Il31 (interleukin 31) - Rat Genome Database

Name: Il31
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: Il31 (interleukin 31) Rattus norvegicus

Analyze

Symbol:

Il31

Name:

interleukin 31

RGD ID:

1585183

Description:

Predicted to enable cytokine activity and oncostatin-M receptor binding activity. Predicted to be involved in signal transduction. Predicted to be located in extracellular space. Orthologous to human IL31 (interleukin 31); INTERACTS WITH 1-chloro-2,4-dinitrobenzene (ortholog); aristolochic acid A (ortholog); arsane (ortholog).

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

AABR07036324.1; hypothetical protein LOC690028; interleukin-31; LOC690028

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	IL31 (interleukin 31)	HGNC	EggNOG, Ensembl, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Il31 (interleukin 31)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Il31 (interleukin 31)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	IL31 (interleukin 31)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	IL31 (interleukin 31)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Il31 (interleukin 31)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	IL31 (interleukin 31)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	IL31 (interleukin 31)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Il31 (interleukin 31)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	SNAPC2 (small nuclear RNA activating complex polypeptide 2)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	IL31 (interleukin 31)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Mus musculus (house mouse):	Il31 (interleukin 31)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	12	38,756,231 - 38,765,917 (+)	NCBI		GRCr8
mRatBN7.2	12	33,095,108 - 33,105,026 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	12	33,092,097 - 33,105,037 (+)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	12	38,527,575 - 38,538,086 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	12	38,524,518 - 38,537,386 (+)	NCBI	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	12	40,408,692 - 40,417,840 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	12	34,241,470 - 34,243,890 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	12	34,779,143 - 34,790,224 (+)	NCBI		Celera
Cytogenetic Map	12	q16	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

atopic dermatitis (ISO)

genetic disease (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1-chloro-2,4-dinitrobenzene (ISO)

aristolochic acid A (ISO)

arsane (ISO)

arsenic atom (ISO)

benzalkonium chloride (ISO)

benzo[a]pyrene (ISO)

CGP 52608 (ISO)

chlorpyrifos (ISO)

epoxiconazole (ISO)

fragrance (ISO)

lead diacetate (ISO)

nickel atom (ISO)

pirinixic acid (ISO)

resveratrol (ISO)

triptonide (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

signal transduction (IEA)

Cellular Component

extracellular space (IBA,ISO)

membrane (IEA)

Molecular Function

cytokine activity (IBA,ISO)

cytokine receptor binding (IBA,ISO)

oncostatin-M receptor binding (ISO)

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:21182835

Genomics

Comparative Map Data

Il31
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	12	38,756,231 - 38,765,917 (+)	NCBI		GRCr8
mRatBN7.2	12	33,095,108 - 33,105,026 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	12	33,092,097 - 33,105,037 (+)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	12	38,527,575 - 38,538,086 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	12	38,524,518 - 38,537,386 (+)	NCBI	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	12	40,408,692 - 40,417,840 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	12	34,241,470 - 34,243,890 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	12	34,779,143 - 34,790,224 (+)	NCBI		Celera
Cytogenetic Map	12	q16	NCBI

IL31
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	12	122,172,029 - 122,174,221 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	12	122,172,029 - 122,174,221 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	12	122,656,576 - 122,658,768 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	12	121,222,530 - 121,224,699 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	12	121,181,456 - 121,183,626	NCBI
Celera	12	122,245,842 - 122,248,011 (-)	NCBI		Celera
Cytogenetic Map	12	q24.31	NCBI
HuRef	12	119,617,511 - 119,619,680 (-)	NCBI		HuRef
CHM1_1	12	122,624,861 - 122,627,030 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	12	122,167,819 - 122,170,011 (-)	NCBI		T2T-CHM13v2.0

