Gusb (glucuronidase, beta) - Rat Genome Database

Name: Gusb
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

	Submit Data \| Help \| Video Tutorials \| News \| Publications \| Download \| REST API \| Citing RGD \| Contact
	Search RGD Grant Resources Citing RGD About Us Contact Us Genes QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data OntoMate (Literature Search) JBrowse (Genome Browser) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) RatMine GViewer (Genome Viewer) Overgo Probe Designer ACP Haplotyper Genome Scanner VCMap Aging & Age-Related Disease Cancer Cardiovascular Disease COVID-19 Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease Find Models new Genetic Models Autism Models PhenoMiner (Quantitative Phenotypes) Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes GERRC (Gene Editing Rat Resource Center) Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive Pathways Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Poster Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
	Advanced Search (OLGA)

Gene: Gusb (glucuronidase, beta) Rattus norvegicus

Analyze

Symbol:

Gusb

Name:

glucuronidase, beta

RGD ID:

2772

Description:

Exhibits beta-glucuronidase activity and carbohydrate binding activity. Predicted to be involved in glucuronoside catabolic process. Localizes to lysosome. Human ortholog(s) of this gene implicated in Sly syndrome. Orthologous to human GUSB (glucuronidase beta); PARTICIPATES IN acute intermittent porphyria pathway; congenital sucrase-isomaltase deficiency pathway; erythropoietic porphyria pathway; INTERACTS WITH (+)-schisandrin B; (-)-epigallocatechin 3-gallate; (R)-lipoic acid.

Type:

protein-coding

RefSeq Status:

VALIDATED

Also known as:

Ac2-223; beta-glucuronidase; Gus-s

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	GUSB (glucuronidase beta)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Gusb (glucuronidase, beta)	HGNC	Treefam, EggNOG, OrthoMCL, NCBI, OMA, HomoloGene, Inparanoid, Panther, OrthoDB, Ensembl
Chinchilla lanigera (long-tailed chinchilla):	Gusb (glucuronidase beta)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	GUSB (glucuronidase beta)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	GUSB (glucuronidase beta)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Gusb (glucuronidase beta)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	GUSB (glucuronidase beta)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (African green monkey):	LOC103246571 (beta-glucuronidase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Gusb (glucuronidase beta)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	GUSBP11 (GUSB pseudogene 11)	HGNC	PhylomeDB
Alliance orthologs ³
Homo sapiens (human):	GUSB (glucuronidase beta)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER)
Mus musculus (house mouse):	Gusb (glucuronidase, beta)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER)
Danio rerio (zebrafish):	gusb (glucuronidase, beta)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER)
Drosophila melanogaster (fruit fly):	CG15117	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoInspector\|PANTHER)
Caenorhabditis elegans (roundworm):	Y105E8B.9	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER)
Drosophila melanogaster (fruit fly):	betaGlu	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoInspector\|PANTHER)

Latest Assembly:

Rnor_6.0 - RGSC Genome Assembly v6.0

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	12	26,701,191 - 26,714,718 (+)	NCBI
Rnor_6.0 Ensembl	12	30,198,822 - 30,227,771 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0	12	30,202,066 - 30,215,583 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	12	32,139,367 - 32,152,883 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	12	27,744,409 - 27,757,755 (+)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	12	27,607,658 - 27,620,971 (+)	NCBI
Celera	12	28,414,852 - 28,428,552 (+)	NCBI		Celera
Cytogenetic Map	12	q12	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

argininosuccinic aciduria (ISO)

Experimental Arthritis (IEP)

Hydrops Fetalis (ISO)

intellectual disability (ISO)

mucopolysaccharidosis (IEP)

mucopolysaccharidosis VI (ISO)

nervous system disease (ISO)

Otitis Media with Effusion (ISO)

peritonitis (IEP)

pleomorphic xanthoastrocytoma (ISO)

prostate cancer (ISO)

proteinuria (ISO)

Sly syndrome (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-alpha-tocopherol (ISO)

(+)-schisandrin B (EXP)

(-)-epigallocatechin 3-gallate (EXP,ISO)

(R)-lipoic acid (EXP)

1,1-dichloroethene (ISO)

1,2-dimethylhydrazine (ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2,4-dinitrotoluene (EXP)

2,6-dinitrotoluene (EXP)

2-acetyl-1-alkyl-sn-glycero-3-phosphocholine (EXP)

3-isobutyl-1-methyl-7H-xanthine (ISO)

4,4'-diaminodiphenylmethane (ISO)

4-\{[(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)carbonyl]amino\}benzoic acid (ISO)

4-hydroxyphenyl retinamide (ISO)

5-aza-2'-deoxycytidine (ISO)

acrolein (ISO)

acrylamide (EXP,ISO)

aflatoxin B1 (ISO)

alpha-pinene (ISO)

amlodipine (EXP)

ammonium chloride (EXP)

anthocyanin (EXP)

atrazine (EXP)

benoxaprofen (ISO)

benzene (EXP)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

carbamazepine (ISO)

carbon nanotube (ISO)

choline (ISO)

cis-caffeic acid (EXP)

cobalt dichloride (EXP)

compound 48/80 (EXP)

cumene hydroperoxide (ISO)

curcumin (EXP)

cyclophosphamide (EXP)

cytochalasin B (EXP)

D-mannopyranose 6-phosphate (ISO)

D-mannose 6-phosphate (ISO)

dexamethasone (ISO)

dibutyl phthalate (EXP)

diethylstilbestrol (ISO)

divanadium pentaoxide (ISO)

doxorubicin (ISO)

ellagic acid (EXP)

endosulfan (EXP)

ethanol (EXP,ISO)

ethyl methanesulfonate (ISO)

fenvalerate (ISO)

ferulic acid (EXP)

