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Gene: Zcchc8 (zinc finger CCHC-type containing 8) Rattus norvegicus

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Symbol:

Zcchc8

Name:

zinc finger CCHC-type containing 8

RGD ID:

1309774

Description:

Predicted to enable RNA binding activity. Predicted to be involved in co-transcriptional lncRNA 3' end processing, cleavage and polyadenylation pathway and mRNA 3'-end processing. Predicted to be located in nuclear body. Predicted to be part of TRAMP complex and catalytic step 2 spliceosome. Orthologous to human ZCCHC8 (zinc finger CCHC-type containing 8); INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; 4,4'-sulfonyldiphenol.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

LOC288661; zinc finger CCHC domain-containing protein 8; zinc finger, CCHC domain containing 8

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	ZCCHC8 (zinc finger CCHC-type containing 8)	HGNC	Ensembl, Inparanoid, NCBI, OMA, OrthoDB, Panther, PhylomeDB
Mus musculus (house mouse):	Zcchc8 (zinc finger, CCHC domain containing 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Zcchc8 (zinc finger CCHC-type containing 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	ZCCHC8 (zinc finger CCHC-type containing 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	ZCCHC8 (zinc finger CCHC-type containing 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Zcchc8 (zinc finger CCHC-type containing 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	ZCCHC8 (zinc finger CCHC-type containing 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	ZCCHC8 (zinc finger CCHC-type containing 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Zcchc8 (zinc finger CCHC-type containing 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	RFC5 (replication factor C subunit 5)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	ZCCHC8 (zinc finger CCHC-type containing 8)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Zcchc8 (zinc finger, CCHC domain containing 8)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	zcchc8 (zinc finger, CCHC domain containing 8)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	Y34D9A.7	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG4622	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	ZK632.11	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	zcchc8	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	12	38,530,037 - 38,553,595 (+)	NCBI		GRCr8
mRatBN7.2	12	32,869,170 - 32,892,707 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	12	32,869,310 - 32,891,325 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	12	34,047,842 - 34,071,162 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	12	34,659,193 - 34,682,512 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	12	33,711,071 - 33,734,392 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	12	38,303,665 - 38,327,174 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	12	38,303,624 - 38,326,502 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	12	40,177,903 - 40,201,629 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	12	34,007,470 - 34,029,866 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	12	33,870,878 - 33,893,253 (+)	NCBI
Celera	12	34,554,787 - 34,576,874 (+)	NCBI		Celera
Cytogenetic Map	12	q16	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Zcchc8	Rat	acute myeloid leukemia		ISO	RGD:1320291	8554872	ClinVar Annotator: match by term: Inherited acute myeloid leukemia	ClinVar	PMID:25741868
Zcchc8	Rat	aplastic anemia		ISO	RGD:1320291	8554872	ClinVar Annotator: match by term: Inherited aplastic anemia	ClinVar	PMID:25741868\|PMID:28492532
Zcchc8	Rat	dyskeratosis congenita		ISO	RGD:1320291	8554872	ClinVar Annotator: match by term: Dyskeratosis congenita	ClinVar	PMID:25741868
Zcchc8	Rat	Pulmonary Fibrosis and/or Bone Marrow Failure Syndrome, Telomere-Related, 5		ISO	RGD:1320291	8554872	ClinVar Annotator: match by term: Pulmonary fibrosis and/or bone marrow failure, telomere-related, 5 \| ClinVar more ...	ClinVar	PMID:25741868\|PMID:28492532\|PMID:31488579
Zcchc8	Rat	short chain acyl-CoA dehydrogenase deficiency		ISO	RGD:1320291	8554872	ClinVar Annotator: match by term: Deficiency of butyryl-CoA dehydrogenase	ClinVar	PMID:28492532

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Zcchc8	Rat	intellectual disability		ISO	RGD:1320291	11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:21937992

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Zcchc8	Rat	Pulmonary Fibrosis and/or Bone Marrow Failure Syndrome, Telomere-Related, 5		ISO	RGD:1320291	7240710		OMIM

