Cers4 (ceramide synthase 4) - Rat Genome Database

Name: Cers4
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: Cers4 (ceramide synthase 4) Rattus norvegicus

Analyze

Symbol:

Cers4

Name:

ceramide synthase 4

RGD ID:

1309303

Description:

Predicted to enable sphingosine N-acyltransferase activity. Predicted to be involved in ceramide biosynthetic process. Predicted to act upstream of or within sphingolipid biosynthetic process. Predicted to be located in endoplasmic reticulum. Orthologous to human CERS4 (ceramide synthase 4); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; 6-propyl-2-thiouracil.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

LAG1 homolog, ceramide synthase 4; LAG1 longevity assurance homolog 4; Lass4; LOC304208; longevity assurance homolog 4; longevity assurance homolog 4 (S. cerevisiae)

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	CERS4 (ceramide synthase 4)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Cers4 (ceramide synthase 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Cers4 (ceramide synthase 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	CERS4 (ceramide synthase 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	CERS4 (ceramide synthase 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Cers4 (ceramide synthase 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	CERS4 (ceramide synthase 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	CERS4 (ceramide synthase 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Cers4 (ceramide synthase 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	CERS4 (ceramide synthase 4)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Cers4 (ceramide synthase 4)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	cers4a (ceramide synthase 4a)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OrthoFinder\|PANTHER)
Danio rerio (zebrafish):	cers4b (ceramide synthase 4b)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OrthoFinder\|PANTHER\|PhylomeDB)
Saccharomyces cerevisiae (baker's yeast):	LAC1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	LAG1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	hyl-2	Alliance	DIOPT (InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	schlank	Alliance	DIOPT (OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	12	2,851,784 - 2,890,244 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	12	2,851,784 - 2,886,828 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	12	3,499,944 - 3,534,889 (+)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	12	4,123,536 - 4,158,481 (+)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	12	2,887,342 - 2,922,582 (+)	NCBI	Rnor_WKY
Rnor_6.0	12	4,439,750 - 4,474,759 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	12	4,439,750 - 4,474,729 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	12	6,568,235 - 6,602,867 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	12	1,256,396 - 1,291,578 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	12	1,257,772 - 1,290,757 (-)	NCBI
Celera	12	4,665,718 - 4,700,469 (+)	NCBI		Celera
Cytogenetic Map	12	p12	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autistic disorder (ISO)

familial hemophagocytic lymphohistiocytosis 5 (ISO)

genetic disease (ISO)

mucolipidosis type IV (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

17beta-estradiol (ISO)

2,2',4,4',5,5'-hexachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2-hydroxypropanoic acid (ISO)

3,4-methylenedioxymethamphetamine (ISO)

4,4'-diaminodiphenylmethane (ISO)

4,4'-sulfonyldiphenol (EXP)

4-hydroxyphenyl retinamide (ISO)

6-propyl-2-thiouracil (EXP)

aflatoxin B1 (ISO)

Aflatoxin B2 alpha (ISO)

amphetamine (EXP)

arsane (ISO)

arsenic atom (ISO)

arsenous acid (ISO)

benzo[a]pyrene (ISO)

benzo[e]pyrene (ISO)

bisphenol A (EXP,ISO)

bisphenol F (EXP)

cadmium atom (ISO)

cadmium dichloride (EXP)

caffeine (ISO)

carbon nanotube (ISO)

cisplatin (ISO)

copper(II) sulfate (ISO)

cyclosporin A (ISO)

diarsenic trioxide (ISO)

dibutyl phthalate (EXP,ISO)

doxorubicin (ISO)

folic acid (ISO)

gentamycin (EXP)

GW 4064 (ISO)

isotretinoin (ISO)

lead diacetate (ISO)

methapyrilene (ISO)

mitomycin C (ISO)

N-nitrosodiethylamine (EXP)

paracetamol (ISO)

perfluorooctanoic acid (ISO)

phenethyl caffeate (ISO)

phosgene (ISO)

phytoestrogen (ISO)

pirinixic acid (ISO)

potassium chromate (ISO)

rac-lactic acid (ISO)

resveratrol (ISO)

silicon dioxide (ISO)

sodium arsenate (ISO)

sodium arsenite (ISO)

succimer (ISO)

titanium dioxide (ISO)

trichloroethene (EXP)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

ceramide biosynthetic process (IBA,ISO)

sphingolipid biosynthetic process (ISO)

