Gusb (glucuronidase, beta) - Rat Genome Database

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Gene: Gusb (glucuronidase, beta) Mus musculus
Analyze
Symbol: Gusb
Name: glucuronidase, beta
RGD ID: 1557024
MGI Page MGI
Description: Enables beta-glucuronidase activity. Involved in chondroitin sulfate catabolic process; heparan sulfate proteoglycan catabolic process; and hyaluronan catabolic process. Acts upstream of or within glucuronoside catabolic process. Located in extracellular space. Is active in lysosomal lumen. Is expressed in several structures, including alimentary system; brain; heart; sensory organ; and viscerocranium. Used to study Sly syndrome. Human ortholog(s) of this gene implicated in Sly syndrome. Orthologous to human GUSB (glucuronidase beta).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: a; adipose storage deficiency; AI747421; asd; beta-glucuronidase; g; Gu; Gur; Gus; Gus-; Gus-r; Gus-s; Gus-t; Gus-u; Gut
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395130,011,278 - 130,031,890 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5130,017,852 - 130,031,890 (-)EnsemblGRCm39 Ensembl
GRCm385129,989,011 - 130,003,049 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5129,989,011 - 130,003,049 (-)EnsemblGRCm38mm10GRCm38
MGSCv375130,464,891 - 130,478,698 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365130,273,724 - 130,287,531 (-)NCBIMGSCv36mm8
Celera5126,991,862 - 127,006,971 (-)NCBICelera
Cytogenetic Map5G1.3NCBI
cM Map568.32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (ISO)
(-)-epigallocatechin 3-gallate  (ISO)
(R)-lipoic acid  (ISO)
(R,R,R)-alpha-tocopherol  (EXP)
1,1-dichloroethene  (EXP)
1,2-dimethylhydrazine  (EXP)
17beta-estradiol  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (ISO)
2,6-dinitrotoluene  (ISO)
2-acetyl-1-alkyl-sn-glycero-3-phosphocholine  (ISO)
3-chloropropane-1,2-diol  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-diaminodiphenylmethane  (EXP)
4-\{[(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)carbonyl]amino\}benzoic acid  (ISO)
4-hydroxyphenyl retinamide  (EXP)
5-aza-2'-deoxycytidine  (EXP)
acrolein  (ISO)
acrylamide  (EXP,ISO)
aflatoxin B1  (EXP)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
amlodipine  (ISO)
ammonium chloride  (ISO)
anthocyanin  (ISO)
atrazine  (ISO)
benoxaprofen  (ISO)
benzene  (ISO)
benzo[a]pyrene  (EXP,ISO)
bisphenol A  (EXP,ISO)
carbamazepine  (ISO)
carbon nanotube  (EXP)
choline  (EXP)
chromium(6+)  (ISO)
cis-caffeic acid  (ISO)
cobalt dichloride  (ISO)
compound 48/80  (ISO)
cumene hydroperoxide  (EXP)
Cuprizon  (ISO)
curcumin  (ISO)
cyclophosphamide  (ISO)
cytochalasin B  (ISO)
D-mannopyranose 6-phosphate  (ISO)
D-mannose 6-phosphate  (ISO)
dexamethasone  (EXP,ISO)
