Bhlha15 (basic helix-loop-helix family, member a15) - Rat Genome Database

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Gene: Bhlha15 (basic helix-loop-helix family, member a15) Rattus norvegicus
Analyze
Symbol: Bhlha15
Name: basic helix-loop-helix family, member a15
RGD ID: 3091
Description: Enables DNA binding activity. Predicted to be involved in several processes, including cellular response to glucose starvation; negative regulation of myotube differentiation; and neuron differentiation. Predicted to act upstream of or within several processes, including cell-cell adhesion mediated by cadherin; intracellular distribution of mitochondria; and type B pancreatic cell maturation. Located in nucleus. Orthologous to human BHLHA15 (basic helix-loop-helix family member a15); PARTICIPATES IN maturity-onset diabetes of the young pathway; INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: basic helix-loop-helix domain containing, class B, 8; basic helix-loop-helix transcription factor (bHlH); bHlH; Bhlhb8; class A basic helix-loop-helix protein 15; class B basic helix-loop-helix protein 8; MIST-1; Mist1; muscle, intestine and stomach expression 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21210,420,465 - 10,424,641 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1210,420,467 - 10,424,713 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1211,227,709 - 11,231,885 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01211,851,005 - 11,855,181 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01210,874,437 - 10,878,619 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01212,403,385 - 12,409,103 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1212,403,385 - 12,407,561 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01214,455,040 - 14,459,246 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41210,747,865 - 10,752,041 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11210,777,792 - 10,781,969 (-)NCBI
Celera1212,219,590 - 12,223,766 (-)NCBICelera
Cytogenetic Map12p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleus  (IBA,IDA,IEA,ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. A tripartite protein complex with the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. Butz S, etal., Cell 1998 Sep 18;94(6):773-82.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Mist1: a novel basic helix-loop-helix transcription factor exhibits a developmentally regulated expression pattern. Lemercier C, etal., Dev Biol 1997 Feb 1;182(1):101-13.
4. The rat Mist1 gene: structure and promoter characterization. Lemercier C, etal., Gene 2000 Jan 25;242(1-2):209-18.
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
7. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
8. GOA pipeline RGD automated data pipeline
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
11. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
Additional References at PubMed
PMID:11696558   PMID:12829745   PMID:12921743   PMID:15024058   PMID:15112319   PMID:15489334   PMID:15665001   PMID:16423820   PMID:17605298   PMID:17612490  


