Gene: Map2k7 (mitogen activated protein kinase kinase 7) Rattus norvegicus
Symbol: Map2k7
Name: mitogen activated protein kinase kinase 7
Description: ENCODES a protein that exhibits ATP binding; JUN kinase kinase activity; magnesium ion binding; INVOLVED IN activation of JUN kinase activity; cellular response to sorbitol; JNK cascade; PARTICIPATES IN c-Jun N-terminal kinases MAPK signaling pathway; adenosine signaling pathway; FasL mediated signaling pathway; ASSOCIATED WITH Breast Neoplasms (ortholog); congestive heart failure (ortholog); Fibrosis (ortholog); FOUND IN cytosol; nucleus; cytoplasm (ortholog); INTERACTS WITH bisphenol A; cadmium dichloride; nickel sulfate
Type: protein-coding
Also known as: 2; c-Jun N-terminal kinase kinase 2; dual specificity mitogen-activated protein kinase kinase 7; JNK kinase 2; JNK-activating kinase 2; JNKK; JNKK 2; Jnkk2; MAP kinase kinase 7; MAPK/ERK kinase 7; MAPKK 7; Mapkk7; MEK 7; Mek7; Mkk7
Homo sapiens (human) : MAP2K7 (mitogen-activated protein kinase kinase 7)  HGNC  Alliance
Mus musculus (house mouse) : Map2k7 (mitogen-activated protein kinase kinase 7)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Map2k7 (mitogen-activated protein kinase kinase 7)
Pan paniscus (bonobo/pygmy chimpanzee) : MAP2K7 (mitogen-activated protein kinase kinase 7)
Canis lupus familiaris (dog) : MAP2K7 (mitogen-activated protein kinase kinase 7)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Map2k7 (mitogen-activated protein kinase kinase 7)
Sus scrofa (pig) : MAP2K7 (mitogen-activated protein kinase kinase 7)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0122,546,278 - 2,555,310 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0124,698,912 - 4,708,078 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4121,545,407 - 1,552,353 (-)NCBIRGSC3.4rn4RGSC3.4
Celera124,407,043 - 4,413,990 (+)NCBICelera
Cytogenetic Map12p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Map2k7
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1560043
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2019-01-30
Status: ACTIVE