Wasf3 (WASP family member 3) - Rat Genome Database

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Gene: Wasf3 (WASP family member 3) Rattus norvegicus
Analyze
Symbol: Wasf3
Name: WASP family member 3
RGD ID: 1592807
Description: Predicted to have actin binding activity. Predicted to be involved in several processes, including lamellipodium assembly; modification of postsynaptic actin cytoskeleton; and positive regulation of myelination. Predicted to localize to glutamatergic synapse; lamellipodium; and postsynapse. Orthologous to human WASF3 (WASP family member 3); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOC682937; similar to WAS protein family, member 3; WAS protein family, member 3; wiskott-Aldrich syndrome protein family member 3
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2128,563,805 - 8,660,799 (-)NCBI
Rnor_6.0 Ensembl1210,298,555 - 10,391,270 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01210,297,896 - 10,391,014 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01212,401,989 - 12,493,810 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1210,379,274 - 10,474,931 (-)NCBICelera
Cytogenetic Map12p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

Additional References at PubMed
PMID:16190876   PMID:16723544   PMID:21834987   PMID:23533145  


Genomics

Comparative Map Data
Wasf3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2128,563,805 - 8,660,799 (-)NCBI
Rnor_6.0 Ensembl1210,298,555 - 10,391,270 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01210,297,896 - 10,391,014 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01212,401,989 - 12,493,810 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1210,379,274 - 10,474,931 (-)NCBICelera
Cytogenetic Map12p11NCBI
WASF3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1326,557,683 - 26,688,948 (+)EnsemblGRCh38hg38GRCh38
GRCh381326,539,139 - 26,688,948 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371327,131,820 - 27,263,085 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361326,029,840 - 26,161,082 (+)NCBINCBI36hg18NCBI36
Build 341326,029,886 - 26,161,063NCBI
Celera138,256,077 - 8,332,052 (+)NCBI
Cytogenetic Map13q12.13NCBI
HuRef137,955,351 - 8,086,464 (+)NCBIHuRef
CHM1_11327,099,816 - 27,231,081 (+)NCBICHM1_1
Wasf3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395146,321,816 - 146,410,425 (+)NCBIGRCm39mm39
GRCm39 Ensembl5146,321,795 - 146,410,425 (+)Ensembl
GRCm385146,385,006 - 146,473,615 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5146,384,985 - 146,473,615 (+)EnsemblGRCm38mm10GRCm38
MGSCv375147,196,582 - 147,282,701 (+)NCBIGRCm37mm9NCBIm37
MGSCv365146,689,240 - 146,774,650 (+)NCBImm8
Celera5144,372,570 - 144,458,483 (+)NCBICelera
Cytogenetic Map5G3NCBI
Wasf3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554976,102,909 - 6,190,770 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554976,100,633 - 6,190,639 (+)NCBIChiLan1.0ChiLan1.0
WASF3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11326,250,171 - 26,328,553 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1326,250,171 - 26,328,553 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0137,849,687 - 7,980,979 (+)NCBIMhudiblu_PPA_v0panPan3
WASF3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12512,804,485 - 12,881,988 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2512,805,431 - 12,877,770 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2512,875,143 - 13,008,318 (-)NCBI
ROS_Cfam_1.02512,944,371 - 13,077,673 (-)NCBI
UMICH_Zoey_3.12512,830,485 - 12,963,635 (-)NCBI
UNSW_CanFamBas_1.02512,822,254 - 12,955,911 (-)NCBI
UU_Cfam_GSD_1.02512,873,760 - 13,006,959 (-)NCBI
Wasf3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945115,180,691 - 115,300,651 (+)NCBI
SpeTri2.0NW_004936948345,942 - 465,323 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
WASF3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl114,261,177 - 4,366,254 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1114,261,121 - 4,366,258 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2113,736,220 - 3,791,727 (+)NCBISscrofa10.2Sscrofa10.2susScr3
WASF3
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.135,805,115 - 5,934,764 (+)NCBI
ChlSab1.1 Ensembl35,889,263 - 5,931,662 (+)Ensembl
Vero_WHO_p1.0NW_02366605738,489,195 - 38,621,738 (-)NCBI
Wasf3
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462477611,863,880 - 11,985,087 (-)NCBI