Il31
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	5	123,618,215 - 123,620,686 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	5	123,618,220 - 123,627,552 (-)	Ensembl		GRCm39 Ensembl
GRCm38	5	123,480,152 - 123,482,623 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	5	123,480,157 - 123,489,489 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	5	123,930,162 - 123,932,110 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	5	123,740,775 - 123,742,719 (-)	NCBI		MGSCv36	mm8
Celera	5	120,567,286 - 120,569,233 (-)	NCBI		Celera
Cytogenetic Map	5	F	NCBI
cM Map	5	63.0	NCBI

Il31
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955482	6,387,289 - 6,389,361 (+)	NCBI	ChiLan1.0	ChiLan1.0

IL31
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	10	130,259,917 - 130,269,413 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	12	130,256,293 - 130,265,789 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	12	119,773,030 - 119,775,963 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	12	123,140,531 - 123,142,700 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	12	123,140,531 - 123,142,700 (-)	Ensembl	panpan1.1		panPan2

IL31
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	26	7,173,151 - 7,175,195 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	26	7,172,451 - 7,175,195 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	26	7,333,283 - 7,335,327 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	26	7,424,886 - 7,426,930 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	26	7,424,187 - 7,426,930 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	26	7,357,034 - 7,359,078 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	26	7,447,633 - 7,449,677 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	26	7,403,478 - 7,405,522 (+)	NCBI		UU_Cfam_GSD_1.0

Il31
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	157,179,801 - 157,181,785 (-)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936558	2,297,641 - 2,299,625 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

IL31
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1	14	30,553,688 - 30,559,545 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	14	32,060,905 - 32,063,997 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

