Pan3 (poly(A) specific ribonuclease subunit PAN3) - Rat Genome Database

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Gene: Pan3 (poly(A) specific ribonuclease subunit PAN3) Rattus norvegicus
Analyze
Symbol: Pan3
Name: poly(A) specific ribonuclease subunit PAN3
RGD ID: 1590880
Description: Predicted to enable poly(A) binding activity. Predicted to contribute to poly(A)-specific ribonuclease activity. Predicted to be involved in nuclear-transcribed mRNA poly(A) tail shortening. Predicted to act upstream of or within deadenylation-dependent decapping of nuclear-transcribed mRNA; positive regulation of cytoplasmic mRNA processing body assembly; and protein targeting. Predicted to be part of PAN complex. Predicted to be active in P-body. Orthologous to human PAN3 (poly(A) specific ribonuclease subunit PAN3); PARTICIPATES IN microRNA pathway; RNA degradation pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; C60 fullerene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC360760; PAB-dependent poly(A)-specific ribonuclease subunit PAN3; PAN2-PAN3 deadenylation complex subunit PAN3; PAN3 poly(A) specific ribonuclease subunit; PAN3 polyA specific ribonuclease subunit homolog; PAN3 polyA specific ribonuclease subunit homolog (S. cerevisiae); similar to PABP-dependent poly(A) nuclease 3
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81212,512,835 - 12,637,066 (-)NCBIGRCr8
mRatBN7.2127,476,707 - 7,595,384 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl127,476,697 - 7,599,204 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.0129,214,116 - 9,331,901 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl129,216,536 - 9,331,195 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01211,333,266 - 11,449,831 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4128,046,162 - 8,165,081 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera129,218,136 - 9,336,110 (-)NCBICelera
Cytogenetic Map12p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
P-body  (IBA,ISO)
PAN complex  (IBA,ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Comprehensive gene review and curation RGD comprehensive gene curation
7. RNA decay machines: deadenylation by the Ccr4-not and Pan2-Pan3 complexes. Wahle E and Winkler GS, Biochim Biophys Acta. 2013 Jun-Jul;1829(6-7):561-70. doi: 10.1016/j.bbagrm.2013.01.003. Epub 2013 Jan 19.
Additional References at PubMed
PMID:12477932   PMID:14583602   PMID:18625844  


Genomics

Comparative Map Data
Pan3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81212,512,835 - 12,637,066 (-)NCBIGRCr8
mRatBN7.2127,476,707 - 7,595,384 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl127,476,697 - 7,599,204 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.0129,214,116 - 9,331,901 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl129,216,536 - 9,331,195 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01211,333,266 - 11,449,831 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4128,046,162 - 8,165,081 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera129,218,136 - 9,336,110 (-)NCBICelera
Cytogenetic Map12p11NCBI
PAN3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381328,138,193 - 28,295,335 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1328,138,506 - 28,295,335 (+)EnsemblGRCh38hg38GRCh38
GRCh371328,712,682 - 28,869,472 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361327,646,417 - 27,767,472 (+)NCBINCBI36Build 36hg18NCBI36
Celera139,787,744 - 9,944,258 (+)NCBICelera
Cytogenetic Map13q12.2NCBI
HuRef139,533,856 - 9,690,407 (+)NCBIHuRef
CHM1_11328,681,211 - 28,837,730 (+)NCBICHM1_1
T2T-CHM13v2.01327,361,098 - 27,517,568 (+)NCBIT2T-CHM13v2.0
Pan3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395147,363,018 - 147,485,310 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5147,366,971 - 147,485,312 (+)EnsemblGRCm39 Ensembl
GRCm385147,426,208 - 147,548,501 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5147,430,161 - 147,548,502 (+)EnsemblGRCm38mm10GRCm38
MGSCv375148,242,156 - 148,360,077 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365147,741,238 - 147,858,845 (+)NCBIMGSCv36mm8
Celera5145,424,005 - 145,541,898 (+)NCBICelera
Cytogenetic Map5G3NCBI
cM Map586.93NCBI
Pan3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554977,500,748 - 7,647,255 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554977,500,478 - 7,646,541 (+)NCBIChiLan1.0ChiLan1.0
PAN3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21427,723,636 - 27,886,390 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11318,827,987 - 18,990,992 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0139,420,405 - 9,579,859 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11327,797,325 - 27,921,266 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1327,798,607 - 27,921,266 (+)Ensemblpanpan1.1panPan2