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Zcchc8	Rat	1,2-dimethylhydrazine	decreases expression	ISO	RGD:1320292	6480464	1,2-Dimethylhydrazine results in decreased expression of ZCCHC8 mRNA	CTD	PMID:22206623
Zcchc8	Rat	17beta-estradiol	decreases expression	ISO	RGD:1320292	6480464	Estradiol results in decreased expression of ZCCHC8 mRNA	CTD	PMID:39298647
Zcchc8	Rat	2,4-dinitrotoluene	affects expression	EXP		6480464	2,4-dinitrotoluene affects the expression of ZCCHC8 mRNA	CTD	PMID:21346803
Zcchc8	Rat	2,6-dinitrotoluene	affects expression	EXP		6480464	2,6-dinitrotoluene affects the expression of ZCCHC8 mRNA	CTD	PMID:21346803
Zcchc8	Rat	2-methylcholine	affects expression	ISO	RGD:1320291	6480464	beta-methylcholine affects the expression of ZCCHC8 mRNA	CTD	PMID:21179406
Zcchc8	Rat	4,4'-sulfonyldiphenol	decreases expression	ISO	RGD:1320292	6480464	bisphenol S results in decreased expression of ZCCHC8 mRNA	CTD	PMID:39298647
Zcchc8	Rat	4,4'-sulfonyldiphenol	multiple interactions	EXP		6480464	[bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of more ...	CTD	PMID:36041667
Zcchc8	Rat	acrylamide	increases expression	ISO	RGD:1320291	6480464	Acrylamide results in increased expression of ZCCHC8 mRNA	CTD	PMID:32763439
Zcchc8	Rat	aflatoxin B1	increases expression	ISO	RGD:1320292	6480464	Aflatoxin B1 results in increased expression of ZCCHC8 mRNA	CTD	PMID:19770486
Zcchc8	Rat	arsane	multiple interactions	ISO	RGD:1320291	6480464	[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of ZCCHC8 more ...	CTD	PMID:39836092
Zcchc8	Rat	arsenic atom	multiple interactions	ISO	RGD:1320291	6480464	[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of ZCCHC8 more ...	CTD	PMID:39836092
Zcchc8	Rat	benzo[a]pyrene	affects methylation	ISO	RGD:1320291	6480464	Benzo(a)pyrene affects the methylation of ZCCHC8 intron	CTD	PMID:30157460
Zcchc8	Rat	benzo[a]pyrene diol epoxide I	affects expression	ISO	RGD:1320291	6480464	7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide affects the expression of ZCCHC8 mRNA	CTD	PMID:20382639
Zcchc8	Rat	bisphenol A	increases expression	ISO	RGD:1320292	6480464	bisphenol A results in increased expression of ZCCHC8 mRNA	CTD	PMID:26063408
Zcchc8	Rat	bisphenol A	multiple interactions	EXP		6480464	[bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of more ...	CTD	PMID:36041667
Zcchc8	Rat	bisphenol A	increases methylation	ISO	RGD:1320291	6480464	bisphenol A results in increased methylation of ZCCHC8 gene	CTD	PMID:31601247
Zcchc8	Rat	bisphenol A	decreases expression	EXP		6480464	bisphenol A results in decreased expression of ZCCHC8 mRNA	CTD	PMID:30816183
Zcchc8	Rat	bisphenol F	decreases expression	ISO	RGD:1320292	6480464	bisphenol F results in decreased expression of ZCCHC8 mRNA	CTD	PMID:38685157
Zcchc8	Rat	bisphenol F	multiple interactions	EXP		6480464	[bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of more ...	CTD	PMID:36041667
Zcchc8	Rat	caffeine	affects phosphorylation	ISO	RGD:1320291	6480464	Caffeine affects the phosphorylation of ZCCHC8 protein	CTD	PMID:35688186
Zcchc8	Rat	carbamazepine	affects expression	ISO	RGD:1320291	6480464	Carbamazepine affects the expression of ZCCHC8 mRNA	CTD	PMID:25979313
Zcchc8	Rat	CGP 52608	multiple interactions	ISO	RGD:1320291	6480464	CGP 52608 promotes the reaction [RORA protein binds to ZCCHC8 gene]	CTD	PMID:28238834
Zcchc8	Rat	cobalt dichloride	increases expression	ISO	RGD:1320291	6480464	cobaltous chloride results in increased expression of ZCCHC8 mRNA	CTD	PMID:19376846
Zcchc8	Rat	copper(II) sulfate	increases expression	ISO	RGD:1320291	6480464	Copper Sulfate results in increased expression of ZCCHC8 mRNA	CTD	PMID:19549813
Zcchc8	Rat	Cuprizon	increases expression	EXP		6480464	Cuprizone results in increased expression of ZCCHC8 mRNA	CTD	PMID:26577399
Zcchc8	Rat	cyclosporin A	increases expression	ISO	RGD:1320291	6480464	Cyclosporine results in increased expression of ZCCHC8 mRNA	CTD	PMID:20106945\|PMID:25562108
Zcchc8	Rat	decabromodiphenyl ether	decreases expression	EXP		6480464	decabromobiphenyl ether results in decreased expression of ZCCHC8 mRNA	CTD	PMID:23914054
Zcchc8	Rat	Dibutyl phosphate	affects expression	ISO	RGD:1320291	6480464	di-n-butylphosphoric acid affects the expression of ZCCHC8 mRNA	CTD	PMID:37042841
Zcchc8	Rat	diuron	decreases expression	ISO	RGD:1320291	6480464	Diuron results in decreased expression of ZCCHC8 mRNA	CTD	PMID:35967413
Zcchc8	Rat	elemental selenium	decreases expression	ISO	RGD:1320291	6480464	Selenium results in decreased expression of ZCCHC8 mRNA	CTD	PMID:19244175
Zcchc8	Rat	enzyme inhibitor	multiple interactions	ISO	RGD:1320291	6480464	[Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation more ...	CTD	PMID:23301498
Zcchc8	Rat	FR900359	affects phosphorylation	ISO	RGD:1320291	6480464	FR900359 affects the phosphorylation of ZCCHC8 protein	CTD	PMID:37730182
Zcchc8	Rat	hydrogen peroxide	multiple interactions	ISO	RGD:1320292	6480464	[Hydrogen Peroxide co-treated with N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride] results in increased phosphorylation of ZCCHC8 protein	CTD	PMID:31494107
Zcchc8	Rat	ivermectin	decreases expression	ISO	RGD:1320291	6480464	Ivermectin results in decreased expression of ZCCHC8 protein	CTD	PMID:32959892
Zcchc8	Rat	lead diacetate	decreases expression	ISO	RGD:1320292	6480464	lead acetate results in decreased expression of ZCCHC8 mRNA	CTD	PMID:21829687
Zcchc8	Rat	manganese atom	multiple interactions	ISO	RGD:1320291	6480464	[manganese chloride results in increased abundance of Manganese] which results in increased expression of ZCCHC8 more ...	CTD	PMID:39836092
Zcchc8	Rat	manganese(0)	multiple interactions	ISO	RGD:1320291	6480464	[manganese chloride results in increased abundance of Manganese] which results in increased expression of ZCCHC8 more ...	CTD	PMID:39836092
Zcchc8	Rat	manganese(II) chloride	multiple interactions	ISO	RGD:1320291	6480464	[manganese chloride results in increased abundance of Manganese] which results in increased expression of ZCCHC8 more ...	CTD	PMID:39836092
Zcchc8	Rat	methotrexate	increases expression	ISO	RGD:1320291	6480464	Methotrexate results in increased expression of ZCCHC8 mRNA	CTD	PMID:17400583
Zcchc8	Rat	methyl methanesulfonate	increases expression	ISO	RGD:1320291	6480464	Methyl Methanesulfonate results in increased expression of ZCCHC8 mRNA	CTD	PMID:23649840
Zcchc8	Rat	N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine	decreases expression	ISO	RGD:1320291	6480464	N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of ZCCHC8 mRNA	CTD	PMID:12756304
Zcchc8	Rat	paracetamol	increases expression	ISO	RGD:1320291	6480464	Acetaminophen results in increased expression of ZCCHC8 mRNA	CTD	PMID:22230336
Zcchc8	Rat	selenium atom	decreases expression	ISO	RGD:1320291	6480464	Selenium results in decreased expression of ZCCHC8 mRNA	CTD	PMID:19244175
Zcchc8	Rat	silver atom	increases expression	ISO	RGD:1320291	6480464	Silver results in increased expression of ZCCHC8 mRNA	CTD	PMID:26014281
Zcchc8	Rat	silver(0)	increases expression	ISO	RGD:1320291	6480464	Silver results in increased expression of ZCCHC8 mRNA	CTD	PMID:26014281
Zcchc8	Rat	sodium arsenite	multiple interactions	ISO	RGD:1320291	6480464	[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of ZCCHC8 more ...	CTD	PMID:39836092
Zcchc8	Rat	temozolomide	increases expression	ISO	RGD:1320291	6480464	Temozolomide results in increased expression of ZCCHC8 mRNA	CTD	PMID:31758290
Zcchc8	Rat	titanium dioxide	decreases expression	ISO	RGD:1320292	6480464	titanium dioxide results in decreased expression of ZCCHC8 mRNA	CTD	PMID:29264374
Zcchc8	Rat	titanium dioxide	decreases methylation	ISO	RGD:1320292	6480464	titanium dioxide results in decreased methylation of ZCCHC8 gene	CTD	PMID:35295148
Zcchc8	Rat	trichostatin A	affects expression	ISO	RGD:1320291	6480464	trichostatin A affects the expression of ZCCHC8 mRNA	CTD	PMID:28542535
Zcchc8	Rat	troglitazone	decreases expression	ISO	RGD:1320292	6480464	troglitazone results in decreased expression of ZCCHC8 mRNA	CTD	PMID:28973697
Zcchc8	Rat	valproic acid	decreases expression	ISO	RGD:1320291	6480464	Valproic Acid results in decreased expression of ZCCHC8 mRNA	CTD	PMID:23179753\|PMID:28001369
Zcchc8	Rat	valproic acid	affects expression	ISO	RGD:1320291	6480464	Valproic Acid affects the expression of ZCCHC8 mRNA	CTD	PMID:25979313
Zcchc8	Rat	vinclozolin	affects expression	EXP		6480464	vinclozolin affects the expression of ZCCHC8 mRNA	CTD	PMID:19015723
Zcchc8	Rat	vitamin E	decreases expression	ISO	RGD:1320291	6480464	Vitamin E results in decreased expression of ZCCHC8 mRNA	CTD	PMID:19244175