IL31
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	11	117,524,430 - 117,527,159 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	11	117,525,273 - 117,527,032 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666136	364,340 - 366,447 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Il31
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624747	22,411,108 - 22,412,632 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Il31
71 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	41
Count of miRNA genes:	40
Interacting mature miRNAs:	40
Transcripts:	ENSRNOT00000030573
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1598855	Bp294	Blood pressure QTL 294	3.5		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	12	1	34851688	Rat
7411660	Foco28	Food consumption QTL 28	10.9	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	1	42110980	Rat
9590086	Insglur6	Insulin/glucose ratio QTL 6	18.97	0.001	blood insulin amount (VT:0001560)	calculated plasma insulin level (CMO:0002170)	12	1	42110980	Rat
8694179	Bw150	Body weight QTL 150	2.9	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	12	1	42110980	Rat
7411586	Foco5	Food consumption QTL 5	5.4	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	1	42110980	Rat
7411595	Foco9	Food consumption QTL 9	4	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	1	42110980	Rat
7411545	Bw128	Body weight QTL 128	5.2	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	12	1	42110980	Rat
9590147	Scort7	Serum corticosterone level QTL 7	13.61	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	12	1	42110980	Rat
2303575	Insul14	Insulin level QTL 14	4		blood insulin amount (VT:0001560)	blood insulin level (CMO:0000349)	12	1	42450532	Rat
737979	Pia22	Pristane induced arthritis QTL 22	53.1		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	12	1	44465750	Rat
634351	Apr5	Acute phase response QTL 5	6.7		blood interleukin-6 amount (VT:0008595)	plasma interleukin-6 level (CMO:0001927)	12	1	44503507	Rat
2302042	Pia38	Pristane induced arthritis QTL 38	3.5	0.001	blood immunoglobulin amount (VT:0002460)	serum immunoglobulin G1 level (CMO:0002115)	12	1	44503507	Rat
634350	Apr4	Acute phase response QTL 4	6		orosomucoid 1 amount (VT:0010541)	plasma orosomucoid 1 level (CMO:0001467)	12	1172005	46172005	Rat
8552918	Pigfal7	Plasma insulin-like growth factor 1 level QTL 7			blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	12	5564495	46669029	Rat
7411547	Bw129	Body weight QTL 129		0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	6	5564495	46669029	Rat
7411597	Foco10	Food consumption QTL 10		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	5564495	46669029	Rat
7411641	Foco19	Food consumption QTL 19	27.7	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	5564495	46669029	Rat
8552964	Pigfal17	Plasma insulin-like growth factor 1 level QTL 17	3.5		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	12	5564495	46669029	Rat
7411588	Foco6	Food consumption QTL 6		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	5564495	46669029	Rat
8552912	Pigfal6	Plasma insulin-like growth factor 1 level QTL 6	5		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	12	5564498	46669029	Rat
10059594	Kidm46	Kidney mass QTL 46	3.79	0.025	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	12	6107579	46669029	Rat
1302792	Scl21	Serum cholesterol level QTL 21	3.8	0.0011	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	12	7196730	46669029	Rat
1549829	Scl48	Serum cholesterol level QTL 48	5		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	12	9603277	46669029	Rat
2293699	Bss49	Bone structure and strength QTL 49	5.61	0.0001	lumbar vertebra size trait (VT:0010518)	lumbar vertebra trabecular cross-sectional area (CMO:0001692)	12	10474137	46669029	Rat
2300186	Bmd59	Bone mineral density QTL 59	7.1	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	12	10474137	46669029	Rat
1331761	Bp218	Blood pressure QTL 218	2.973		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	12	11073825	45055165	Rat
61404	Bw120	Body weight QTL 120	5.1		body mass (VT:0001259)	body mass index (BMI) (CMO:0000105)	12	12351619	46669029	Rat
1641928	Alcrsp5	Alcohol response QTL 5			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	12	12812385	46669029	Rat
2303569	Gluco44	Glucose level QTL 44	2		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	12	12812385	46669029	Rat
1549902	Bp269	Blood pressure QTL 269			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	12	13182736	46669029	Rat
1549912	Bp268	Blood pressure QTL 268			arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	10	13182736	46669029	Rat
2302060	Pia37	Pristane induced arthritis QTL 37	6.1	0.001	blood immunoglobulin amount (VT:0002460)	serum immunoglobulin G1 level (CMO:0002115)	12	13198157	46669029	Rat
61421	Cia12	Collagen induced arthritis QTL 12	4.6		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	12	13635523	35682913	Rat
631543	Bp83	Blood pressure QTL 83	5.8		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	12	15550826	38478808	Rat
631560	Apr1	Acute phase response QTL 1	6.1		orosomucoid 1 amount (VT:0010541)	plasma orosomucoid 1 level (CMO:0001467)	12	19144362	46669029	Rat
737822	Alc10	Alcohol consumption QTL 10	2.2		consumption behavior trait (VT:0002069)	ethanol drink intake rate (CMO:0001407)	12	19610870	40218516	Rat
5684888	Pia42	Pristane induced arthritis QTL 42			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	12	19610870	42828880	Rat
61324	Eae5	Experimental allergic encephalomyelitis QTL 5	14		nervous system integrity trait (VT:0010566)	percentage of study population developing relapsing-remitting experimental autoimmune encephalomyelitis during a period of time (CMO:0001402)	12	19610870	46669029	Rat
1298081	Cia25	Collagen induced arthritis QTL 25	4.7		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	12	19610889	35682913	Rat
70213	Niddm27	Non-insulin dependent diabetes mellitus QTL 27	3.72		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	12	19835789	38193007	Rat
7411643	Foco20	Food consumption QTL 20		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	20328819	46669029	Rat
70169	Eae13	Experimental allergic encephalomyelitis QTL 13		0.032	nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)	12	24139202	36638073	Rat
1556747	Calcic1	Intracellular calcium level QTL 1		3.6	platelet calcium amount (VT:0010500)	platelet intracellular calcium level (CMO:0000922)	12	28064433	40130419	Rat
1300175	Cm5	Cardiac mass QTL 5	3.78		heart mass (VT:0007028)	heart left ventricle weight to body weight ratio (CMO:0000530)	12	28064433	45899022	Rat
1600386	Calcic2	Intracellular calcium level QTL 2		0.001	platelet physiology trait (VT:0005464)	platelet intracellular calcium level (CMO:0000922)	12	28064433	46669029	Rat
1331787	Rf41	Renal function QTL 41	2.998		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal blood flow rate (CMO:0001168)	12	28064557	40218380	Rat
631829	Alc6	Alcohol consumption QTL 6	4.7		consumption behavior trait (VT:0002069)	ethanol drink intake rate (CMO:0001407)	12	28607526	37691617	Rat
1300162	Bp188	Blood pressure QTL 188	3.19		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	12	32103174	45899022	Rat

