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Gene: Fkbp6 (FKBP prolyl isomerase 6) Rattus norvegicus
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Symbol: Fkbp6
Name: FKBP prolyl isomerase 6
Description: Predicted to have Hsp90 protein binding activity and identical protein binding activity. Involved in spermatogenesis. Predicted to localize to the cytosol and synaptonemal complex. Used to study male infertility. Human ortholog(s) of this gene implicated in Williams-Beuren syndrome. Orthologous to human FKBP6 (FKBP prolyl isomerase 6); INTERACTS WITH bisphenol A; 13-BETA-ETHYL-17-ALPHA-ETHYNYL-17-BETA-HYDROXYGON-4-EN-3-ONE (ortholog); 17alpha-ethynylestradiol (ortholog).
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 36 kDa FK506 binding protein; FK506 binding protein 6; FK506 binding protein 6, 36kDa; FK506-binding protein 6; FKBP-36; immunophilin FKBP36; inactive peptidyl-prolyl cis-trans isomerase FKBP6; inactive PPIase FKBP6; peptidyl-prolyl cis-trans isomerase; peptidyl-prolyl cis-trans isomerase FKBP6; PPiase; rotamase
Orthologs:
Homo sapiens (human) : FKBP6 (FKBP prolyl isomerase 6)  HGNC  Alliance
Mus musculus (house mouse) : Fkbp6 (FK506 binding protein 6)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fkbp6 (FKBP prolyl isomerase 6)
Pan paniscus (bonobo/pygmy chimpanzee) : FKBP6 (FKBP prolyl isomerase 6)
Canis lupus familiaris (dog) : FKBP6 (FKBP prolyl isomerase 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fkbp6 (FKBP prolyl isomerase 6)
Sus scrofa (pig) : FKBP6 (FKBP prolyl isomerase 6)
more info ...
Is Marker For: Strains:   TT/Sgn  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01224,365,941 - 24,438,088 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01226,363,264 - 26,435,311 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41222,474,002 - 22,544,784 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11222,464,474 - 22,476,654 (+)NCBI
Celera1223,082,103 - 23,152,967 (+)NCBICelera
Cytogenetic Map12q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Related Rat Strains
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Fkbp6
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1308926
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.