dibutyl phthalate  (ISO)
diethylstilbestrol  (EXP)
divanadium pentaoxide  (EXP)
doxorubicin  (EXP,ISO)
ellagic acid  (ISO)
endosulfan  (ISO)
ethanol  (EXP,ISO)
ethyl methanesulfonate  (ISO)
fenvalerate  (EXP)
ferulic acid  (ISO)
Fexofenadine hydrochloride  (ISO)
flavonoids  (ISO)
flurbiprofen  (EXP)
flutamide  (ISO)
folic acid  (EXP)
gamma-hexachlorocyclohexane  (ISO)
genistein  (EXP,ISO)
gentamycin  (ISO)
glafenine  (ISO)
glycine betaine  (ISO)
histamine  (ISO)
indometacin  (ISO)
isoprenaline  (ISO)
ivermectin  (ISO)
L-ascorbic acid  (ISO)
L-methionine  (EXP)
lipoic acid  (ISO)
lipopolysaccharide  (EXP,ISO)
mangiferin  (ISO)
menadione  (ISO)
methoxychlor  (ISO)
methyl methanesulfonate  (ISO)
myrtenal  (ISO)
N,O-dimethyltyramine  (ISO)
N-formyl-L-methionyl-L-leucyl-L-phenylalanine  (ISO)
N-nitrosodiethylamine  (ISO)
naringin  (ISO)
nefazodone  (ISO)
nickel dichloride  (ISO)
nicorandil  (ISO)
ozone  (EXP,ISO)
paclitaxel  (ISO)
paracetamol  (EXP,ISO)
parathion  (EXP)
parathion-methyl  (ISO)
phenobarbital  (ISO)
phenytoin  (EXP)
picoxystrobin  (ISO)
pirinixic acid  (ISO)
potassium chromate  (ISO)
potassium dichromate  (ISO)
resveratrol  (EXP)
S-allylcysteine  (ISO)
selenic acid  (ISO)
silver atom  (EXP)
silver(0)  (EXP)
sodium arsenite  (ISO)
Soman  (ISO)
sunitinib  (ISO)
suramin  (ISO)
tert-butyl hydroperoxide  (ISO)
tetrachloromethane  (EXP,ISO)
titanium dioxide  (EXP)
trans-caffeic acid  (ISO)
Triptolide  (EXP)
valproic acid  (ISO)
vancomycin  (EXP)
vincaleukoblastine  (ISO)
vinclozolin  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Actinomycin D peritonitis in the rat. Arrigoni-Martelli E, Fed Proc. 1976 Nov;35(13):2457-7.
2. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
3. MGDs mouse GO annotations MGD data from the GO Consortium
4. MGD IEA MGD IEA
5. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
6. Online Mendelian Inheritance in Man, OMIM (TM). Online Mendelian Inheritance in Man, OMIM (TM).
7. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
8. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
9. The suramin-treated rat as a model of mucopolysaccharidosis. Variation in the reversibility of biochemical and morphological changes among different organs. Rees S, etal., Virchows Arch B Cell Pathol Incl Mol Pathol. 1986;52(3):259-72. doi: 10.1007/BF02889967.
10. Mouse MP Annotation Import Pipeline RGD automated import pipeline
11. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
12. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
13. Effect of concurrent administration of aspirin, indomethacin or hydrocortisone with gold sodium thiomalate against adjuvant-induced arthritis in the rat. Sofia DR, etal., Agents Actions. 1976 Nov;6(6):728-34. doi: 10.1007/BF02026096.