Cellular Component

endoplasmic reticulum (ISO)

endoplasmic reticulum membrane (IEA)

nucleus (IEA)

Molecular Function

DNA binding (IEA)

protein binding (ISO)

sphingosine N-acyltransferase activity (IBA,ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12912983	PMID:15823095	PMID:17977534	PMID:29632068

Genomics

Comparative Map Data

Cers4
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	12	2,851,784 - 2,890,244 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	12	2,851,784 - 2,886,828 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	12	3,499,944 - 3,534,889 (+)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	12	4,123,536 - 4,158,481 (+)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	12	2,887,342 - 2,922,582 (+)	NCBI	Rnor_WKY
Rnor_6.0	12	4,439,750 - 4,474,759 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	12	4,439,750 - 4,474,729 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	12	6,568,235 - 6,602,867 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	12	1,256,396 - 1,291,578 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	12	1,257,772 - 1,290,757 (-)	NCBI
Celera	12	4,665,718 - 4,700,469 (+)	NCBI		Celera
Cytogenetic Map	12	p12	NCBI

CERS4
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	19	8,209,370 - 8,262,421 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p13 Ensembl	19	8,206,736 - 8,262,421 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	19	8,274,254 - 8,327,305 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	8,180,257 - 8,233,302 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	19	8,180,256 - 8,233,302	NCBI
Celera	19	8,145,624 - 8,198,703 (+)	NCBI		Celera
Cytogenetic Map	19	p13.2	NCBI
HuRef	19	7,944,374 - 7,996,205 (+)	NCBI		HuRef
CHM1_1	19	8,273,682 - 8,326,785 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	19	8,210,805 - 8,263,817 (+)	NCBI		T2T-CHM13v2.0

Cers4
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	8	4,542,863 - 4,579,603 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	8	4,543,026 - 4,581,680 (+)	Ensembl		GRCm39 Ensembl
GRCm38	8	4,492,818 - 4,529,603 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	8	4,493,026 - 4,531,680 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	8	4,493,405 - 4,526,079 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	8	4,493,504 - 4,525,757 (+)	NCBI		MGSCv36	mm8
Celera	8	4,687,834 - 4,720,521 (+)	NCBI		Celera
Cytogenetic Map	8	A1.1	NCBI

Cers4
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955563	1,100,787 - 1,124,258 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955563	1,100,410 - 1,105,662 (-)	NCBI	ChiLan1.0	ChiLan1.0

CERS4
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	19	8,364,569 - 8,415,345 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	19	8,364,569 - 8,415,345 (+)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	19	7,509,213 - 7,562,394 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3

CERS4
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	20	52,829,482 - 52,860,783 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	20	52,829,316 - 52,860,803 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	20	52,630,184 - 52,662,189 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	20	53,356,351 - 53,388,350 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	20	53,357,348 - 53,388,669 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	20	52,559,172 - 52,591,152 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	20	53,004,363 - 53,036,367 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	20	53,235,869 - 53,267,895 (+)	NCBI		UU_Cfam_GSD_1.0

Cers4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	212,706,004 - 212,713,170 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936588	5,107,663 - 5,131,140 (+)	Ensembl	SpeTri2.0
SpeTri2.0	NW_004936588	5,121,645 - 5,128,774 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CERS4
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	71,004,420 - 71,048,248 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	2	71,004,418 - 71,047,968 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	71,405,245 - 71,448,503 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

CERS4
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Vero_WHO_p1.0	NW_023666081	79,409 - 171,905 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Cers4
(Heterocephalus glaber - naked mole-rat)

