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Gene: Ran (RAN, member RAS oncogene family) Rattus norvegicus
Symbol: Ran
Name: RAN, member RAS oncogene family
Description: Exhibits several functions, including dynein intermediate chain binding activity; importin-alpha family protein binding activity; and purine ribonucleoside binding activity. Predicted to contribute to pre-miRNA binding activity. Involved in several processes, including cellular response to mineralocorticoid stimulus; hippocampus development; and spermatid development. Localizes to several cellular components, including manchette; nucleus; and sperm flagellum. Predicted to colocalize with chromatin. Used to study sciatic neuropathy. Human ortholog(s) of this gene implicated in type 1 diabetes mellitus. Orthologous to human RAN (RAN, member RAS oncogene family); PARTICIPATES IN CRM1 export pathway; microRNA pathway; nuclear factor kappa B signaling pathway; INTERACTS WITH (+)-schisandrin B; 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 1-bromopropane.
Type: protein-coding
Also known as: GTP-binding nuclear protein Ran; GTPase Ran; ras-like protein TC4; ras-related nuclear protein
Homo sapiens (human) : RAN (RAN, member RAS oncogene family)  HGNC  Alliance
Mus musculus (house mouse) : Ran (RAN, member RAS oncogene family)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ran (RAN, member RAS oncogene family)
Pan paniscus (bonobo/pygmy chimpanzee) : RAN (RAN, member RAS oncogene family)
Canis lupus familiaris (dog) : RAN (RAN, member RAS oncogene family)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ran (RAN, member RAS oncogene family)
Sus scrofa (pig) : RAN (RAN, member RAS oncogene family)
Chlorocebus sabaeus (African green monkey) : RAN (RAN, member RAS oncogene family)
Heterocephalus glaber (naked mole-rat) : Ran (RAN, member RAS oncogene family)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01231,319,556 - 31,324,105 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1231,320,624 - 31,323,810 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01233,245,991 - 33,250,540 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41228,736,786 - 28,739,921 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11228,600,176 - 28,603,309 (-)NCBI
Celera1229,370,202 - 29,373,337 (-)NCBICelera
Cytogenetic Map12q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Ran
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 620367
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.