Additional References at PubMed
PMID:219475   PMID:231933   PMID:701256   PMID:743194   PMID:744474   PMID:760204   PMID:849251   PMID:942653   PMID:1123410   PMID:1203052   PMID:1311971   PMID:1315306  
PMID:1338772   PMID:1372902   PMID:1387105   PMID:1522559   PMID:1535334   PMID:1543915   PMID:1647018   PMID:1683707   PMID:1686571   PMID:1794058   PMID:1869533   PMID:1914521  
PMID:1954394   PMID:1968044   PMID:1970330   PMID:1974892   PMID:1979024   PMID:2111021   PMID:2159567   PMID:2165966   PMID:2264930   PMID:2328987   PMID:2328989   PMID:2383242  
PMID:2394691   PMID:2448782   PMID:2495302   PMID:2563387   PMID:2565278   PMID:2571572   PMID:2712823   PMID:2779578   PMID:2787378   PMID:2835664   PMID:2838410   PMID:2891607  
PMID:3182771   PMID:3196706   PMID:3200849   PMID:3397060   PMID:3478306   PMID:3732791   PMID:3840761   PMID:4042679   PMID:4726445   PMID:4771317   PMID:4777306   PMID:4841576  
PMID:5289439   PMID:5705828   PMID:6111546   PMID:6242882   PMID:6278049   PMID:6308669   PMID:6459778   PMID:6576346   PMID:6689271   PMID:6774020   PMID:6980940   PMID:7115285  
PMID:7203014   PMID:7204385   PMID:7354065   PMID:7579886   PMID:7684230   PMID:7744842   PMID:7777557   PMID:7789186   PMID:7789995   PMID:7808217   PMID:7829060   PMID:7885477  
PMID:7896269   PMID:7933993   PMID:7970933   PMID:7983353   PMID:8007964   PMID:8032683   PMID:8043948   PMID:8083358   PMID:8094303   PMID:8101990   PMID:8108204   PMID:8111123  
PMID:8119157   PMID:8119734   PMID:8144516   PMID:8200966   PMID:8254755   PMID:8288233   PMID:8348154   PMID:8380915   PMID:8513128   PMID:8603775   PMID:8666393   PMID:8812449  
PMID:8827514   PMID:8889548   PMID:8903730   PMID:8938452   PMID:9037045   PMID:9321482   PMID:9344682   PMID:9383292   PMID:9521879   PMID:9525982   PMID:9774663   PMID:9881957  
PMID:10051313   PMID:10051635   PMID:10067860   PMID:10074197   PMID:10211958   PMID:10349636   PMID:10383162   PMID:10433265   PMID:10438476   PMID:10459853   PMID:10477745   PMID:10491617  
PMID:10560917   PMID:10613847   PMID:10630187   PMID:10630195   PMID:10724030   PMID:10832732   PMID:10922068   PMID:11040082   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11226217  
PMID:11228259   PMID:11273777   PMID:11571571   PMID:11783949   PMID:11856642   PMID:12121741   PMID:12403825   PMID:12406886   PMID:12439624   PMID:12466851   PMID:12477932   PMID:12700165  
PMID:13732096   PMID:14276177   PMID:14483211   PMID:14556521   PMID:14583446   PMID:14610273   PMID:14681479   PMID:14684827   PMID:14705966   PMID:15782199   PMID:16141072   PMID:16141073  
PMID:16515890   PMID:16602821   PMID:16754748   PMID:17015822   PMID:17911106   PMID:18607772   PMID:19017790   PMID:19375967   PMID:19710420   PMID:19723663   PMID:19749771   PMID:19751987  
PMID:20018674   PMID:20385825   PMID:21267068   PMID:21670277   PMID:21670299   PMID:21873635   PMID:21944884   PMID:22403656   PMID:23412092   PMID:23897660   PMID:24334460   PMID:24859337  
PMID:24952961   PMID:25559179   PMID:26170381   PMID:27053151   PMID:27301070   PMID:27692945   PMID:28564958   PMID:28872463   PMID:29514215   PMID:30550785   PMID:32102934   PMID:32325033  


Genomics

Comparative Map Data
Gusb
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395130,011,278 - 130,031,890 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5130,017,852 - 130,031,890 (-)EnsemblGRCm39 Ensembl
GRCm385129,989,011 - 130,003,049 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5129,989,011 - 130,003,049 (-)EnsemblGRCm38mm10GRCm38
MGSCv375130,464,891 - 130,478,698 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365130,273,724 - 130,287,531 (-)NCBIMGSCv36mm8
Celera5126,991,862 - 127,006,971 (-)NCBICelera
Cytogenetic Map5G1.3NCBI
cM Map568.32NCBI
GUSB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38765,960,684 - 65,982,213 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl765,960,684 - 65,982,215 (-)EnsemblGRCh38hg38GRCh38
GRCh37765,425,671 - 65,447,200 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36765,063,106 - 65,084,681 (-)NCBINCBI36Build 36hg18NCBI36
Build 34764,869,824 - 64,891,346NCBI
Celera766,666,375 - 66,688,005 (+)NCBICelera
Cytogenetic Map7q11.21NCBI
HuRef761,613,080 - 61,634,635 (-)NCBIHuRef
CHM1_1765,520,933 - 65,542,533 (-)NCBICHM1_1
T2T-CHM13v2.0767,182,808 - 67,204,306 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2764,763,190 - 64,784,820 (-)NCBI
Gusb
