1,1-dichloroethene decreases expression ISO RGD:1552999 6480464 vinylidene chloride results in decreased expression of PPP1R9A mRNA CTD PMID:26682919 1-naphthyl isothiocyanate increases expression EXP 6480464 1-Naphthylisothiocyanate results in increased expression of PPP1R9A mRNA CTD PMID:30723492 17alpha-ethynylestradiol increases expression EXP 6480464 Ethinyl Estradiol results in increased expression of PPP1R9A mRNA CTD PMID:29097150 17beta-estradiol multiple interactions ISO RGD:1350094 6480464 [Estradiol co-treated with TGFB1 protein] results in decreased expression of PPP1R9A mRNA CTD PMID:30165855 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:1552999 6480464 [TIPARP gene mutant form results in increased susceptibility to Tetrachlorodibenzodioxin] which results in increased expression of PPP1R9A mRNA CTD PMID:25975270 4-hydroxyphenyl retinamide decreases expression ISO RGD:1552999 6480464 Fenretinide results in decreased expression of PPP1R9A mRNA CTD PMID:28973697 5-(hydroxymethyl)cytosine multiple interactions ISO RGD:1552999 6480464 [bisphenol A results in decreased methylation of PPP1R9A intron] which results in decreased abundance of 5-hydroxymethylcytosine CTD PMID:30044229 aflatoxin B2 increases methylation ISO RGD:1350094 6480464 aflatoxin B2 results in increased methylation of PPP1R9A intron CTD PMID:30157460 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of PPP1R9A mRNA CTD PMID:16483693 antirheumatic drug increases expression ISO RGD:1350094 6480464 Antirheumatic Agents results in increased expression of PPP1R9A mRNA CTD PMID:24449571 benzo[a]pyrene affects expression ISO RGD:1350094 6480464 Benzo(a)pyrene affects the expression of PPP1R9A mRNA CTD PMID:21714911 benzo[a]pyrene decreases expression ISO RGD:1350094 6480464 Benzo(a)pyrene results in decreased expression of PPP1R9A mRNA CTD PMID:20106945 more ... benzo[a]pyrene diol epoxide I decreases expression ISO RGD:1350094 6480464 7 more ... CTD PMID:20018196 benzo[e]pyrene increases methylation ISO RGD:1350094 6480464 benzo(e)pyrene results in increased methylation of PPP1R9A intron CTD PMID:30157460 bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of PPP1R9A mRNA CTD PMID:25181051 bisphenol A multiple interactions ISO RGD:1552999 6480464 [bisphenol A results in decreased methylation of PPP1R9A intron] which results in decreased abundance of 5-hydroxymethylcytosine CTD PMID:30044229 bisphenol A increases methylation EXP 6480464 bisphenol A results in increased methylation of PPP1R9A gene CTD PMID:28505145 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of PPP1R9A mRNA CTD PMID:29097150 Brodifacoum increases expression EXP 6480464 bromfenacoum results in increased expression of PPP1R9A protein CTD PMID:28903499 butanal decreases expression ISO RGD:1350094 6480464 butyraldehyde results in decreased expression of PPP1R9A mRNA CTD PMID:26079696 carbon nanotube decreases expression ISO RGD:1552999 6480464 Nanotubes, Carbon analog results in decreased expression of PPP1R9A mRNA, Nanotubes, Carbon results in decreased expression of PPP1R9A mRNA CTD PMID:25554681 , PMID:25620056 choline multiple interactions ISO RGD:1552999 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of PPP1R9A mRNA CTD PMID:20938992 cisplatin multiple interactions ISO RGD:1350094 6480464 [Cisplatin co-treated with jinfukang] results in decreased expression of PPP1R9A mRNA CTD PMID:27392435 cisplatin decreases expression ISO RGD:1350094 6480464 Cisplatin results in decreased expression of PPP1R9A mRNA CTD PMID:27392435 cobalt dichloride decreases expression ISO RGD:1350094 6480464 cobaltous chloride results in decreased expression of PPP1R9A mRNA CTD PMID:19376846 cyclosporin A decreases expression ISO RGD:1350094 6480464 Cyclosporine results in decreased expression of PPP1R9A mRNA CTD PMID:25562108 dioxygen multiple interactions ISO RGD:1552999 6480464 [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of PPP1R9A mRNA CTD PMID:30529165 dorsomorphin multiple interactions ISO RGD:1350094 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 doxorubicin decreases expression ISO RGD:1350094 6480464 