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_008760389	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008769274	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017598514	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017604482	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AB253490	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000012	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000030573 ⟹ ENSRNOP00000037716

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	12	33,092,097 - 33,105,037 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000099332 ⟹ ENSRNOP00000093601

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	12	33,102,489 - 33,105,037 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000105530 ⟹ ENSRNOP00000079495

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	12	33,095,263 - 33,105,037 (+)	Ensembl

RefSeq Acc Id:

XM_017598514 ⟹ XP_017454003

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	38,756,231 - 38,765,917 (+)	NCBI
mRatBN7.2	12	33,095,108 - 33,105,026 (+)	NCBI
Rnor_6.0	12	38,527,575 - 38,538,086 (+)	NCBI

Sequence:

show sequence

TGGGCCTGGGGCTAGAGCTCAATTGAAAGAATTTATCTTGAATTCAGAACCCAGCACTGCAAAA
ACCAAGGTGAAAGACTTGCCATTGTGGCGTAATAATGGTTGGAATTCTGCAGCTTTTGTGGAAA
GTGAAAGCCAAGAACAGGGGAGGCTGACAGCACATGCTCACCGCTCACAGGACCATAGTATCTC
TCTCTTGTTGACCCTCGACTTGCTGGCATGGTGGTGCACTCTTCTAATCCCAGCTCTAGGGAGG
TGGAGGCAAGAGGATCCCAAATCTGGGCTACATAGTGCAACCTCTTCTTATGAAAACAGTTATC
TGCATAGCCCAAGGCTGGGTGGGCTGATGTGTCATAGTGGGAGGAAGGACTCCCGGCGCCCCCA
CCACTCCCCGAGGATTTATACAAGTTCAGTGATGGAGGAGATTTTCTTCAGTGGTGAAGCCATT
GGACCGACAAAGCCCGCCCTGGTGCTGCTGTGCTGTGTAGGAGCCTGGCTGGCCATCTGCAGCT
CCTCCTTTGGTGCACCCATATCAAAGACAAATATACAACGTACACTTGAACTCTTGAAAGAGGA
GTCGAAGGCTCTTTATGAAGACTATAACAAAACCGAGGCATCTGGGATATCGCCAGATGAGTCG
CTACAGCTGCCGTGTTTCAGCCTGGGCCGAGAAGCACTAACCAACATTTCAGGCCTCAAAGCAT
ACCTGGAGGAAGTCAAATCGTTGAGCAAGAACACAGTAGATACTACTAAGCTCACAAAACGGCT
GGTCGACATCAGCTGTTTGAACCCACTGAATGTAAACATTTCCAGGCCTCAAAAAACTGACTCC
TACACTAAAAAAACATTCATACTTAGTGTTTTAAAGAAGTTCTCAGACTGCATGGCAGAAGTGC
AGGCTAAAGACAATATATGCTGAGCGACGGCGGGGAGAGCCCAGTGTCCTGGGACAGCTGAGCC
TGCAATGTAGGACTTAACCCCAAAGAGACTGTGCCGTCGTAACTAGCCATGTTATTTATATGTT
TTTGTTCTGTCCATTGAAATCTTATTCTTCTACCCTGTAGGGACTGGAATTTGCAGATTATATT
TATTTATTGGTATTTATGTACTGAGTTTGTTAACGCTCCATGGAGGAGCCCTCAGAGTCTATTT
AATAAATTATACCGACACGATCTCAGTAATCAGTTTTGGAGTTTGTCAGAGGATGGGGATGTTC
TGGAAATAGTGTTTATGTTGCTGGCTTCTCCCACCAATTACGGACAAACAATCCCAGCAGCATC
ACGTGTCTGATAAACATCTTTGTTCCAGGCGGGCCATAAGTCCGATCACTGTCGTTTTGGTGTG
TGGGCTGGGAGACTTCAGGAAAGAAGTCATTTAGTCACTTAGTCAAGGTTACGCACCTGTTTGG
CGATATACCCAGATTCCAGCTCGGACTGCATTATTCTGCCCGACCTCAGTTCTTCCCTCGGCAG
TGACTGAGTCTCAGGGACACTGACTCAGGGCAGTAACTCAGTATCCATGCACAATTGCGACTGC
ATTCCCAAGTCACTTCTTTGACCAATTCTGTAGGGACATCTTCACGGCAGACATAACGGTTTGC
TGTGTGAGTAGTAGCGAGTCCTTGAGCATTGGTAAGGTTCTCAGTGTGCGTCCGGATGAAGGGG
TCTCAAAGTATCTGGGAACCGTTCAGCAGCAACAGCGTCATGTTGGAAACACAAGGCCTTGATC
CATCTGCTCACTCCCAGGGTCTTAGTTTTGTTTGGGAAACACTGAGGATCAAACCCAGGGCCTT
GAGCATGGTAGCCTATGAGCCTGAGACGAGCCATCAGCCCCATAGCCATGGTTTTGAAGCCTCC
TAAGCACTCATTT