Position Markers
BF404808  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2128,569,363 - 8,569,490 (+)MAPPER
Rnor_6.01210,303,271 - 10,303,397NCBIRnor6.0
Rnor_5.01212,407,364 - 12,407,490UniSTSRnor5.0
Celera1210,384,660 - 10,384,786UniSTS
RH 3.4 Map12110.7UniSTS
BE119348  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2128,571,663 - 8,571,829 (+)MAPPER
Rnor_6.01210,305,570 - 10,305,735NCBIRnor6.0
Rnor_5.01212,409,663 - 12,409,828UniSTSRnor5.0
Celera1210,386,960 - 10,387,125UniSTS
RH 3.4 Map12108.6UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300174Bw15Body weight QTL 152.93body mass (VT:0001259)body weight loss (CMO:0001399)12111765163Rat
2312418Kidm41Kidney mass QTL 413.70.0001kidney mass (VT:0002707)single kidney wet weight to body weight ratio (CMO:0000622)12122650917Rat
10450854Stl34Serum triglyceride level QTL 343.50.05blood LDL triglyceride amount (VT:0010699)blood lipoprotein triglyceride level (CMO:0002685)12122853017Rat
10755457Coatc14Coat color QTL 140.01759coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)12123035872Rat
6893681Bw109Body weight QTL 1092.30.004body mass (VT:0001259)body weight (CMO:0000012)12123758197Rat
1581516Cm56Cardiac mass QTL 564.20.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)12130749723Rat
1598855Bp294Blood pressure QTL 2943.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)12136919844Rat
7387292Kidm42Kidney mass QTL 423.030.0004kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)12138334225Rat
9590086Insglur6Insulin/glucose ratio QTL 618.970.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)1215081045150810Rat
9590147Scort7Serum corticosterone level QTL 713.610.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)1215081045150810Rat
7411545Bw128Body weight QTL 1285.20.001body mass (VT:0001259)body weight gain (CMO:0000420)1215081045150810Rat
7411586Foco5Food consumption QTL 55.40.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)1215081045150810Rat
7411660Foco28Food consumption QTL 2810.90.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)1215081045150810Rat
7411595Foco9Food consumption QTL 940.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)1215081045150810Rat
8694179Bw150Body weight QTL 1502.90.001body mass (VT:0001259)body weight gain (CMO:0000420)1215081045150810Rat
2303575Insul14Insulin level QTL 144blood insulin amount (VT:0001560)blood insulin level (CMO:0000349)1249257845492578Rat
737979Pia22Pristane induced arthritis QTL 2253.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)12247568747475687Rat
634351Apr5Acute phase response QTL 56.7blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)12251344247513442Rat
2302042Pia38Pristane induced arthritis QTL 383.50.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)12251344247513442Rat
634350Apr4Acute phase response QTL 46orosomucoid 1 amount (VT:0010541)plasma orosomucoid 1 level (CMO:0001467)12421005149210051Rat
724526Uae3Urinary albumin excretion QTL 34.90.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)12540609412355490Rat
1600391Edcs2Endometrial carcinoma susceptibility QTL23.50.01uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)12824960820590080Rat
1302792Scl21Serum cholesterol level QTL 213.80.0011blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)12895459327911196Rat
7411547Bw129Body weight QTL 1290.001body mass (VT:0001259)body weight gain (CMO:0000420)6922362652716770Rat
7411588Foco6Food consumption QTL 60.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12922362652716770Rat
7411597Foco10Food consumption QTL 100.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12922362652716770Rat
7411641Foco19Food consumption QTL 1927.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12922362652716770Rat
8552918Pigfal7Plasma insulin-like growth factor 1 level QTL 7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12922362652716770Rat
8552964Pigfal17Plasma insulin-like growth factor 1 level QTL 173.5blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12922362652716770Rat
8552912Pigfal6Plasma insulin-like growth factor 1 level QTL 65blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12922363052716770Rat
10059594Kidm46Kidney mass QTL 463.790.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)12978983452716770Rat
2293086Iddm30Insulin dependent diabetes mellitus QTL 303.82blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)121017588931975590Rat
61331Eau2Experimental allergic uveoretinitis QTL 20.0005uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)121025689031723732Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:55
Count of miRNA genes:53
Interacting mature miRNAs:54
Transcripts:ENSRNOT00000071567
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 74 1 7
Low 1 12 34 27 5 27 1 1 34 32 2 1
Below cutoff 2 30 17 14 8 14 6 8 2 9 6