PAN3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12511,416,321 - 11,550,830 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2511,417,657 - 11,550,810 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2511,479,225 - 11,613,731 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02511,544,373 - 11,678,148 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2511,545,635 - 11,678,130 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12511,440,197 - 11,574,226 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02511,432,789 - 11,566,165 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02511,474,666 - 11,609,590 (-)NCBIUU_Cfam_GSD_1.0
Pan3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945172,518,051 - 172,654,798 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647223,297,847 - 23,431,982 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647223,297,679 - 23,434,107 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PAN3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl115,487,138 - 5,614,452 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1115,487,019 - 5,614,458 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2115,173,907 - 5,301,062 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PAN3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.137,249,596 - 7,405,770 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl37,249,298 - 7,405,910 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605736,983,767 - 37,141,534 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pan3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477610,227,308 - 10,364,522 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477610,224,772 - 10,364,816 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Pan3
478 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:166
Count of miRNA genes:122
Interacting mature miRNAs:134
Transcripts:ENSRNOT00000001250, ENSRNOT00000044134, ENSRNOT00000071838
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300174Bw15Body weight QTL 152.93body mass (VT:0001259)body weight loss (CMO:0001399)1219318387Rat
2312418Kidm41Kidney mass QTL 413.70.0001kidney mass (VT:0002707)single kidney wet weight to body weight ratio (CMO:0000622)12119611090Rat
10755457Coatc14Coat color QTL 140.01759coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)12122591684Rat
6893681Bw109Body weight QTL 1092.30.004body mass (VT:0001259)body weight (CMO:0000012)12123297788Rat
1581516Cm56Cardiac mass QTL 564.20.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)12129333307Rat
1598855Bp294Blood pressure QTL 2943.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)12134851688Rat
7411660Foco28Food consumption QTL 2810.90.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12142110980Rat
9590086Insglur6Insulin/glucose ratio QTL 618.970.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)12142110980Rat
8694179Bw150Body weight QTL 1502.90.001body mass (VT:0001259)body weight gain (CMO:0000420)12142110980Rat
7411586Foco5Food consumption QTL 55.40.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12142110980Rat
7411595Foco9Food consumption QTL 940.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12142110980Rat
7411545Bw128Body weight QTL 1285.20.001body mass (VT:0001259)body weight gain (CMO:0000420)12142110980Rat
9590147Scort7Serum corticosterone level QTL 713.610.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)12142110980Rat
2303575Insul14Insulin level QTL 144blood insulin amount (VT:0001560)blood insulin level (CMO:0000349)12142450532Rat
737979Pia22Pristane induced arthritis QTL 2253.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)12144465750Rat
634351Apr5Acute phase response QTL 56.7blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)12144503507Rat
2302042Pia38Pristane induced arthritis QTL 383.50.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)12144503507Rat
7243862Mcs30Mammary carcinoma susceptibility QTL 308.62mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)127977298525593Rat
634350Apr4Acute phase response QTL 46orosomucoid 1 amount (VT:0010541)plasma orosomucoid 1 level (CMO:0001467)12117200546172005Rat
724526Uae3Urinary albumin excretion QTL 34.90.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)12390696910373166Rat
8552918Pigfal7Plasma insulin-like growth factor 1 level QTL 7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449546669029Rat
7411547Bw129Body weight QTL 1290.001body mass (VT:0001259)body weight gain (CMO:0000420)6556449546669029Rat
7411597Foco10Food consumption QTL 100.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12556449546669029Rat
