Zdhhc4 (zinc finger DHHC-type palmitoyltransferase 4)

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Gene: Zdhhc4 (zinc finger DHHC-type palmitoyltransferase 4) Rattus norvegicus

Analyze

Symbol:

Zdhhc4

Name:

zinc finger DHHC-type palmitoyltransferase 4

RGD ID:

1308389

Description:

Predicted to have protein-cysteine S-palmitoyltransferase activity. Predicted to be involved in protein phosphopantetheinylation. Predicted to localize to Golgi apparatus and endoplasmic reticulum. Orthologous to human ZDHHC4 (zinc finger DHHC-type palmitoyltransferase 4); INTERACTS WITH (+)-schisandrin B; 2,4,6-trinitrotoluene; bisphenol A.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Also known as:

DHHC-4; LOC304291; membrane-associated DHHC4 zinc finger protein; MGC108810; palmitoyltransferase ZDHHC4; probable palmitoyltransferase ZDHHC4; zinc finger DHHC domain-containing protein 4; zinc finger, DHHC domain containing 4; zinc finger, DHHC-type containing 4

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

Latest Assembly:

Rnor_6.0 - RGSC Genome Assembly v6.0

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	12	11,230,864 - 11,244,898 (+)	NCBI
Rnor_6.0 Ensembl	12	13,284,532 - 13,298,575 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0	12	13,284,508 - 13,298,519 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	12	15,324,890 - 15,339,326 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	12	11,594,931 - 11,605,771 (+)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	12	11,624,858 - 11,635,700 (+)	NCBI
Celera	12	13,027,249 - 13,038,153 (+)	NCBI		Celera
Cytogenetic Map	12	p11	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (EXP)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2,4,6-trinitrotoluene (EXP)

3,4-methylenedioxymethamphetamine (ISO)

all-trans-retinoic acid (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP)

bisphenol F (ISO)

cisplatin (ISO)

copper(II) sulfate (ISO)

cyclosporin A (ISO)

dibutyl phthalate (ISO)

fonofos (ISO)

gentamycin (EXP)

parathion (ISO)

sodium arsenite (EXP)

Soman (EXP)

sunitinib (ISO)

terbufos (ISO)

tert-butyl hydroperoxide (ISO)

tetrachloromethane (EXP)

tremolite asbestos (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

peptidyl-L-cysteine S-palmitoylation (IBA)

protein phosphopantetheinylation (IEA)

protein targeting to membrane (IBA)

Cellular Component

endoplasmic reticulum (IBA,IEA,ISO,ISS)

endoplasmic reticulum membrane (IEA)

Golgi apparatus (IBA,IEA,ISO)

Golgi membrane (IEA)

integral component of membrane (IEA)

plasma membrane (IEA)

Molecular Function

protein binding (ISO)

protein-cysteine S-palmitoyltransferase activity (IBA,IEA)

References

References - curated


1.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	RGD automated data pipeline
3.	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4.	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12477932	PMID:15489334	PMID:16647879	PMID:21926431

Genomics

Comparative Map Data

Zdhhc4
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	12	11,230,864 - 11,244,898 (+)	NCBI
Rnor_6.0 Ensembl	12	13,284,532 - 13,298,575 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0	12	13,284,508 - 13,298,519 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	12	15,324,890 - 15,339,326 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	12	11,594,931 - 11,605,771 (+)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	12	11,624,858 - 11,635,700 (+)	NCBI
Celera	12	13,027,249 - 13,038,153 (+)	NCBI		Celera
Cytogenetic Map	12	p11	NCBI

ZDHHC4
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38.p13 Ensembl	7	6,577,434 - 6,589,374 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh38	7	6,577,413 - 6,589,374 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh37	7	6,617,085 - 6,629,005 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	7	6,584,664 - 6,595,505 (+)	NCBI	NCBI36		hg18	NCBI36
Build 34	7	6,391,381 - 6,402,220	NCBI
Celera	7	6,106,568 - 6,118,126 (-)	NCBI
Cytogenetic Map	7	p22.1	NCBI
HuRef	7	6,488,605 - 6,501,092 (+)	NCBI		HuRef
CHM1_1	7	6,616,691 - 6,628,236 (+)	NCBI		CHM1_1
CRA_TCAGchr7v2	7	6,663,507 - 6,675,503 (+)	NCBI

