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Gene: Gusb (glucuronidase, beta) Mus musculus
Symbol: Gusb
Name: glucuronidase, beta
Description: Exhibits beta-glucuronidase activity. Involved in glucuronoside catabolic process. Localizes to the extracellular space and lysosome. Used to study Sly syndrome. Human ortholog(s) of this gene implicated in Sly syndrome. Is expressed in several structures, including alimentary system; brain; heart; sensory organ; and viscerocranium. Orthologous to human GUSB (glucuronidase beta); PARTICIPATES IN acute intermittent porphyria pathway; congenital sucrase-isomaltase deficiency pathway; erythropoietic porphyria pathway; INTERACTS WITH (+)-alpha-tocopherol; 1,1-dichloroethene; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: adipose storage deficiency; AI747421; asd; beta-glucuronidase; g; Gur; Gus; Gus-r; Gus-s; Gus-t; Gus-u; Gut
Homo sapiens (human) : GUSB (glucuronidase beta)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Gusb (glucuronidase, beta)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gusb (glucuronidase beta)
Pan paniscus (bonobo/pygmy chimpanzee) : GUSB (glucuronidase beta)
Canis lupus familiaris (dog) : GUSB (glucuronidase beta)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gusb (glucuronidase beta)
Sus scrofa (pig) : GUSB (glucuronidase beta)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm385129,989,011 - 130,003,049 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv375130,464,891 - 130,478,698 (-)NCBIGRCm37mm9NCBIm37
MGSCv365130,273,724 - 130,287,531 (-)NCBImm8
Celera5126,991,862 - 127,006,971 (-)NCBICelera
Cytogenetic Map5 G1.3NCBI
cM Map568.32NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Gusb
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1557024
Created: 2005-11-30
Species: Mus musculus
Last Modified: 2019-10-29
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.