hide sequence

Protein Sequences


Protein RefSeqs	XP_017454003	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000037716.6
	ENSRNOP00000079495
	ENSRNOP00000079495.1
	ENSRNOP00000093601.1

RefSeq Acc Id:	XP_017454003 ⟸ XM_017598514
- UniProtKB:	A0A8I5ZNP8 (UniProtKB/TrEMBL), A0A8I6AK60 (UniProtKB/TrEMBL)
- Sequence:	show sequence MCHSGRKDSRRPHHSPRIYTSSVMEEIFFSGEAIGPTKPALVLLCCVGAWLAICSSSFGAPISK TNIQRTLELLKEESKALYEDYNKTEASGISPDESLQLPCFSLGREALTNISGLKAYLEEVKSLS KNTVDTTKLTKRLVDISCLNPLNVNISRPQKTDSYTKKTFILSVLKKFSDCMAEVQAKDNIC hide sequence

RefSeq Acc Id:

ENSRNOP00000037716 ⟸ ENSRNOT00000030573

RefSeq Acc Id:

ENSRNOP00000093601 ⟸ ENSRNOT00000099332

RefSeq Acc Id:

ENSRNOP00000079495 ⟸ ENSRNOT00000105530

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3ZIP0-F1-model_v2	AlphaFold	D3ZIP0	1-191	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1585183	AgrOrtholog
BioCyc Gene	G2FUF-19312	BioCyc
Ensembl Genes	ENSRNOG00000026192	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000030573.6	UniProtKB/TrEMBL
	ENSRNOT00000099332.1	UniProtKB/TrEMBL
	ENSRNOT00000105530.1	UniProtKB/TrEMBL
InterPro	IL-31	UniProtKB/TrEMBL
KEGG Report	rno:690028	UniProtKB/TrEMBL
NCBI Gene	690028	ENTREZGENE
PANTHER	INTERLEUKIN-31	UniProtKB/TrEMBL
	PTHR38652	UniProtKB/TrEMBL
Pfam	IL31	UniProtKB/TrEMBL
PhenoGen	Il31	PhenoGen
RatGTEx	ENSRNOG00000026192	RatGTEx
UniProt	A0A8I5ZNP8	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6AK60	ENTREZGENE, UniProtKB/TrEMBL
	D3ZIP0_RAT	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2022-06-02	Il31	interleukin 31	AABR07036324.1		Data merged from RGD:15003626	737654	PROVISIONAL
2019-11-08	AABR07036324.1				Symbol and Name status set to provisional	45752	PROVISIONAL
2012-10-02	Il31	interleukin 31	LOC690028	hypothetical protein LOC690028	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-11-19	LOC690028	hypothetical protein LOC690028			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD

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Imported Disease Annotations - ClinVar

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