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_001061259 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006221252 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008758886 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598587 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017604428 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017604429 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017604430 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039089931 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039089933 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039089934 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039089935 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039089936 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039089937 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039089938 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039089939 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CH474012 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000224 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000071567   ⟹   ENSRNOP00000065380
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1210,299,112 - 10,335,499 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000092340   ⟹   ENSRNOP00000075868
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1210,315,476 - 10,391,270 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000092627   ⟹   ENSRNOP00000075856
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1210,298,555 - 10,307,265 (-)Ensembl
RefSeq Acc Id: XM_001061259   ⟹   XP_001061259
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera1210,379,274 - 10,452,613 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006221252   ⟹   XP_006221314
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera1210,379,274 - 10,474,931 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008758886   ⟹   XP_008757108
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera1210,379,274 - 10,474,916 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017598587   ⟹   XP_017454076
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01210,297,896 - 10,391,014 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017604428   ⟹   XP_017459917
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera1210,379,274 - 10,456,233 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017604429   ⟹   XP_017459918
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera1210,379,274 - 10,474,923 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017604430   ⟹   XP_017459919
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera1210,379,274 - 10,474,931 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039089931   ⟹   XP_038945859
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2128,563,805 - 8,619,863 (-)NCBI
RefSeq Acc Id: XM_039089933   ⟹   XP_038945861
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2128,563,805 - 8,619,862 (-)NCBI
RefSeq Acc Id: XM_039089934   ⟹   XP_038945862
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2128,563,805 - 8,660,799 (-)NCBI
RefSeq Acc Id: XM_039089935   ⟹   XP_038945863
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2128,563,805 - 8,638,391 (-)NCBI
RefSeq Acc Id: XM_039089936   ⟹   XP_038945864
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2128,563,805 - 8,660,773 (-)NCBI
RefSeq Acc Id: XM_039089937   ⟹   XP_038945865
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2128,563,805 - 8,573,166 (-)NCBI
RefSeq Acc Id: XM_039089938   ⟹   XP_038945866
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2128,563,805 - 8,573,321 (-)NCBI
RefSeq Acc Id: XM_039089939   ⟹   XP_038945867
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2128,563,805 - 8,573,166 (-)NCBI
Reference Sequences
RefSeq Acc Id: XP_001061259   ⟸   XM_001061259
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_006221314   ⟸   XM_006221252
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_008757108   ⟸   XM_008758886
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_017459919   ⟸   XM_017604430
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_017459918   ⟸   XM_017604429
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_017459917   ⟸   XM_017604428
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_017454076   ⟸   XM_017598587
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSRNOP00000075868   ⟸   ENSRNOT00000092340
RefSeq Acc Id: ENSRNOP00000075856   ⟸   ENSRNOT00000092627
RefSeq Acc Id: ENSRNOP00000065380   ⟸   ENSRNOT00000071567
RefSeq Acc Id: XP_038945862   ⟸   XM_039089934
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038945864   ⟸   XM_039089936
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038945863   ⟸   XM_039089935
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038945859   ⟸   XM_039089931
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038945861   ⟸   XM_039089933
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038945866   ⟸   XM_039089938
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038945865   ⟸   XM_039089937
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038945867   ⟸   XM_039089939
- Peptide Label: isoform X3
Protein Domains
WH2

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1592807 AgrOrtholog
Ensembl Genes ENSRNOG00000048898 Ensembl, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000065380 UniProtKB/TrEMBL
  ENSRNOP00000075856 UniProtKB/TrEMBL
  ENSRNOP00000075868 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000071567 UniProtKB/TrEMBL
  ENSRNOT00000092340 UniProtKB/TrEMBL
  ENSRNOT00000092627 UniProtKB/TrEMBL
InterPro SCAR/WAVE_fam UniProtKB/TrEMBL
  WH2_dom UniProtKB/TrEMBL
NCBI Gene 682937 ENTREZGENE
PANTHER PTHR12902 UniProtKB/TrEMBL
Pfam WH2 UniProtKB/TrEMBL
PhenoGen Wasf3 PhenoGen
PROSITE WH2 UniProtKB/TrEMBL
SMART WH2 UniProtKB/TrEMBL
UniProt A0A0U1RRY0_RAT UniProtKB/TrEMBL
  A0A0U1RRZ0_RAT UniProtKB/TrEMBL
  M0R7F3_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-04-02 Wasf3  WASP family member 3  Wasf3  WAS protein family, member 3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-08-13 Wasf3  WAS protein family, member 3  LOC682937  similar to WAS protein family, member 3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-11-20 LOC682937  similar to WAS protein family, member 3      Symbol and Name status set to provisional 70820 PROVISIONAL