Doxorubicin results in decreased expression of PPP1R9A mRNA CTD PMID:29803840 elemental selenium multiple interactions ISO RGD:1350094 6480464 [Selenium co-treated with Vitamin E] results in decreased expression of PPP1R9A mRNA CTD PMID:19244175 elemental selenium decreases expression ISO RGD:1350094 6480464 Selenium results in decreased expression of PPP1R9A mRNA CTD PMID:19244175 endosulfan decreases expression EXP 6480464 Endosulfan results in decreased expression of PPP1R9A mRNA CTD PMID:29391264 entinostat decreases expression ISO RGD:1350094 6480464 entinostat results in decreased expression of PPP1R9A mRNA CTD PMID:26272509 , PMID:27188386 entinostat multiple interactions ISO RGD:1350094 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of PPP1R9A mRNA CTD PMID:27188386 ethanol affects splicing ISO RGD:1552999 6480464 Ethanol affects the splicing of PPP1R9A mRNA CTD PMID:30319688 folic acid multiple interactions ISO RGD:1552999 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of PPP1R9A mRNA CTD PMID:20938992 gentamycin decreases expression EXP 6480464 Gentamicins results in decreased expression of PPP1R9A mRNA CTD PMID:22061828 hydralazine multiple interactions ISO RGD:1350094 6480464 [Hydralazine co-treated with Valproic Acid] results in increased expression of PPP1R9A mRNA CTD PMID:17183730 L-methionine multiple interactions ISO RGD:1552999 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of PPP1R9A mRNA CTD PMID:20938992 latrunculin B affects localization EXP 6480464 latrunculin B affects the localization of PPP1R9A protein CTD PMID:12052877 menadione affects expression ISO RGD:1350094 6480464 Vitamin K 3 affects the expression of PPP1R9A mRNA CTD PMID:20044591 methamphetamine decreases expression EXP 6480464 Methamphetamine results in decreased expression of PPP1R9A mRNA CTD PMID:15644446 methapyrilene increases methylation ISO RGD:1350094 6480464 Methapyrilene results in increased methylation of PPP1R9A intron CTD PMID:30157460 methoxychlor increases methylation EXP 6480464 Methoxychlor results in increased methylation of PPP1R9A gene CTD PMID:23303685 methylmercury chloride decreases expression ISO RGD:1350094 6480464 methylmercuric chloride results in decreased expression of PPP1R9A mRNA CTD PMID:28001369 N-acetyl-beta-D-glucosamine decreases expression ISO RGD:1350094 6480464 Acetylglucosamine results in decreased expression of PPP1R9A mRNA CTD PMID:18047607 N-acetyl-D-glucosamine decreases expression ISO RGD:1350094 6480464 Acetylglucosamine results in decreased expression of PPP1R9A mRNA CTD PMID:18047607 N-nitrosodiethylamine multiple interactions EXP 6480464 [Phenobarbital co-treated with Diethylnitrosamine] results in increased expression of PPP1R9A protein CTD PMID:20935162 N-nitrosodiethylamine increases expression EXP 6480464 Diethylnitrosamine results in increased expression of PPP1R9A protein CTD PMID:20935162 nickel atom decreases expression ISO RGD:1350094 6480464 Nickel results in decreased expression of PPP1R9A mRNA CTD PMID:24768652 , PMID:25583101 paclitaxel decreases expression ISO RGD:1350094 6480464 Paclitaxel results in decreased expression of PPP1R9A mRNA CTD PMID:15000894 panobinostat multiple interactions ISO RGD:1350094 6480464 [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of PPP1R9A mRNA CTD PMID:27188386 panobinostat decreases expression ISO RGD:1350094 6480464 panobinostat results in decreased expression of PPP1R9A mRNA CTD PMID:26272509 paracetamol affects expression ISO RGD:1552999 6480464 Acetaminophen affects the expression of PPP1R9A mRNA CTD PMID:17562736 phenobarbital multiple interactions EXP 6480464 [Phenobarbital co-treated with Diethylnitrosamine] results in increased expression of PPP1R9A protein CTD PMID:20935162 phenobarbital affects expression ISO RGD:1552999 6480464 Phenobarbital affects the expression of PPP1R9A mRNA CTD PMID:23091169 phenyl acetate affects hydrolysis ISO RGD:1350094 6480464 PPP1R9A 3' UTR SNP affects the hydrolysis of phenyl acetate CTD PMID:20839225 phenylmercury acetate decreases expression ISO RGD:1350094 6480464 Phenylmercuric Acetate results in decreased expression