Genomics

Comparative Map Data
Bhlha15
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21210,420,465 - 10,424,641 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1210,420,467 - 10,424,713 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1211,227,709 - 11,231,885 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01211,851,005 - 11,855,181 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01210,874,437 - 10,878,619 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01212,403,385 - 12,409,103 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1212,403,385 - 12,407,561 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01214,455,040 - 14,459,246 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41210,747,865 - 10,752,041 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11210,777,792 - 10,781,969 (-)NCBI
Celera1212,219,590 - 12,223,766 (-)NCBICelera
Cytogenetic Map12p11NCBI
BHLHA15
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38798,211,439 - 98,215,457 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl798,211,439 - 98,215,457 (+)EnsemblGRCh38hg38GRCh38
GRCh37797,840,751 - 97,844,769 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36797,679,502 - 97,680,207 (+)NCBINCBI36Build 36hg18NCBI36
Build 34797,486,254 - 97,486,842NCBI
Celera792,535,465 - 92,536,170 (+)NCBICelera
Cytogenetic Map7q21.3NCBI
HuRef792,442,435 - 92,443,140 (+)NCBIHuRef
CHM1_1797,771,610 - 97,772,315 (+)NCBICHM1_1
T2T-CHM13v2.0799,441,577 - 99,445,595 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2797,166,444 - 97,167,149 (+)NCBI
Bhlha15
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395144,127,104 - 144,131,259 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5144,127,104 - 144,131,259 (+)EnsemblGRCm39 Ensembl
GRCm385144,190,286 - 144,194,441 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5144,190,286 - 144,194,441 (+)EnsemblGRCm38mm10GRCm38
MGSCv375144,951,155 - 144,955,310 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365144,443,813 - 144,447,968 (+)NCBIMGSCv36mm8
Celera5141,174,663 - 141,178,820 (+)NCBICelera
Cytogenetic Map5G2NCBI
cM Map583.05NCBI
Bhlha15
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546014,103,053 - 14,106,714 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495546014,103,053 - 14,106,714 (+)NCBIChiLan1.0ChiLan1.0
BHLHA15
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan17164,322,479 - 164,326,423 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v076,306,929 - 6,311,026 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17103,676,211 - 103,680,153 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7103,677,022 - 103,677,593 (+)Ensemblpanpan1.1panPan2
BHLHA15
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1611,112,233 - 11,115,776 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl611,114,694 - 11,115,257 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha612,738,597 - 12,742,381 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0611,112,675 - 11,116,461 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1610,981,367 - 10,985,151 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0610,961,184 - 10,964,967 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0611,195,228 - 11,199,013 (-)NCBIUU_Cfam_GSD_1.0
Bhlha15
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344139,188,655 - 139,192,549 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936750753,615 - 754,187 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936750752,887 - 756,562 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BHLHA15
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl35,410,518 - 5,414,072 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.135,410,467 - 5,414,074 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.235,464,958 - 5,473,366 (+)NCBISscrofa10.2Sscrofa10.2susScr3
BHLHA15
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12814,953,483 - 14,957,674 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2814,956,095 - 14,956,679 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660701,119,815 - 1,123,886 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Bhlha15
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474031,672,397 - 31,674,205 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474031,671,820 - 31,676,045 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Bhlha15
11 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:414
Count of miRNA genes:226
Interacting mature miRNAs:283
Transcripts:ENSRNOT00000037251
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2312418Kidm41Kidney mass QTL 413.70.0001kidney mass (VT:0002707)single kidney wet weight to body weight ratio (CMO:0000622)12119611090Rat
10755457Coatc14Coat color QTL 140.01759coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)12122591684Rat
6893681Bw109Body weight QTL 1092.30.004body mass (VT:0001259)body weight (CMO:0000012)12123297788Rat
1581516Cm56Cardiac mass QTL 564.20.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)12129333307Rat
1598855Bp294Blood pressure QTL 2943.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)12134851688Rat
7411660Foco28Food consumption QTL 2810.90.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12142110980Rat
9590086Insglur6Insulin/glucose ratio QTL 618.970.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)12142110980Rat
8694179Bw150Body weight QTL 1502.90.001body mass (VT:0001259)body weight gain (CMO:0000420)12142110980Rat
7411586Foco5Food consumption QTL 55.40.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12142110980Rat
7411595Foco9Food consumption QTL 940.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12142110980Rat
7411545Bw128Body weight QTL 1285.20.001body mass (VT:0001259)body weight gain (CMO:0000420)12142110980Rat
9590147Scort7Serum corticosterone level QTL 713.610.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)12142110980Rat
2303575Insul14Insulin level QTL 144blood insulin amount (VT:0001560)blood insulin level (CMO:0000349)12142450532Rat
737979Pia22Pristane induced arthritis QTL 2253.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)12144465750Rat
634351Apr5Acute phase response QTL 56.7blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)12144503507Rat
2302042Pia38Pristane induced arthritis QTL 383.50.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)12144503507Rat
634350Apr4Acute phase response QTL 46orosomucoid 1 amount (VT:0010541)plasma orosomucoid 1 level (CMO:0001467)12117200546172005Rat
8552918Pigfal7Plasma insulin-like growth factor 1 level QTL 7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449546669029Rat
7411547Bw129Body weight QTL 1290.001body mass (VT:0001259)body weight gain (CMO:0000420)6556449546669029Rat
7411597Foco10Food consumption QTL 100.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12556449546669029Rat
7411641Foco19Food consumption QTL 1927.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12556449546669029Rat
8552964Pigfal17Plasma insulin-like growth factor 1 level QTL 173.5blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449546669029Rat
7411588Foco6Food consumption QTL 60.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12556449546669029Rat
8552912Pigfal6Plasma insulin-like growth factor 1 level QTL 65blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449846669029Rat
10059594Kidm46Kidney mass QTL 463.790.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)12610757946669029Rat
1600391Edcs2Endometrial carcinoma susceptibility QTL23.50.01uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)12683319017870186Rat
1302792Scl21Serum cholesterol level QTL 213.80.0011blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)12719673046669029Rat
2293086Iddm30Insulin dependent diabetes mellitus QTL 303.82blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)12844949028302290Rat
61331Eau2Experimental allergic uveoretinitis QTL 20.0005uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)12852542328064601Rat
1331739Hrtrt14Heart rate QTL 143.56232heart pumping trait (VT:2000009)heart rate (CMO:0000002)12931821612829686Rat
1300157Rf21Renal function QTL 214.4renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)12931821632103380Rat
1549829Scl48Serum cholesterol level QTL 485blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)12960327746669029Rat

