Hsph1 (heat shock protein family H (Hsp110) member 1) - Rat Genome Database

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Gene: Hsph1 (heat shock protein family H (Hsp110) member 1) Rattus norvegicus
Analyze
Symbol: Hsph1
Name: heat shock protein family H (Hsp110) member 1
RGD ID: 1311609
Description: Predicted to enable adenyl-nucleotide exchange factor activity and alpha-tubulin binding activity. Predicted to be involved in protein folding. Predicted to act upstream of or within several processes, including chaperone cofactor-dependent protein refolding; negative regulation of intracellular signal transduction; and positive regulation of nitrogen compound metabolic process. Predicted to be located in cytoplasm and nucleoplasm. Predicted to be part of protein-containing complex. Predicted to be active in cytosol and nucleus. Predicted to colocalize with microtubule. Orthologous to human HSPH1 (heat shock protein family H (Hsp110) member 1); PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: heat shock 105/110 protein 1; heat shock 105kDa; heat shock 105kDa/110kDa protein 1; heat shock 110 kDa protein; heat shock protein 105; heat shock protein 105 kDa; Hsp105; LOC288444
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2125,390,916 - 5,410,224 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl125,390,922 - 5,410,224 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx126,069,228 - 6,088,216 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0126,692,653 - 6,711,641 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0125,720,173 - 5,739,161 (+)NCBIRnor_WKY
Rnor_6.0126,322,685 - 6,341,898 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl126,322,668 - 6,341,902 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0128,423,546 - 8,442,481 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4125,794,645 - 5,811,453 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1125,794,644 - 5,811,451 (+)NCBI
Celera127,162,640 - 7,181,902 (+)NCBICelera
Cytogenetic Map12p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(2,4,5-trichlorophenoxy)acetic acid  (ISO)
(E)-cinnamyl alcohol  (ISO)
(S)-amphetamine  (ISO)
1,2-dimethylhydrazine  (ISO)
1,4-phenylenediamine  (ISO)
1-chloro-2,4-dinitrobenzene  (ISO)
1-fluoro-2,4-dinitrobenzene  (ISO)
1-naphthyl isothiocyanate  (EXP,ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-tribromophenol  (ISO)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
2-hydroxypropanoic acid  (ISO)
2-methylcholine  (ISO)
2-nitrofluorene  (EXP)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3-phenylprop-2-enal  (ISO)
4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one  (EXP)
4-amino-2,6-dinitrotoluene  (EXP)
4-hydroxynon-2-enal  (ISO)
4-phenylbutyric acid  (ISO)
6-propyl-2-thiouracil  (EXP)
8-Br-cAMP  (ISO)
9-cis-retinoic acid  (EXP)
acetamide  (EXP)
acrylamide  (EXP,ISO)
aflatoxin B1  (EXP,ISO)
albendazole  (ISO)
all-trans-retinoic acid  (EXP)
amphibole asbestos  (ISO)
Aroclor 1254  (EXP)
arsenous acid  (ISO)
astemizole  (EXP)
atrazine  (ISO)
Aurin  (ISO)
benzo[a]pyrene  (ISO)
Benzo[ghi]perylene  (ISO)
bexarotene  (EXP)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP,ISO)
bleomycin A5  (ISO)
bortezomib  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
cadmium sulfate  (ISO)
caffeine  (ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
carvedilol  (EXP)
cefaloridine  (EXP)
celastrol  (ISO)
chlordecone  (ISO)
chloroethene  (ISO)
chloropicrin  (ISO)
chromium(6+)  (ISO)
cinnamyl alcohol  (ISO)
clofibrate  (ISO)
cobalt dichloride  (ISO)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
copper(II) sulfate  (ISO)
crocidolite asbestos  (ISO)
CU-O LINKAGE  (ISO)
Cuprizon  (ISO)
cyclophosphamide  (ISO)
cyclosporin A  (ISO)
decabromodiphenyl ether  (ISO)
deoxynivalenol  (ISO)
desferrioxamine B  (ISO)
diallyl disulfide  (EXP)
diarsenic trioxide  (ISO)
dibenz[a,h]anthracene  (ISO)