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Zcchc8	Rat	co-transcriptional lncRNA 3' end processing, cleavage and polyadenylation pathway	involved_in	ISO	RGD:1320291	1624291	PMID:31488579	RGD	PMID:31488579
Zcchc8	Rat	co-transcriptional lncRNA 3' end processing, cleavage and polyadenylation pathway	involved_in	IEA	UniProtKB:Q6NZY4\|ensembl:ENSP00000488055	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Zcchc8	Rat	mRNA 3'-end processing	involved_in	ISO	RGD:1320291	1624291	PMID:31488579	RGD	PMID:31488579
Zcchc8	Rat	mRNA 3'-end processing	involved_in	IEA	UniProtKB:Q6NZY4\|ensembl:ENSP00000488055	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Zcchc8	Rat	RNA processing	involved_in	IBA	PANTHER:PTN000330129\|UniProtKB:Q6NZY4	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Zcchc8	Rat	catalytic step 2 spliceosome	part_of	ISO	RGD:1320291	1624291	PMID:11991638	RGD	PMID:11991638
Zcchc8	Rat	catalytic step 2 spliceosome	part_of	IBA	PANTHER:PTN000330129\|UniProtKB:Q6NZY4	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Zcchc8	Rat	catalytic step 2 spliceosome	part_of	IEA	UniProtKB:Q6NZY4\|ensembl:ENSP00000488055	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Zcchc8	Rat	nuclear body	located_in	IEA	UniProtKB:Q6NZY4\|ensembl:ENSP00000488055	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Zcchc8	Rat	nuclear body	located_in	ISO	RGD:1320291\|UniProtKB:Q6NZY4-1	1624291		RGD	GO_REF:0000052
Zcchc8	Rat	nucleolus	NOT\|located_in	ISO	RGD:1320291	1624291	PMID:21855801	RGD	PMID:21855801
Zcchc8	Rat	nucleoplasm	located_in	ISO	RGD:1320291\|UniProtKB:Q6NZY4-1\|UniProtKB:Q6NZY4-2	1624291		RGD	GO_REF:0000052
Zcchc8	Rat	nucleoplasm	located_in	IEA	UniProtKB:Q6NZY4\|ensembl:ENSP00000488055	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Zcchc8	Rat	nucleoplasm	located_in	IEA	UniProtKB-SubCell:SL-0190	1600115	GO_REF:0000044	UniProt	GO_REF:0000044
Zcchc8	Rat	nucleoplasm	located_in	ISO	RGD:1320291	1624291	PMID:16263084	RGD	PMID:16263084
Zcchc8	Rat	nucleus	located_in	IEA	UniProtKB-KW:KW-0539	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Zcchc8	Rat	nucleus	located_in	IEA	UniProtKB:Q6NZY4\|ensembl:ENSP00000488055	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Zcchc8	Rat	nucleus	located_in	ISO	RGD:1320291	1624291	PMID:21855801	RGD	PMID:21855801
Zcchc8	Rat	TRAMP complex	part_of	ISO	RGD:1320291	1624291	PMID:21855801	RGD	PMID:21855801
Zcchc8	Rat	TRAMP complex	part_of	IEA	UniProtKB:Q6NZY4\|ensembl:ENSP00000488055	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Zcchc8	Rat	metal ion binding	enables	IEA	UniProtKB-KW:KW-0479	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Zcchc8	Rat	nucleic acid binding	enables	IEA	InterPro:IPR001878	1600115	GO_REF:0000002	InterPro	GO_REF:0000002
Zcchc8	Rat	protein binding	enables	ISO	RGD:1320291	1624291	UniProtKB:P38398\|UniProtKB:P42285\|UniProtKB:P57052\|UniProtKB:Q9CQT2\|UniProtKB:Q9Y580 PMID:16263084, PMID:17525332, PMID:25525152, PMID:25578728, PMID:26496610, PMID:27871484, PMID:27905398, PMID:28514442, PMID:29844170, PMID:31358741, PMID:33961781, PMID:35914814	RGD	PMID:16263084\|PMID:17525332\|PMID:25525152\|PMID:25578728\|PMID:26496610\|PMID:27871484\|PMID:27905398\|PMID:28514442\|PMID:29844170\|PMID:31358741\|PMID:33961781\|PMID:35914814
Zcchc8	Rat	RNA binding	enables	ISO	RGD:1320291	1624291	PMID:31488579	RGD	PMID:31488579
Zcchc8	Rat	RNA binding	enables	IEA	UniProtKB:Q6NZY4\|ensembl:ENSP00000488055	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Zcchc8	Rat	RNA binding	enables	IBA	PANTHER:PTN000330129\|UniProtKB:Q6NZY4	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Zcchc8	Rat	zinc ion binding	enables	IEA	InterPro:IPR001878	1600115	GO_REF:0000002	InterPro	GO_REF:0000002
Zcchc8	Rat	zinc ion binding	enables	IEA	UniProtKB-KW:KW-0863	1600115	GO_REF:0000043	UniProt	GO_REF:0000043