Naked Mole-rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624828	1,074,942 - 1,092,647 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624828	1,074,920 - 1,092,607 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Cers4
244 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	504
Count of miRNA genes:	279
Interacting mature miRNAs:	326
Transcripts:	ENSRNOT00000001418
Prediction methods:	Microtar, Miranda
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1300174	Bw15	Body weight QTL 15	2.93		body mass (VT:0001259)	body weight loss (CMO:0001399)	12	1	9318387	Rat
2312418	Kidm41	Kidney mass QTL 41	3.7	0.0001	kidney mass (VT:0002707)	single kidney wet weight to body weight ratio (CMO:0000622)	12	1	19611090	Rat
10755457	Coatc14	Coat color QTL 14		0.01759	coat/hair pigmentation trait (VT:0010463)	pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)	12	1	22591684	Rat
6893681	Bw109	Body weight QTL 109	2.3	0.004	body mass (VT:0001259)	body weight (CMO:0000012)	12	1	23297788	Rat
1581516	Cm56	Cardiac mass QTL 56	4.2	0.05	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	12	1	29333307	Rat
1598855	Bp294	Blood pressure QTL 294	3.5		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	12	1	34851688	Rat
7411660	Foco28	Food consumption QTL 28	10.9	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	1	42110980	Rat
9590086	Insglur6	Insulin/glucose ratio QTL 6	18.97	0.001	blood insulin amount (VT:0001560)	calculated plasma insulin level (CMO:0002170)	12	1	42110980	Rat
8694179	Bw150	Body weight QTL 150	2.9	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	12	1	42110980	Rat
7411586	Foco5	Food consumption QTL 5	5.4	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	1	42110980	Rat
7411595	Foco9	Food consumption QTL 9	4	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	1	42110980	Rat
7411545	Bw128	Body weight QTL 128	5.2	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	12	1	42110980	Rat
9590147	Scort7	Serum corticosterone level QTL 7	13.61	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	12	1	42110980	Rat
2303575	Insul14	Insulin level QTL 14	4		blood insulin amount (VT:0001560)	blood insulin level (CMO:0000349)	12	1	42450532	Rat
737979	Pia22	Pristane induced arthritis QTL 22	53.1		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	12	1	44465750	Rat
634351	Apr5	Acute phase response QTL 5	6.7		blood interleukin-6 amount (VT:0008595)	plasma interleukin-6 level (CMO:0001927)	12	1	44503507	Rat
2302042	Pia38	Pristane induced arthritis QTL 38	3.5	0.001	blood immunoglobulin amount (VT:0002460)	serum immunoglobulin G1 level (CMO:0002115)	12	1	44503507	Rat
7243862	Mcs30	Mammary carcinoma susceptibility QTL 30	8.62		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	12	797729	8525593	Rat
634350	Apr4	Acute phase response QTL 4	6		orosomucoid 1 amount (VT:0010541)	plasma orosomucoid 1 level (CMO:0001467)	12	1172005	46172005	Rat

Markers in Region

RH133755

Rat Assembly	Chr	Position (strand)	Source	JBrowse
RH 3.4 Map	12	0.0	UniSTS
Cytogenetic Map	12	p12	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	3	40	15	4	16	4			74	27	34	11
Low		3	42	37	3	37	8	11		8	6		8
Below cutoff											1

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001107117	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006248804	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006248805	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039089315	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039089316	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039089317	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH474084	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000223	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000001418 ⟹ ENSRNOP00000001418

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	12	2,851,784 - 2,886,828 (+)	Ensembl
Rnor_6.0 Ensembl	12	4,439,750 - 4,474,729 (-)	Ensembl

RefSeq Acc Id:

NM_001107117 ⟹ NP_001100587

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	12	2,851,784 - 2,886,828 (+)	NCBI
Rnor_6.0	12	4,439,750 - 4,474,729 (-)	NCBI
Rnor_5.0	12	6,568,235 - 6,602,867 (-)	NCBI
RGSC_v3.4	12	1,256,396 - 1,291,578 (-)	RGD
Celera	12	4,665,718 - 4,700,469 (+)	RGD