Fexofenadine hydrochloride (ISO)

flavonoids (EXP)

flurbiprofen (ISO)

flutamide (EXP)

folic acid (ISO)

gamma-hexachlorocyclohexane (EXP)

genistein (EXP,ISO)

gentamycin (EXP)

glafenine (EXP)

glycine betaine (EXP)

histamine (ISO)

indometacin (ISO)

isoprenaline (EXP)

L-ascorbic acid (EXP)

L-methionine (ISO)

lipoic acid (EXP)

lipopolysaccharide (EXP,ISO)

mangiferin (EXP)

menadione (ISO)

methoxychlor (EXP)

methyl methanesulfonate (ISO)

myrtenal (EXP)

N,O-dimethyltyramine (EXP)

N-formyl-L-methionyl-L-leucyl-L-phenylalanine (EXP,ISO)

N-nitrosodiethylamine (EXP)

naringin (EXP)

nefazodone (EXP)

nickel dichloride (EXP)

nicorandil (EXP)

ozone (ISO)

paclitaxel (ISO)

paracetamol (ISO)

parathion-methyl (EXP)

phenobarbital (EXP)

phenytoin (ISO)

pirinixic acid (EXP)

potassium chromate (ISO)

resveratrol (ISO)

S-allylcysteine (EXP)

selenic acid (EXP)

silver atom (ISO)

silver(0) (ISO)

Soman (EXP)

sunitinib (ISO)

suramin (EXP)

tert-butyl hydroperoxide (ISO)

tetrachloromethane (EXP,ISO)

titanium dioxide (ISO)

trans-caffeic acid (EXP)

Triptolide (ISO)

valproic acid (ISO)

vancomycin (ISO)

vincaleukoblastine (ISO)

vinclozolin (EXP)

vitamin E (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

carbohydrate metabolic process (IEA,ISO)

glucuronoside catabolic process (IBA,ISO)

Cellular Component

extracellular space (IBA,IEA,ISO)

intracellular membrane-bounded organelle (ISO)

lysosome (IDA,IEA,ISO)

Molecular Function

beta-glucuronidase activity (IBA,IDA,IEA,IMP,ISO)

carbohydrate binding (IBA,IDA)

hydrolase activity (ISO)

protein domain specific binding (IEA,ISO)

signaling receptor binding (IBA,IEA,ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

acute intermittent porphyria pathway (ISO)

congenital sucrase-isomaltase deficiency pathway (ISO)

erythropoietic porphyria pathway (ISO)

glycogen storage disease type III pathway (ISO)

glycogen storage disease type IV pathway (ISO)

glycogen storage disease type VI pathway (ISO)

glycosaminoglycan degradation pathway (IEA)

hereditary coproporphyria pathway (ISO)

pentose and glucuronate interconversion pathway (IEA)

porphyrin and chlorophyll metabolic pathway (IEA)

porphyrin metabolic pathway (ISO)

starch and sucrose metabolic pathway (IEA,ISO)

variegate porphyria pathway (ISO)

References

References - curated


1.	Arrigoni-Martelli E, Fed Proc. 1976 Nov;35(13):2457-7.
2.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	GOA data from the GO Consortium
4.	KEGG
5.	MGD data from the GO Consortium
6.	NCBI rat LocusLink and RefSeq merged data July 26, 2002
7.	Nishimura Y, etal., Proc Natl Acad Sci U S A 1986 Oct;83(19):7292-6.
8.	Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
9.	OMIM Disease Annotation Pipeline
10.	Online Mendelian Inheritance in Man, OMIM (TM).
11.	Oshima A, etal., Proc Natl Acad Sci U S A 1987 Feb;84(3):685-9.
12.	Pipeline to import KEGG annotations from KEGG into RGD
13.	Pipeline to import SMPDB annotations from SMPDB into RGD
14.	Powell PP, etal., Biochem J 1988 Mar 1;250(2):547-55.
15.	Rajashree S and Puvanakrishnan R, Mol Cell Biochem. 1996 Jan 26;154(2):165-70.
16.	Rees S, etal., Virchows Arch B Cell Pathol Incl Mol Pathol. 1986;52(3):259-72. doi: 10.1007/BF02889967.
17.	RGD automated data pipeline
18.	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
19.	RGD automated import pipeline for gene-chemical interactions
20.	Sleat DE, etal., J Biol Chem. 1996 Aug 9;271(32):19191-8.
21.	Sofia DR, etal., Agents Actions. 1976 Nov;6(6):728-34. doi: 10.1007/BF02026096.
22.	Wolfe JH, etal., Nature 1992 Dec 24-31;360(6406):749-53.

Additional References at PubMed

PMID:1914521	PMID:4777306	PMID:4841576	PMID:7203014	PMID:8889548	PMID:12782150	PMID:15358052	PMID:18523484	PMID:19056867	PMID:19710420	PMID:19751987	PMID:19946888
PMID:20028034	PMID:23376485	PMID:23533145	PMID:25645918	PMID:29078076	PMID:29514215

Genomics

Comparative Map Data

Gusb
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	12	26,701,191 - 26,714,718 (+)	NCBI
Rnor_6.0 Ensembl	12	30,198,822 - 30,227,771 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0	12	30,202,066 - 30,215,583 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	12	32,139,367 - 32,152,883 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	12	27,744,409 - 27,757,755 (+)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	12	27,607,658 - 27,620,971 (+)	NCBI
Celera	12	28,414,852 - 28,428,552 (+)	NCBI		Celera
Cytogenetic Map	12	q12	NCBI

GUSB
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38.p13 Ensembl	7	65,960,684 - 65,982,215 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh38	7	65,960,684 - 65,982,230 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh37	7	65,425,671 - 65,447,200 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	7	65,063,106 - 65,084,681 (-)	NCBI	NCBI36		hg18	NCBI36
Build 34	7	64,869,824 - 64,891,346	NCBI
Celera	7	66,666,375 - 66,688,005 (+)	NCBI
Cytogenetic Map	7	q11.21	NCBI
HuRef	7	61,613,080 - 61,634,635 (-)	NCBI		HuRef
CHM1_1	7	65,520,933 - 65,542,533 (-)	NCBI		CHM1_1
CRA_TCAGchr7v2	7	64,763,190 - 64,784,820 (-)	NCBI

