Bp294 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL Registration

QTL: Bp294 (Blood pressure QTL 294) Rattus norvegicus

Symbol: Bp294
Name: Blood pressure QTL 294
RGD ID: 1598855
Previously known as: BP-f3
Trait: arterial blood pressure trait   (VT:2000000)    
Measurement Type: systolic blood pressure   (CMO:0000004)    
LOD Score: 3.5
P Value: Not Available
Variance: Not Available
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2121 - 34,851,688RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.0121 - 36,919,844RGD_MAPPER_PIPELINERnor6.0
Rnor_5.0121 - 38,944,117RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.4121 - 35,270,263RGD_MAPPER_PIPELINERGSC3.4
RGSC_v3.1120 - 35,300,192RGD
Cross Type: intercross
Strains Crossed: SR/JrHsd SS/JrHsd 




  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bp294Rathypertension  IDA 1581737 RGD 

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bp294Ratincreased systemic arterial systolic blood pressure  IDA 1581737 RGD 

Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bp294Ratsystolic blood pressure  IDA 1581737 RGD 

Experimental Condition
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bp294Ratcontrolled sodium content diet  IDA 1581737 RGD 

Measurement Method
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bp294Ratintra-aortic abdominal radiotelemetry  IDA 1581737 RGD 

Rat Strain
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bp294RatSR/JrHsd  IEA 1581737 RGD 
Bp294RatSS/JrHsd  IEA 1581737 RGD 

Vertebrate Trait
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bp294Ratarterial blood pressure trait  IDA 1581737 RGD 


#
Reference Title
Reference Citation
1. Sex-specific QTLs and interacting loci underlie salt-sensitive hypertension and target organ complications in Dahl S/jrHS hypertensive rats. Herrera VL, etal., Physiol Genomics. 2006 Aug 16;26(3):172-9. Epub 2006 May 23.


1 to 20 of 826 rows
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
1591034Zar1lzygote arrest 1-like124653456434Rat
2219Brca2BRCA2, DNA repair associated1259492103789Rat
41278455LOC120096086U4 spliceosomal RNA127969379833Rat
1595713N4bp2l1NEDD4 binding protein 2-like 112102572128352Rat
1359603N4bp2l2NEDD4 binding protein 2-like 212137342200292Rat
1310838Pds5bPDS5 cohesin associated factor B12202481345596Rat
40996321LOC120096101U6 spliceosomal RNA12242483242588Rat
41260407LOC120096119small nucleolar RNA SNORA1712244785244876Rat
41300882LOC120095865uncharacterized LOC12009586512358049370593Rat
7689250LOC102548900uncharacterized LOC10254890012397693419407Rat
620396KlKlotho12490402531417Rat
7752935LOC102548964uncharacterized LOC10254896412536196556469Rat
1564816Stard13StAR-related lipid transfer domain containing 1312566282959372Rat
41260173Trnap-agg21transfer RNA proline (anticodon AGG) 2112640392640473Rat
7733180LOC102549089uncharacterized LOC10254908912874530895451Rat
1306832Rfc3replication factor C subunit 31210009871011778Rat
1626010Vom2r-ps97vomeronasal 2 receptor, pseudogene 971210194521019856Rat
7657613LOC102554571uncharacterized LOC1025545711210274001034088Rat
41130581LOC1200960765S ribosomal RNA1210444051044522Rat
41104179LOC1200960255S ribosomal RNA1210467881046905Rat

1 to 20 of 826 rows
1 to 20 of 1065 rows
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Expected Size
Chr
Start
Stop
Species
Match
10125DXMgh7230123381916733819400Ratregion
10888D12Wox1089122089438020894469Ratregion
11051D12Mit2217121961087019611091Ratregion
11052D12Wox11200121961088619611090Ratregion
11053D12Wox12202121961088919611095Ratregion
33911D12Mit6139121235161912351758Ratregion
33955D1Mit22124123140994231410080Ratregion
33961D12Mit5133121235161912351752Ratregion
34017D12Mit9142122184936621849508Ratregion
34246D12Mgh3118122423477724234895Ratregion
34417D12Mgh2163121983578919835952Ratregion
34729D12Mgh5124122806443328064557Ratregion
11449D12Wox14158122200342822003586Ratregion
11450D12Mgh12140122199658621996726Ratregion
11451D12Mgh13139122200341122003550Ratregion
33725D12Mit1241121502494215025183Ratregion
36025D12Rat23145122413905724139202Ratregion
36101D12Rat15167122830212328302290Ratregion
36119D12Rat94267122905763229057901Ratregion
36125D12Rat14163122862266528622828Ratregion
1 to 20 of 1065 rows

Peak: (D12Mit6)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21212,351,619 - 12,351,758 (+)MAPPER
Rnor_6.01214,419,775 - 14,419,913NCBI
Rnor_5.01216,444,048 - 16,444,186UniSTS
RGSC_v3.41212,770,195 - 12,770,333UniSTS
RGSC_v3.41212,770,194 - 12,770,333RGD
RGSC_v3.11212,800,123 - 12,800,261RGD
Celera1214,127,014 - 14,127,152UniSTS
RH 3.4 Map12163.4UniSTS
RH 3.4 Map12163.4RGD
RH 2.0 Map12136.0RGD


1 to 10 of 73 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
631560Apr1Acute phase response QTL 16.1orosomucoid 1 amount (VT:0010541)plasma orosomucoid 1 level (CMO:0001467)121914436246669029Rat
61443Btemp2Thermal response to stress QTL 23.30.000094body temperature trait (VT:0005535)core body temperature (CMO:0001036)121502518320794014Rat
8552964Pigfal17Plasma insulin-like growth factor 1 level QTL 173.5blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449546669029Rat
8693635Alc28Alcohol consumption QTL 282.70.439drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)122308134044726024Rat
61324Eae5Experimental allergic encephalomyelitis QTL 514nervous system integrity trait (VT:0010566)percentage of study population developing relapsing-remitting experimental autoimmune encephalomyelitis during a period of time (CMO:0001402)121961087046669029Rat
1331739Hrtrt14Heart rate QTL 143.56232heart pumping trait (VT:2000009)heart rate (CMO:0000002)12931821612829686Rat
9590147Scort7Serum corticosterone level QTL 713.610.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)12142110980Rat
1549829Scl48Serum cholesterol level QTL 485blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)12960327746669029Rat
61331Eau2Experimental allergic uveoretinitis QTL 20.0005uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)12852542328064601Rat
737822Alc10Alcohol consumption QTL 102.2consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)121961087040218516Rat

1 to 10 of 73 rows


Note Type Note Reference
qtl_cross_type intercross  
qtl_general 8% NaCl diet was started at 12 weeks of age and given for 12 weeks 1581737
qtl_general parental S allele was responsible for increased trait 1581737