7411641Foco19Food consumption QTL 1927.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12556449546669029Rat
8552964Pigfal17Plasma insulin-like growth factor 1 level QTL 173.5blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449546669029Rat
7411588Foco6Food consumption QTL 60.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12556449546669029Rat
8552912Pigfal6Plasma insulin-like growth factor 1 level QTL 65blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449846669029Rat
10059594Kidm46Kidney mass QTL 463.790.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)12610757946669029Rat
1600391Edcs2Endometrial carcinoma susceptibility QTL23.50.01uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)12683319017870186Rat
1302792Scl21Serum cholesterol level QTL 213.80.0011blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)12719673046669029Rat

Markers in Region
SGC34512  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2127,476,740 - 7,476,874 (+)MAPPERmRatBN7.2
mRatBN7.2424,652,330 - 24,652,466 (+)MAPPERmRatBN7.2
Rnor_6.0421,603,013 - 21,603,148NCBIRnor6.0
Rnor_6.0129,214,146 - 9,214,279NCBIRnor6.0
Rnor_5.01211,333,300 - 11,333,433UniSTSRnor5.0
Rnor_5.0421,535,195 - 21,535,330UniSTSRnor5.0
RGSC_v3.4422,160,538 - 22,160,673UniSTSRGSC3.4
RGSC_v3.4128,046,196 - 8,046,329UniSTSRGSC3.4
Celera129,218,170 - 9,218,303UniSTS
Celera420,152,579 - 20,152,714UniSTS
Cytogenetic Map4q12UniSTS
Cytogenetic Map12p11UniSTS
RH132266  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2127,476,782 - 7,476,979 (+)MAPPERmRatBN7.2
Rnor_6.0129,214,188 - 9,214,384NCBIRnor6.0
Rnor_5.01211,333,342 - 11,333,538UniSTSRnor5.0
RGSC_v3.4128,046,238 - 8,046,434UniSTSRGSC3.4
Celera129,218,212 - 9,218,408UniSTS
Cytogenetic Map12p11UniSTS
RH143488  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2127,489,650 - 7,489,751 (+)MAPPERmRatBN7.2
Rnor_6.0129,227,053 - 9,227,153NCBIRnor6.0
Rnor_5.01211,346,207 - 11,346,307UniSTSRnor5.0
RGSC_v3.4128,059,103 - 8,059,203UniSTSRGSC3.4
Celera129,231,077 - 9,231,177UniSTS
RH 3.4 Map1289.74UniSTS
Cytogenetic Map12p11UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 38 44 28 19 28 6 6 74 34 41 11 6
Low 5 13 13 13 2 5 1 2
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001419788 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_001068449 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006221249 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006221250 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006248842 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006248844 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006248845 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008758840 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039089924 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039089925 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039089926 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039089927 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039089928 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039089929 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039089930 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063271439 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063271441 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_346914 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010056399 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BC091375 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC103655 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ233080 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000012 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSRNOT00000044134   ⟹   ENSRNOP00000040388
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl127,476,697 - 7,599,204 (-)Ensembl
Rnor_6.0 Ensembl129,216,536 - 9,331,195 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000083249   ⟹   ENSRNOP00000076931
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl127,476,697 - 7,599,204 (-)Ensembl
RefSeq Acc Id: NM_001419788   ⟹   NP_001406717
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81212,512,835 - 12,631,492 (-)NCBI
mRatBN7.2127,476,711 - 7,595,384 (-)NCBI
RefSeq Acc Id: XM_006248842   ⟹   XP_006248904
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81212,512,835 - 12,637,066 (-)NCBI
mRatBN7.2127,476,707 - 7,595,379 (-)NCBI
Rnor_6.0129,214,116 - 9,331,897 (-)NCBI
Rnor_5.01211,333,266 - 11,449,831 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039089924   ⟹   XP_038945852
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81212,512,835 - 12,637,066 (-)NCBI
mRatBN7.2127,476,707 - 7,595,380 (-)NCBI
RefSeq Acc Id: XM_039089925   ⟹   XP_038945853