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
3.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

PMID:11991638	PMID:16263084	PMID:21855801	PMID:22658674	PMID:31488579

Zcchc8
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	12	38,530,037 - 38,553,595 (+)	NCBI		GRCr8
mRatBN7.2	12	32,869,170 - 32,892,707 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	12	32,869,310 - 32,891,325 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	12	34,047,842 - 34,071,162 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	12	34,659,193 - 34,682,512 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	12	33,711,071 - 33,734,392 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	12	38,303,665 - 38,327,174 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	12	38,303,624 - 38,326,502 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	12	40,177,903 - 40,201,629 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	12	34,007,470 - 34,029,866 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	12	33,870,878 - 33,893,253 (+)	NCBI
Celera	12	34,554,787 - 34,576,874 (+)	NCBI		Celera
Cytogenetic Map	12	q16	NCBI

ZCCHC8
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	12	122,471,600 - 122,500,932 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	12	122,471,600 - 122,500,932 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	12	122,956,147 - 122,985,479 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	12	121,523,388 - 121,551,471 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	12	121,482,314 - 121,510,398	NCBI
Celera	12	122,549,115 - 122,577,860 (-)	NCBI		Celera
Cytogenetic Map	12	q24.31	NCBI
HuRef	12	119,917,061 - 119,946,428 (-)	NCBI		HuRef
CHM1_1	12	122,924,443 - 122,953,852 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	12	122,467,426 - 122,496,741 (-)	NCBI		T2T-CHM13v2.0

Zcchc8
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	5	123,836,365 - 123,859,107 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	5	123,836,357 - 123,859,163 (-)	Ensembl		GRCm39 Ensembl
GRCm38	5	123,698,302 - 123,721,044 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	5	123,698,294 - 123,721,100 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	5	124,148,311 - 124,171,053 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	5	123,960,412 - 123,981,558 (-)	NCBI		MGSCv36	mm8
Celera	5	120,774,733 - 120,797,566 (-)	NCBI		Celera
Cytogenetic Map	5	F	NCBI
cM Map	5	63.14	NCBI

Zcchc8
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955482	6,163,990 - 6,184,967 (+)	NCBI	ChiLan1.0	ChiLan1.0

ZCCHC8
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	10	130,565,168 - 130,593,166 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	12	130,561,544 - 130,589,540 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	12	120,075,830 - 120,103,820 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	12	124,297,279 - 124,325,110 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	12	124,297,279 - 124,325,110 (-)	Ensembl	panpan1.1		panPan2

ZCCHC8
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	26	6,895,873 - 6,927,262 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	26	6,895,904 - 6,926,484 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	26	7,055,718 - 7,087,455 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	26	7,146,830 - 7,178,682 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	26	7,146,852 - 7,178,679 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	26	7,077,116 - 7,109,143 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	26	7,170,594 - 7,202,146 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	26	7,125,675 - 7,157,475 (+)	NCBI		UU_Cfam_GSD_1.0

Zcchc8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	157,393,740 - 157,420,553 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936558	2,058,928 - 2,084,639 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936558	2,058,513 - 2,085,686 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ZCCHC8
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	14	30,264,291 - 30,288,658 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	14	30,264,397 - 30,288,068 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	14	31,881,632 - 31,903,948 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ZCCHC8
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	11	117,810,007 - 117,839,916 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666037	127,484,349 - 127,514,079 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Zcchc8
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624747	22,615,310 - 22,639,076 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants in Zcchc8
163 total Variants

Assembly: Rnor_5.0

Chromosome	Start Pos	End Pos	Reference Nucleotide	Variant Nucleotide	Variant Type	Strain	Variant Page
12	40197939	40197940	G	A	snv	BUF/MNa (KyushuU)	View more Information