Sequence:

show sequence

AGGCCTTGGCAGTCAAAGGAAGAGGCTGAAAGCAGGGATTGGGTCCCATTTCCTCTCTCGCGGG
TGGAGGCTTAGTAGAGAGGAGTTTCTCGGCCCAACGCGGTCTGTGGCGTGTCTACGGTGTCTTC
GGGTTAGCTGGTCCCCGCACCGCGTCGGCCTGCATCCTGCTGTCTGCACCCCCAGCATGCTGTT
CAGCTTGAATGAGTGGCTGTGGCAGGAGACATACTGGTTACCACCCAATGTCACATGGGCACAG
CTGGAGGACCGTGATGGCCTGGTGTTCGCCCACCCTCACCACGTGCTTGCTGCCTTGCCAATTG
CACTGGTCCTGGTGGCTATGCGTATCATCTTTGAGAGATTCGTGGCCTTGCCCCTGAGCCGGTG
GATGGGTGTGCAGGATCCAATCAGGAGAAAGATAAAGCCCAACCCAGTGCTGGAGAAATACTTC
CTCAGGATGAAGCAGAGACCAGTGGAGACCCAGATGGTCCTCCTGGCTTCCCAGTGTGGCCTCA
CGTTGCGGCAGATTCAACGCTGGTTCAGGAGACGTCGGAACCAGGATCGGCCTTGCCTGTCCAA
GAAATTCTGTGAAGCCAGCTGGAGGTTTGTCTTCTATCTGTGTTCCTTCGTGGGTGGCACCTCT
ATCCTCTACCATGAGTCATGGTTGTGGACACCGGCATTGTGCTGGGAGAATTACCCACATCAGA
CCCTGAATTTGGCCCTGTCCTGGTGGTACCTCCTGGAGCTGGGCTTCTACATTTCACTGCTAAT
CACTCTGCCCTTTGACATCAAACGCAAGGACTTCAAGGAGCAGGTGGCGCACCACTTCGTGACC
GTGGGACTGATCGTCTTCTCCTACAGCGTCAACCTCCTCCGCATTGGCTCTGTGGTACTGTTGT
TGCATGACTGCTCCGACTACCTGCTGGAGGGCTGTAAGATGCTCAACTATGCCCACTTTCAGCG
AGGGTGCGATACTCTTTTCATCATCTTCTCCTTAGTCTTCTTCTACACACGCCTCGTATTCTTC
CCCACCGAGGTCATCTACACTGCTGTGTTTGACTCAATCAAGAACTCAGGCCCCTTCTTTGGCT
ACTACTTCTTTATTGTGCTCCTGGGGATGCTACAGATTCTTCATGTGTACTGGTTCTGCCTCAT
CCTGCGCATGATCTGCAGTTTCCTGAGGAAGGGTCAGATGAGAGAGGACATTCGTAGTGATGTG
GAAGAATCAGACTCCAGTGATGACGAGGCAGTTTCTGAAGGTCCCCAGCTGAAGAATGGGATGG
CTCGAGGGTCTAGAGCAGCCATTACCAATGGCCCGCGGAGCCGGGCAGCAGCTTGCCTGACCAA
TGGGCACACCCGGGCCACATAGACAACCGCAGATTGACGTTGAGGGGTTGCCTCCAGCATTGTG
GATATTTAGATGCTGGACTGGTAACTCTGGGAGACAGGGAGGCCCTACCTTAAAGTAGGAAGAA
GACTGGTGATCTGTTTCCCTTCTGTTCTTCTCACTTTATCCCTTTGAACAACTTGACAGAACCT
GGGGGAGCAGTGGACTCTGCATCTGGCCAGAGCCACCCCCAGGCTATAGCTTGGGGGCTCTGGG
GAGCCTTGGCTCCAAGGACCAATAAAACTTCAACAGTGACGAATTCTCTGCCGCAAAGCTTGAG
TTCCCTTCACAGCTCTTCCTCTCCATTACTTACAGTGTTGACAAGATTCCTCACTGCCACATCA
GGATTTATGTCCACTCTTGCCGGTATAGCACCACAGCATGAAGATACTCCCTGCTCCTCAGTCA
GTGCCTTCAATTTGTTCTCCTTTAGAGTATCCCTCCAGGACATTAGCATTAGCCGATACAGGCT
GACTTTTAGGAAAGAGATTATTAAGCTTAGATGCAACCTCTCTCTCTGTCTGCAGTCCAAGCCA
GAGGGTAGAGCTGAAACCTGTGGATATCCTTGTAGTCCTTCGCTTAAAGCAACCTGCAGCCCAC
CCTGGGGTCTTTATACTCCCTTGGGATGGCGGAGAGCTAAGATTTGGTATGAGGTTACTGTCTT
CAGGAGTGCTATAGGAAAAGATCCTCCTCCAAGATTGGAGGGTGGGTGACCAGTGTTACTTAAC
TCAGAAATCAAAGCTAGAGGATCCATGTATGGTTAGACTGTGCCATCTTTGGGAGCAAGAGGAA
CCTTGTGTCGTGGGAGAAGGAAGAGAGTGGGGAGAAGAGGTCGTCTCAGGGGACTTCCAAAAAT
AAAGGCTCTTGGTACAAAGAGCAGAGCCTGGCATGGTGACCCATGGCTATCTTTAACATCAGAG
AGGAAGAATAGACTGGAAGAACATATGAACCTGGGATACAAAGCAGGGCCTGGTCTCAAAACAA
ACAACAGGTGGGCGTGTCAAGGAACAGGTACTCCAGAAGAGAAAACAATCGGAATCCGAGATAG
AAACAGCTAAGAAAAGGATGGGAAAAGAATGAGGGGTGACTCTGGGTGCAGAGCAGGTTGGTGA
GGTGAGATACGGAGTTTTGTCTTTTGGAGAAATATGGGGAAAAGGAAGAGAAATGTGGCTTCTG
TTGAGAGAACAACAGTAGGAGAAACAGAAGTAACACTGGTAGAGTATGCATAGGGACTTGTGAA
AGAGACAGGAAGACAAAGCAACTGATAGGGAAGGAAAGGGGGTTGGGAGGGATGAAGAAACAAC
AACAACACCAAAAAGAACAGAAAGAGGAAAATGGTGTTGATGGTGCATGGATGAGAAAACTGGA
AAAGATCGGGAAAGGGTATTTGAGAAGGAAGGCAGAGGGCCATTGACCAGAGTAACAGCTTCTA
GAGCACTTGAGGGATGGAAACAAGATGTGGCCACAAGTCTGAAATCACAGTACTCCTGATGCTG
AGGCAGAAAGATCCTAGGTTTGAGGCCAGCCTGGGAAGGAGTACCAACCTAAAAAAGCAACAAC
TGCAACAGGAAATGCGTGGAGGTATACATGGACACAATGGATTTCCGTTTTTCTTTTCTTTTTT
CTTTTTAGCTGTGAAGAATAAATCATGATAGTTGCAGAAAAATGGATGCAACTGGAAGCCATGT
TTGGTAGAGTAAAACAGTCAGACAAATACTGAATGTTTTTTATGCAAAAATTAGATTCAAATGA
TAAATGTTTGTGTATATGTGTTTTTTGCATTTGTATGTTTATAGGTCATGAAAATAGAGGGGTC
ATGGGTCAGGCATGGTGTTACACGCCTTTAATCCTAGCACTTGGGAGGCAGAGGCAGGCAGATC
TCTTGAGTTTGAGGCCAGCCTGGTCAACAAAGCAAATCCAGGACAGGGCTGTTACATAGAGAAA
CCCCATCTTGAAAA