Zdhhc4
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	5	143,302,244 - 143,315,007 (-)	NCBI	GRCm39		mm39
GRCm39 Ensembl	5	143,302,244 - 143,315,011 (-)	Ensembl
GRCm38	5	143,316,489 - 143,329,268 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	5	143,316,489 - 143,329,256 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	5	144,078,170 - 144,090,905 (-)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	5	143,581,631 - 143,594,366 (-)	NCBI			mm8
Celera	5	140,361,482 - 140,374,217 (-)	NCBI		Celera
Cytogenetic Map	5	G2	NCBI

Zdhhc4
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955460	13,119,699 - 13,132,835 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955460	13,119,672 - 13,133,688 (-)	NCBI	ChiLan1.0	ChiLan1.0

ZDHHC4
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	7	6,770,876 - 6,782,439 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	7	6,770,964 - 6,782,439 (+)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	7	6,855,657 - 6,867,537 (-)	NCBI	Mhudiblu_PPA_v0		panPan3

ZDHHC4
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1 Ensembl	6	11,893,081 - 11,924,929 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
CanFam3.1	6	11,893,007 - 11,911,657 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1

Zdhhc4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
SpeTri2.0	NW_004936765	101,152 - 111,249 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ZDHHC4
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	3	4,610,702 - 4,643,691 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	3	4,628,295 - 4,643,742 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

ZDHHC4
(Chlorocebus sabaeus - African green monkey)

Vervet Assembly	Chr	Position (strand)	Source	Genome Browsers
Vervet Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	28	15,788,451 - 15,804,072 (+)	NCBI
ChlSab1.1 Ensembl	28	15,792,215 - 15,804,713 (+)	Ensembl

Zdhhc4
(Heterocephalus glaber - naked mole-rat)

Molerat Assembly	Chr	Position (strand)	Source	Genome Browsers
Molerat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624740	30,759,134 - 30,768,802 (-)	NCBI

Position Markers

RH141332

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Rnor_6.0	12	13,298,193 - 13,298,406	NCBI	Rnor6.0
Rnor_5.0	12	15,339,000 - 15,339,213	UniSTS	Rnor5.0
RGSC_v3.4	12	11,605,526 - 11,605,739	UniSTS	RGSC3.4
Celera	12	13,037,835 - 13,038,048	UniSTS
Cytogenetic Map	12	p11	UniSTS

RH141786

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Rnor_6.0	12	13,289,324 - 13,289,530	NCBI	Rnor6.0
Rnor_5.0	12	15,329,586 - 15,329,792	UniSTS	Rnor5.0
RGSC_v3.4	12	11,596,657 - 11,596,863	UniSTS	RGSC3.4
Celera	12	13,028,972 - 13,029,178	UniSTS
Cytogenetic Map	12	p11	UniSTS

