Ralbp1l1 (ralA binding protein 1 like 1) - Rat Genome Database

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Gene: Ralbp1l1 (ralA binding protein 1 like 1) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Ralbp1l1 (Ensembl: LOC304239)
Name: ralA binding protein 1 like 1 (Ensembl:similar to RalA binding protein 1)
RGD ID: 1565198
Description: Predicted to enable GTPase activator activity and small GTPase binding activity. Predicted to be involved in small GTPase-mediated signal transduction. Human ortholog(s) of this gene implicated in pancreatic adenocarcinoma. Orthologous to human RALBP1 (ralA binding protein 1).
Type: protein-coding
RefSeq Status: MODEL
Previously known as: AABR07011057.1; LOC304239; ralA-binding protein 1; rho GTPase-activating protein 20; similar to RalA binding protein 1; uncharacterized protein Ralbp1l1
RGD Orthologs
Alliance Genes
More Info homologs ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8129,237,829 - 9,280,358 (-)NCBIGRCr8
mRatBN7.2124,201,357 - 4,246,044 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl124,201,359 - 4,238,722 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.02157,031,044 - 157,071,062 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2157,031,018 - 157,066,781 (-)NCBIRnor6.0rn6Rnor6.0
Rnor_5.02176,396,080 - 176,400,565 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4124,545,592 - 4,606,802 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Cytogenetic Map12p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
membrane  (IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

Genomics

Variants

.
Variants in Ralbp1l1
141 total Variants

QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300174Bw15Body weight QTL 152.93body mass (VT:0001259)body weight loss (CMO:0001399)1219318387Rat
2312418Kidm41Kidney mass QTL 413.70.0001kidney mass (VT:0002707)single kidney wet weight to body weight ratio (CMO:0000622)12119611090Rat
10755457Coatc14Coat color QTL 140.01759coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)12122591684Rat
6893681Bw109Body weight QTL 1092.30.004body mass (VT:0001259)body weight (CMO:0000012)12123297788Rat
1581516Cm56Cardiac mass QTL 564.20.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)12129333307Rat
1598855Bp294Blood pressure QTL 2943.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)12134851688Rat
7411660Foco28Food consumption QTL 2810.90.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12142110980Rat
9590086Insglur6Insulin/glucose ratio QTL 618.970.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)12142110980Rat
8694179Bw150Body weight QTL 1502.90.001body mass (VT:0001259)body weight gain (CMO:0000420)12142110980Rat
7411586Foco5Food consumption QTL 55.40.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12142110980Rat
7411595Foco9Food consumption QTL 940.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12142110980Rat
7411545Bw128Body weight QTL 1285.20.001body mass (VT:0001259)body weight gain (CMO:0000420)12142110980Rat
9590147Scort7Serum corticosterone level QTL 713.610.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)12142110980Rat
2303575Insul14Insulin level QTL 144blood insulin amount (VT:0001560)blood insulin level (CMO:0000349)12142450532Rat
737979Pia22Pristane induced arthritis QTL 2253.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)12144465750Rat
634351Apr5Acute phase response QTL 56.7blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)12144503507Rat
2302042Pia38Pristane induced arthritis QTL 383.50.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)12144503507Rat
7243862Mcs30Mammary carcinoma susceptibility QTL 308.62mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)127977298525593Rat
634350Apr4Acute phase response QTL 46orosomucoid 1 amount (VT:0010541)plasma orosomucoid 1 level (CMO:0001467)12117200546172005Rat
724526Uae3Urinary albumin excretion QTL 34.90.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)12390696910373166Rat


Expression


Sequence


RefSeq Acc Id: ENSRNOT00000076491   ⟹   ENSRNOP00000068321
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl124,201,359 - 4,238,722 (-)Ensembl
RefSeq Acc Id: XM_056984758   ⟹   XP_056840738
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8129,237,829 - 9,280,358 (-)NCBI
mRatBN7.2124,201,357 - 4,246,027 (-)NCBI
Protein Sequences
Protein RefSeqs XP_056840738 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH97303 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000068321.2
RefSeq Acc Id: ENSRNOP00000068321   ⟸   ENSRNOT00000076491
RefSeq Acc Id: XP_056840738   ⟸   XM_056984758
Protein Domains
Rho-GAP

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F1LR97-F1-model_v2 AlphaFold F1LR97 1-776 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1565198 AgrOrtholog
BioCyc Gene G2FUF-20260 BioCyc
Ensembl Genes ENSRNOG00000000889 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000076491.3 UniProtKB/TrEMBL
Gene3D-CATH 1.10.555.10 UniProtKB/TrEMBL
  1.20.58.90 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7115612 IMAGE-MGC_LOAD
  IMAGE:7453689 IMAGE-MGC_LOAD
InterPro RALBP1 UniProtKB/TrEMBL
  RalBP1-like_Ral-bd UniProtKB/TrEMBL
  Rho_GTPase_activation_prot UniProtKB/TrEMBL
  RhoGAP_dom UniProtKB/TrEMBL
MGC_CLONE MGC:114296 IMAGE-MGC_LOAD
  MGC:188057 IMAGE-MGC_LOAD
NCBI Gene 304239 ENTREZGENE
PANTHER PTHR12783 UniProtKB/TrEMBL
  RALA-BINDING PROTEIN 1 UniProtKB/TrEMBL
Pfam RhoGAP UniProtKB/TrEMBL
  RLIP76_Ral-bd UniProtKB/TrEMBL
PhenoGen Ralbp1l1 PhenoGen
PROSITE RHOGAP UniProtKB/TrEMBL
RatGTEx ENSRNOG00000000889 RatGTEx
SMART RhoGAP UniProtKB/TrEMBL
Superfamily-SCOP SSF48350 UniProtKB/TrEMBL
UniProt A0A096MJZ5_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-09-19 Ralbp1l1  ralA binding protein 1 like 1  LOC304239  similar to RalA binding protein 1  Symbol and Name Changed 1299863 APPROVED
2022-06-02 LOC304239  similar to RalA binding protein 1  AABR07011057.1    Data merged from RGD:15003217 737654 PROVISIONAL
2019-11-08 AABR07011057.1        Symbol and Name status set to provisional 45752 PROVISIONAL
2006-02-09 LOC304239  similar to RalA binding protein 1      Symbol and Name status set to provisional 70820 PROVISIONAL