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Gene: Actb (actin, beta) Rattus norvegicus
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Symbol: Actb
Name: actin, beta
Description: Exhibits protein kinase binding activity. Involved in several processes, including cellular response to electrical stimulus; regulation of cyclin-dependent protein serine/threonine kinase activity; and regulation of norepinephrine uptake. Localizes to several cellular components, including the cytoskeleton; membrane raft; and postsynaptic density. Used to study nonalcoholic fatty liver disease. Biomarker of temporal lobe epilepsy. Human ortholog(s) of this gene implicated in Baraitser-Winter syndrome. Orthologous to human ACTB (actin beta); PARTICIPATES IN auditory mechanotransduction pathway; INO80 family mediated chromatin remodeling pathway; mitochondria transport pathway; INTERACTS WITH (+)-catechin; (+)-epicatechin-3-O-gallate; (3,4-dihydroxyphenyl)acetic acid.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: actin, cytoplasmic 1; Actx; beta-actin; cytoplasmic beta-actin
Orthologs:
Homo sapiens (human) : ACTB (actin beta)  HGNC  Alliance
Mus musculus (house mouse) : Actb (actin, beta)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Actb (actin beta)
Pan paniscus (bonobo/pygmy chimpanzee) : ACTB (actin beta)
Canis lupus familiaris (dog) : ACTB (actin beta)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Actb (actin beta)
Sus scrofa (pig) : ACTB (actin beta)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01213,715,843 - 13,718,813 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01215,745,856 - 15,749,440 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41212,047,070 - 12,050,040 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11212,076,997 - 12,079,967 (+)NCBI
Celera1213,452,443 - 13,455,413 (+)NCBICelera
Cytogenetic Map12p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Actb
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 628837
Created: 2003-02-27
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.