QTLs in Region (Rnor_6.0)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2312418	Kidm41	Kidney mass QTL 41	3.7	0.0001	kidney mass (VT:0002707)	single kidney wet weight to body weight ratio (CMO:0000622)	12	1	22650917	Rat
10450854	Stl34	Serum triglyceride level QTL 34	3.5	0.05	blood LDL triglyceride amount (VT:0010699)	blood lipoprotein triglyceride level (CMO:0002685)	12	1	22853017	Rat
10755457	Coatc14	Coat color QTL 14		0.01759	coat/hair pigmentation trait (VT:0010463)	pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)	12	1	23035872	Rat
6893681	Bw109	Body weight QTL 109	2.3	0.004	body mass (VT:0001259)	body weight (CMO:0000012)	12	1	23758197	Rat
1581516	Cm56	Cardiac mass QTL 56	4.2	0.05	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	12	1	30749723	Rat
1598855	Bp294	Blood pressure QTL 294	3.5		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	12	1	36919844	Rat
7387292	Kidm42	Kidney mass QTL 42	3.03	0.0004	kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	12	1	38334225	Rat
9590086	Insglur6	Insulin/glucose ratio QTL 6	18.97	0.001	blood insulin amount (VT:0001560)	calculated plasma insulin level (CMO:0002170)	12	150810	45150810	Rat
9590147	Scort7	Serum corticosterone level QTL 7	13.61	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	12	150810	45150810	Rat
7411545	Bw128	Body weight QTL 128	5.2	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	12	150810	45150810	Rat
7411586	Foco5	Food consumption QTL 5	5.4	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	150810	45150810	Rat
7411660	Foco28	Food consumption QTL 28	10.9	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	150810	45150810	Rat
7411595	Foco9	Food consumption QTL 9	4	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	150810	45150810	Rat
8694179	Bw150	Body weight QTL 150	2.9	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	12	150810	45150810	Rat
2303575	Insul14	Insulin level QTL 14	4		blood insulin amount (VT:0001560)	blood insulin level (CMO:0000349)	12	492578	45492578	Rat
737979	Pia22	Pristane induced arthritis QTL 22	53.1		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	12	2475687	47475687	Rat
634351	Apr5	Acute phase response QTL 5	6.7		blood interleukin-6 amount (VT:0008595)	plasma interleukin-6 level (CMO:0001927)	12	2513442	47513442	Rat
2302042	Pia38	Pristane induced arthritis QTL 38	3.5	0.001	blood immunoglobulin amount (VT:0002460)	serum immunoglobulin G1 level (CMO:0002115)	12	2513442	47513442	Rat
634350	Apr4	Acute phase response QTL 4	6		orosomucoid 1 amount (VT:0010541)	plasma orosomucoid 1 level (CMO:0001467)	12	4210051	49210051	Rat
1600391	Edcs2	Endometrial carcinoma susceptibility QTL2	3.5	0.01	uterus morphology trait (VT:0001120)	percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)	12	8249608	20590080	Rat
1302792	Scl21	Serum cholesterol level QTL 21	3.8	0.0011	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	12	8954593	27911196	Rat
7411547	Bw129	Body weight QTL 129		0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	6	9223626	52716770	Rat
7411588	Foco6	Food consumption QTL 6		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	9223626	52716770	Rat
7411597	Foco10	Food consumption QTL 10		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	9223626	52716770	Rat
7411641	Foco19	Food consumption QTL 19	27.7	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	9223626	52716770	Rat
8552918	Pigfal7	Plasma insulin-like growth factor 1 level QTL 7			blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	12	9223626	52716770	Rat
8552964	Pigfal17	Plasma insulin-like growth factor 1 level QTL 17	3.5		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	12	9223626	52716770	Rat
8552912	Pigfal6	Plasma insulin-like growth factor 1 level QTL 6	5		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	12	9223630	52716770	Rat
10059594	Kidm46	Kidney mass QTL 46	3.79	0.025	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	12	9789834	52716770	Rat
2293086	Iddm30	Insulin dependent diabetes mellitus QTL 30	3.82		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	12	10175889	31975590	Rat
61331	Eau2	Experimental allergic uveoretinitis QTL 2		0.0005	uvea integrity trait (VT:0010551)	experimental autoimmune uveitis score (CMO:0001504)	12	10256890	31723732	Rat
1331739	Hrtrt14	Heart rate QTL 14	3.56232		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	12	11764995	14489679	Rat
1300157	Rf21	Renal function QTL 21	4.4		renal blood flow trait (VT:2000006)	absolute change in renal blood flow rate (CMO:0001168)	12	11764995	37522089	Rat
1331786	Kidm11	Kidney mass QTL 11	3.571		kidney mass (VT:0002707)	right kidney wet weight (CMO:0000082)	12	13127211	27285590	Rat
1331755	Bp219	Blood pressure QTL 219	3.041		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	12	13127211	31723688	Rat
1331761	Bp218	Blood pressure QTL 218	2.973		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	12	13127211	50320041	Rat

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	54
Count of miRNA genes:	51
Interacting mature miRNAs:	54
Transcripts:	ENSRNOT00000001447
Prediction methods:	Microtar, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	3	35	51	36	17	36		2	66	35	41	11
Low		8	6	5	2	5	8	9	8				8
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001013123	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006248876	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008768962	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039089359	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039089360	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039089361	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039089362	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC126572	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY886523	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC089831	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474012	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ214800	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000224	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000084045 ⟹ ENSRNOP00000073588