hide sequence

RefSeq Acc Id:

XM_006248804 ⟹ XP_006248866

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	12	2,852,019 - 2,890,244 (+)	NCBI
Rnor_6.0	12	4,439,952 - 4,474,470 (-)	NCBI
Rnor_5.0	12	6,568,235 - 6,602,867 (-)	NCBI

Sequence:

show sequence

GTGGCGTGGGGGCGAGGCCAGGCCGCGGGTTGGGCAGTTTAGGGTTCAGGGGTCTTAGACTAAG
CGGTTCTTCGCGAGCACTGGGCCGGAGAGCACTGAAGCCACGCCCCTATCCCCTGCTCAGACCA
CGCCCAAGGCCCCATCAAACTCCTCCCGGAGGCCCCCTCCGGTCCCATTTCCTCTCTCGCGGGT
GGAGGCTTAGTAGAGAGGAGTTTCTCGGCCCAACGCGGTCTGTGGCGTGTCTACGGTGTCTTCG
GGTTAGCTGGTCCCCGCACCGCGTCGGCCTGCATCCTGCTGTCTGCACCCCCAGCATGCTGTTC
AGCTTGAATGAGTGGCTGTGGCAGGAGACATACTGGTTACCACCCAATGTCACATGGGCACAGC
TGGAGGACCGTGATGGCCTGGTGTTCGCCCACCCTCACCACGTGCTTGCTGCCTTGCCAATTGC
ACTGGTCCTGGTGGCTATGCGTATCATCTTTGAGAGATTCGTGGCCTTGCCCCTGAGCCGGTGG
ATGGGTGTGCAGGATCCAATCAGGAGAAAGATAAAGCCCAACCCAGTGCTGGAGAAATACTTCC
TCAGGATGAAGCAGAGACCAGTGGAGACCCAGATGGTCCTCCTGGCTTCCCAGTGTGGCCTCAC
GTTGCGGCAGATTCAACGCTGGTTCAGGAGACGTCGGAACCAGGATCGGCCTTGCCTGTCCAAG
AAATTCTGTGAAGCCAGCTGGAGGTTTGTCTTCTATCTGTGTTCCTTCGTGGGTGGCACCTCTA
TCCTCTACCATGAGTCATGGTTGTGGACACCGGCATTGTGCTGGGAGAATTACCCACATCAGAC
CCTGAATTTGGCCCTGTCCTGGTGGTACCTCCTGGAGCTGGGCTTCTACATTTCACTGCTAATC
ACTCTGCCCTTTGACATCAAACGCAAGGACTTCAAGGAGCAGGTGGCGCACCACTTCGTGACCG
TGGGACTGATCGTCTTCTCCTACAGCGTCAACCTCCTCCGCATTGGCTCTGTGGTACTGTTGTT
GCATGACTGCTCCGACTACCTGCTGGAGGGCTGTAAGATGCTCAACTATGCCCACTTTCAGCGA
GGGTGCGATACTCTTTTCATCATCTTCTCCTTAGTCTTCTTCTACACACGCCTCGTATTCTTCC
CCACCGAGGTCATCTACACTGCTGTGTTTGACTCAATCAAGAACTCAGGCCCCTTCTTTGGCTA
CTACTTCTTTATTGTGCTCCTGGGGATGCTACAGATTCTTCATGTGTACTGGTTCTGCCTCATC
CTGCGCATGATCTGCAGTTTCCTGAGGAAGGGTCAGATGAGAGAGGACATTCGTAGTGATGTGG
AAGAATCAGACTCCAGTGATGACGAGGCAGTTTCTGAAGGTCCCCAGCTGAAGAATGGGATGGC
TCGAGGGTCTAGAGCAGCCATTACCAATGGCCCGCGGAGCCGGGCAGCAGCTTGCCTGACCAAT
GGGCACACCCGGGCCACATAGACAACCGCAGATTGACGTTGAGGGGTTGCCTCCAGCATTGTGG