Predicted Target Of

	Summary Value
Count of predictions:	288
Count of miRNA genes:	184
Interacting mature miRNAs:	210
Transcripts:	ENSRNOT00000001668
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
631560	Apr1	Acute phase response QTL 1	6.1		orosomucoid 1 amount (VT:0010541)	plasma orosomucoid 1 level (CMO:0001467)	12	19144362	46669029	Rat
8552964	Pigfal17	Plasma insulin-like growth factor 1 level QTL 17	3.5		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	12	5564495	46669029	Rat
8693635	Alc28	Alcohol consumption QTL 28	2.7	0.439	drinking behavior trait (VT:0001422)	calculated ethanol drink intake rate (CMO:0001615)	12	23081340	44726024	Rat
61324	Eae5	Experimental allergic encephalomyelitis QTL 5	14		nervous system integrity trait (VT:0010566)	percentage of study population developing relapsing-remitting experimental autoimmune encephalomyelitis during a period of time (CMO:0001402)	12	19610870	46669029	Rat
9590147	Scort7	Serum corticosterone level QTL 7	13.61	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	12	1	42110980	Rat
1549829	Scl48	Serum cholesterol level QTL 48	5		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	12	9603277	46669029	Rat
737822	Alc10	Alcohol consumption QTL 10	2.2		consumption behavior trait (VT:0002069)	ethanol drink intake rate (CMO:0001407)	12	19610870	40218516	Rat
2293684	Bmd26	Bone mineral density QTL 26	4.4	0.0002	femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	12	15872653	32974238	Rat
70169	Eae13	Experimental allergic encephalomyelitis QTL 13		0.032	nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)	12	24139202	36638073	Rat
1600386	Calcic2	Intracellular calcium level QTL 2		0.001	platelet physiology trait (VT:0005464)	platelet intracellular calcium level (CMO:0000922)	12	28064433	46669029	Rat
1302792	Scl21	Serum cholesterol level QTL 21	3.8	0.0011	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	12	7196730	46669029	Rat
1556747	Calcic1	Intracellular calcium level QTL 1		3.6	platelet calcium amount (VT:0010500)	platelet intracellular calcium level (CMO:0000922)	12	28064433	40130419	Rat
631829	Alc6	Alcohol consumption QTL 6	4.7		consumption behavior trait (VT:0002069)	ethanol drink intake rate (CMO:0001407)	12	28607526	37691617	Rat
8693658	Alc33	Alcohol consumption QTL 33	2.1	0.68	drinking behavior trait (VT:0001422)	calculated ethanol drink intake rate (CMO:0001615)	12	23081340	43551788	Rat
1598855	Bp294	Blood pressure QTL 294	3.5		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	12	1	34851688	Rat
1331761	Bp218	Blood pressure QTL 218	2.973		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	12	11073825	45055165	Rat
8694179	Bw150	Body weight QTL 150	2.9	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	12	1	42110980	Rat
7411545	Bw128	Body weight QTL 128	5.2	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	12	1	42110980	Rat
7411547	Bw129	Body weight QTL 129		0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	6	5564495	46669029	Rat
737979	Pia22	Pristane induced arthritis QTL 22	53.1		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	12	1	44465750	Rat
1298081	Cia25	Collagen induced arthritis QTL 25	4.7		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	12	19610889	35682913	Rat
2300186	Bmd59	Bone mineral density QTL 59	7.1	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	12	10474137	46669029	Rat
7411660	Foco28	Food consumption QTL 28	10.9	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	1	42110980	Rat
70213	Niddm27	Non-insulin dependent diabetes mellitus QTL 27	3.72		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	12	19835789	38193007	Rat
7411641	Foco19	Food consumption QTL 19	27.7	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	5564495	46669029	Rat
7411643	Foco20	Food consumption QTL 20		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	20328819	46669029	Rat
5684888	Pia42	Pristane induced arthritis QTL 42			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	12	19610870	42828880	Rat
1549912	Bp268	Blood pressure QTL 268			arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	10	13182736	46669029	Rat
2302060	Pia37	Pristane induced arthritis QTL 37	6.1	0.001	blood immunoglobulin amount (VT:0002460)	serum immunoglobulin G1 level (CMO:0002115)	12	13198157	46669029	Rat
1641928	Alcrsp5	Alcohol response QTL 5			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	12	12812385	46669029	Rat
1300162	Bp188	Blood pressure QTL 188	3.19		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	12	32103174	45899022	Rat
8552912	Pigfal6	Plasma insulin-like growth factor 1 level QTL 6	5		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	12	5564498	46669029	Rat
10059594	Kidm46	Kidney mass QTL 46	3.79	0.025	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	12	6107579	46669029	Rat
9590086	Insglur6	Insulin/glucose ratio QTL 6	18.97	0.001	blood insulin amount (VT:0001560)	calculated plasma insulin level (CMO:0002170)	12	1	42110980	Rat
8552918	Pigfal7	Plasma insulin-like growth factor 1 level QTL 7			blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	12	5564495	46669029	Rat
1549902	Bp269	Blood pressure QTL 269			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	12	13182736	46669029	Rat
61404	Bw120	Body weight QTL 120	5.1		body mass (VT:0001259)	body mass index (BMI) (CMO:0000105)	12	12351619	46669029	Rat
1300175	Cm5	Cardiac mass QTL 5	3.78		heart mass (VT:0007028)	heart left ventricle weight to body weight ratio (CMO:0000530)	12	28064433	45899022	Rat
1331787	Rf41	Renal function QTL 41	2.998		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal blood flow rate (CMO:0001168)	12	28064557	40218380	Rat
2293699	Bss49	Bone structure and strength QTL 49	5.61	0.0001	lumbar vertebra size trait (VT:0010518)	lumbar vertebra trabecular cross-sectional area (CMO:0001692)	12	10474137	46669029	Rat
634351	Apr5	Acute phase response QTL 5	6.7		blood interleukin-6 amount (VT:0008595)	plasma interleukin-6 level (CMO:0001927)	12	1	44503507	Rat
634350	Apr4	Acute phase response QTL 4	6		orosomucoid 1 amount (VT:0010541)	plasma orosomucoid 1 level (CMO:0001467)	12	1172005	46172005	Rat
7387292	Kidm42	Kidney mass QTL 42	3.03	0.0004	kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	12	1	36247923	Rat
61421	Cia12	Collagen induced arthritis QTL 12	4.6		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	12	13635523	35682913	Rat
2303569	Gluco44	Glucose level QTL 44	2		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	12	12812385	46669029	Rat
7411586	Foco5	Food consumption QTL 5	5.4	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	1	42110980	Rat
2303575	Insul14	Insulin level QTL 14	4		blood insulin amount (VT:0001560)	blood insulin level (CMO:0000349)	12	1	42450532	Rat
7411588	Foco6	Food consumption QTL 6		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	5564495	46669029	Rat
2302042	Pia38	Pristane induced arthritis QTL 38	3.5	0.001	blood immunoglobulin amount (VT:0002460)	serum immunoglobulin G1 level (CMO:0002115)	12	1	44503507	Rat
7411595	Foco9	Food consumption QTL 9	4	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	1	42110980	Rat
7411597	Foco10	Food consumption QTL 10		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	5564495	46669029	Rat
631543	Bp83	Blood pressure QTL 83	5.8		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	12	15550826	38478808	Rat

