Mepce (methylphosphate capping enzyme) - Rat Genome Database

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Gene: Mepce (methylphosphate capping enzyme) Rattus norvegicus
Analyze
Symbol: Mepce
Name: methylphosphate capping enzyme
RGD ID: 1560550
Description: Predicted to enable 7SK snRNA binding activity and RNA 5'-gamma-phosphate methyltransferase activity. Predicted to be involved in RNA modification; positive regulation of protein localization to Cajal body; and positive regulation of snRNA transcription by RNA polymerase II. Predicted to act upstream of or within negative regulation of transcription by RNA polymerase II and positive regulation of G1/S transition of mitotic cell cycle. Predicted to be located in nucleus. Predicted to be part of 7SK snRNP. Orthologous to human MEPCE (methylphosphate capping enzyme); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amitrole.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 7SK snRNA methylphosphate capping enzyme; 7SK snRNA methylphosphate capping enzyme-like; LOC100910540; LOC304361; similar to Hypothetical protein MGC28888
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81224,548,596 - 24,553,315 (+)NCBIGRCr8
mRatBN7.21218,911,796 - 18,916,515 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1218,911,796 - 18,916,514 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1220,066,920 - 20,071,639 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01220,679,795 - 20,684,514 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01219,744,124 - 19,748,843 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01221,721,246 - 21,725,965 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1221,981,755 - 21,986,473 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl1221,721,837 - 21,725,435 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01223,742,114 - 23,746,833 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41219,848,913 - 19,853,632 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1220,717,705 - 20,722,424 (+)NCBICelera
Cytogenetic Map12q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
MepceRatpleomorphic xanthoastrocytoma  ISOMEPCE (Homo sapiens)8554872ClinVar Annotator: match by term: Pleomorphic xanthoastrocytomaClinVarPMID:28299358

1 to 20 of 65 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
MepceRat1,2-dimethylhydrazine multiple interactionsISOMepce (Mus musculus)6480464[1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of MEPCE mRNACTDPMID:22206623
MepceRat1,2-dimethylhydrazine increases expressionISOMepce (Mus musculus)64804641 and 2-Dimethylhydrazine results in increased expression of MEPCE mRNACTDPMID:22206623
MepceRat17beta-estradiol decreases expressionISOMepce (Mus musculus)6480464Estradiol results in decreased expression of MEPCE mRNACTDPMID:39298647
MepceRat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOMepce (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of MEPCE mRNACTDPMID:21570461
MepceRat2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of MEPCE mRNACTDPMID:33387578
MepceRat2-deoxy-D-glucose increases expressionISOMEPCE (Homo sapiens)6480464Deoxyglucose results in increased expression of MEPCE mRNACTDPMID:33770205
MepceRat4,4'-sulfonyldiphenol affects expressionISOMepce (Mus musculus)6480464bisphenol S affects the expression of MEPCE mRNACTDPMID:39298647
MepceRat6-propyl-2-thiouracil decreases expressionEXP 6480464Propylthiouracil results in decreased expression of MEPCE mRNACTDPMID:30047161
MepceRatamitrole decreases expressionEXP 6480464Amitrole results in decreased expression of MEPCE mRNACTDPMID:30047161
MepceRataristolochic acid A increases expressionISOMEPCE (Homo sapiens)6480464aristolochic acid I results in increased expression of MEPCE mRNACTDPMID:33212167
MepceRatatrazine decreases expressionISOMEPCE (Homo sapiens)6480464Atrazine results in decreased expression of MEPCE mRNACTDPMID:22378314
MepceRatbenzo[a]pyrene decreases methylationISOMEPCE (Homo sapiens)6480464Benzo(a)pyrene results in decreased methylation of MEPCE exonCTDPMID:27901495
MepceRatbenzo[a]pyrene diol epoxide I increases expressionISOMEPCE (Homo sapiens)64804647 more ...CTDPMID:19150397
MepceRatbisphenol A increases expressionEXP 6480464bisphenol A results in increased expression of MEPCE mRNACTDPMID:25181051 more ...
MepceRatbisphenol A affects expressionISOMEPCE (Homo sapiens)6480464bisphenol A affects the expression of MEPCE mRNACTDPMID:30903817
MepceRatbisphenol A decreases methylationISOMepce (Mus musculus)6480464bisphenol A results in decreased methylation of MEPCE promoterCTDPMID:27312807
MepceRatbleomycin A2 increases expressionISOMEPCE (Homo sapiens)6480464Bleomycin results in increased expression of MEPCE mRNACTDPMID:33770205
MepceRatbutanal decreases expressionISOMEPCE (Homo sapiens)6480464butyraldehyde results in decreased expression of MEPCE mRNACTDPMID:26079696
MepceRatcadmium dichloride decreases methylationEXP 6480464Cadmium Chloride results in decreased methylation of MEPCE promoterCTDPMID:22457795
MepceRatcaffeine increases phosphorylationISOMEPCE (Homo sapiens)6480464Caffeine results in increased phosphorylation of MEPCE proteinCTDPMID:35688186

