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Gene: Psph (phosphoserine phosphatase) Rattus norvegicus
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Symbol: Psph
Name: phosphoserine phosphatase
Description: Predicted to have metal ion binding activity; phosphoserine phosphatase activity; and protein homodimerization activity. Involved in response to mechanical stimulus; response to nutrient levels; and response to testosterone. Localizes to the neuron projection. Human ortholog(s) of this gene implicated in PSPH deficiency. Orthologous to human PSPH (phosphoserine phosphatase); PARTICIPATES IN dihydropyrimidine dehydrogenase deficiency pathway; dimethylglycine dehydrogenase deficiency pathway; nonketotic hyperglycinemia pathway; INTERACTS WITH 17alpha-ethynylestradiol; 3-chloropropane-1,2-diol; all-trans-retinoic acid.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC304429; MGC109524; O-phosphoserine phosphohydrolase; PSP; PSPase
Orthologs:
Homo sapiens (human) : PSPH (phosphoserine phosphatase)  HGNC  Alliance
Mus musculus (house mouse) : Psph (phosphoserine phosphatase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Psph (phosphoserine phosphatase)
Pan paniscus (bonobo/pygmy chimpanzee) : PSPH (phosphoserine phosphatase)
Canis lupus familiaris (dog) : PSPH (phosphoserine phosphatase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Psph (phosphoserine phosphatase)
Sus scrofa (pig) : PSPH (phosphoserine phosphatase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01230,514,128 - 30,526,551 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01232,455,767 - 32,468,319 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41227,969,748 - 27,984,318 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11227,833,136 - 27,847,706 (-)NCBI
Celera1228,596,700 - 28,610,791 (+)NCBICelera
Cytogenetic Map12q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Psph
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1308764
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.