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Gene: Ppp1cc (protein phosphatase 1 catalytic subunit gamma) Rattus norvegicus
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Symbol: Ppp1cc
Name: protein phosphatase 1 catalytic subunit gamma
Description: Exhibits several functions, including lamin binding activity; protein C-terminus binding activity; and protein phosphatase 1 binding activity. Involved in neuron differentiation and positive regulation of glial cell proliferation. Localizes to several cellular components, including dendritic spine; glutamatergic synapse; and presynapse. Predicted to colocalize with nuclear chromosome, telomeric region. Biomarker of congestive heart failure. Orthologous to human PPP1CC (protein phosphatase 1 catalytic subunit gamma); PARTICIPATES IN calcium/calmodulin dependent kinase 2 signaling pathway; dopamine signaling pathway; glycogen biosynthetic pathway; INTERACTS WITH ammonium chloride; ampicillin; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: PP-1G; Ppp1cc1; protein phosphatase 1 catalytic subunit gamma isoform; protein phosphatase 1 catalytic subunit gamma isoform 1; Protein phosphatase 1 catalytic subunit gamma isoform 1 (possible existence of an alternative gene product Ppp1cc2); protein phosphatase 1, catalytic subunit, gamma isoform; protein phosphatase 1, catalytic subunit, gamma isozyme; protein phosphatase 1C catalytic subunit; protein serine-threonine phosphatase catalytic subunit PP-1b; serine/threonine-protein phosphatase PP1-gamma catalytic subunit
Orthologs:
Homo sapiens (human) : PPP1CC (protein phosphatase 1 catalytic subunit gamma)  HGNC  Alliance
Mus musculus (house mouse) : Ppp1cc (protein phosphatase 1 catalytic subunit gamma)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ppp1cc (protein phosphatase 1 catalytic subunit gamma)
Pan paniscus (bonobo/pygmy chimpanzee) : PPP1CC (protein phosphatase 1 catalytic subunit gamma)
Canis lupus familiaris (dog) : PPP1CC (protein phosphatase 1 catalytic subunit gamma)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ppp1cc (protein phosphatase 1 catalytic subunit gamma)
Sus scrofa (pig) : PPP1CC (protein phosphatase 1 catalytic subunit gamma)
Chlorocebus sabaeus (African green monkey) : PPP1CC (protein phosphatase 1 catalytic subunit gamma)
Heterocephalus glaber (naked mole-rat) : Ppp1cc (protein phosphatase 1 catalytic subunit gamma)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01239,864,302 - 39,882,030 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1239,864,295 - 39,882,030 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01241,744,531 - 41,762,059 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41235,580,169 - 35,598,249 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11235,443,556 - 35,461,637 (-)NCBI
Celera1236,054,251 - 36,071,363 (-)NCBICelera
Cytogenetic Map12q16NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Candidate Gene Status
Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Ppp1cc
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3377
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.