Gusb
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	5	130,011,278 - 130,031,890 (-)	NCBI	GRCm39		mm39
GRCm39 Ensembl	5	130,017,852 - 130,031,890 (-)	Ensembl
GRCm38	5	129,989,011 - 130,003,049 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	5	129,989,011 - 130,003,049 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	5	130,464,891 - 130,478,698 (-)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	5	130,273,724 - 130,287,531 (-)	NCBI			mm8
Celera	5	126,991,862 - 127,006,971 (-)	NCBI		Celera
Cytogenetic Map	5	G1.3	NCBI
cM Map	5	68.32	NCBI

Gusb
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955456	8,378,654 - 8,392,252 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955456	8,377,161 - 8,392,298 (-)	NCBI	ChiLan1.0	ChiLan1.0

GUSB
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	7	64,724,628 - 64,745,040 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	7	64,724,841 - 64,744,909 (-)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	7	60,087,130 - 60,109,289 (+)	NCBI	Mhudiblu_PPA_v0		panPan3

GUSB
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	6	730,345 - 743,916 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	6	730,358 - 779,424 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	6	2,430,980 - 2,444,321 (-)	NCBI
ROS_Cfam_1.0	6	535,764 - 548,724 (-)	NCBI
UMICH_Zoey_3.1	6	479,152 - 492,513 (-)	NCBI
UNSW_CanFamBas_1.0	6	473,517 - 486,454 (-)	NCBI
UU_Cfam_GSD_1.0	6	644,508 - 657,770 (-)	NCBI

Gusb
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409344	126,304,099 - 126,314,709 (-)	NCBI
SpeTri2.0	NW_004936543	7,721,273 - 7,732,468 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

GUSB
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	3	16,671,420 - 16,689,231 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	3	16,672,071 - 16,686,520 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	3	16,924,697 - 16,939,444 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

LOC103246571
(Chlorocebus sabaeus - African green monkey)

Vervet Assembly	Chr	Position (strand)	Source	Genome Browsers
Vervet Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	28	1,621,293 - 1,646,097 (-)	NCBI

Gusb
(Heterocephalus glaber - naked mole-rat)

Molerat Assembly	Chr	Position (strand)	Source	Genome Browsers
Molerat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624740	8,390,096 - 8,401,063 (-)	NCBI

Position Markers

D5Mit27

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	12	26,704,113 - 26,704,326 (+)	MAPPER
Rnor_6.0	12	30,204,978 - 30,205,190	NCBI	Rnor6.0
Rnor_5.0	12	32,142,279 - 32,142,491	UniSTS	Rnor5.0
RGSC_v3.4	12	27,747,321 - 27,747,533	UniSTS	RGSC3.4
Celera	12	28,417,763 - 28,417,975	UniSTS
Cytogenetic Map	12	q13	UniSTS

Gus-s

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	12	26,704,111 - 26,704,346 (+)	MAPPER
Rnor_6.0	12	30,204,976 - 30,205,210	NCBI	Rnor6.0
Rnor_5.0	12	32,142,277 - 32,142,511	UniSTS	Rnor5.0
RGSC_v3.4	12	27,747,319 - 27,747,553	UniSTS	RGSC3.4
Celera	12	28,417,761 - 28,417,995	UniSTS
Cytogenetic Map	12	q13	UniSTS

RH130072

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	12	26,714,495 - 26,714,645 (+)	MAPPER
Rnor_6.0	12	30,215,363 - 30,215,512	NCBI	Rnor6.0
Rnor_5.0	12	32,152,663 - 32,152,812	UniSTS	Rnor5.0
RGSC_v3.4	12	27,757,535 - 27,757,684	UniSTS	RGSC3.4
Celera	12	28,428,332 - 28,428,481	UniSTS
RH 3.4 Map	12	452.5	UniSTS
Cytogenetic Map	12	q13	UniSTS

