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Gene: Gusb (glucuronidase, beta) Rattus norvegicus
Symbol: Gusb
Name: glucuronidase, beta
Description: Exhibits beta-glucuronidase activity and carbohydrate binding activity. Predicted to be involved in glucuronoside catabolic process. Localizes to the lysosome. Human ortholog(s) of this gene implicated in Sly syndrome. Orthologous to human GUSB (glucuronidase beta); PARTICIPATES IN acute intermittent porphyria pathway; congenital sucrase-isomaltase deficiency pathway; erythropoietic porphyria pathway; INTERACTS WITH (-)-epigallocatechin 3-gallate; (R)-lipoic acid; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Ac2-223; beta-glucuronidase; Gus-s
Homo sapiens (human) : GUSB (glucuronidase beta)  HGNC  Alliance
Mus musculus (house mouse) : Gusb (glucuronidase, beta)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gusb (glucuronidase beta)
Pan paniscus (bonobo/pygmy chimpanzee) : GUSB (glucuronidase beta)
Canis lupus familiaris (dog) : GUSB (glucuronidase beta)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gusb (glucuronidase beta)
Sus scrofa (pig) : GUSB (glucuronidase beta)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01230,202,066 - 30,215,583 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01232,139,367 - 32,152,883 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41227,744,409 - 27,757,755 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11227,607,658 - 27,620,971 (+)NCBI
Celera1228,414,852 - 28,428,552 (+)NCBICelera
Cytogenetic Map12q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Gusb
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2772
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.