Cdk8 (cyclin-dependent kinase 8) - Rat Genome Database

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Gene: Cdk8 (cyclin-dependent kinase 8) Rattus norvegicus
Analyze
Symbol: Cdk8 (Ensembl: AABR07035338.1)
Name: cyclin-dependent kinase 8
RGD ID: 1560888
Description: Contributes to ubiquitin protein ligase activity. Involved in negative regulation of triglyceride metabolic process and protein ubiquitination. Part of ubiquitin ligase complex. Human ortholog(s) of this gene implicated in dilated cardiomyopathy. Orthologous to human CDK8 (cyclin dependent kinase 8); PARTICIPATES IN RNA polymerase II transcription pathway; INTERACTS WITH (+)-schisandrin B; bisphenol A; flutamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC498140; RGD1560888; similar to Cell division protein kinase 8 (Protein kinase K35)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81213,851,024 - 13,919,017 (-)NCBIGRCr8
mRatBN7.2128,737,198 - 8,805,026 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl128,737,262 - 8,804,177 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx129,534,947 - 9,601,599 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01210,158,140 - 10,224,798 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0129,181,585 - 9,248,239 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01210,496,273 - 10,561,335 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01212,597,402 - 12,663,842 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4129,215,964 - 9,254,015 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1210,565,691 - 10,631,673 (-)NCBICelera
Cytogenetic Map12p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Mammalian mediator subunit mMED8 is an Elongin BC-interacting protein that can assemble with Cul2 and Rbx1 to reconstitute a ubiquitin ligase. Brower CS, etal., Proc Natl Acad Sci U S A. 2002 Aug 6;99(16):10353-8. Epub 2002 Jul 29.
2. Updating the RNA polymerase CTD code: adding gene-specific layers. Egloff S, etal., Trends Genet. 2012 Jul;28(7):333-41. doi: 10.1016/j.tig.2012.03.007. Epub 2012 May 21.
3. The writers, readers, and functions of the RNA polymerase II C-terminal domain code. Jeronimo C, etal., Chem Rev. 2013 Nov 13;113(11):8491-522. doi: 10.1021/cr4001397. Epub 2013 Jul 10.
4. The Mediator complex and transcription regulation. Poss ZC, etal., Crit Rev Biochem Mol Biol. 2013 Nov-Dec;48(6):575-608. doi: 10.3109/10409238.2013.840259. Epub 2013 Oct 3.
5. GOA pipeline RGD automated data pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Comprehensive gene review and curation RGD comprehensive gene curation
9. Association between CDK8 gene polymorphisms and dilated cardiomyopathy in a Chinese Han population. Zhang R, etal., Cardiovasc Diagn Ther. 2021 Oct;11(5):1036-1046. doi: 10.21037/cdt-21-323.
10. Regulation of lipogenesis by cyclin-dependent kinase 8-mediated control of SREBP-1. Zhao X, etal., J Clin Invest. 2012 Jul 2;122(7):2417-27. doi: 10.1172/JCI61462. Epub 2012 Jun 11.
Additional References at PubMed
PMID:14638676   PMID:15340084   PMID:16109376   PMID:22869755   PMID:33737500  