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	91	90	59	25	59	6	218	97	93	45	60	31


RefSeq Transcripts	NM_001400968	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006249334	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039089237	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039089238	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039089240	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063271178	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063271179	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC117299	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473973	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000012	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000001668 ⟹ ENSRNOP00000001668

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	12	32,869,310 - 32,891,325 (+)	Ensembl
Rnor_6.0 Ensembl	12	38,303,624 - 38,326,502 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000098796 ⟹ ENSRNOP00000080646

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	12	32,869,310 - 32,891,325 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000100518 ⟹ ENSRNOP00000091188

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	12	32,869,371 - 32,891,251 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000108167 ⟹ ENSRNOP00000095166

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	12	32,869,310 - 32,891,325 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000118220 ⟹ ENSRNOP00000080224

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	12	32,869,310 - 32,891,325 (+)	Ensembl

RefSeq Acc Id:

NM_001400968 ⟹ NP_001387897

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	38,530,241 - 38,553,595 (+)	NCBI
mRatBN7.2	12	32,869,351 - 32,892,707 (+)	NCBI

RefSeq Acc Id:

XM_006249334 ⟹ XP_006249396

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	38,530,065 - 38,553,595 (+)	NCBI
mRatBN7.2	12	32,869,171 - 32,892,707 (+)	NCBI
Rnor_6.0	12	38,303,665 - 38,327,174 (+)	NCBI
Rnor_5.0	12	40,177,903 - 40,201,629 (+)	NCBI

Sequence:

show sequence

GGACCCAGTCGGAAGGAGGCATGAGGGAGGCCTTGGCATTCTGGGAGTTGTAGTCTCCGGCCAGGTCCCGCCCCTAGACGGCTTTGGAGGCCTGTGTGTGGAGAAAAGCCTCTAGGGAGAGCGGTGCT
GCCCTACAACCTTCGCACCCTGCCCTCGAATCTTTCCCACAATCCAAAATGGCGGCCGGTGTGGATTTTGGCGACCTAGAGCTATTCGAGGCGTTTGATCCTCAAGAGGAGTCGACCCCGAAGCCCGT
TCACACCCGCTTCAAGGACGACGAGGAGGAAGACGACGACGACGATGAGAATGGGGTGGGTGACGCGGAACTGCAGGAGCAGCTTCGGCGCTGTGAGGAAACCATCGAGCAACTCCGCGCCGAGAATC
AAGAACTTAAAAGAAAGTTGAACATTCTGACAAGACCCAGTGGCATACTGGTGAGCAATACTAAGATAGATGGACCGTTATTACAAATTCTCTTTATGAACAATGCTATTTCAAAGCAATACCACCAA
GAAATAGAGGAGTTTGTATCAAACTTAGTAAAACGATTTGAGGAACAGCAAAAAAATGACGTGGAAAAGACTTCCTTCAGCCTTTTACCCCAGCCATCCAGTGTTATGTTGGAAGAGGACCGTAAAGT
GGAAGAATCGTGTGCCATTAAAAACAACAAGGAAGCTTTTAGTGTTGTAGGAAGTGTCCTGTATTTTACTAATTTTTGCCTTGATAAATTGGGGCAACCGCTACTAAATGAAAACCCTCAGCTTACGG
AAGGATGGGAAATCCCCAAGTACCAGCAAGTCTTCAGCCACATTGTTTCTCTAGAAGGGCAAGAAATGCAAGTAAAGGCGAAAAGGCCGAAGCCTCACTGTTTCAACTGTGGTTCTGAAGAGCACCAG
ATGAAGGAGTGCCCAATGCCTCGGAATGCTGCTCGAATAAGTGAGAAGAGAAAGGAGTACATGGACGCCTGTGGCGAGGCGAACAGTCAGAGTTTTCAGCAGCGCTACCATGCAGAAGAAGTAGAAGA
GAGATTTGGAAGATTCAAGCCAGGAGTTATTAGTGAGGAACTTCAAGATGCACTGGGTGTGACAGACAAGAGTCTTCCCCCTTTCATCTACCGGATGCGCCAGCTGGGCTACCCACCAGGCTGGCTCA
AGGAGGCTGAATTGGAGACTTCAGGACTTGCACTCTATGATGGAAATGATGATGCTGATGGGGAAACAGAAACTGGAGAAATACAGAATAAAAATGTTACTTATGATCTCTCAAAATTGGTAAACTAT
CCAGGTTTTAACATATCTACTCCCAGAGGTATTCCAGATCCAAGCGTGAAGTCGAGCAGCAAGCGGTCTTCCTCTCAGTCCAGCCCTAACAGTCCAAAGAAGCAGCGGAGGGAGGGCAGCGCAGCAGC
CTCCCCTGCTGACATGGAGCTTGACTCAGATATAGAGATTCCACCTGGTTCTCAGAGCAGCAAAGCATTTCAGTTTCAACCACCATTGCCTCCTGGCACACCTCCTCCTCTGCCACAGGGAACACCTC
CACCTCTCTTCACTCCTCCACTCCCTAAGGGAACCCCGCCACTGACTCCCAGTGACTCTCCCCAGCCGCGACCCACAGCCTCAGGCGTGGATGAGGATGCCCTGACACTGGAGGAGCTTGAAGAGCAG
CAGAGGCAGATCTGGGCAGCCCTCCAGCAGGCCGAGGGAGCGAACAGTGACTCCGATGTTCCCATGGACACACCTTTAACTGGAAACTCAGTGGCCTCCTCCCCTTGTCCAAACGAGTTTGACCTCCG
TGTCCCAGAAGGAAGGGCCCTGGAAAAGCCAGTGCTGGCCGAGCCTGACACAGCCTCGCCTGAGCCCTCCTGCAGCCCAGCCGCCGAGGCAGCAGTGCTCTCTCAGAAAGAAGAGGGCGTCTCCGCAG
AGGGGGACCCTGGAGATGGTCTTCTTGACAATGGCGGTGTGTTGAACATTAGCAACGGAGGCAACCATTTGGACACCCGGCCTCCGACAGCCTCAAAAACCCATAGCCCAGTACCTGACATGAGCAAG
TTTGCTCATGGAATAACACCCTTTGAGTTTGAGAACATGGCTGAATCCACCGGAATGTACCTCAGGATAAGAAACCTGTTAAAGAATTCACCCCGAAATCAGCAGAAAAACAAGAAGACTTCTGAGTG
AGCCCCTGCCGTAGCACTGGCTGCCAAGTGATCTGCAGCCCTGCCTGTCCCACCAGACCGGGACCAGGTGACCCATTTGTCCTCCCCTTTCAGAATCTGCCCGTGTGTAACTGATGTCAGCTCAAGCC
TGTTTTACCTAATGAAAGACTGGGCCTGTGAGCTTGCTGCTGTATTCTCACTGACAACAACCAGGGCGTGCGGGAGCTGGGTCACAGATGCTTGTCTCATCGTGAGTGTCTGTCAAGAGTGAGGTTTT
TTTTTAATGTCTTTTTGTAAATTGTTTCTACATTTTGCTATTATCCTGTATATATAAGCTTAATATATCACTTTTTAAAAGAAAATCCTAACAATTTTAAATTCACATTTCAATTTCCACAACCAAAT
GAGAATAATCAGGGCTGAGCAGCTTTATCCTGCTTGGGGTATTTTTGTAAGATTTTCATGCATGAATTTTAATAACACTTTTACTTTTTGTAATTTAATTATTCAAATATGCTTCCAATAAAGGTGTG
CTCACCTTTGCGTACAGAGGTTTAATAAATTAGTTTTCTTACACATGAACCAAGACTTTGGGTAGCTATGACTCACAGTTAAAATTGTTCTTCTAAACTTGGCTGAAAATTATGTGGTTGCAGTGAAA
CTGCATGTTTGGCTGCTGTAAGTGGATTCCAGCCTTACATATAATAATATAGAAACAGAATTGTCTAATTACTTTGGGGGGAAAATGGAGGTCAGCTAGCCTTCGTACACAGTAATATTGTGGATTCC
AGCTCGAAAATAGACCAGACCCGTACTGAGTGTGACTATCCTACGGAAGCGGGACCCTGCTCTGGGCGCTCTGAGTCTCTGCCAGGTCAAGTTTTGGAACACAGGGAGATCATGAGTTACAACTTAGT
CAGAGTAAGCTGCTCCCAGGCCAACAGAGGGCGCAAAAGGGAAGGATAAGGCCGCGCCAGGATACAGTGTTAAGGGCTGGCAGCTTCTTTGTCACCTGAGTTTTCAGTGCATTCCTCACAGGGTTTCC
ATGATGCTGTAACTGTGGGAAAGCAGCAGTCTTCCTAGGAAGCCCAAGACAAGGAAGGGAGGGCGTGGAGACACAGATAGGGGACCCTATCAACATTAAACACGCTTTCTTACCTCTCGGTGTTTTTC
CAGTGAGATGGTACATTGCTGTGTAGCCTAGGCTGGCCTCATTCACAATCTTCCTGATGCTACCTACTGCTGAGGTTGCAGGCAAGATGACATGGTTCTTTTTCAAAAACATTTATGGGGGTGGGGGG
CATTCCTTGGCATGGGTACGGATGTTAGAAGACAATGCGTGGGGGGTCCATGTTATGTTCTCTTGTCAATGTATGTCCTCATCAAGCACCTTTACCCAATGGGCCAGCCTGAAGGTGACATTGAACTT
GTTCGTCTTCCTGATTCCTGTTGACGGGTGTGCACTACCCTTCCCAGCAGCTCAGGAGCCACCCAGAACATTGTACGTGTGCTAGGCAAATACCACCAACCACACCACTTCCCCGCCCGGAGACCTAC
GGGATTCTGGAAGTGTCAAACTTCCACTAGAGACTTTAGATTTCTAAATCAGGAATTATTGTTTAGCCCTGTCTGGTGGCTTATGCCTGGAATCCTAGCCCTTGGGAGGCAGGCTGGTGGATCAGGAC
CAGCGTTGGTGACATAGCAGATTCAGTTAGCCTGAGCTACATGAGGTACTGCTAAAGGAAAGGGAAAAAAAAGTGTTTCTTTTAATACTGTATTGCCGGTATCTGCTGAATATTGAAACAGTCATTTC
CAGCACATACATACTCTGTTAAGCTATAGATTATACCATTTTTTCTTTATCGACTAGGTATTGCCTCTTCTTTTTGTTTTTGTTGTTTTTAAACGAATGTCTAAGACATAGATGCCTAGCTGTAAATA
AATTCAGATCTCTTGCCTCTGTA

hide sequence

RefSeq Acc Id:

XM_039089237 ⟹ XP_038945165

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	38,530,065 - 38,553,595 (+)	NCBI
mRatBN7.2	12	32,869,170 - 32,892,707 (+)	NCBI

RefSeq Acc Id:

XM_039089238 ⟹ XP_038945166

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	38,530,037 - 38,553,595 (+)	NCBI
mRatBN7.2	12	32,869,172 - 32,892,707 (+)	NCBI

RefSeq Acc Id:

XM_039089240 ⟹ XP_038945168

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	38,530,393 - 38,553,595 (+)	NCBI
mRatBN7.2	12	32,869,481 - 32,892,707 (+)	NCBI

