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Gene: Eif2ak1 (eukaryotic translation initiation factor 2 alpha kinase 1) Rattus norvegicus
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Symbol: Eif2ak1
Name: eukaryotic translation initiation factor 2 alpha kinase 1
Description: Exhibits eukaryotic translation initiation factor 2alpha kinase activity. Predicted to be involved in several processes, including macrophage differentiation; regulation of cellular macromolecule biosynthetic process; and response to iron ion starvation. Predicted to localize to the cytoplasm. Orthologous to human EIF2AK1 (eukaryotic translation initiation factor 2 alpha kinase 1); PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; hepatitis C pathway; influenza A pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; ammonium chloride; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: eukaryotic translation initiation factor 2-alpha kinase 1; HCR; heme-controlled repressor; heme-regulated eukaryotic initiation factor eIF-2-alpha kinase; heme-regulated inhibitor; hemin-sensitive initiation factor 2-alpha kinase; hemin-sensitive initiation factor 2a kinase; Hri
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01212,749,026 - 12,782,078 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1212,748,785 - 12,782,146 (-)Ensembl
Rnor_5.01214,792,379 - 14,825,284 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41211,039,139 - 11,072,708 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11210,969,549 - 11,102,636 (-)NCBI
Celera1212,508,244 - 12,541,227 (-)NCBICelera
Cytogenetic Map12p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Eif2ak1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 70883
Created: 2002-07-09
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.