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21226,701,191 - 26,714,718 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1226,697,951 - 26,726,905 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1227,848,970 - 27,862,457 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.01228,459,495 - 28,472,985 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01227,520,988 - 27,534,476 (+)NCBIRnor_WKY
Rnor_6.01230,202,066 - 30,215,583 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1230,198,822 - 30,227,771 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01232,139,367 - 32,152,883 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41227,744,409 - 27,757,755 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11227,607,658 - 27,620,971 (+)NCBI
Celera1228,414,852 - 28,428,552 (+)NCBICelera
Cytogenetic Map12q12NCBI
Gusb
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554568,378,654 - 8,392,252 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554568,377,161 - 8,392,298 (-)NCBIChiLan1.0ChiLan1.0
GUSB
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1764,724,628 - 64,745,040 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl764,724,841 - 64,744,909 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0760,087,130 - 60,109,289 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
GUSB
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.16730,345 - 743,916 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl6730,358 - 779,424 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha62,430,980 - 2,444,321 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.06535,764 - 548,724 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl6535,765 - 549,610 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.16479,152 - 492,513 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.06473,517 - 486,454 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.06644,508 - 657,770 (-)NCBIUU_Cfam_GSD_1.0
Gusb
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344126,304,099 - 126,314,709 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049365437,721,273 - 7,732,468 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GUSB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl316,671,389 - 16,689,203 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1316,672,071 - 16,686,520 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2316,924,697 - 16,939,444 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103246571
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1281,621,293 - 1,646,097 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl281,620,359 - 1,646,075 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607015,002,837 - 15,024,286 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gusb
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247408,390,197 - 8,401,387 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247408,390,096 - 8,401,063 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Position Markers
AI747421  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm385129,989,383 - 129,989,495UniSTSGRCm38
MGSCv375130,465,253 - 130,465,365UniSTSGRCm37
Celera5126,992,224 - 126,992,336UniSTS
Cytogenetic Map5G1.3UniSTS
Whitehead/MRC_RH51566.13UniSTS
D5Mit27  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm385130,000,063 - 130,000,203UniSTSGRCm38
MGSCv375130,475,933 - 130,476,073UniSTSGRCm37
Celera5127,004,208 - 127,004,346UniSTS
Celera5127,002,895 - 127,004,346UniSTS
Cytogenetic Map5G1.3UniSTS
cM Map572.0UniSTS
Whitehead Genetic562.3UniSTS
PMC151849P1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm385129,989,643 - 129,990,053UniSTSGRCm38
MGSCv375130,465,513 - 130,465,923UniSTSGRCm37
Celera5126,992,484 - 126,992,894UniSTS
Cytogenetic Map5G1.3UniSTS
Gus-s  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm385130,000,043 - 130,000,205UniSTSGRCm38
MGSCv375130,475,913 - 130,476,075UniSTSGRCm37
Celera5127,002,877 - 127,004,348UniSTS
Celera5127,004,188 - 127,004,348UniSTS
Cytogenetic Map5G1.3UniSTS
cM Map572.0UniSTS
Gus-s  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map5G1.3UniSTS
cM Map572.0UniSTS


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
11341716Rvfs3_mRift Valley fever susceptibility 3 (mouse)526441234138455402Mouse
26884395Humsd2_mhumerus midshaft diameter 2, 10 week (mouse)570057343132528839Mouse
27226719Tibw6_mtibia width 6, proximal, 16 week (mouse)572857343139985755Mouse
25314315Mlh1fc4_mMLH1 foci count 4 (mouse)574460661132528839Mouse
13506928Recrq8_mrecombination rate in male meiosis QTL 8 (mouse)574460661132528839Mouse