QTLs in Region (Rnor_6.0)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1581516	Cm56	Cardiac mass QTL 56	4.2	0.05	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	12	1	30749723	Rat
1598855	Bp294	Blood pressure QTL 294	3.5		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	12	1	36919844	Rat
7387292	Kidm42	Kidney mass QTL 42	3.03	0.0004	kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	12	1	38334225	Rat
9590086	Insglur6	Insulin/glucose ratio QTL 6	18.97	0.001	blood insulin amount (VT:0001560)	calculated plasma insulin level (CMO:0002170)	12	150810	45150810	Rat
9590147	Scort7	Serum corticosterone level QTL 7	13.61	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	12	150810	45150810	Rat
7411545	Bw128	Body weight QTL 128	5.2	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	12	150810	45150810	Rat
7411586	Foco5	Food consumption QTL 5	5.4	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	150810	45150810	Rat
7411660	Foco28	Food consumption QTL 28	10.9	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	150810	45150810	Rat
7411595	Foco9	Food consumption QTL 9	4	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	150810	45150810	Rat
8694179	Bw150	Body weight QTL 150	2.9	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	12	150810	45150810	Rat
2303575	Insul14	Insulin level QTL 14	4		blood insulin amount (VT:0001560)	blood insulin level (CMO:0000349)	12	492578	45492578	Rat
737979	Pia22	Pristane induced arthritis QTL 22	53.1		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	12	2475687	47475687	Rat
634351	Apr5	Acute phase response QTL 5	6.7		blood interleukin-6 amount (VT:0008595)	plasma interleukin-6 level (CMO:0001927)	12	2513442	47513442	Rat
2302042	Pia38	Pristane induced arthritis QTL 38	3.5	0.001	blood immunoglobulin amount (VT:0002460)	serum immunoglobulin G1 level (CMO:0002115)	12	2513442	47513442	Rat
634350	Apr4	Acute phase response QTL 4	6		orosomucoid 1 amount (VT:0010541)	plasma orosomucoid 1 level (CMO:0001467)	12	4210051	49210051	Rat
7411547	Bw129	Body weight QTL 129		0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	6	9223626	52716770	Rat
7411588	Foco6	Food consumption QTL 6		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	9223626	52716770	Rat
7411597	Foco10	Food consumption QTL 10		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	9223626	52716770	Rat
7411641	Foco19	Food consumption QTL 19	27.7	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	9223626	52716770	Rat
8552918	Pigfal7	Plasma insulin-like growth factor 1 level QTL 7			blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	12	9223626	52716770	Rat
8552964	Pigfal17	Plasma insulin-like growth factor 1 level QTL 17	3.5		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	12	9223626	52716770	Rat
8552912	Pigfal6	Plasma insulin-like growth factor 1 level QTL 6	5		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	12	9223630	52716770	Rat
10059594	Kidm46	Kidney mass QTL 46	3.79	0.025	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	12	9789834	52716770	Rat
2293086	Iddm30	Insulin dependent diabetes mellitus QTL 30	3.82		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	12	10175889	31975590	Rat
61331	Eau2	Experimental allergic uveoretinitis QTL 2		0.0005	uvea integrity trait (VT:0010551)	experimental autoimmune uveitis score (CMO:0001504)	12	10256890	31723732	Rat
1300157	Rf21	Renal function QTL 21	4.4		renal blood flow trait (VT:2000006)	absolute change in renal blood flow rate (CMO:0001168)	12	11764995	37522089	Rat
1331755	Bp219	Blood pressure QTL 219	3.041		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	12	13127211	31723688	Rat
1331761	Bp218	Blood pressure QTL 218	2.973		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	12	13127211	50320041	Rat
61404	Bw120	Body weight QTL 120	5.1		body mass (VT:0001259)	body mass index (BMI) (CMO:0000105)	12	14419775	52716770	Rat
1549829	Scl48	Serum cholesterol level QTL 48	5		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	12	15021986	52716770	Rat
61416	Pia4	Pristane induced arthritis QTL 4	8.4		joint integrity trait (VT:0010548)	arthritic paw count (CMO:0001460)	12	15714609	35964508	Rat
61421	Cia12	Collagen induced arthritis QTL 12	4.6		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	12	15714609	41291738	Rat
2300186	Bmd59	Bone mineral density QTL 59	7.1	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	12	15908900	52716770	Rat
2293699	Bss49	Bone structure and strength QTL 49	5.61	0.0001	lumbar vertebra size trait (VT:0010518)	lumbar vertebra trabecular cross-sectional area (CMO:0001692)	12	15908900	52716770	Rat
631543	Bp83	Blood pressure QTL 83	5.8		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	12	17185580	44098244	Rat
2293684	Bmd26	Bone mineral density QTL 26	4.4	0.0002	femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	12	17960865	38409001	Rat
1641928	Alcrsp5	Alcohol response QTL 5			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	12	18342477	52716770	Rat
2303569	Gluco44	Glucose level QTL 44	2		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	12	18342477	52716770	Rat
2302060	Pia37	Pristane induced arthritis QTL 37	6.1	0.001	blood immunoglobulin amount (VT:0002460)	serum immunoglobulin G1 level (CMO:0002115)	12	18729043	52716770	Rat
1549902	Bp269	Blood pressure QTL 269			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	12	18752593	52716770	Rat
1549912	Bp268	Blood pressure QTL 268			arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	10	18752593	52716770	Rat
737822	Alc10	Alcohol consumption QTL 10	2.2		consumption behavior trait (VT:0002069)	ethanol drink intake rate (CMO:0001407)	12	22650702	45946937	Rat
5684888	Pia42	Pristane induced arthritis QTL 42			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	12	22650702	48598906	Rat
61324	Eae5	Experimental allergic encephalomyelitis QTL 5	14		nervous system integrity trait (VT:0010566)	percentage of study population developing relapsing-remitting experimental autoimmune encephalomyelitis during a period of time (CMO:0001402)	12	22650702	52716770	Rat
1298081	Cia25	Collagen induced arthritis QTL 25	4.7		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	12	22650721	41291738	Rat
70213	Niddm27	Non-insulin dependent diabetes mellitus QTL 27	3.72		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	12	22876297	43799153	Rat
631560	Apr1	Acute phase response QTL 1	6.1		orosomucoid 1 amount (VT:0010541)	plasma orosomucoid 1 level (CMO:0001467)	12	24906590	52716770	Rat
7411643	Foco20	Food consumption QTL 20		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	26098845	52716770	Rat
70169	Eae13	Experimental allergic encephalomyelitis QTL 13		0.032	nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)	12	27190240	42196641	Rat
1331763	Wbc2	White blood cell count QTL 2	3.162		leukocyte quantity (VT:0000217)	total white blood cell count (CMO:0000365)	12	27285473	36161779	Rat
8693658	Alc33	Alcohol consumption QTL 33	2.1	0.68	drinking behavior trait (VT:0001422)	calculated ethanol drink intake rate (CMO:0001615)	12	29113609	49560679	Rat
8693635	Alc28	Alcohol consumption QTL 28	2.7	0.439	drinking behavior trait (VT:0001422)	calculated ethanol drink intake rate (CMO:0001615)	12	29113609	50757185	Rat

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	230
Count of miRNA genes:	159
Interacting mature miRNAs:	179
Transcripts:	ENSRNOT00000001215, ENSRNOT00000041645
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	2	28	51	41	19	41			28	28	34	11
Low	1	15	6				8	11	46	7	7		8
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_017015	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017598254	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017598255	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039089057	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC113710	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY321342	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CB792679	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473973	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CV795146	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000227	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	M13962	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	Y00717	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000001215 ⟹ ENSRNOP00000001215