ATATTTAGATGCTGGACTGGTAACTCTGGGAGACAGGGAGGCCCTACCTTAAAGTAGGAAGAAG
ACTGGTGATCTGTTTCCCTTCTGTTCTTCTCACTTTATCCCTTTGAACAACTTGACAGAACCTG
GGGGAGCAGTGGACTCTGCATCTGGCCAGAGCCACCCCCAGGCTATAGCTTGGGGGCTCTGGGG
AGCCTTGGCTCCAAGGACCAATAAAACTTCAACAGTGACGAATTCTCTGCCGCAAAGCTTGAGT
TCCCTTCACAGCTCTTCCTCTCCATTACTTACAGTGTTGACAAGATTCCTCACTGCCACATCAG
GATTTATGTCCACTCTTGCCGGTATAGCACCACAGCATGAAGATACTCCCTGCTCCTCAGTCAG
TGCCTTCAATTTGTTCTCCTTTAGAGTATCCCTCCAGGACATTAGCATTAGCCGATACAGGCTG
ACTTTTAGGAAAGAGATTATTAAGCTTAGATGCAACCTCTCTCTCTGTCTGCAGTCCAAGCCAG
AGGGTAGAGCTGAAACCTGTGGATATCCTTGTAGTCCTTCGCTTAAAGCAACCTGCAGCCCACC
CTGGGGTCTTTATACTCCCTTGGGATGGCGGAGAGCTAAGATTTGGTATGAGGTTACTGTCTTC
AGGAGTGCTATAGGAAAAGATCCTCCTCCAAGATTGGAGGGTGGGTGACCAGTGTTACTTAACT
CAGAAATCAAAGCTAGAGGATCCATGTATGGTTAGACTGTGCCATCTTTGGGAGCAAGAGGAAC
CTTGTGTCGTGGGAGAAAGAGAAGAGAGTGGGGAGAAGAGGTCGTCTCAGGGGACTTCCAAAAA
TAAAGGCTCTTGGTACAAAGAGCAGAGCCTGGCATGGTGACCCATGGCTATCTTTAACATCAGA
GAGGAAGAATAGACTGGAAGAACATATGAACCTGGGATACAAAGCAGGGCCTGGTCTCAAAACA
AACAACAGGTGGGCGTGTCAAGGAACAGGTACTCCAGAAGAGAAAACAATCGGAATCCGAGATA
GAAACAGCTAAGAAAAGGATGGGAAAAGAATGAGGGGTGACTCTGGGTGCAGAGCAGGTTGGTG
AGGTGAGATACGGAGTTTTGTCTTTTGGAGAAATATGGGGAAAAGGAAGAGAAATGTGGCTTCT
GTTGAGAGAACAACAGTAGGAGAAACAGAAGTAACACTGGTAGAGTATGCATAGGGACTTGTGA
AAGAGACAGGAAGACAAAGCAACTGATAGGGAAGGAAAGGGGGTTGGGAGGGATGAAGAAACAA
CAACAACACCAAAAAGAACAGAAAGAGGAAAATGGTGTTGATGGTGCATGGATGAGAAAACTGG
AAAAGATCGGGAAAGGGTATTTGAGAAGGAAGGCAGAGGGCCATTGACCAGAGTAACAGCTTCT
AGAGAACTTGAGGGATGGAAACAAGATGTGGCCACAAGTCTGAAATCACAGTACTCCTGATGCT
GAGGCAGAAAGATCCTAGGTTTGAGGCCAGCCTGGGAAGGAGTACCAACCTAAAAAAGCAACAA
CTGCAACAGGAAATGCATGGAGGTATACATGGACACATGGATTTCTGTTTTTCTTTTTCTTTTC
TTTTTTCTTTTTAGCTGTGAAGAATAAATCATGATAGTTGCAGAAAAATGGATGCAACTGGAAG
CCATGTTTGGTAGAGTAAAACAGTCAGACAAATACTGAATGTTTTTTATGCAAAAATTAGATTC
AAATGATAAA