Genomics

Comparative Map Data
Cdk8
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81213,851,024 - 13,919,017 (-)NCBIGRCr8
mRatBN7.2128,737,198 - 8,805,026 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl128,737,262 - 8,804,177 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx129,534,947 - 9,601,599 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01210,158,140 - 10,224,798 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0129,181,585 - 9,248,239 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01210,496,273 - 10,561,335 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01212,597,402 - 12,663,842 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4129,215,964 - 9,254,015 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1210,565,691 - 10,631,673 (-)NCBICelera
Cytogenetic Map12p11NCBI
CDK8
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381326,254,129 - 26,405,238 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1326,254,104 - 26,420,982 (+)EnsemblGRCh38hg38GRCh38
GRCh371326,828,266 - 26,979,375 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361325,726,756 - 25,876,569 (+)NCBINCBI36Build 36hg18NCBI36
Build 341325,726,755 - 25,876,569NCBI
Celera137,896,857 - 8,046,682 (+)NCBICelera
Cytogenetic Map13q12.13NCBI
HuRef137,646,374 - 7,796,038 (+)NCBIHuRef
CHM1_11326,796,796 - 26,946,621 (+)NCBICHM1_1
T2T-CHM13v2.01325,467,904 - 25,619,002 (+)NCBIT2T-CHM13v2.0
Cdk8
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395146,167,432 - 146,239,684 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5146,168,040 - 146,239,684 (+)EnsemblGRCm39 Ensembl
GRCm385146,230,795 - 146,302,874 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5146,231,230 - 146,302,874 (+)EnsemblGRCm38mm10GRCm38
MGSCv375147,043,251 - 147,114,450 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365146,535,913 - 146,607,053 (+)NCBIMGSCv36mm8
Celera5144,210,649 - 144,281,842 (+)NCBICelera
Cytogenetic Map5G3NCBI
cM Map585.19NCBI
Cdk8
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554975,781,237 - 5,908,374 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554975,781,237 - 5,908,072 (+)NCBIChiLan1.0ChiLan1.0
CDK8
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21425,853,105 - 26,004,531 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11316,962,029 - 17,112,677 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0137,546,922 - 7,698,079 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11325,895,353 - 26,046,120 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1325,895,705 - 26,046,120 (+)Ensemblpanpan1.1panPan2
CDK8
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12513,043,949 - 13,179,752 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2513,045,343 - 13,179,656 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2513,114,192 - 13,250,035 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02513,179,325 - 13,315,182 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2513,180,701 - 13,315,567 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12513,063,086 - 13,198,906 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02513,055,645 - 13,191,566 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02513,106,469 - 13,242,317 (-)NCBIUU_Cfam_GSD_1.0
Cdk8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945114,926,309 - 115,028,565 (+)NCBIHiC_Itri_2
SpeTri2.0NW_00493694891,578 - 236,051 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CDK8
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl114,054,442 - 4,161,481 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1114,054,442 - 4,161,501 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2113,493,422 - 3,545,124 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CDK8
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.135,505,532 - 5,652,527 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl35,505,625 - 5,651,366 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605738,774,603 - 38,922,173 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cdk8
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477612,157,892 - 12,325,081 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477612,114,277 - 12,324,481 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Cdk8
349 total Variants

QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300174Bw15Body weight QTL 152.93body mass (VT:0001259)body weight loss (CMO:0001399)1219318387Rat
2312418Kidm41Kidney mass QTL 413.70.0001kidney mass (VT:0002707)single kidney wet weight to body weight ratio (CMO:0000622)12119611090Rat
10755457Coatc14Coat color QTL 140.01759coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)12122591684Rat
6893681Bw109Body weight QTL 1092.30.004body mass (VT:0001259)body weight (CMO:0000012)12123297788Rat
1581516Cm56Cardiac mass QTL 564.20.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)12129333307Rat
1598855Bp294Blood pressure QTL 2943.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)12134851688Rat
7411660Foco28Food consumption QTL 2810.90.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12142110980Rat
9590086Insglur6Insulin/glucose ratio QTL 618.970.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)12142110980Rat
8694179Bw150Body weight QTL 1502.90.001body mass (VT:0001259)body weight gain (CMO:0000420)12142110980Rat
7411586Foco5Food consumption QTL 55.40.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12142110980Rat
7411595Foco9Food consumption QTL 940.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12142110980Rat
7411545Bw128Body weight QTL 1285.20.001body mass (VT:0001259)body weight gain (CMO:0000420)12142110980Rat
9590147Scort7Serum corticosterone level QTL 713.610.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)12142110980Rat
2303575Insul14Insulin level QTL 144blood insulin amount (VT:0001560)blood insulin level (CMO:0000349)12142450532Rat
737979Pia22Pristane induced arthritis QTL 2253.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)12144465750Rat
634351Apr5Acute phase response QTL 56.7blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)12144503507Rat
2302042Pia38Pristane induced arthritis QTL 383.50.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)12144503507Rat
634350Apr4Acute phase response QTL 46orosomucoid 1 amount (VT:0010541)plasma orosomucoid 1 level (CMO:0001467)12117200546172005Rat
724526Uae3Urinary albumin excretion QTL 34.90.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)12390696910373166Rat
8552918Pigfal7Plasma insulin-like growth factor 1 level QTL 7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449546669029Rat
7411547Bw129Body weight QTL 1290.001body mass (VT:0001259)body weight gain (CMO:0000420)6556449546669029Rat
7411597Foco10Food consumption QTL 100.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12556449546669029Rat
7411641Foco19Food consumption QTL 1927.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12556449546669029Rat
8552964Pigfal17Plasma insulin-like growth factor 1 level QTL 173.5blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449546669029Rat
7411588Foco6Food consumption QTL 60.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12556449546669029Rat
8552912Pigfal6Plasma insulin-like growth factor 1 level QTL 65blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449846669029Rat
10059594Kidm46Kidney mass QTL 463.790.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)12610757946669029Rat
1600391Edcs2Endometrial carcinoma susceptibility QTL23.50.01uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)12683319017870186Rat
1302792Scl21Serum cholesterol level QTL 213.80.0011blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)12719673046669029Rat
2293086Iddm30Insulin dependent diabetes mellitus QTL 303.82blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)12844949028302290Rat
61331Eau2Experimental allergic uveoretinitis QTL 20.0005uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)12852542328064601Rat

Markers in Region
BM389681  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2128,744,456 - 8,744,646 (+)MAPPERmRatBN7.2
Rnor_6.01210,503,468 - 10,503,657NCBIRnor6.0
Rnor_5.01212,604,597 - 12,604,786UniSTSRnor5.0
Celera1210,572,917 - 10,573,106UniSTS
RH 3.4 Map12108.9UniSTS
Cytogenetic Map12p11UniSTS


Expression


Sequence


RefSeq Acc Id: ENSRNOT00000061105   ⟹   ENSRNOP00000085162
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl128,737,297 - 8,804,177 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000092276   ⟹   ENSRNOP00000081852
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl128,737,262 - 8,804,177 (-)Ensembl
RefSeq Acc Id: NM_001109061   ⟹   NP_001102531
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81213,851,088 - 13,917,992 (-)NCBI
mRatBN7.2128,737,262 - 8,804,177 (-)NCBI
Rnor_6.01210,496,273 - 10,561,335 (-)NCBI
Rnor_5.01212,597,402 - 12,663,842 (-)NCBI
Celera1210,565,691 - 10,631,673 (-)RGD
Sequence:
RefSeq Acc Id: XM_039089684   ⟹   XP_038945612
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81213,851,024 - 13,919,017 (-)NCBI
mRatBN7.2128,737,198 - 8,805,020 (-)NCBI
RefSeq Acc Id: XM_039089685   ⟹   XP_038945613
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81213,851,024 - 13,919,017 (-)NCBI
mRatBN7.2128,737,198 - 8,805,021 (-)NCBI
RefSeq Acc Id: XM_039089686   ⟹   XP_038945614
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81213,851,024 - 13,919,017 (-)NCBI
mRatBN7.2128,737,198 - 8,805,021 (-)NCBI
RefSeq Acc Id: XM_039089687   ⟹   XP_038945615
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81213,851,024 - 13,919,017 (-)NCBI
mRatBN7.2128,737,198 - 8,805,020 (-)NCBI
RefSeq Acc Id: XM_039089688   ⟹   XP_038945616
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81213,851,024 - 13,901,890 (-)NCBI
mRatBN7.2128,737,198 - 8,787,853 (-)NCBI
RefSeq Acc Id: XM_039089690   ⟹   XP_038945618
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81213,861,799 - 13,919,017 (-)NCBI
mRatBN7.2128,751,848 - 8,805,026 (-)NCBI
RefSeq Acc Id: XR_010056410
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81213,854,088 - 13,919,017 (-)NCBI
RefSeq Acc Id: NP_001102531   ⟸   NM_001109061
- UniProtKB: A6K1D1 (UniProtKB/TrEMBL),   A0A8I5ZYM4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_038945614   ⟸   XM_039089686
- Peptide Label: isoform X3
- UniProtKB: A0A8I5ZYM4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038945613   ⟸   XM_039089685
- Peptide Label: isoform X2
- UniProtKB: A0A8I5ZYM4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038945615   ⟸   XM_039089687
- Peptide Label: isoform X4
- UniProtKB: A0A8I5ZVW8 (UniProtKB/TrEMBL),   A0A8I5ZYM4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038945612   ⟸   XM_039089684
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZYM4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038945616   ⟸   XM_039089688
- Peptide Label: isoform X5
- UniProtKB: A0A8I5ZYM4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038945618   ⟸   XM_039089690
- Peptide Label: isoform X6
RefSeq Acc Id: ENSRNOP00000081852   ⟸   ENSRNOT00000092276
RefSeq Acc Id: ENSRNOP00000085162   ⟸   ENSRNOT00000061105
Protein Domains
Protein kinase