Markers in Region
D12Wox29  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21210,426,000 - 10,426,267 (+)MAPPERmRatBN7.2
mRatBN7.21210,426,164 - 10,426,267 (+)MAPPERmRatBN7.2
Rnor_6.01212,409,085 - 12,409,366NCBIRnor6.0
Rnor_6.01212,409,266 - 12,409,366NCBIRnor6.0
Rnor_5.01214,460,921 - 14,461,021UniSTSRnor5.0
Rnor_5.01214,460,740 - 14,461,021UniSTSRnor5.0
RGSC_v3.41210,753,565 - 10,753,665UniSTSRGSC3.4
Celera1212,225,290 - 12,225,388UniSTS
Cytogenetic Map12p11UniSTS
D12Wox19  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21210,423,273 - 10,423,429 (+)MAPPERmRatBN7.2
Rnor_6.01212,406,194 - 12,406,349NCBIRnor6.0
Rnor_5.01214,457,849 - 14,458,004UniSTSRnor5.0
RGSC_v3.41210,750,674 - 10,750,829UniSTSRGSC3.4
Celera1212,222,399 - 12,222,554UniSTS
Cytogenetic Map12p11UniSTS
D12Wox20  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21210,422,381 - 10,422,669 (+)MAPPERmRatBN7.2
Rnor_6.01212,405,302 - 12,405,589NCBIRnor6.0
Rnor_5.01214,456,957 - 14,457,244UniSTSRnor5.0
RGSC_v3.41210,749,782 - 10,750,069UniSTSRGSC3.4
Celera1212,221,507 - 12,221,794UniSTS
Cytogenetic Map12p11UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 2 2
Low 3 55 39 19 39 38 17 15 11
Below cutoff 37 8 11 36 18 25 8

Sequence


RefSeq Acc Id: ENSRNOT00000037251   ⟹   ENSRNOP00000035219
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1210,420,467 - 10,424,713 (-)Ensembl
Rnor_6.0 Ensembl1212,403,385 - 12,407,561 (-)Ensembl
RefSeq Acc Id: NM_012863   ⟹   NP_036995
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21210,420,465 - 10,424,641 (-)NCBI
Rnor_6.01212,403,385 - 12,407,561 (-)NCBI
Rnor_5.01214,455,040 - 14,459,246 (-)NCBI
RGSC_v3.41210,747,865 - 10,752,041 (-)RGD
Celera1212,219,590 - 12,223,766 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_036995 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAC53111 (Get FASTA)   NCBI Sequence Viewer  
  AAF17707 (Get FASTA)   NCBI Sequence Viewer  
  AAH61868 (Get FASTA)   NCBI Sequence Viewer  
  EDL89638 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000035219.5
GenBank Protein P70562 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_036995   ⟸   NM_012863
- UniProtKB: P70562 (UniProtKB/Swiss-Prot),   A6K1I0 (UniProtKB/TrEMBL),   A0A8L2QJ40 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000035219   ⟸   ENSRNOT00000037251
Protein Domains
bHLH

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P70562-F1-model_v2 AlphaFold P70562 1-197 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698427
Promoter ID:EPDNEW_R8952
Type:initiation region
Name:Bhlha15_1
Description:basic helix-loop-helix family, member a15
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01212,407,519 - 12,407,579EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:3091 AgrOrtholog
BioCyc Gene G2FUF-20031 BioCyc
Ensembl Genes ENSRNOG00000025164 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000037251.6 UniProtKB/TrEMBL
Gene3D-CATH 4.10.280.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:5598799 IMAGE-MGC_LOAD
InterPro bHLH_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HLH_DNA-bd_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:25334 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:72528 IMAGE-MGC_LOAD
NCBI Gene 25334 ENTREZGENE
PANTHER BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CLASS A BASIC HELIX-LOOP-HELIX PROTEIN 15 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam HLH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Bhlha15 PhenoGen
PROSITE BHLH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000025164 RatGTEx
SMART HLH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF47459 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGR TC222251
UniProt A0A8L2QJ40 ENTREZGENE, UniProtKB/TrEMBL
  A6K1I0 ENTREZGENE, UniProtKB/TrEMBL
  BHA15_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2009-02-19 Bhlha15  basic helix-loop-helix family, member a15  Bhlhb8  basic helix-loop-helix domain containing, class B, 8  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Bhlhb8  basic helix-loop-helix domain containing, class B, 8  Mist1  muscle, intestine and stomach expression 1  Symbol and Name updated 1299863 APPROVED
2002-06-10 Mist1  Basic helix-loop-helix transcription factor (bHlH)      Symbol and Name status set to approved 70586 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_physical_interaction binds to the DNA target sequence -CANNTG- (E-box) 633179
gene_product member of basic helix-loop-helix transcription factor family 633179