Gene: Alox5ap (arachidonate 5-lipoxygenase activating protein) Rattus norvegicus
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Symbol: Alox5ap
Name: arachidonate 5-lipoxygenase activating protein
Description: ENCODES a protein that exhibits arachidonate 5-lipoxygenase activity; enzyme binding; protein heterodimerization activity; INVOLVED IN leukotriene biosynthetic process; lipoxygenase pathway; positive regulation of acute inflammatory response; PARTICIPATES IN leukotriene metabolic pathway; lipoxygenase mediated pathway of arachidonic acid metabolism; ASSOCIATED WITH glomerulonephritis; Hyperoxia; Inflammation; FOUND IN cytosol; endoplasmic reticulum; nuclear envelope; INTERACTS WITH 17alpha-ethynylestradiol; 3-[3-(tert-butylsulfanyl)-1-(4-chlorobenzyl)-5-(propan-2-yl)-1H-indol-2-yl]-2,2-dimethylpropanoic acid; ammonium chloride
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 5-lipoxygenase-activating protein FLAP; 5-lipoxygenase-activating protein, FLAP; arachidonate 5-lipoxygenase-activating protein; FLAP; MK-886-binding protein
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0126,854,930 - 6,879,112 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0128,950,727 - 8,974,708 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4126,245,808 - 6,269,796 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1126,245,808 - 6,269,796 (-)NCBI
Celera127,507,392 - 7,531,448 (-)NCBICelera
Cytogenetic Map12p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Alox5ap
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2097
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-01-30
Status: ACTIVE