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81212,512,835 - 12,637,066 (-)NCBI
mRatBN7.2127,476,707 - 7,595,379 (-)NCBI
RefSeq Acc Id: XM_039089926   ⟹   XP_038945854
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81212,512,835 - 12,630,412 (-)NCBI
mRatBN7.2127,476,707 - 7,594,173 (-)NCBI
RefSeq Acc Id: XM_039089927   ⟹   XP_038945855
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81212,512,835 - 12,629,228 (-)NCBI
mRatBN7.2127,476,707 - 7,592,273 (-)NCBI
RefSeq Acc Id: XM_039089928   ⟹   XP_038945856
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81212,512,835 - 12,567,380 (-)NCBI
mRatBN7.2127,476,707 - 7,531,262 (-)NCBI
RefSeq Acc Id: XM_039089929   ⟹   XP_038945857
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81212,512,835 - 12,561,839 (-)NCBI
mRatBN7.2127,476,707 - 7,525,721 (-)NCBI
RefSeq Acc Id: XM_039089930   ⟹   XP_038945858
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81212,512,835 - 12,610,242 (-)NCBI
mRatBN7.2127,476,707 - 7,574,120 (-)NCBI
RefSeq Acc Id: XM_063271439   ⟹   XP_063127509
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81212,512,835 - 12,637,066 (-)NCBI
RefSeq Acc Id: XM_063271441   ⟹   XP_063127511
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81212,512,835 - 12,567,376 (-)NCBI
RefSeq Acc Id: XM_346914   ⟹   XP_346915
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81212,512,835 - 12,637,066 (-)NCBI
mRatBN7.2127,476,707 - 7,595,378 (-)NCBI
Rnor_6.0129,214,116 - 9,331,896 (-)NCBI
Rnor_5.01211,333,266 - 11,449,831 (-)NCBI
RGSC_v3.4128,046,162 - 8,165,081 (-)RGD
Sequence:
RefSeq Acc Id: XR_010056399
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81212,520,586 - 12,637,066 (-)NCBI
RefSeq Acc Id: XP_346915   ⟸   XM_346914
- Peptide Label: isoform X4
- UniProtKB: A0A8I5Y6J5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006248904   ⟸   XM_006248842
- Peptide Label: isoform X1
- UniProtKB: D4ADM2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000040388   ⟸   ENSRNOT00000044134
RefSeq Acc Id: XP_038945852   ⟸   XM_039089924
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038945853   ⟸   XM_039089925
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038945854   ⟸   XM_039089926
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038945855   ⟸   XM_039089927
- Peptide Label: isoform X7
RefSeq Acc Id: XP_038945858   ⟸   XM_039089930
- Peptide Label: isoform X9
RefSeq Acc Id: XP_038945856   ⟸   XM_039089928
- Peptide Label: isoform X8
RefSeq Acc Id: XP_038945857   ⟸   XM_039089929
- Peptide Label: isoform X9
RefSeq Acc Id: ENSRNOP00000076931   ⟸   ENSRNOT00000083249
RefSeq Acc Id: NP_001406717   ⟸   NM_001419788
RefSeq Acc Id: XP_063127509   ⟸   XM_063271439
- Peptide Label: isoform X5
RefSeq Acc Id: XP_063127511   ⟸   XM_063271441
- Peptide Label: isoform X9
Protein Domains
C3H1-type   Protein kinase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4ADM2-F1-model_v2 AlphaFold D4ADM2 1-740 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1590880 AgrOrtholog
BioCyc Gene G2FUF-20120 BioCyc
Ensembl Genes ENSRNOG00000000942 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000044134.7 UniProtKB/TrEMBL
  ENSRNOT00000083249.2 UniProtKB/TrEMBL
Gene3D-CATH 1.10.287.3700 UniProtKB/TrEMBL
  1.20.5.5160 UniProtKB/TrEMBL
  Transferase(Phosphotransferase) domain 1 UniProtKB/TrEMBL
InterPro Kinase-like_dom UniProtKB/TrEMBL
  PAN3 UniProtKB/TrEMBL
  Pan3_PK UniProtKB/TrEMBL
  Prot_kinase_cat_dom UniProtKB/TrEMBL
  Znf_CCCH UniProtKB/TrEMBL
  Znf_CCCH_sf UniProtKB/TrEMBL
KEGG Report rno:360760 UniProtKB/TrEMBL
NCBI Gene 360760 ENTREZGENE
PANTHER PAN2-PAN3 DEADENYLATION COMPLEX SUBUNIT PAN3 UniProtKB/TrEMBL
  PTHR12272 UniProtKB/TrEMBL
Pfam Pan3_PK UniProtKB/TrEMBL
PhenoGen Pan3 PhenoGen
PROSITE PROTEIN_KINASE_DOM UniProtKB/TrEMBL
  ZF_C3H1 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000000942 RatGTEx
SMART S_TKc UniProtKB/TrEMBL
  ZnF_C3H1 UniProtKB/TrEMBL
Superfamily-SCOP Kinase_like UniProtKB/TrEMBL
  SSF90229 UniProtKB/TrEMBL
UniProt A0A8I5Y6J5 ENTREZGENE, UniProtKB/TrEMBL
  D4ADM2 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-05-04 Pan3  poly(A) specific ribonuclease subunit PAN3  Pan3  PAN3 poly(A) specific ribonuclease subunit  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2014-04-11 Pan3  PAN3 poly(A) specific ribonuclease subunit  Pan3  PAN3 polyA specific ribonuclease subunit homolog (S. cerevisiae)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-05 Pan3  PAN3 polyA specific ribonuclease subunit homolog (S. cerevisiae)  LOC360760  similar to PABP-dependent poly(A) nuclease 3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-11-20 LOC360760  similar to PABP-dependent poly(A) nuclease 3      Symbol and Name status set to provisional 70820 PROVISIONAL