RefSeq Acc Id:

XM_063271178 ⟹ XP_063127248

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	38,530,065 - 38,553,595 (+)	NCBI

RefSeq Acc Id:

XM_063271179 ⟹ XP_063127249

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	38,534,753 - 38,553,595 (+)	NCBI


Protein RefSeqs	NP_001387897	(Get FASTA)	NCBI Sequence Viewer
	XP_006249396	(Get FASTA)	NCBI Sequence Viewer
	XP_038945165	(Get FASTA)	NCBI Sequence Viewer
	XP_038945166	(Get FASTA)	NCBI Sequence Viewer
	XP_038945168	(Get FASTA)	NCBI Sequence Viewer
	XP_063127248	(Get FASTA)	NCBI Sequence Viewer
	XP_063127249	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDM13624	(Get FASTA)	NCBI Sequence Viewer
	EDM13625	(Get FASTA)	NCBI Sequence Viewer
	EDM13626	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000001668
	ENSRNOP00000001668.6
	ENSRNOP00000080224.1
	ENSRNOP00000080646
	ENSRNOP00000080646.1
	ENSRNOP00000091188.1
	ENSRNOP00000095166
	ENSRNOP00000095166.1

RefSeq Acc Id:	XP_006249396 ⟸ XM_006249334
- Peptide Label:	isoform X2
- UniProtKB:	A0A8I5ZR78 (UniProtKB/TrEMBL), A0A8I6GJE8 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAAGVDFGDLELFEAFDPQEESTPKPVHTRFKDDEEEDDDDDENGVGDAELQEQLRRCEETIEQLRAENQELKRKLNILTRPSGILVSNTKIDGPLLQILFMNNAISKQYHQEIEEFVSNLVKRFEEQ QKNDVEKTSFSLLPQPSSVMLEEDRKVEESCAIKNNKEAFSVVGSVLYFTNFCLDKLGQPLLNENPQLTEGWEIPKYQQVFSHIVSLEGQEMQVKAKRPKPHCFNCGSEEHQMKECPMPRNAARISEK RKEYMDACGEANSQSFQQRYHAEEVEERFGRFKPGVISEELQDALGVTDKSLPPFIYRMRQLGYPPGWLKEAELETSGLALYDGNDDADGETETGEIQNKNVTYDLSKLVNYPGFNISTPRGIPDPSV KSSSKRSSSQSSPNSPKKQRREGSAAASPADMELDSDIEIPPGSQSSKAFQFQPPLPPGTPPPLPQGTPPPLFTPPLPKGTPPLTPSDSPQPRPTASGVDEDALTLEELEEQQRQIWAALQQAEGANS DSDVPMDTPLTGNSVASSPCPNEFDLRVPEGRALEKPVLAEPDTASPEPSCSPAAEAAVLSQKEEGVSAEGDPGDGLLDNGGVLNISNGGNHLDTRPPTASKTHSPVPDMSKFAHGITPFEFENMAES TGMYLRIRNLLKNSPRNQQKNKKTSE hide sequence

Ensembl Acc Id:

ENSRNOP00000001668 ⟸ ENSRNOT00000001668

RefSeq Acc Id:	XP_038945165 ⟸ XM_039089237
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I6ASZ6 (UniProtKB/TrEMBL), A0A8I6GJE8 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038945166 ⟸ XM_039089238
- Peptide Label:	isoform X3
- UniProtKB:	A0A8I5ZQ77 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038945168 ⟸ XM_039089240
- Peptide Label:	isoform X5
- UniProtKB:	A6J137 (UniProtKB/TrEMBL)

Protein Domains

CCHC-type

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3ZUL8-F1-model_v2	AlphaFold	D3ZUL8	1-695	view protein structure

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

RGD ID:

13698627

Promoter ID:

EPDNEW_R9150

Type:

multiple initiation site

Name:

Zcchc8_1

Description:

zinc finger CCHC-type containing 8

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	12	38,303,828 - 38,303,888	EPDNEW

Database	Acc Id	Source(s)
BioCyc Gene	G2FUF-19321	BioCyc
Ensembl Genes	ENSRNOG00000001243	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000001668	ENTREZGENE
	ENSRNOT00000001668.8	UniProtKB/TrEMBL
	ENSRNOT00000098796	ENTREZGENE
	ENSRNOT00000098796.1	UniProtKB/TrEMBL
	ENSRNOT00000100518.1	UniProtKB/TrEMBL
	ENSRNOT00000108167	ENTREZGENE
	ENSRNOT00000108167.1	UniProtKB/TrEMBL
	ENSRNOT00000118220.1	UniProtKB/TrEMBL
InterPro	NEXT_complex_subunit_ZCCHC8	UniProtKB/TrEMBL
	PSP	UniProtKB/TrEMBL
	Znf_CCHC	UniProtKB/TrEMBL
NCBI Gene	288661	ENTREZGENE
PANTHER	ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 8	UniProtKB/TrEMBL
	ZINC FINGER, CCHC DOMAIN CONTAINING 8	UniProtKB/TrEMBL
Pfam	PSP	UniProtKB/TrEMBL
	zf-CCHC	UniProtKB/TrEMBL
PhenoGen	Zcchc8	PhenoGen
PROSITE	ZF_CCHC	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000001243	RatGTEx
SMART	PSP	UniProtKB/TrEMBL
	ZnF_C2HC	UniProtKB/TrEMBL
UniProt	A0A8I5ZQ77	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I5ZR78	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6ASZ6	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6GJE8	ENTREZGENE, UniProtKB/TrEMBL
	A6J135	ENTREZGENE, UniProtKB/TrEMBL
	A6J137	ENTREZGENE, UniProtKB/TrEMBL
	D3ZUL8	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-02-17	Zcchc8	zinc finger CCHC-type containing 8	Zcchc8	zinc finger, CCHC domain containing 8	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	Zcchc8	zinc finger, CCHC domain containing 8	Zcchc8_predicted	zinc finger, CCHC domain containing 8 (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Zcchc8_predicted	zinc finger, CCHC domain containing 8 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable

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