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1560888 AgrOrtholog
BioCyc Gene G2FUF-20078 BioCyc
Ensembl Genes ENSRNOG00000039819 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000061105 ENTREZGENE
  ENSRNOT00000061105.6 UniProtKB/TrEMBL
  ENSRNOT00000092276.2 UniProtKB/TrEMBL
Gene3D-CATH Transferase(Phosphotransferase) domain 1 UniProtKB/TrEMBL
InterPro Kinase-like_dom_sf UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/TrEMBL
  Ser/Thr_kinase_AS UniProtKB/TrEMBL
KEGG Report rno:498140 UniProtKB/TrEMBL
NCBI Gene 498140 ENTREZGENE
PANTHER CELL DIVISION PROTEIN KINASE UniProtKB/TrEMBL
  CYCLIN-DEPENDENT KINASE 8 UniProtKB/TrEMBL
Pfam Pkinase UniProtKB/TrEMBL
PhenoGen Cdk8 PhenoGen
PROSITE PROTEIN_KINASE_ATP UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/TrEMBL
  PROTEIN_KINASE_ST UniProtKB/TrEMBL
RatGTEx ENSRNOG00000039819 RatGTEx
SMART S_TKc UniProtKB/TrEMBL
Superfamily-SCOP SSF56112 UniProtKB/TrEMBL
UniProt A0A8I5ZVW8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZYM4 ENTREZGENE, UniProtKB/TrEMBL
  A6K1D1 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-11-25 Cdk8  cyclin-dependent kinase 8  RGD1560888  similar to Cell division protein kinase 8 (Protein kinase K35)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-05-24 RGD1560888  similar to Cell division protein kinase 8 (Protein kinase K35)  LOC100360585  cyclin-dependent kinase 8  Data merged from RGD:2321872 1643240 APPROVED
2010-05-06 LOC100360585  cyclin-dependent kinase 8      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-04-30 RGD1560888  similar to Cell division protein kinase 8 (Protein kinase K35)   RGD1560888_predicted  similar to Cell division protein kinase 8 (Protein kinase K35) (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1560888_predicted  similar to Cell division protein kinase 8 (Protein kinase K35) (predicted)  LOC498140  similar to Cell division protein kinase 8 (Protein kinase K35)  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC498140  similar to Cell division protein kinase 8 (Protein kinase K35)      Symbol and Name status set to provisional 70820 PROVISIONAL