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	12	30,202,055 - 30,215,581 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000041645 ⟹ ENSRNOP00000045033

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	12	30,198,822 - 30,227,771 (+)	Ensembl

RefSeq Acc Id:

NM_017015 ⟹ NP_058711

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	12	26,701,200 - 26,714,716 (+)	NCBI
Rnor_6.0	12	30,202,066 - 30,215,583 (+)	NCBI
Rnor_5.0	12	32,139,367 - 32,152,883 (+)	NCBI
RGSC_v3.4	12	27,744,409 - 27,757,755 (+)	RGD
Celera	12	28,414,852 - 28,428,552 (+)	RGD

Sequence:

show sequence

AGGCCCAGCCGCTGGACGGCGGGCATCCCGGCCAGCATGTCCCCAAGACGGAGTGTGTGTTGGT
TCGTACTGGGCCAGCTGCTGTGCAGCTGCGCGCTGGCGCTGCAGGGCGGGATGCTGTTCCCGAA
GGAGACCCCTTCGCGGGAACTCAAGGTGCTGGACGGCCTGTGGAGCTTCCGTGCCGATTACTCG
AACAATCGGTTGCAGGGCTTCGAGAAGCAGTGGTACCGGCAGCCGCTACGGGAGTCGGGCCCAA
CCTTGGACATGCCGGTCCCTTCCAGCTTCAATGACATCACCCAAGAAGCAGAGCTTCGGAACTT
CATTGGCTGGGTGTGGTATGAACGGGAAGCAGTGCTTCCACAGCGATGGACCCAGGACACCGAC
AGGAGAGTGGTGTTGAGAATCAACAGCGCCCATTACTATGCAGTTGTGTGGGTGAATGGGATTC
ATGTGGTGGAACATGAGGGAGGTCACCTCCCCTTTGAGGCTGACATCACCAAGCTGGTCCAGAG
TGGGCCCCTGACCACCTTCCGGGTCACCATCGCCATCAACAACACACTGACCCCTTATACCCTT
CCACCGGGGACCATTGTCTACAAGACTGATCCTTCCATGTATCCCAAGGGTTACTTCGTCCAGG
ACATAAGCTTCGACTTCTTCAACTATGCGGGGCTGCACCGGTCTGTGGTCCTGTACACCACCCC
TACCACCTATATCGATGATATCACTGTGACCACTGACGTGGACCGGGACGTTGGGCTGGTGAAC
TACTGGATTTCTGTCCAGGGCAGTGACCATTTCCAGCTAGAAGTGCGTCTTCTGGATGAGGATG
GCAAAATTGTGGCCCGTGGAACAGGGAATGAGGGTCAACTTAAGGTGCCGCGTGCCCACCTCTG
GTGGCCTTACCTGATGCATGAGCATCCAGCCTACCTGTACTCCTTGGAGGTGACGATGACAACA
CCTGAGTCTGTGTCTGACTTCTATACCCTCCCTGTCGGGATTCGAACAGTGGCTGTCACAAAGA
GCAAGTTCCTCATAAATGGGAAGCCTTTCTACTTCCAAGGCGTCAACAAGCATGAGGATTCAGA
TATCCGAGGGAGAGGCTTCGACTGGCCTCTGCTGATAAAGGATTTCAACCTCCTCCGTTGGCTC
GGGGCAAATTCCTTTCGTACCAGCCACTATCCCTACTCGGAGGAGGTACTTCAGCTCTGTGACC
GATATGGAATTGTGGTCATCGATGAGTGTCCCGGTGTGGGCATCGTGCTGCCCCAGAGTTTTGG
CAACGTGTCTCTTCGGCACCACCTAGAGGTGATGGACGAGCTGGTGCGCAGGGACAAAAATCAC
CCTGCGGTCGTGATGTGGTCTGTGGCCAATGAGCCTGTCTCTTCTCTGAAACCTGCCGGATATT
ACTTCAAGACGCTGATCGCCCACACCAAAGCCCTGGACCCCACCCGTCCTGTGACCTTTGTGAG
CAATACCAGATATGACGCAGACATGGGGGCCCCGTACGTGGACGTGATTTGTGTGAACAGTTAC
TTATCCTGGTATCATGACTACGGGCATCTGGAGGTGATTCAGCTGCAGCTGACTAGCCAGTTTG
AGAACTGGTATAAGATGTACCAGAAGCCAATTATCCAGAGCGAGTATGGAGCAGACGCCGTCTC
GGGGCTTCATGAGGATCCACCTCGCATGTTCAGTGAGGAGTACCAGACAGCTCTCCTGGAGAAT
TATCATTTGATCCTGGATGAGAAACGAAAAGAATATGTCATCGGAGAGCTCATCTGGAATTTTG
CTGACTTCATGACGAACCAGTCACCACTGAGAGTAACAGGAAACAAGAAGGGGATCTTCACTCG
ACAGAGAAACCCCAAGATGGCAGCCTTCATTTTGCGAGAGAGATACTGGAGGATTGCCAACGAA
ACCAGAGGTTACGGTTCAGTGCCGAGGACCCAGTGTATGGGAAGCAGACCGTTCACATTCTAAA
GCTACGACTACCTCACCGCAGACAGGGCCTGATGAAGTGAAAGGTATTCTCTCAGCAGAAGAGT
TTTTCCTCTGGAGTTTGTGAACCAACACAAGGGGGACTTTAGAAGTGACATGGAAGTTTTCCTT
GTGTGGGGATAATGACTTGCAGTGCCTTAGGCTCAGTAATGTGTCCTGCTGAGAAGTGTCCCAG
GTCATTTCTGTCAGGTTTTTTTTGGCCTTGGCTTTGTGTACTCTTGAAAACCTACTGTGTGAAT
ACTCACACTAAGAGCTCCTGGTTACCGGCTGAGGGACGGCTCACAATTTAAGAATACTGACTGT
TCTACCAGGGGTTCCAGATTCGATTCCTAGCACCCACGTGGTCGTTAACTATGAGCTGTTGCCC
CATTTCTCAGGTGATGTACGAACATACATGTGGGGGGAGGGGAATAGTCATACGTGTAAAATGA
AAATAAATCTAAATAAAACTGTTTTCTTTCATTATAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_017598254 ⟹ XP_017453743