of PPP1R9A mRNA CTD PMID:26272509 phenylmercury acetate multiple interactions ISO RGD:1350094 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of PPP1R9A mRNA CTD PMID:27188386 potassium chromate increases expression ISO RGD:1350094 6480464 potassium chromate(VI) results in increased expression of PPP1R9A mRNA CTD PMID:22714537 quercetin decreases expression ISO RGD:1350094 6480464 Quercetin results in decreased expression of PPP1R9A mRNA CTD PMID:21632981 rotenone decreases expression ISO RGD:1552999 6480464 Rotenone results in decreased expression of PPP1R9A mRNA CTD PMID:23186747 SB 431542 multiple interactions ISO RGD:1350094 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 selenium atom multiple interactions ISO RGD:1350094 6480464 [Selenium co-treated with Vitamin E] results in decreased expression of PPP1R9A mRNA CTD PMID:19244175 selenium atom decreases expression ISO RGD:1350094 6480464 Selenium results in decreased expression of PPP1R9A mRNA CTD PMID:19244175 sodium arsenate increases expression ISO RGD:1552999 6480464 sodium arsenate results in increased expression of PPP1R9A mRNA CTD PMID:21795629 sodium arsenite increases expression ISO RGD:1350094 6480464 sodium arsenite results in increased expression of PPP1R9A mRNA CTD PMID:22714537 sodium arsenite affects methylation ISO RGD:1350094 6480464 sodium arsenite affects the methylation of PPP1R9A gene CTD PMID:28589171 sulforaphane decreases expression ISO RGD:1552999 6480464 sulforafan results in decreased expression of PPP1R9A mRNA CTD PMID:30529165 testosterone enanthate affects expression ISO RGD:1350094 6480464 testosterone enanthate affects the expression of PPP1R9A mRNA CTD PMID:17440010 trichostatin A decreases expression ISO RGD:1350094 6480464 trichostatin A results in decreased expression of PPP1R9A mRNA CTD PMID:24935251 , PMID:26272509 trichostatin A multiple interactions ISO RGD:1350094 6480464 [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of PPP1R9A mRNA CTD PMID:27188386 trimellitic anhydride decreases expression ISO RGD:1552999 6480464 trimellitic anhydride results in decreased expression of PPP1R9A mRNA CTD PMID:19042947 valproic acid multiple interactions ISO RGD:1350094 6480464 [Hydralazine co-treated with Valproic Acid] results in increased expression of PPP1R9A mRNA more ... CTD PMID:17183730 , PMID:27188386 valproic acid affects splicing EXP 6480464 Valproic Acid affects the splicing of PPP1R9A mRNA CTD PMID:29427782 valproic acid decreases expression EXP 6480464 Valproic Acid results in decreased expression of PPP1R9A mRNA CTD PMID:29427782 valproic acid decreases expression ISO RGD:1350094 6480464 Valproic Acid results in decreased expression of PPP1R9A mRNA CTD PMID:23179753 more ... valproic acid affects expression ISO RGD:1350094 6480464 Valproic Acid affects the expression of PPP1R9A mRNA CTD PMID:25979313 valproic acid decreases methylation ISO RGD:1350094 6480464 Valproic Acid results in decreased methylation of PPP1R9A gene CTD PMID:29154799 vitamin E multiple interactions ISO RGD:1350094 6480464 [Selenium co-treated with Vitamin E] results in decreased expression of PPP1R9A mRNA CTD PMID:19244175 vitamin E decreases expression ISO RGD:1350094 6480464 Vitamin E results in decreased expression of PPP1R9A mRNA CTD PMID:19244175
Biological Process actin filament organization ISO RGD:1552999 1624291 UniProtKB:Q60875 (MGI:MGI:3583726 , PMID:15996550) RGD MGI:MGI:3583726 , PMID:15996550 actin filament organization IBA MGI:MGI:2387581 more ... 13792537 PMID:21873635 GO_Central aging IEP 10043798 RGD calcium-mediated signaling ISO RGD:1552999 1624291 MGI:MGI:4397456 (MGI:MGI:4397775 , PMID:17464283) RGD MGI:MGI:4397775 , PMID:17464283 calcium-mediated signaling IBA MGI:MGI:2387581 more ... 