1301362Prnr1_mprion resistance 1 (mouse)Not determined589418876146787935Mouse
1300940Actd3_mactivity-distance traveled 3 (mouse)Not determined596320385130320533Mouse
1300659Pcd8ts1_mp-glycoprotein positive CD8 T cell subset 1 (mouse)Not determined597021753131021986Mouse
1301858Smdq1_msegregation of mitochondrial DNA QTL 1 (mouse)Not determined597021753131021986Mouse
12904945Tammq2_mtibialis anterior muscle mass QTL 2 (mouse)5100665965134665965Mouse
12904959Smmq1_msoleus muscle mass QTL 1 (mouse)5100665965134665965Mouse
12859290Criq2_mCitrobacter rodentium infection QTL 2 (mouse)5101332579135332579Mouse
1301624Aevm2_mautoimmune extremity vasculitis in MRL mice 2 (mouse)Not determined5101863832135864028Mouse
14746986Manh58_mmandible shape 58 (mouse)5102446283136446283Mouse
11532736Sluc33b_msusceptibility to lung cancer 33b (mouse)5102945037136945196Mouse
10412202Bbaa26_mB.burgdorferi-associated arthritis 26 (mouse)Not determined5104583688138555455Mouse
10412239Alpq7_malcohol preference QTL 7 (mouse)Not determined5104705939138705939Mouse
10043890Trigq4_mtriglyceride QTL 4 (mouse)Not determined5107906299141906412Mouse
4142473Chlq11_mcirculating hormone level QTL 11 (mouse)Not determined5107906299141906412Mouse
13464243Ahl20_mage related hearing loss, early onset 20 (mouse)5107906299141906412Mouse
10412197Bbaa25_mB.burgdorferi-associated arthritis 25 (mouse)Not determined5109167240143167381Mouse
13464251Ahl21_mage related hearing loss, early onset 21 (mouse)5109167240143167381Mouse
1301543Hypch_mhypercholesterolemia (mouse)Not determined5109238624139118905Mouse
1300913Bwefm_mbody weight females and males day 10 (mouse)Not determined5109439348143439459Mouse
1301102Cia14_mcollagen induced arthritis 14 (mouse)Not determined5113320385138555455Mouse
1301226Bbaa2_mB.burgdorferi-associated arthritis 2 (mouse)Not determined5115156883149157015Mouse
1300827Cora1_mcorrelation in cytokine production 1 (mouse)Not determined5115156883149157015Mouse
1301857Bglq14_mbody growth late QTL 14 (mouse)Not determined5118948964151758149Mouse
10412191Bbaa24_mB.burgdorferi-associated arthritis 24 (mouse)Not determined5119945037141700466Mouse
4141081Nidd7k_mNidd7 on KK-A (mouse)Not determined119945037149347326Mouse
11528552Scram1_mspinal cord resistance to astrocytoma modifier 1 (mouse)5121455402151758149Mouse
1301986Bpq4_mblood pressure QTL 4 (mouse)Not determined5121555236151758149Mouse
1302079Lbw3_mlupus NZB x NZW 3 (mouse)Not determined5124700335151758149Mouse
1301363Pbwg13_mpostnatal body weight growth 13 (mouse)Not determined5125133457151758149Mouse
1301715Elmaz2_melevated maze behavior 2 (mouse)Not determined5125178229141700466Mouse
13464142Bbaa2a_mB.burgdorferi-associated arthritis 2a (mouse)5128571199130052971Mouse
4141218Ath24_matherosclerosis 24 (mouse)Not determined129520084151758149Mouse
12880406Jcdq2_mjoint cartilage degeneration QTL 2 (mouse)5129787831151758149Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1099
Count of miRNA genes:550
Interacting mature miRNAs:659
Transcripts:ENSMUST00000026613, ENSMUST00000111307, ENSMUST00000111308, ENSMUST00000122994, ENSMUST00000126676
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001357025 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001357026 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001357027 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_010368 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011240853 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_377102 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC161345 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI325302 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK002832 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK041058 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK076109 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK136519 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK146247 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK149814 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK150048 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK151802 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK152206 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK159163 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK159526 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK159564 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK159804 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK162436 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK185900 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK186936 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK208599 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK214954 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK218909 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC004616 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC018202 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC071226 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466529 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  J02836 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  J03047 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M19279 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M28540 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M28541 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M63836 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U53134 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000026613   ⟹   ENSMUSP00000026613
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5130,017,852 - 130,031,890 (-)Ensembl
GRCm38.p6 Ensembl5129,989,011 - 130,003,049 (-)Ensembl
RefSeq Acc Id: ENSMUST00000111307   ⟹   ENSMUSP00000106939
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5130,028,440 - 130,031,722 (-)Ensembl
GRCm38.p6 Ensembl5129,999,599 - 130,002,881 (-)Ensembl
RefSeq Acc Id: ENSMUST00000111308   ⟹   ENSMUSP00000106940
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5130,027,500 - 130,031,706 (-)Ensembl
GRCm38.p6 Ensembl5129,998,659 - 130,002,865 (-)Ensembl
RefSeq Acc Id: ENSMUST00000122994
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5130,028,463 - 130,031,806 (-)Ensembl
GRCm38.p6 Ensembl5129,999,622 - 130,002,965 (-)Ensembl
RefSeq Acc Id: ENSMUST00000126676
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5130,018,422 - 130,019,483 (-)Ensembl
GRCm38.p6 Ensembl5129,989,581 - 129,990,642 (-)Ensembl
RefSeq Acc Id: ENSMUST00000201801   ⟹   ENSMUSP00000144478
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5130,017,864 - 130,031,669 (-)Ensembl
GRCm38.p6 Ensembl5129,989,023 - 130,002,828 (-)Ensembl
RefSeq Acc Id: NM_001357025   ⟹   NP_001343954
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395130,017,852 - 130,031,890 (-)NCBI
GRCm385129,989,011 - 130,003,049 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001357026   ⟹   NP_001343955
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395130,028,441 - 130,031,890 (-)NCBI
GRCm385129,999,600 - 130,003,049 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001357027   ⟹   NP_001343956
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395130,028,441 - 130,031,890 (-)NCBI
GRCm385129,999,600 - 130,003,049 (-)NCBI
Sequence:
RefSeq Acc Id: NM_010368   ⟹   NP_034498
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395130,017,852 - 130,031,890 (-)NCBI
GRCm385129,989,011 - 130,003,049 (-)NCBI
MGSCv375130,464,891 - 130,478,698 (-)RGD
Celera5126,991,862 - 127,006,971 (-)RGD
cM Map5 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_011240853   ⟹   XP_011239155
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395130,011,278 - 130,029,664 (-)NCBI
GRCm385129,989,011 - 130,000,823 (-)NCBI
Sequence:
RefSeq Acc Id: XR_377102
RefSeq Status:
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395130,011,278 - 130,031,885 (-)NCBI
GRCm385129,989,011 - 130,003,044 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_034498   ⟸   NM_010368
- Peptide Label: isoform 1 precursor
- UniProtKB: Q6IR10 (UniProtKB/Swiss-Prot),   P12265 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_011239155   ⟸   XM_011240853
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: NP_001343954   ⟸   NM_001357025
- Peptide Label: isoform 2
RefSeq Acc Id: NP_001343956   ⟸   NM_001357027
- Peptide Label: isoform 4 precursor
- UniProtKB: D3YY48 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001343955   ⟸   NM_001357026
- Peptide Label: isoform 3 precursor
- UniProtKB: Q99KJ6 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSMUSP00000106939   ⟸   ENSMUST00000111307
RefSeq Acc Id: ENSMUSP00000106940   ⟸   ENSMUST00000111308
RefSeq Acc Id: ENSMUSP00000026613   ⟸   ENSMUST00000026613
RefSeq Acc Id: ENSMUSP00000144478   ⟸   ENSMUST00000201801
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P12265-F1-model_v2 AlphaFold P12265 1-648 view protein structure

Promoters
RGD ID:6849920
Promoter ID:EP30088
Type:single initiation site
Name:MM_BGLR
Description:beta-glucuronidase, GUSB or GUS or GUS-S gene.
SO ACC ID:SO:0000170
Source:EPD (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Nuclease protection; Primer extension
Regulation:kidney( (induced by or strongly expressed in) androgen)
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36Un2,301 - 2,361EPD
RGD ID:6888204
Promoter ID:EPDNEW_M7553
Type:initiation region
Name:Gusb_1
Description:Mus musculus glucuronidase, beta , transcript variant 3, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm385130,002,828 - 130,002,888EPDNEW
RGD ID:6837687
Promoter ID:MM_KWN:44228
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day2,   BoneMarrow_0Hour
Transcripts:OTTMUST00000058841
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv365130,466,161 - 130,466,912 (-)MPROMDB
RGD ID:6837686
Promoter ID:MM_KWN:44229
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000026614,   ENSMUST00000111308,   OTTMUST00000058837,   OTTMUST00000058838,   UC008ZTU.1,   UC008ZTW.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv365130,478,444 - 130,478,944 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:95872 AgrOrtholog
Ensembl Genes ENSMUSG00000025534 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000026613 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000106939 ENTREZGENE
  ENSMUSP00000106939.2 UniProtKB/TrEMBL
  ENSMUSP00000106940 ENTREZGENE
  ENSMUSP00000106940.2 UniProtKB/TrEMBL
  ENSMUSP00000144478.2 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000026613 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000111307 ENTREZGENE
  ENSMUST00000111307.2 UniProtKB/TrEMBL
  ENSMUST00000111308 ENTREZGENE
  ENSMUST00000111308.8 UniProtKB/TrEMBL
  ENSMUST00000201801.4 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Beta-gal/glucu_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Galactose-bd-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Glyco_hydro_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Glyco_hydro_2_AS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Glyco_hydro_2_cat UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Glyco_hydro_2_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Glyco_hydro_2_Ig-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Glyco_hydro_2_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Glycoside_hydrolase_SF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:110006 UniProtKB/Swiss-Prot
MGD MGI:95872 ENTREZGENE
NCBI Gene 110006 ENTREZGENE
Pfam Glyco_hydro_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Glyco_hydro_2_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Glyco_hydro_2_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Gusb PhenoGen
PRINTS GLHYDRLASE2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE GLYCOSYL_HYDROL_F2_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GLYCOSYL_HYDROL_F2_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF49303 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF49785 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF51445 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt BGLR_MOUSE UniProtKB/Swiss-Prot
  D3YY48 ENTREZGENE, UniProtKB/TrEMBL
  P12265 ENTREZGENE
  Q3TW82_MOUSE UniProtKB/TrEMBL
  Q6IR10 ENTREZGENE
  Q8BPE3_MOUSE UniProtKB/TrEMBL
  Q8VEM0_MOUSE UniProtKB/TrEMBL
  Q99KJ6 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary Q61601 UniProtKB/Swiss-Prot
  Q64473 UniProtKB/Swiss-Prot
  Q64474 UniProtKB/Swiss-Prot
  Q6IR10 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-29 Gusb  glucuronidase, beta  Gus  beta-glucuronidase  Data Merged 737654 PROVISIONAL