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	12	30,204,265 - 30,215,583 (+)	NCBI

Sequence:

show sequence

TGAACGGGAAGCAGTGCTTCCACAGCGATGGACCCAGGACACCGACAGGAGAGTGGTGTTGAGA
ATCAACAGCGCCCATTACTATGCAGTTGTGGTATCCCAAGGGTTACTTCGTCCAGGACATAAGC
TTCGACTTCTTCAACTATGCGGGGCTGCACCGGTCTGTGGTCCTGTACACCACCCCTACCACCT
ATATCGATGATATCACTGTGACCACTGACGTGGACCGGGACGTTGGGCTGGTGAACTACTGGAT
TTCTGTCCAGGGCAGTGACCATTTCCAGCTAGAAGTGCGTCTTCTGGATGAGGATGGCAAAATT
GTGGCCCGTGGAACAGGGAATGAGGGTCAACTTAAGGTGCCGCGTGCCCACCTCTGGTGGCCTT
ACCTGATGCATGAGCATCCAGCCTACCTGTACTCCTTGGAGGTGACGATGACAACACCTGAGTC
TGTGTCTGACTTCTATACCCTCCCTGTCGGGATTCGAACAGTGGCTGTCACAAAGAGCAAGTTC
CTCATAAATGGGAAGCCTTTCTACTTCCAAGGCGTCAACAAGCATGAGGATTCAGATATCCGAG
GGAGAGGCTTCGACTGGCCTCTGCTGATAAAGGATTTCAACCTCCTCCGTTGGCTCGGGGCAAA
TTCCTTTCGTACCAGCCACTATCCCTACTCGGAGGAGGTACTTCAGCTCTGTGACCGATATGGA
ATTGTGGTCATCGATGAGTGTCCCGGTGTGGGCATCGTGCTGCCCCAGAGTTTTGGCAACGTGT
CTCTTCGGCACCACCTAGAGGTGATGGACGAGCTGGTGCGCAGGGACAAAAATCACCCTGCGGT
CGTGATGTGGTCTGTGGCCAATGAGCCTGTCTCTTCTCTGAAACCTGCCGGATATTACTTCAAG
ACGCTGATCGCCCACACCAAAGCCCTGGACCCCACCCGTCCTGTGACCTTTGTGAGCAATACCA
GATATGACGCAGACCTGGGGGCCCCGTACGTGGACGTGATTTGTGTGAACAGTTACTTATCCTG
GTATCATGACTACGGGCATCTGGAGGTGATTCAGCTGCAGCTGACTAGCCAGTTTGAGAACTGG
TATAAGATGTACCAGAAGCCAATTATCCAGAGCGAGTATGGAGCAGACGCCGTCTCGGGGCTTC
ATGAGGATCCACCTCGCATGTTCAGTGAGGAGTACCAGACAGCTCTCCTGGAGAATTATCATTT
GATCCTGGATGAGAAACGAAAAGAATATGTCATCGGAGAGCTCATCTGGAATTTTGCTGACTTC
ATGACGAACCAGTCACCACTGAGAGTAACAGGAAACAAGAAGGGGATCTTCACTCGACAGAGAA
ACCCCAAGATGGCAGCCTTCATTTTGCGAGAGAGATACTGGAGGATTGCCAACGAAACCAGAGG
TTACGGTTCAGTGCCGAGGACCCAGTGTATGGGAAGCAGACCGTTCACATTCTAAAGCTACGAC
TACCTCACCGCAGACAGGGCCTGATGAAGTGAAAGGTATTCTCTCAGCAGAAGAGTTTTTCCTC
TGGAGTTTGTGAACCAACACAAGGGGGACTTTAGAAGTGACATGGAAGTTTTCCTTGTGTGGGG
ATAATGACTTGCAGTGCCTTAGGCTCAGTAATGTGTCCTGCTGAGAAGTGTCCCAGGTCATTTC
TGTCAGGTTTTTTTTGGCCTTGGCTTTGTGTACTCTTGAAAACCTACTGTGTGAATACTCACAC
TAAGAGCTCCTGGTTACCGGCTGAGGGACGGCTCACAATTTAAGAATACTGACTGTTCTACCAG
GGGTTCCAGATTCGATTCCTAGCACCCACGTGGTCGTTAACTATGAGCTGTTGCCCCATTTCTC
AGGTGATGTACGAACATACATGTGGGGGGAGGGGAATAGTCATACGTGTAAAATGAAAATAAAT
CTAAATAAAACTGTTTTCTTTCATTAT

hide sequence

RefSeq Acc Id:

XM_017598255 ⟹ XP_017453744

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	12	26,703,428 - 26,714,718 (+)	NCBI
Rnor_6.0	12	30,204,292 - 30,215,583 (+)	NCBI