hide sequence

RefSeq Acc Id:

XM_039089315 ⟹ XP_038945243

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	12	2,852,008 - 2,890,244 (+)	NCBI

RefSeq Acc Id:

XM_039089316 ⟹ XP_038945244

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	12	2,852,008 - 2,890,244 (+)	NCBI

RefSeq Acc Id:

XM_039089317 ⟹ XP_038945245

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	12	2,852,008 - 2,890,244 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001100587	(Get FASTA)	NCBI Sequence Viewer
	XP_006248866	(Get FASTA)	NCBI Sequence Viewer
	XP_038945243	(Get FASTA)	NCBI Sequence Viewer
	XP_038945244	(Get FASTA)	NCBI Sequence Viewer
	XP_038945245	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL75005	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

NP_001100587 ⟸ NM_001107117

- UniProtKB:

D3ZU86 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MLFSLNEWLWQETYWLPPNVTWAQLEDRDGLVFAHPHHVLAALPIALVLVAMRIIFERFVALPL
SRWMGVQDPIRRKIKPNPVLEKYFLRMKQRPVETQMVLLASQCGLTLRQIQRWFRRRRNQDRPC
LSKKFCEASWRFVFYLCSFVGGTSILYHESWLWTPALCWENYPHQTLNLALSWWYLLELGFYIS
LLITLPFDIKRKDFKEQVAHHFVTVGLIVFSYSVNLLRIGSVVLLLHDCSDYLLEGCKMLNYAH
FQRGCDTLFIIFSLVFFYTRLVFFPTEVIYTAVFDSIKNSGPFFGYYFFIVLLGMLQILHVYWF
CLILRMICSFLRKGQMREDIRSDVEESDSSDDEAVSEGPQLKNGMARGSRAAITNGPRSRAAAC
LTNGHTRAT

