BROMO UniProtKB/TrEMBL
  DDT UniProtKB/TrEMBL
  PHD UniProtKB/TrEMBL
Superfamily-SCOP Bromodomain UniProtKB/TrEMBL
  FYVE_PHD_ZnF UniProtKB/TrEMBL
UniProt A0A8I6ALC2 ENTREZGENE, UniProtKB/TrEMBL
  A6J0E2 ENTREZGENE, UniProtKB/TrEMBL
  G3V661 ENTREZGENE, UniProtKB/TrEMBL
  Q2V6G6_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-03-03 Baz1b  bromodomain adjacent to zinc finger domain, 1B  Baz1b  bromodomain adjacent to zinc finger domain protein 1B  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-11-20 Baz1b  bromodomain adjacent to zinc finger domain protein 1B      Symbol and Name status set to provisional 70820 PROVISIONAL