Sequence:

show sequence

ATGGACCCAGGACACCGACAGGAGAGTGGTGTTGAGAATCAACAGCGCCCATTACTATGCAGTT
GTGGGCTGGTGAACTACTGGATTTCTGTCCAGGGCAGTGACCATTTCCAGCTAGAAGTGCGTCT
TCTGGATGAGGATGGCAAAATTGTGGCCCGTGGAACAGGGAATGAGGGTCAACTTAAGGTGCCG
CGTGCCCACCTCTGGTGGCCTTACCTGATGCATGAGCATCCAGCCTACCTGTACTCCTTGGAGG
TGACGATGACAACACCTGAGTCTGTGTCTGACTTCTATACCCTCCCTGTCGGGATTCGAACAGT
GGCTGTCACAAAGAGCAAGTTCCTCATAAATGGGAAGCCTTTCTACTTCCAAGGCGTCAACAAG
CATGAGGATTCAGATATCCGAGGGAGAGGCTTCGACTGGCCTCTGCTGATAAAGGATTTCAACC
TCCTCCGTTGGCTCGGGGCAAATTCCTTTCGTACCAGCCACTATCCCTACTCGGAGGAGGTACT
TCAGCTCTGTGACCGATATGGAATTGTGGTCATCGATGAGTGTCCCGGTGTGGGCATCGTGCTG
CCCCAGAGTTTTGGCAACGTGTCTCTTCGGCACCACCTAGAGGTGATGGACGAGCTGGTGCGCA
GGGACAAAAATCACCCTGCGGTCGTGATGTGGTCTGTGGCCAATGAGCCTGTCTCTTCTCTGAA
ACCTGCCGGATATTACTTCAAGACGCTGATCGCCCACACCAAAGCCCTGGACCCCACCCGTCCT
GTGACCTTTGTGAGCAATACCAGATATGACGCAGACCTGGGGGCCCCGTACGTGGACGTGATTT
GTGTGAACAGTTACTTATCCTGGTATCATGACTACGGGCATCTGGAGGTGATTCAGCTGCAGCT
GACTAGCCAGTTTGAGAACTGGTATAAGATGTACCAGAAGCCAATTATCCAGAGCGAGTATGGA
GCAGACGCCGTCTCGGGGCTTCATGAGGATCCACCTCGCATGTTCAGTGAGGAGTACCAGACAG
CTCTCCTGGAGAATTATCATTTGATCCTGGATGAGAAACGAAAAGAATATGTCATCGGAGAGCT
CATCTGGAATTTTGCTGACTTCATGACGAACCAGTCACCACTGAGAGTAACAGGAAACAAGAAG
GGGATCTTCACTCGACAGAGAAACCCCAAGATGGCAGCCTTCATTTTGCGAGAGAGATACTGGA
GGATTGCCAACGAAACCAGAGGTTACGGTTCAGTGCCGAGGACCCAGTGTATGGGAAGCAGACC
GTTCACATTCTAAAGCTACGACTACCTCACCGCAGACAGGGCCTGATGAAGTGAAAGGTATTCT
CTCAGCAGAAGAGTTTTTCCTCTGGAGTTTGTGAACCAACACAAGGGGGACTTTAGAAGTGACA
TGGAAGTTTTCCTTGTGTGGGGATAATGACTTGCAGTGCCTTAGGCTCAGTAATGTGTCCTGCT
GAGAAGTGTCCCAGGTCATTTCTGTCAGGTTTTTTTTGGCCTTGGCTTTGTGTACTCTTGAAAA
CCTACTGTGTGAATACTCACACTAAGAGCTCCTGGTTACCGGCTGAGGGACGGCTCACAATTTA
AGAATACTGACTGTTCTACCAGGGGTTCCAGATTCGATTCCTAGCACCCACGTGGTCGTTAACT
ATGAGCTGTTGCCCCATTTCTCAGGTGATGTACGAACATACATGTGGGGGGAGGGGAATAGTCA
TACGTGTAAAATGAAAATAAATCTAAATAAAACTGTTTTCTTTCATTAT

hide sequence

RefSeq Acc Id:

XM_039089057 ⟹ XP_038944985

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	12	26,701,191 - 26,714,718 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_058711	(Get FASTA)	NCBI Sequence Viewer
	XP_017453744	(Get FASTA)	NCBI Sequence Viewer
	XP_038944985	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAA41228	(Get FASTA)	NCBI Sequence Viewer
	AAP86274	(Get FASTA)	NCBI Sequence Viewer
	CAA68705	(Get FASTA)	NCBI Sequence Viewer
	EDM13475	(Get FASTA)	NCBI Sequence Viewer
	EDM13476	(Get FASTA)	NCBI Sequence Viewer
	P06760	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:	NP_058711 ⟸ NM_017015
- Peptide Label:	precursor
- UniProtKB:	P06760 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MSPRRSVCWFVLGQLLCSCALALQGGMLFPKETPSRELKVLDGLWSFRADYSNNRLQGFEKQWY RQPLRESGPTLDMPVPSSFNDITQEAELRNFIGWVWYEREAVLPQRWTQDTDRRVVLRINSAHY YAVVWVNGIHVVEHEGGHLPFEADITKLVQSGPLTTFRVTIAINNTLTPYTLPPGTIVYKTDPS MYPKGYFVQDISFDFFNYAGLHRSVVLYTTPTTYIDDITVTTDVDRDVGLVNYWISVQGSDHFQ LEVRLLDEDGKIVARGTGNEGQLKVPRAHLWWPYLMHEHPAYLYSLEVTMTTPESVSDFYTLPV GIRTVAVTKSKFLINGKPFYFQGVNKHEDSDIRGRGFDWPLLIKDFNLLRWLGANSFRTSHYPY SEEVLQLCDRYGIVVIDECPGVGIVLPQSFGNVSLRHHLEVMDELVRRDKNHPAVVMWSVANEP VSSLKPAGYYFKTLIAHTKALDPTRPVTFVSNTRYDADMGAPYVDVICVNSYLSWYHDYGHLEV IQLQLTSQFENWYKMYQKPIIQSEYGADAVSGLHEDPPRMFSEEYQTALLENYHLILDEKRKEY VIGELIWNFADFMTNQSPLRVTGNKKGIFTRQRNPKMAAFILRERYWRIANETRGYGSVPRTQC MGSRPFTF hide sequence

RefSeq Acc Id:

XP_017453743 ⟸ XM_017598254

- Peptide Label:

isoform X1

- Sequence:

show sequence

MQLWYPKGYFVQDISFDFFNYAGLHRSVVLYTTPTTYIDDITVTTDVDRDVGLVNYWISVQGSD
HFQLEVRLLDEDGKIVARGTGNEGQLKVPRAHLWWPYLMHEHPAYLYSLEVTMTTPESVSDFYT
LPVGIRTVAVTKSKFLINGKPFYFQGVNKHEDSDIRGRGFDWPLLIKDFNLLRWLGANSFRTSH
YPYSEEVLQLCDRYGIVVIDECPGVGIVLPQSFGNVSLRHHLEVMDELVRRDKNHPAVVMWSVA
NEPVSSLKPAGYYFKTLIAHTKALDPTRPVTFVSNTRYDADLGAPYVDVICVNSYLSWYHDYGH
LEVIQLQLTSQFENWYKMYQKPIIQSEYGADAVSGLHEDPPRMFSEEYQTALLENYHLILDEKR
KEYVIGELIWNFADFMTNQSPLRVTGNKKGIFTRQRNPKMAAFILRERYWRIANETRGYGSVPR
TQCMGSRPFTF

hide sequence

RefSeq Acc Id:

XP_017453744 ⟸ XM_017598255

- Peptide Label:

isoform X2

- Sequence:

show sequence

MDPGHRQESGVENQQRPLLCSCGLVNYWISVQGSDHFQLEVRLLDEDGKIVARGTGNEGQLKVP
RAHLWWPYLMHEHPAYLYSLEVTMTTPESVSDFYTLPVGIRTVAVTKSKFLINGKPFYFQGVNK
HEDSDIRGRGFDWPLLIKDFNLLRWLGANSFRTSHYPYSEEVLQLCDRYGIVVIDECPGVGIVL
PQSFGNVSLRHHLEVMDELVRRDKNHPAVVMWSVANEPVSSLKPAGYYFKTLIAHTKALDPTRP
VTFVSNTRYDADLGAPYVDVICVNSYLSWYHDYGHLEVIQLQLTSQFENWYKMYQKPIIQSEYG
ADAVSGLHEDPPRMFSEEYQTALLENYHLILDEKRKEYVIGELIWNFADFMTNQSPLRVTGNKK
GIFTRQRNPKMAAFILRERYWRIANETRGYGSVPRTQCMGSRPFTF

hide sequence

RefSeq Acc Id:

ENSRNOP00000045033 ⟸ ENSRNOT00000041645

RefSeq Acc Id:

ENSRNOP00000001215 ⟸ ENSRNOT00000001215

RefSeq Acc Id:	XP_038944985 ⟸ XM_039089057
- Peptide Label:	isoform X1

Protein Domains

Glyco_hydro_2 Glyco_hydro_2_C Glyco_hydro_2_N

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13698580

Promoter ID:

EPDNEW_R9105

Type:

initiation region

Name:

Gusb_1

Description:

glucuronidase, beta

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	12	30,202,090 - 30,202,150	EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)

ACI/EurMcwi (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

ACI/EurMcwi (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

ACI/N (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

BBDP/Wor (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

BN/SsN (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Buf/N (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

COP/CrCrl (MCW & UW)

Visual

CSV

TAB

Printer

Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob) University of Wisconsin (Dr. James Shull)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Charles River Laboratories
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)

F344/NCrl (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

F344/NRrrc (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

FHH/EurMcwi (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

FHH/EurMcwi (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

FHL/EurMcwi (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

FHL/EurMcwi (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

GH/OmrMcwi (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

GK/Ox (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LE/Stm (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LEW/Crl (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LEW/NCrlBR (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LH/MavRrrc (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LL/MavRrrc (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LN/MavRrrc (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

M520/N (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

MHS/Gib (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

MNS/Gib (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

MR/N (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

SBH/Ygl (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	SBH/Ygl sequenced by MCW

SBH/Ygl (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SBN/Ygl (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	SBN/Ygl sequenced by MCW

SBN/Ygl (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SHR/NHsd (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SHRSP/Gcrc (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SR/JrHsd (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Harlan Laboratories
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

SR/JrHsd (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SS/Jr (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SS/JrHsdMcwi (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

SS/JrHsdMcwi (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WAG/Rij (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/Gcrc (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/N (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

WKY/NCrl (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/NHsd (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WN/N (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:2772	AgrOrtholog
Ensembl Genes	ENSRNOG00000000913	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000001215	ENTREZGENE, UniProtKB/TrEMBL
	ENSRNOP00000045033	UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000001215	ENTREZGENE, UniProtKB/TrEMBL
	ENSRNOT00000041645	UniProtKB/TrEMBL
Gene3D-CATH	2.60.120.260	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	2.60.40.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro	Beta-gal/glucu_dom_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Galactose-bd-like_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Glyco_hydro_2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Glyco_hydro_2_AS	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Glyco_hydro_2_cat	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Glyco_hydro_2_CS	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Glyco_hydro_2_Ig-like	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Glyco_hydro_2_N	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Glycoside_hydrolase_SF	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Ig-like_fold	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:24434	UniProtKB/Swiss-Prot
NCBI Gene	24434	ENTREZGENE
Pfam	Glyco_hydro_2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Glyco_hydro_2_C	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Glyco_hydro_2_N	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Gusb	PhenoGen
PRINTS	GLHYDRLASE2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE	GLYCOSYL_HYDROL_F2_1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	GLYCOSYL_HYDROL_F2_2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	SSF49303	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SSF49785	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SSF51445	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	BGLR_RAT	UniProtKB/Swiss-Prot
	F1LQQ8_RAT	UniProtKB/TrEMBL
	P06760	ENTREZGENE
	Q7TPJ3_RAT	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2002-06-10	Gusb	Glucuronidase, beta			Symbol and Name status set to approved	70586	APPROVED

RGD Curation Notes

Note Type	Note	Reference
gene_disease	mutation of the human homolog causes mucopolysaccharidosis type VII	731201

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

Imported Annotations - SMPDB

Imported Annotations - KEGG (archival)

Send us a Message

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

Imported Annotations - SMPDB

Imported Annotations - KEGG (archival)