hide sequence

RefSeq Acc Id:	XP_006248866 ⟸ XM_006248804
- Peptide Label:	isoform X1
- UniProtKB:	D3ZU86 (UniProtKB/TrEMBL)
- Sequence:	show sequence MLFSLNEWLWQETYWLPPNVTWAQLEDRDGLVFAHPHHVLAALPIALVLVAMRIIFERFVALPL SRWMGVQDPIRRKIKPNPVLEKYFLRMKQRPVETQMVLLASQCGLTLRQIQRWFRRRRNQDRPC LSKKFCEASWRFVFYLCSFVGGTSILYHESWLWTPALCWENYPHQTLNLALSWWYLLELGFYIS LLITLPFDIKRKDFKEQVAHHFVTVGLIVFSYSVNLLRIGSVVLLLHDCSDYLLEGCKMLNYAH FQRGCDTLFIIFSLVFFYTRLVFFPTEVIYTAVFDSIKNSGPFFGYYFFIVLLGMLQILHVYWF CLILRMICSFLRKGQMREDIRSDVEESDSSDDEAVSEGPQLKNGMARGSRAAITNGPRSRAAAC LTNGHTRAT hide sequence

RefSeq Acc Id:

ENSRNOP00000001418 ⟸ ENSRNOT00000001418

RefSeq Acc Id:	XP_038945244 ⟸ XM_039089316
- Peptide Label:	isoform X1
- UniProtKB:	D3ZU86 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038945243 ⟸ XM_039089315
- Peptide Label:	isoform X1
- UniProtKB:	D3ZU86 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038945245 ⟸ XM_039089317
- Peptide Label:	isoform X1
- UniProtKB:	D3ZU86 (UniProtKB/TrEMBL)

Protein Domains

Homeobox TLC

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3ZU86-F1-model_v2	AlphaFold	D3ZU86	1-393	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13698387

Promoter ID:

EPDNEW_R8911

Type:

multiple initiation site

Name:

Cers4_1

Description:

ceramide synthase 4

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	12	4,474,299 - 4,474,359	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1309303	AgrOrtholog
BioCyc Gene	G2FUF-20336	BioCyc
Ensembl Genes	ENSRNOG00000001072	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000001418	ENTREZGENE
	ENSRNOP00000001418.5	UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000001418	ENTREZGENE
	ENSRNOT00000001418.6	UniProtKB/TrEMBL
Gene3D-CATH	Homeodomain-like	UniProtKB/TrEMBL
InterPro	Homeobox	UniProtKB/TrEMBL
	Homeodomain-like	UniProtKB/TrEMBL
	Longevity_assurance_LAG1_LAC1	UniProtKB/TrEMBL
	TLC-dom	UniProtKB/TrEMBL
KEGG Report	rno:304208	UniProtKB/TrEMBL
NCBI Gene	304208	ENTREZGENE
PANTHER	CERAMIDE SYNTHASE 4	UniProtKB/TrEMBL
	PTHR12560	UniProtKB/TrEMBL
Pfam	Homeobox	UniProtKB/TrEMBL
	TRAM_LAG1_CLN8	UniProtKB/TrEMBL
PhenoGen	Cers4	PhenoGen
PIRSF	LAG1_LAC1	UniProtKB/TrEMBL
PROSITE	HOMEOBOX_2	UniProtKB/TrEMBL
	TLC	UniProtKB/TrEMBL
SMART	HOX	UniProtKB/TrEMBL
	TLC	UniProtKB/TrEMBL
Superfamily-SCOP	Homeodomain_like	UniProtKB/TrEMBL
UniProt	D3ZU86	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2011-08-02	Cers4	ceramide synthase 4	Lass4	LAG1 homolog, ceramide synthase 4	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-03-11	Lass4	LAG1 homolog, ceramide synthase 4	Lass4_predicted	longevity assurance homolog 4 (S. cerevisiae) (predicted)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-01-12	Lass4_predicted	longevity assurance homolog 4 (S. cerevisiae) (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar