Eif3b (eukaryotic translation initiation factor 3, subunit B) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Eif3b (eukaryotic translation initiation factor 3, subunit B) Rattus norvegicus
Analyze
Symbol: Eif3b
Name: eukaryotic translation initiation factor 3, subunit B
RGD ID: 1309018
Description: Predicted to enable RNA binding activity. Predicted to contribute to translation initiation factor activity. Predicted to be involved in several processes, including IRES-dependent viral translational initiation; translational initiation; and viral translational termination-reinitiation. Predicted to be located in cytoplasmic stress granule. Predicted to be part of eukaryotic translation initiation factor 3 complex, eIF3m. Predicted to be active in synapse. Orthologous to human EIF3B (eukaryotic translation initiation factor 3 subunit B); PARTICIPATES IN translation initiation pathway; RNA transport pathway; INTERACTS WITH (+)-schisandrin B; 2,4-dinitrotoluene; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: eIF-3-eta; Eif3s9; eukaryotic translation initiation factor 3 subunit 9; eukaryotic translation initiation factor 3 subunit B; eukaryotic translation initiation factor 3, subunit 9 (eta); LOC288516; MGC112720
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81219,310,308 - 19,334,768 (-)NCBIGRCr8
mRatBN7.21214,196,403 - 14,220,865 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1214,196,403 - 14,220,886 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1215,005,307 - 15,029,761 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01215,628,804 - 15,653,258 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01214,655,518 - 14,679,974 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01216,285,730 - 16,310,190 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1216,285,733 - 16,310,190 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01218,278,834 - 18,303,294 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41214,666,974 - 14,692,130 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11214,647,578 - 14,722,030 (-)NCBI
Celera1215,956,056 - 15,980,516 (-)NCBICelera
Cytogenetic Map12q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(-)-demecolcine  (ISO)
(-)-epigallocatechin 3-gallate  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
2-methylcholine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-amino-2,6-dinitrotoluene  (EXP)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenic trichloride  (ISO)
benzatropine  (ISO)
benzene  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
C60 fullerene  (EXP)
cadmium dichloride  (EXP,ISO)
caffeine  (ISO)
calcitriol  (ISO)
cannabidiol  (ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chloropicrin  (ISO)
chromium(6+)  (ISO)
clofibric acid  (EXP)
cocaine  (EXP)
CU-O LINKAGE  (ISO)
Cuprizon  (ISO)
deoxynivalenol  (ISO)
Dibutyl phosphate  (ISO)
diclofenac  (ISO)
doxorubicin  (ISO)
elemental selenium  (ISO)
ethanol  (EXP,ISO)
ethyl methanesulfonate  (ISO)
fenthion  (ISO)
flutamide  (EXP)
folic acid  (ISO)
formaldehyde  (ISO)
FR900359  (ISO)
furan  (EXP)
genistein  (ISO)
gentamycin  (EXP)
glafenine  (EXP)
hydrogen peroxide  (ISO)
ivermectin  (ISO)
lead(0)  (ISO)
methidathion  (ISO)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
Monobutylphthalate  (ISO)
N-nitrosodiethylamine  (EXP)
nefazodone  (EXP)
nimesulide  (EXP)
paracetamol  (ISO)
paraquat  (EXP)
putrescine  (EXP)
quercetin  (ISO)
SB 431542  (ISO)
selenium atom  (ISO)
sodium arsenite  (ISO)
spermidine  (EXP)
sunitinib  (ISO)
temozolomide  (ISO)
tetrachloromethane  (EXP,ISO)
thapsigargin  (EXP)
theophylline  (ISO)
thioacetamide  (EXP)
thiophenes  (ISO)
thiram  (ISO)
titanium dioxide  (ISO)
trimellitic anhydride  (ISO)
valproic acid  (ISO)
vincristine  (ISO)
vitamin E  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. The scanning mechanism of eukaryotic translation initiation. Hinnebusch AG Annu Rev Biochem. 2014;83:779-812. doi: 10.1146/annurev-biochem-060713-035802. Epub 2014 Jan 29.
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. Synaptotagmin 11 interacts with components of the RNA-induced silencing complex RISC in clonal pancreatic beta-cells. Milochau A, etal., FEBS Lett. 2014 Jun 27;588(14):2217-22. doi: 10.1016/j.febslet.2014.05.031. Epub 2014 May 29.
6. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
7. GOA pipeline RGD automated data pipeline
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:8995410   PMID:9573242   PMID:12477932   PMID:15489334   PMID:16452087   PMID:16641100   PMID:17322308   PMID:17581632   PMID:18599441   PMID:20458337   PMID:21347434   PMID:24003236  
PMID:25002582   PMID:25849773   PMID:27462815   PMID:30053369  


Genomics

Comparative Map Data
Eif3b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81219,310,308 - 19,334,768 (-)NCBIGRCr8
mRatBN7.21214,196,403 - 14,220,865 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1214,196,403 - 14,220,886 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1215,005,307 - 15,029,761 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01215,628,804 - 15,653,258 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01214,655,518 - 14,679,974 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01216,285,730 - 16,310,190 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1216,285,733 - 16,310,190 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01218,278,834 - 18,303,294 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41214,666,974 - 14,692,130 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11214,647,578 - 14,722,030 (-)NCBI
Celera1215,956,056 - 15,980,516 (-)NCBICelera
Cytogenetic Map12q11NCBI
EIF3B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3872,354,086 - 2,380,745 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl72,354,086 - 2,380,745 (+)EnsemblGRCh38hg38GRCh38
GRCh3772,393,721 - 2,420,380 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3672,361,000 - 2,386,906 (+)NCBINCBI36Build 36hg18NCBI36
Build 3472,167,741 - 2,193,616NCBI
Celera72,363,928 - 2,389,774 (+)NCBICelera
Cytogenetic Map7p22.3NCBI
HuRef72,313,949 - 2,339,345 (+)NCBIHuRef
CHM1_172,394,083 - 2,419,909 (+)NCBICHM1_1
T2T-CHM13v2.072,467,574 - 2,494,152 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v272,442,541 - 2,468,274 (+)NCBI
Eif3b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395140,405,060 - 140,429,113 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5140,405,083 - 140,429,115 (+)EnsemblGRCm39 Ensembl
GRCm385140,419,305 - 140,443,358 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5140,419,328 - 140,443,360 (+)EnsemblGRCm38mm10GRCm38
MGSCv375140,895,259 - 140,919,312 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365140,671,779 - 140,695,832 (+)NCBIMGSCv36mm8
Celera5137,477,208 - 137,501,576 (+)NCBICelera
Cytogenetic Map5G2NCBI
cM Map578.97NCBI
Eif3b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546012,917,389 - 12,941,126 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495546012,918,349 - 12,941,150 (-)NCBIChiLan1.0ChiLan1.0
EIF3B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v267,316,023 - 7,342,717 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1755,640,803 - 55,668,632 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v072,619,460 - 2,646,182 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.172,718,582 - 2,743,944 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl72,718,582 - 2,742,695 (+)Ensemblpanpan1.1panPan2
EIF3B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1614,780,318 - 14,802,938 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl614,781,215 - 14,803,883 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha616,242,639 - 16,265,270 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0614,906,371 - 14,929,004 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl614,907,264 - 14,929,069 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1614,709,937 - 14,732,572 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0614,638,275 - 14,660,849 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0614,924,356 - 14,946,923 (-)NCBIUU_Cfam_GSD_1.0
Eif3b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344142,929,948 - 142,953,382 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493682398,056 - 121,482 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493682398,056 - 121,489 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EIF3B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl31,645,706 - 1,666,091 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.131,645,462 - 1,666,096 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
EIF3B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12819,220,649 - 19,247,134 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2819,222,328 - 19,245,969 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660902,498,569 - 2,524,978 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Eif3b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474030,559,940 - 30,583,862 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474030,561,240 - 30,583,213 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Eif3b
85 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:64
Count of miRNA genes:53
Interacting mature miRNAs:54
Transcripts:ENSRNOT00000060444
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2312418Kidm41Kidney mass QTL 413.70.0001kidney mass (VT:0002707)single kidney wet weight to body weight ratio (CMO:0000622)12119611090Rat
8552964Pigfal17Plasma insulin-like growth factor 1 level QTL 173.5blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449546669029Rat
7411641Foco19Food consumption QTL 1927.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12556449546669029Rat
2302060Pia37Pristane induced arthritis QTL 376.10.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)121319815746669029Rat
1549912Bp268Blood pressure QTL 268arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)101318273646669029Rat
1641928Alcrsp5Alcohol response QTL 5response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)121281238546669029Rat
9590147Scort7Serum corticosterone level QTL 713.610.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)12142110980Rat
1549829Scl48Serum cholesterol level QTL 485blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)12960327746669029Rat
8552912Pigfal6Plasma insulin-like growth factor 1 level QTL 65blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449846669029Rat
61331Eau2Experimental allergic uveoretinitis QTL 20.0005uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)12852542328064601Rat
10059594Kidm46Kidney mass QTL 463.790.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)12610757946669029Rat
1581516Cm56Cardiac mass QTL 564.20.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)12129333307Rat
8552918Pigfal7Plasma insulin-like growth factor 1 level QTL 7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449546669029Rat
9590086Insglur6Insulin/glucose ratio QTL 618.970.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)12142110980Rat
6893681Bw109Body weight QTL 1092.30.004body mass (VT:0001259)body weight (CMO:0000012)12123297788Rat
1549902Bp269Blood pressure QTL 269arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)121318273646669029Rat
1302792Scl21Serum cholesterol level QTL 213.80.0011blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)12719673046669029Rat
61404Bw120Body weight QTL 1205.1body mass (VT:0001259)body mass index (BMI) (CMO:0000105)121235161946669029Rat
1331786Kidm11Kidney mass QTL 113.571kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)121107382524234895Rat
1598855Bp294Blood pressure QTL 2943.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)12134851688Rat
1600391Edcs2Endometrial carcinoma susceptibility QTL23.50.01uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)12683319017870186Rat
2293699Bss49Bone structure and strength QTL 495.610.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra trabecular cross-sectional area (CMO:0001692)121047413746669029Rat
1331761Bp218Blood pressure QTL 2182.973arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)121107382545055165Rat
10755457Coatc14Coat color QTL 140.01759coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)12122591684Rat
634351Apr5Acute phase response QTL 56.7blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)12144503507Rat
634350Apr4Acute phase response QTL 46orosomucoid 1 amount (VT:0010541)plasma orosomucoid 1 level (CMO:0001467)12117200546172005Rat
8694179Bw150Body weight QTL 1502.90.001body mass (VT:0001259)body weight gain (CMO:0000420)12142110980Rat
61416Pia4Pristane induced arthritis QTL 48.4joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)121363552330827399Rat
7411545Bw128Body weight QTL 1285.20.001body mass (VT:0001259)body weight gain (CMO:0000420)12142110980Rat
7204484Bp358Blood pressure QTL 3580.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)121300829619212979Rat
7411547Bw129Body weight QTL 1290.001body mass (VT:0001259)body weight gain (CMO:0000420)6556449546669029Rat
7387292Kidm42Kidney mass QTL 423.030.0004kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)12136247923Rat
61421Cia12Collagen induced arthritis QTL 124.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)121363552335682913Rat
1300157Rf21Renal function QTL 214.4renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)12931821632103380Rat
737979Pia22Pristane induced arthritis QTL 2253.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)12144465750Rat
2303569Gluco44Glucose level QTL 442blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)121281238546669029Rat
7411586Foco5Food consumption QTL 55.40.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12142110980Rat
2303575Insul14Insulin level QTL 144blood insulin amount (VT:0001560)blood insulin level (CMO:0000349)12142450532Rat
7411588Foco6Food consumption QTL 60.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12556449546669029Rat
2302042Pia38Pristane induced arthritis QTL 383.50.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)12144503507Rat
2300186Bmd59Bone mineral density QTL 597.10.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)121047413746669029Rat
7411595Foco9Food consumption QTL 940.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12142110980Rat
2293086Iddm30Insulin dependent diabetes mellitus QTL 303.82blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)12844949028302290Rat
7411597Foco10Food consumption QTL 100.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12556449546669029Rat
7411660Foco28Food consumption QTL 2810.90.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12142110980Rat
1331755Bp219Blood pressure QTL 2193.041arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)121107382528064557Rat

Markers in Region
RH128231  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21214,196,496 - 14,196,693 (+)MAPPERmRatBN7.2
Rnor_6.01216,285,824 - 16,286,020NCBIRnor6.0
Rnor_5.01218,278,928 - 18,279,124UniSTSRnor5.0
RGSC_v3.41214,667,068 - 14,667,264UniSTSRGSC3.4
Celera1215,956,150 - 15,956,346UniSTS
RH 3.4 Map12236.0UniSTS
Cytogenetic Map12q11UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000060444   ⟹   ENSRNOP00000057188
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1214,196,403 - 14,220,886 (-)Ensembl
Rnor_6.0 Ensembl1216,285,733 - 16,310,190 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000099724   ⟹   ENSRNOP00000097491
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1214,196,403 - 14,220,886 (-)Ensembl
RefSeq Acc Id: NM_001031640   ⟹   NP_001026810
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81219,310,308 - 19,334,768 (-)NCBI
mRatBN7.21214,196,403 - 14,220,865 (-)NCBI
Rnor_6.01216,285,730 - 16,310,190 (-)NCBI
Rnor_5.01218,278,834 - 18,303,294 (-)NCBI
RGSC_v3.41214,666,974 - 14,692,130 (-)RGD
Celera1215,956,056 - 15,980,516 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001026810 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH98728 (Get FASTA)   NCBI Sequence Viewer  
  EDL89734 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000057188.1
  ENSRNOP00000097491.1
  ENSRNOP00055016021
  ENSRNOP00060042534
  ENSRNOP00065000230
GenBank Protein Q4G061 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001026810   ⟸   NM_001031640
- UniProtKB: Q4G061 (UniProtKB/Swiss-Prot),   A6K1S6 (UniProtKB/TrEMBL),   A0A8I6B5U9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000057188   ⟸   ENSRNOT00000060444
Ensembl Acc Id: ENSRNOP00000097491   ⟸   ENSRNOT00000099724
Protein Domains
RRM

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q4G061-F1-model_v2 AlphaFold Q4G061 1-797 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698455
Promoter ID:EPDNEW_R8980
Type:multiple initiation site
Name:Eif3b_1
Description:eukaryotic translation initiation factor 3, subunit B
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01216,310,209 - 16,310,269EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309018 AgrOrtholog
BioCyc Gene G2FUF-19920 BioCyc
Ensembl Genes ENSRNOG00000001253 Ensembl, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOG00055011690 UniProtKB/Swiss-Prot
  ENSRNOG00060029458 UniProtKB/Swiss-Prot
  ENSRNOG00065000134 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000060444.2 UniProtKB/Swiss-Prot
  ENSRNOT00000099724.1 UniProtKB/TrEMBL
  ENSRNOT00055019857 UniProtKB/Swiss-Prot
  ENSRNOT00060051124 UniProtKB/Swiss-Prot
  ENSRNOT00065000231 UniProtKB/Swiss-Prot
Gene3D-CATH 2.130.10.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.30.70.330 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7381504 IMAGE-MGC_LOAD
InterPro EIF3B UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  eIF3B_RRM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Nucleotide-bd_a/b_plait_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RBD_domain_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RRM_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TIF_beta_prop-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:288516 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:112720 IMAGE-MGC_LOAD
NCBI Gene 288516 ENTREZGENE
PANTHER EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT B UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR14068 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam eIF2A UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RRM_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Eif3b PhenoGen
PIRSF eIF3b UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE RRM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000001253 RatGTEx
  ENSRNOG00055011690 RatGTEx
  ENSRNOG00060029458 RatGTEx
  ENSRNOG00065000134 RatGTEx
SMART RRM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP DPP6 N-terminal domain-like UniProtKB/TrEMBL
  SSF54928 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tricorn protease domain 2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I6B5U9 ENTREZGENE, UniProtKB/TrEMBL
  A6K1S6 ENTREZGENE, UniProtKB/TrEMBL
  EIF3B_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2010-04-20 Eif3b  eukaryotic translation initiation factor 3, subunit B  Eif3s9  eukaryotic translation initiation factor 3, subunit 9 (eta)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Eif3s9  eukaryotic translation initiation factor 3, subunit 9 (eta)  Eif3s9_predicted  eukaryotic translation initiation factor 3, subunit 9 (eta) (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Eif3s9_predicted  eukaryotic translation initiation factor 3, subunit 9 (eta) (predicted)      Symbol and Name status set to approved 70820 APPROVED