dibenzo[a,l]pyrene  (ISO)
diethylstilbestrol  (EXP)
dimethylarsinic acid  (ISO)
dioxygen  (EXP,ISO)
disulfiram  (ISO)
diuron  (EXP)
dorsomorphin  (ISO)
doxorubicin  (EXP,ISO)
elesclomol  (ISO)
endosulfan  (EXP)
enzyme inhibitor  (ISO)
ethanol  (ISO)
eugenol  (ISO)
fenofibrate  (ISO)
flutamide  (EXP)
folic acid  (ISO)
furan  (ISO)
gedunin  (ISO)
genistein  (EXP)
gentamycin  (EXP)
glyoxal  (ISO)
haloperidol  (ISO)
hemin  (ISO)
Indeno[1,2,3-cd]pyrene  (ISO)
indirubin  (ISO)
iron atom  (EXP,ISO)
iron(0)  (EXP,ISO)
isoeugenol  (ISO)
isoprenaline  (ISO)
ivermectin  (ISO)
lead diacetate  (ISO)
lead(0)  (ISO)
lead(2+)  (ISO)
leflunomide  (EXP)
Licochalcone B  (ISO)
linalool  (EXP)
lipopolysaccharide  (ISO)
mercury dibromide  (ISO)
metacetamol  (ISO)
metformin  (EXP)
methapyrilene  (EXP)
methylarsonic acid  (ISO)
methylisothiazolinone  (ISO)
methylmercury chloride  (ISO)
motexafin gadolinium  (ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
N-methylformamide  (ISO)
N-nitrosodiethylamine  (ISO)
N-nitrosodimethylamine  (EXP)
nefazodone  (EXP)
nickel atom  (EXP,ISO)
nimesulide  (EXP)
organoselenium compound  (ISO)
oxaliplatin  (EXP)
p-chloromercuribenzoic acid  (ISO)
paracetamol  (EXP,ISO)
perfluorooctanoic acid  (EXP)
phenethyl isothiocyanate  (ISO)
phenobarbital  (EXP,ISO)
PhIP  (EXP)
piperonyl butoxide  (EXP)
pirinixic acid  (EXP,ISO)
piroxicam  (ISO)
potassium dichromate  (EXP)
pregnenolone 16alpha-carbonitrile  (EXP)
propiconazole  (ISO)
prostaglandin A1  (ISO)
quercetin  (ISO)
rac-lactic acid  (ISO)
resveratrol  (ISO)
retinyl acetate  (ISO)
ritonavir  (ISO)
rotenone  (EXP,ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
silver(1+) nitrate  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (EXP,ISO)
sodium dichromate  (EXP,ISO)
sodium dodecyl sulfate  (ISO)
sulforaphane  (ISO)
sunitinib  (ISO)
tamoxifen  (ISO)
temozolomide  (ISO)
tert-butyl hydroperoxide  (ISO)
testosterone  (EXP,ISO)
tetrachloromethane  (EXP,ISO)
thalidomide  (ISO)
thapsigargin  (ISO)
thioacetamide  (EXP)
thiostrepton  (ISO)
titanium dioxide  (EXP,ISO)
topotecan  (EXP)
torcetrapib  (ISO)
trans-isoeugenol  (ISO)
trichloroethene  (EXP)
triptonide  (ISO)
troglitazone  (ISO)
trovafloxacin  (EXP)
tungsten  (EXP,ISO)
tunicamycin  (ISO)
urethane  (ISO)
usnic acid  (ISO)
valdecoxib  (EXP)
valproic acid  (EXP,ISO)
zinc acetate  (ISO)
zinc atom  (ISO)
zinc pyrithione  (ISO)
zinc(0)  (ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. GOA pipeline RGD automated data pipeline
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:9931472   PMID:12477932   PMID:12749852   PMID:14644449   PMID:15489334   PMID:16396499   PMID:16857185   PMID:17643418   PMID:18681888   PMID:19028714   PMID:19284651   PMID:19754877  
PMID:20458337   PMID:21231916   PMID:22871113   PMID:23349634   PMID:24318877   PMID:30053369   PMID:32360748  


Genomics

Comparative Map Data
Hsph1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2125,390,916 - 5,410,224 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl125,390,922 - 5,410,224 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx126,069,228 - 6,088,216 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0126,692,653 - 6,711,641 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0125,720,173 - 5,739,161 (+)NCBIRnor_WKY
Rnor_6.0126,322,685 - 6,341,898 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl126,322,668 - 6,341,902 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0128,423,546 - 8,442,481 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4125,794,645 - 5,811,453 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1125,794,644 - 5,811,451 (+)NCBI
Celera127,162,640 - 7,181,902 (+)NCBICelera
Cytogenetic Map12p11NCBI
HSPH1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381331,134,973 - 31,162,388 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1331,134,973 - 31,162,388 (-)EnsemblGRCh38hg38GRCh38
GRCh371331,709,110 - 31,736,525 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361330,608,762 - 30,634,117 (-)NCBINCBI36Build 36hg18NCBI36
Build 341330,608,764 - 30,634,117NCBI
Celera1312,778,480 - 12,803,835 (-)NCBICelera
Cytogenetic Map13q12.3NCBI
HuRef1312,522,150 - 12,547,508 (-)NCBIHuRef
CHM1_11331,678,336 - 31,703,689 (-)NCBICHM1_1
T2T-CHM13v2.01330,358,018 - 30,385,432 (-)NCBIT2T-CHM13v2.0
Hsph1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395149,540,308 - 149,562,594 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5149,537,752 - 149,559,841 (-)EnsemblGRCm39 Ensembl
GRCm385149,616,843 - 149,636,498 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5149,614,287 - 149,636,376 (-)EnsemblGRCm38mm10GRCm38
MGSCv375150,419,420 - 150,438,890 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365149,885,224 - 149,904,597 (-)NCBIMGSCv36mm8
Celera5147,617,650 - 147,637,130 (-)NCBICelera
Cytogenetic Map5G3NCBI
cM Map589.18NCBI
Hsph1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543114,680,498 - 14,706,182 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495543114,680,364 - 14,706,182 (+)NCBIChiLan1.0ChiLan1.0
HSPH1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11330,845,938 - 30,871,455 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1330,846,631 - 30,871,161 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01312,412,826 - 12,438,563 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
HSPH1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1258,972,942 - 8,998,404 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl258,972,724 - 8,997,893 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha259,015,922 - 9,040,982 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0259,077,842 - 9,102,910 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl259,077,554 - 9,102,903 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1258,977,129 - 9,002,182 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0258,985,129 - 9,010,177 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0259,027,003 - 9,052,061 (+)NCBIUU_Cfam_GSD_1.0
Hsph1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945170,073,174 - 170,096,453 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647225,855,694 - 25,879,062 (-)EnsemblSpeTri2.0
SpeTri2.0NW_00493647225,855,873 - 25,879,062 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HSPH1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl117,733,878 - 7,759,576 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1117,733,874 - 7,759,528 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2117,585,525 - 7,587,259 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Sscrofa10.2117,637,260 - 7,661,067 (-)NCBISscrofa10.2Sscrofa10.2susScr3
HSPH1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.139,999,471 - 10,026,106 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl310,000,109 - 10,026,449 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605734,342,051 - 34,369,001 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Hsph1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247766,988,576 - 7,015,846 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247766,988,591 - 7,013,621 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Hsph1
114 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:109
Count of miRNA genes:93
Interacting mature miRNAs:104
Transcripts:ENSRNOT00000001201
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300174Bw15Body weight QTL 152.93body mass (VT:0001259)body weight loss (CMO:0001399)1219318387Rat
2312418Kidm41Kidney mass QTL 413.70.0001kidney mass (VT:0002707)single kidney wet weight to body weight ratio (CMO:0000622)12119611090Rat
10755457Coatc14Coat color QTL 140.01759coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)12122591684Rat
6893681Bw109Body weight QTL 1092.30.004body mass (VT:0001259)body weight (CMO:0000012)12123297788Rat
1581516Cm56Cardiac mass QTL 564.20.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)12129333307Rat
1598855Bp294Blood pressure QTL 2943.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)12134851688Rat
7411660Foco28Food consumption QTL 2810.90.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12142110980Rat
9590086Insglur6Insulin/glucose ratio QTL 618.970.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)12142110980Rat
8694179Bw150Body weight QTL 1502.90.001body mass (VT:0001259)body weight gain (CMO:0000420)12142110980Rat
7411586Foco5Food consumption QTL 55.40.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12142110980Rat
7411595Foco9Food consumption QTL 940.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12142110980Rat
7411545Bw128Body weight QTL 1285.20.001body mass (VT:0001259)body weight gain (CMO:0000420)12142110980Rat
9590147Scort7Serum corticosterone level QTL 713.610.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)12142110980Rat
2303575Insul14Insulin level QTL 144blood insulin amount (VT:0001560)blood insulin level (CMO:0000349)12142450532Rat
737979Pia22Pristane induced arthritis QTL 2253.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)12144465750Rat
634351Apr5Acute phase response QTL 56.7blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)12144503507Rat
2302042Pia38Pristane induced arthritis QTL 383.50.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)12144503507Rat
7243862Mcs30Mammary carcinoma susceptibility QTL 308.62mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)127977298525593Rat
634350Apr4Acute phase response QTL 46orosomucoid 1 amount (VT:0010541)plasma orosomucoid 1 level (CMO:0001467)12117200546172005Rat
724526Uae3Urinary albumin excretion QTL 34.90.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)12390696910373166Rat

Markers in Region
RH129540  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2125,404,469 - 5,404,655 (-)MAPPERmRatBN7.2
Rnor_6.0126,328,232 - 6,328,417NCBIRnor6.0
Rnor_5.0128,429,093 - 8,429,278UniSTSRnor5.0
RGSC_v3.4125,805,613 - 5,805,798UniSTSRGSC3.4
Celera127,176,148 - 7,176,333UniSTS
RH 3.4 Map1240.36UniSTS
Cytogenetic Map12p11UniSTS
AI600071  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2125,409,995 - 5,410,129 (-)MAPPERmRatBN7.2
Rnor_6.0126,322,780 - 6,322,913NCBIRnor6.0
Rnor_5.0128,423,641 - 8,423,774UniSTSRnor5.0
RGSC_v3.4125,811,225 - 5,811,358UniSTSRGSC3.4
Celera127,181,674 - 7,181,807UniSTS
RH 3.4 Map1258.1UniSTS
Cytogenetic Map12p11UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 37 57 41 19 41 7 10 74 35 40 11 7
Low 6 1 1 1 1
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000001201   ⟹   ENSRNOP00000001201
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl125,390,922 - 5,410,224 (+)Ensembl
Rnor_6.0 Ensembl126,322,668 - 6,341,902 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000104544   ⟹   ENSRNOP00000095841
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl125,390,922 - 5,410,224 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000116960   ⟹   ENSRNOP00000082622
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl125,390,922 - 5,410,224 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000119657   ⟹   ENSRNOP00000089171
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl125,391,809 - 5,410,224 (+)Ensembl
RefSeq Acc Id: NM_001011901   ⟹   NP_001011901
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2125,390,990 - 5,410,224 (+)NCBI
Rnor_6.0126,322,685 - 6,341,898 (-)NCBI
Rnor_5.0128,423,546 - 8,442,481 (-)NCBI
RGSC_v3.4125,794,645 - 5,811,453 (+)RGD
Celera127,162,640 - 7,181,902 (+)RGD
Sequence:
RefSeq Acc Id: XM_039089153   ⟹   XP_038945081
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2125,390,916 - 5,410,224 (+)NCBI
RefSeq Acc Id: XM_039089155   ⟹   XP_038945083
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2125,391,217 - 5,410,224 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001011901 (Get FASTA)   NCBI Sequence Viewer  
  XP_038945081 (Get FASTA)   NCBI Sequence Viewer  
  XP_038945083 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH81945 (Get FASTA)   NCBI Sequence Viewer  
  EDL89519 (Get FASTA)   NCBI Sequence Viewer  
  Q66HA8 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001011901   ⟸   NM_001011901
- UniProtKB: Q66HA8 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000001201   ⟸   ENSRNOT00000001201
RefSeq Acc Id: XP_038945081   ⟸   XM_039089153
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZXF4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038945083   ⟸   XM_039089155
- Peptide Label: isoform X2
RefSeq Acc Id: ENSRNOP00000082622   ⟸   ENSRNOT00000116960
RefSeq Acc Id: ENSRNOP00000089171   ⟸   ENSRNOT00000119657
RefSeq Acc Id: ENSRNOP00000095841   ⟸   ENSRNOT00000104544

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q66HA8-F1-model_v2 AlphaFold Q66HA8 1-858 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698388
Promoter ID:EPDNEW_R8913
Type:initiation region
Name:Hsph1_1
Description:heat shock protein family H member 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0126,341,875 - 6,341,935EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1311609 AgrOrtholog
BioCyc Gene G2FUF-20203 BioCyc
Ensembl Genes ENSRNOG00000000902 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000001201 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOP00000082622 ENTREZGENE
  ENSRNOP00000082622.1 UniProtKB/TrEMBL
  ENSRNOP00000089171.1 UniProtKB/TrEMBL
  ENSRNOP00000095841.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000001201 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOT00000104544.1 UniProtKB/TrEMBL
  ENSRNOT00000116960 ENTREZGENE
  ENSRNOT00000116960.1 UniProtKB/TrEMBL
  ENSRNOT00000119657.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1270.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.60.34.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7121434 IMAGE-MGC_LOAD
InterPro ATPase_NBD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Heat_shock_70_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HSP70_C_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HSP70_peptide-bd_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Hsp_70_fam UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HSPH1_NBD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:288444 UniProtKB/Swiss-Prot
MGC_CLONE MGC:94016 IMAGE-MGC_LOAD
NCBI Gene 288444 ENTREZGENE
Pfam HSP70 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Hsph1 PhenoGen
PROSITE HSP70_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF100920 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF100934 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF53067 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I5ZXF4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AB23_RAT UniProtKB/TrEMBL
  A0A8I6GLC4_RAT UniProtKB/TrEMBL
  HS105_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-05-11 Hsph1  heat shock protein family H (Hsp110) member 1  Hsph1  heat shock 105/110 protein 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2011-04-27 Hsph1  heat shock 105/110 protein 1  Hsph1  heat shock 105kDa/110kDa protein 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-07     Hsph1  heat shock 105kDa/110kDa protein 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-04     Hsph1  heat shock 105kDa/110kDa protein 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Hsph1  heat shock 105kDa/110kDa protein 1  Hsp105  heat shock protein 105  Symbol and Name updated 1299863 APPROVED
2005-12-06 Hsp105  heat shock protein 105  Hsp105_predicted  heat shock protein 105 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Hsp105_predicted  heat shock protein 105 (predicted)      Symbol and Name status set to approved 70820 APPROVED