13792537 PMID:21873635 GO_Central cellular response to toxic substance IDA 1299363 latrunculin B RGD excitatory postsynaptic potential IMP 10043779 RGD modulation of chemical synaptic transmission ISO RGD:1552999 1624291 (MGI:MGI:3639803, PMID:16600521) RGD MGI:MGI:3639803 , PMID:16600521 negative regulation of long-term synaptic potentiation IMP 10002752 RGD negative regulation of spontaneous neurotransmitter secretion IMP 10002752 RGD negative regulation of stress fiber assembly IMP 1299363 RGD neuron development IEP 625592 RGD neuron projection development IDA 8554233 PMID:16525025 MGI neuron projection development IBA PANTHER:PTN000414425 , RGD:632280 13792537 PMID:21873635 GO_Central positive regulation of dendritic spine development IMP 1299363 RGD positive regulation of long-term synaptic depression IMP 10002752 RGD positive regulation of neuron projection development IMP 625592 RGD positive regulation of protein kinase activity IMP 8554053 RGD postsynaptic actin cytoskeleton organization IDA 10043779 PMID:15473970 SynGO postsynaptic actin cytoskeleton organization IMP 10043779 PMID:15473970 SynGO regulation of actin filament polymerization IMP 10043779 RGD regulation of dendritic spine morphogenesis IMP 10043779 RGD regulation of filopodium assembly IMP 1299363 RGD regulation of synapse assembly IMP 10043779 RGD regulation of synapse structural plasticity IMP 10043779 RGD Cellular Component actin cytoskeleton IDA 10002736 RGD actin cytoskeleton IBA PANTHER:PTN000414425 more ... 13792537 PMID:21873635 GO_Central cell junction IEA UniProtKB-KW:KW-0965 1600115 GO_REF:0000037 UniProt GO_REF:0000037 cortical actin cytoskeleton ISO RGD:1552999 1624291 (MGI:MGI:3583726, PMID:15996550) RGD MGI:MGI:3583726 , PMID:15996550 cortical actin cytoskeleton IEA UniProtKB:Q7TN74 , ensembl:ENSMUSP000000469061600115 GO_REF:0000107 Ensembl GO_REF:0000107 cytoplasm IBA PANTHER:PTN000414425 more ... 13792537 PMID:21873635 GO_Central cytoskeleton IDA 8554233 PMID:16525025 MGI cytosol IDA 625592 RGD dendrite IDA 10043779 ; 625592 RGD dendrite IBA PANTHER:PTN000414425 , RGD:632280 13792537 PMID:21873635 GO_Central dendritic spine ISO RGD:1552999 1624291 (MGI:MGI:3583726, PMID:15996550) RGD MGI:MGI:3583726 , PMID:15996550 dendritic spine IDA 10043779 RGD dendritic spine neck IDA 10043779 RGD filopodium ISO RGD:1552999 1624291 (MGI:MGI:3583726, PMID:15996550) RGD MGI:MGI:3583726 , PMID:15996550 filopodium IDA 10002752 ; 10043779 RGD glutamatergic synapse IDA 10043779 PMID:15473970 SynGO glutamatergic synapse IMP 10043779 PMID:15473970 SynGO growth cone IDA 8554233 PMID:16525025 MGI growth cone lamellipodium IDA 625592 RGD lamellipodium IDA 625592 RGD neuromuscular junction IDA 625592 RGD neuron projection IDA 10002736 RGD neuronal cell body IDA 625592 RGD postsynaptic actin cytoskeleton IDA 10043779 PMID:15473970 SynGO postsynaptic actin cytoskeleton IMP 10043779 PMID:15473970 SynGO postsynaptic density IDA 10043779 RGD postsynaptic density IBA PANTHER:PTN000414425 more ... 13792537 PMID:21873635 GO_Central synapse IDA 625592 RGD Molecular Function actin filament binding IDA 625592 PMID:9362513 WormBase actin filament binding IBA PANTHER:PTN000414425 more ... 13792537 PMID:21873635 GO_Central GTPase binding IDA 8554233 Rac3 RGD identical protein binding IPI RGD:632280 625592 homodimerization RGD ion channel binding IPI RGD:619787 10043786 RGD protein binding IPI RGD:621099 1299366 RGD protein binding IPI UniProtKB:P62136 13432348 PMID:20305656 IntAct protein binding IPI UniProtKB:P67999 8554053 PMID:9653190 IntAct protein binding IPI UniProtKB:P63088 8554111 PMID:18216290 IntAct protein binding IPI UniProtKB:P62142 8554111 PMID:18216290 IntAct protein binding IPI RGD:620445 10002736 RGD protein binding ISO RGD:1552999 1624291 UniProtKB:P41220 more ... RGD MGI:MGI:3583726 more ... protein binding ISO RGD:1350094 1624291 UniProtKB:P41220 (PMID:17464283) RGD PMID:17464283 protein binding IPI RGD:632281 625568 RGD protein C-terminus binding IPI RGD:620683 8554053 RGD protein C-terminus binding IPI RGD:1343622 1299366 RGD protein C-terminus binding IPI RGD:1344962 1299366 RGD protein domain specific binding IDA 10002736 Tgoln2 RGD protein kinase binding IPI RGD:620683 8554053 RGD protein phosphatase 1 binding IPI RGD:3377 10043787 RGD protein phosphatase 1 binding IDA 10002752 catalytic subunit RGD protein phosphatase 1 binding IPI RGD:3375 10002754 RGD protein-containing complex binding IPI RGD:3375 , RGD:3377 10002754 RGD
Gene-Chemical Interaction Annotations