1 to 20 of 65 rows

Biological Process
1 to 11 of 11 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
MepceRatmethylation involved_inIEAUniProtKB-KW:KW-04891600115GO_REF:0000043UniProtGO_REF:0000043
MepceRatnegative regulation of transcription by RNA polymerase II acts_upstream_of_or_withinISOMepce (Mus musculus)1624291MGI:107634 PMID:23154982RGDPMID:23154982
MepceRatnegative regulation of transcription by RNA polymerase II acts_upstream_of_or_withinIEAUniProtKB:Q8K3A9 and ensembl:ENSMUSP000000317401600115GO_REF:0000107EnsemblGO_REF:0000107
MepceRatpositive regulation of G1/S transition of mitotic cell cycle acts_upstream_of_or_withinISOMepce (Mus musculus)1624291 PMID:23154982RGDPMID:23154982
MepceRatpositive regulation of G1/S transition of mitotic cell cycle acts_upstream_of_or_withinIEAUniProtKB:Q8K3A9 and ensembl:ENSMUSP000000317401600115GO_REF:0000107EnsemblGO_REF:0000107
MepceRatpositive regulation of protein localization to Cajal body involved_inISOMEPCE (Homo sapiens)1624291 PMID:28254838RGDPMID:28254838
MepceRatpositive regulation of snRNA transcription by RNA polymerase II involved_inISOMEPCE (Homo sapiens)1624291 PMID:28254838RGDPMID:28254838
MepceRatRNA methylation involved_inISOMEPCE (Homo sapiens)1624291 PMID:17643375 more ...RGDPMID:17643375 more ...
MepceRatsnRNA metabolic process involved_inISOMEPCE (Homo sapiens)1624291 PMID:17643375 more ...RGDPMID:17643375 more ...
MepceRatsnRNA modification involved_inISOMEPCE (Homo sapiens)1624291 PMID:17643375 more ...RGDPMID:17643375 more ...
MepceRatsnRNA modification involved_inIBAFB:FBgn0037368 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
1 to 11 of 11 rows

Cellular Component

  

Molecular Function
1 to 14 of 14 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
MepceRat7SK snRNA binding enablesISOMEPCE (Homo sapiens)1624291 PMID:28431135RGDPMID:28431135
MepceRatmethyltransferase activity enablesIEAInterPro:IPR010675 and InterPro:IPR0241601600115GO_REF:0000002InterProGO_REF:0000002
MepceRatmethyltransferase activity enablesIEAUniProtKB-KW:KW-04891600115GO_REF:0000043UniProtGO_REF:0000043
MepceRatO-methyltransferase activity enablesIBAPANTHER:PTN000267975 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
MepceRatO-methyltransferase activity enablesIEAUniRule:UR0014197561600115GO_REF:0000104UniProtGO_REF:0000104
MepceRatprotein binding enablesISOMEPCE (Homo sapiens)1624291UniProtKB:O94992 more ...RGDPMID:30824372
MepceRatRNA 5'-gamma-phosphate methyltransferase activity enablesISOMEPCE (Homo sapiens)1624291 PMID:19906723 more ...RGDPMID:19906723 more ...
MepceRatRNA binding enablesISOMEPCE (Homo sapiens)1624291RNAcentral:URS0000734D8F_9606 PMID:30559425RGDPMID:30559425
MepceRatRNA methyltransferase activity enablesISOMEPCE (Homo sapiens)1624291 PMID:17643375 and PMID:24360279RGDPMID:17643375 and PMID:24360279
MepceRatRNA methyltransferase activity enablesIEAUniRule:UR0014197561600115GO_REF:0000104UniProtGO_REF:0000104
MepceRatRNA methyltransferase activity enablesIBAPANTHER:PTN000267975 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
MepceRatS-adenosylmethionine-dependent methyltransferase activity enablesISOMEPCE (Homo sapiens)1624291 PMID:17643375RGDPMID:17643375
MepceRatsnRNA binding enablesIBAFB:FBgn0037368 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
MepceRattransferase activity enablesIEAUniProtKB-KW:KW-08081600115GO_REF:0000043UniProtGO_REF:0000043
1 to 14 of 14 rows


#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
PMID:8889548   PMID:17643375   PMID:19906723   PMID:22658674   PMID:22681889   PMID:23154982   PMID:24360279   PMID:28254838   PMID:30559425  



Mepce
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81224,548,596 - 24,553,315 (+)NCBIGRCr8
mRatBN7.21218,911,796 - 18,916,515 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1218,911,796 - 18,916,514 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1220,066,920 - 20,071,639 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01220,679,795 - 20,684,514 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01219,744,124 - 19,748,843 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01221,721,246 - 21,725,965 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1221,981,755 - 21,986,473 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl1221,721,837 - 21,725,435 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01223,742,114 - 23,746,833 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41219,848,913 - 19,853,632 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1220,717,705 - 20,722,424 (+)NCBICelera
Cytogenetic Map12q12NCBI
MEPCE
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387100,428,790 - 100,434,118 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7100,428,322 - 100,434,126 (+)EnsemblGRCh38hg38GRCh38
GRCh377100,026,413 - 100,031,741 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36799,865,465 - 99,869,677 (+)NCBINCBI36Build 36hg18NCBI36
Celera794,756,212 - 94,761,548 (+)NCBICelera
Cytogenetic Map7q22.1NCBI
HuRef794,659,849 - 94,665,185 (+)NCBIHuRef
CHM1_1799,957,026 - 99,962,362 (+)NCBICHM1_1
T2T-CHM13v2.07101,668,175 - 101,674,196 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2799,386,498 - 99,391,834 (+)NCBI
Mepce
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395137,780,168 - 137,785,915 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5137,780,168 - 137,785,917 (-)EnsemblGRCm39 Ensembl
GRCm385137,781,906 - 137,786,701 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5137,781,906 - 137,787,655 (-)EnsemblGRCm38mm10GRCm38
MGSCv375138,223,134 - 138,227,929 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365138,011,709 - 138,015,961 (-)NCBIMGSCv36mm8
Celera5134,768,335 - 134,773,130 (-)NCBICelera
Cytogenetic Map5G2NCBI
cM Map576.7NCBI
Mepce
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955573526,613 - 530,286 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955573526,083 - 531,222 (-)NCBIChiLan1.0ChiLan1.0
MEPCE
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26118,342,164 - 118,347,440 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan17166,607,596 - 166,612,072 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0792,457,967 - 92,463,102 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17105,859,584 - 105,865,312 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7105,861,205 - 105,864,739 (+)Ensemblpanpan1.1panPan2
MEPCE
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.169,234,316 - 9,239,160 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl69,234,356 - 9,239,859 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha610,938,563 - 10,943,659 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.069,168,084 - 9,173,182 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl69,168,095 - 9,172,830 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.169,020,522 - 9,025,618 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.068,998,101 - 9,003,195 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.069,180,481 - 9,185,577 (-)NCBIUU_Cfam_GSD_1.0
Mepce
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344133,527,114 - 133,531,605 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936543504,671 - 509,497 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936543504,686 - 509,419 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MEPCE
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl38,357,289 - 8,364,661 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.138,356,602 - 8,361,798 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.237,700,143 - 7,704,903 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MEPCE
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12812,771,822 - 12,776,345 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2812,771,391 - 12,775,961 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660703,514,965 - 3,520,629 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mepce
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474016,641,484 - 16,644,989 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474016,640,777 - 16,645,788 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

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Variants in Mepce
5 total Variants

Predicted Target Of
Summary Value
Count of predictions:99
Count of miRNA genes:74
Interacting mature miRNAs:78
Transcripts:ENSRNOT00000001871, ENSRNOT00000073353
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 48 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
2312418Kidm41Kidney mass QTL 413.70.0001kidney mass (VT:0002707)single kidney wet weight to body weight ratio (CMO:0000622)12119611090Rat
61443Btemp2Thermal response to stress QTL 23.30.000094body temperature trait (VT:0005535)core body temperature (CMO:0001036)121502518320794014Rat
8552964Pigfal17Plasma insulin-like growth factor 1 level QTL 173.5blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449546669029Rat
7411641Foco19Food consumption QTL 1927.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12556449546669029Rat
1549912Bp268Blood pressure QTL 268arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)101318273646669029Rat
2302060Pia37Pristane induced arthritis QTL 376.10.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)121319815746669029Rat
9590147Scort7Serum corticosterone level QTL 713.610.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)12142110980Rat
1641928Alcrsp5Alcohol response QTL 5response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)121281238546669029Rat
8552912Pigfal6Plasma insulin-like growth factor 1 level QTL 65blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449846669029Rat
1549829Scl48Serum cholesterol level QTL 485blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)12960327746669029Rat

1 to 10 of 48 rows
BE101310  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21218,914,771 - 18,914,954 (+)MAPPERmRatBN7.2
Rnor_6.01221,724,222 - 21,724,404NCBIRnor6.0
Rnor_6.01221,984,731 - 21,984,913NCBIRnor6.0
Rnor_5.01224,001,779 - 24,001,961UniSTSRnor5.0
Rnor_5.01223,745,090 - 23,745,272UniSTSRnor5.0
RGSC_v3.41219,850,474 - 19,850,656UniSTSRGSC3.4
Celera1220,720,681 - 20,720,863UniSTS
RH 3.4 Map12264.3UniSTS
Cytogenetic Map12q12UniSTS
WIAF-1510  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_5.01223,746,595 - 23,746,749NCBIRnor5.0
RGSC_v3.41219,848,997 - 19,849,150UniSTSRGSC3.4
Cytogenetic Map12q12UniSTS
RH125705  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21218,916,127 - 18,916,398 (+)MAPPERmRatBN7.2
Rnor_6.01221,725,578 - 21,725,848NCBIRnor6.0
Rnor_6.01221,986,087 - 21,986,357NCBIRnor6.0
Rnor_5.01223,746,446 - 23,746,716UniSTSRnor5.0
Rnor_5.01224,003,135 - 24,003,405UniSTSRnor5.0
RGSC_v3.41219,849,030 - 19,849,300UniSTSRGSC3.4
Celera1220,722,037 - 20,722,307UniSTS
Cytogenetic Map12q12UniSTS
C78815  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21218,916,125 - 18,916,209 (+)MAPPERmRatBN7.2
Rnor_6.01221,725,576 - 21,725,659NCBIRnor6.0
Rnor_6.01221,986,085 - 21,986,168NCBIRnor6.0
Rnor_5.01223,746,444 - 23,746,527UniSTSRnor5.0
Rnor_5.01224,003,133 - 24,003,216UniSTSRnor5.0
RGSC_v3.41219,849,219 - 19,849,302UniSTSRGSC3.4
Celera1220,722,035 - 20,722,118UniSTS
Cytogenetic Map12q12UniSTS
RH142264  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21218,916,282 - 18,916,482 (+)MAPPERmRatBN7.2
Rnor_6.01221,725,733 - 21,725,932NCBIRnor6.0
Rnor_6.01221,986,242 - 21,986,441NCBIRnor6.0
Rnor_5.01223,746,601 - 23,746,800UniSTSRnor5.0
Rnor_5.01224,003,290 - 24,003,489UniSTSRnor5.0
RGSC_v3.41219,848,946 - 19,849,145UniSTSRGSC3.4
Celera1220,722,192 - 20,722,391UniSTS
Cytogenetic Map12q12UniSTS




circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hepatobiliary system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
30 61 28 28 28 28 82 30 61 24 26



Ensembl Acc Id: ENSRNOT00000001871   ⟹   ENSRNOP00000001871
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1218,911,796 - 18,916,514 (+)Ensembl
Rnor_6.0 Ensembl1221,981,755 - 21,986,473 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000073353   ⟹   ENSRNOP00000067286
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1221,721,837 - 21,725,435 (+)Ensembl
RefSeq Acc Id: NM_001100678   ⟹   NP_001094148
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81224,548,596 - 24,553,315 (+)NCBI
mRatBN7.21218,911,796 - 18,916,515 (+)NCBI
Rnor_6.01221,721,246 - 21,725,965 (+)NCBI
Rnor_5.01223,742,114 - 23,746,833 (+)NCBI
RGSC_v3.41219,848,913 - 19,853,632 (-)RGD
Celera1220,717,705 - 20,722,424 (+)RGD
Sequence:
Protein RefSeqs NP_001094148 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH88435 (Get FASTA)   NCBI Sequence Viewer  
  EDM13235 (Get FASTA)   NCBI Sequence Viewer  
  EDM13236 (Get FASTA)   NCBI Sequence Viewer  
  EDM13237 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000001871
  ENSRNOP00000001871.4
RefSeq Acc Id: NP_001094148   ⟸   NM_001100678
- UniProtKB: G3V656 (UniProtKB/TrEMBL),   A6IZZ6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000067286   ⟸   ENSRNOT00000073353
Ensembl Acc Id: ENSRNOP00000001871   ⟸   ENSRNOT00000001871
Bin3-type SAM

Name Modeler Protein Id AA Range Protein Structure
AF-G3V656-F1-model_v2 AlphaFold G3V656 1-660 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen



1 to 27 of 27 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-19722 BioCyc
Ensembl Genes ENSRNOG00000001387 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOG00000045911 Ensembl
Ensembl Transcript ENSRNOT00000001871 ENTREZGENE
  ENSRNOT00000001871.6 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.150 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7125256 IMAGE-MGC_LOAD
InterPro Bin3 UniProtKB/TrEMBL
  Bin3-like UniProtKB/TrEMBL
  BIN3_SAM-bd_dom UniProtKB/TrEMBL
  Methyltranfer_dom UniProtKB/TrEMBL
  SAM-dependent_MTases-like UniProtKB/TrEMBL
KEGG Report rno:304361 UniProtKB/TrEMBL
MGC_CLONE MGC:95069 IMAGE-MGC_LOAD
NCBI Gene 304361 ENTREZGENE
PANTHER 7SK SNRNA METHYLPHOSPHATE CAPPING ENZYME UniProtKB/TrEMBL
  PTHR12315 UniProtKB/TrEMBL
Pfam Bin3 UniProtKB/TrEMBL
  Methyltransf_31 UniProtKB/TrEMBL
PhenoGen Mepce PhenoGen
PROSITE BIN3_SAM UniProtKB/TrEMBL
RatGTEx ENSRNOG00000001387 RatGTEx
  ENSRNOG00000045911 RatGTEx
Superfamily-SCOP SSF53335 UniProtKB/TrEMBL
UniProt A6IZZ6 ENTREZGENE, UniProtKB/TrEMBL
  G3V656 ENTREZGENE, UniProtKB/TrEMBL
  Q5I0E0_RAT UniProtKB/TrEMBL
1 to 27 of 27 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Mepce  methylphosphate capping enzyme  LOC100910540  7SK snRNA methylphosphate capping enzyme-like  Data merged from RGD:6497906 737654 PROVISIONAL
2012-07-05 LOC100910540  7SK snRNA methylphosphate capping enzyme-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-03-04 Mepce  methylphosphate capping enzyme  LOC304361  similar to Hypothetical protein MGC28888  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-02-09 LOC304361  similar to Hypothetical protein MGC28888      Symbol and Name status set to provisional 70820 PROVISIONAL