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	12	13,284,532 - 13,298,575 (+)	Ensembl

RefSeq Acc Id:

NM_001013123 ⟹ NP_001013141

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	12	11,233,981 - 11,244,890 (+)	NCBI
Rnor_6.0	12	13,287,601 - 13,298,511 (+)	NCBI
Rnor_5.0	12	15,324,890 - 15,339,326 (+)	NCBI
RGSC_v3.4	12	11,594,931 - 11,605,771 (+)	RGD
Celera	12	13,027,249 - 13,038,153 (+)	RGD

Sequence:

show sequence

AAAAAAAAAAAAAAAAAAAAGCAGGCCTCTTTGTTCATCTTGAGAATGGCCTAGGGCTTACCCA
CCGATCTGATCGTGAATCTCAACTGCAGGAGTGAACCCGGGGCCGGAATACGTGCTGGGGAGAA
ATCCCTCAGCAGCAGCTGCTCATGCTGTCTCTTCCTTCACAGCCTCCAGCATGGACTTCCTGGT
TCTCTTCTCGTTCTACCTGGCCTTCTTACTGATTTGTGTCATCATGATCTGCATCTTCACGAAA
AGCCAGCGTTTGAAAGCTGTGGTCCTGGGAGGAGCACAGGTATGCGCCCGTGTAACCCCACAGT
GCTTCCAGAGGGCCGTGCAGACGCTCCTTCATCAGCTCTTCCACACACGCCACCCGGCCTTCCT
TGCCTTGCACCTGCTCCTGCAAGGGCTAGTTTACGCGGAATACACCTACGAAGTCTTCAGCTAC
TGCCGCGAGCTGGAGTTCTCCCTGCCTTGCCTTCTCCTGCCCTACGTGCTGCTGAGTGTGAACC
TGGTCTTCTTCACCCTGACTTGTTCCACCAATCCTGGAACCATCACTAAAACGAACGTGTTATT
ACTGCTGCAAGTCTATGAATTCGATGAGGTGATGTTTCCAAAGAACTCGAGGTGCTCCACCTGT
GACTTAAGGAAACCAGCGCGCTCCAAGCACTGCAGGGTGTGTGACCGGTGTGTGCACCGCTTCG
ACCATCACTGTGTTTGGGTGAACAACTGCATTGGGGCCTGGAACACCGGGTACTTCCTCATCTA
CCTCCTGACACTGACAGCCTCTGCCGCCACCATAGCCATCCTGAGTGCCGCCTTTCTGCTCCGC
CTAGTGGCAGTGTCAAATCTCTACCAGGAAACTTACCTGGATGACTTGGGGCGTTTCCAGGCTG
TGGACACAGGCTTTCTCATTCAGCACCTGTTCCTGGCTTTCCCAAGGATTATCTTCCTGCTGGG
CTTTGTCATCGTCCTGAGCTTGCTCCTGGCTGGCTACCTGTGCTTTGCTTTGTACCTGGCTGCC
ACCAACCAGACCACAAATGAATGGTATAGAGGCGACTGGGCCTGGTGCCAGCACTGGCCTCTGG
TGGCCTGGTCCCCATCAGCCGAGCCCCAGATCCACCAGAATATTTATTCCCATGGGCTTTGGAG
CAACCTTCAAGAGGTCTTTATACCTGCTACCCCCAGTTACAAGAAAAAGAAGAGATAGAAGGGA
GGTGTCCAGCCTTTTGAATACAGTACACAGCTATTTGTAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_006248876 ⟹ XP_006248938

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	12	11,230,865 - 11,244,898 (+)	NCBI
Rnor_6.0	12	13,284,508 - 13,298,519 (+)	NCBI
Rnor_5.0	12	15,324,890 - 15,339,326 (+)	NCBI

Sequence:

show sequence

GCACTGATGACGCCATGGACGCGCCGGAAGTCTCCGGGAGCGCTCAGCCGGGGTCAGCTGGCAG
CGGCTGACAGTTGGCCAGGCTTGGGCCACTTCCAGCCTCCTGGAACAGTCATGTCGCCGGTTTT
GCGTGTGCCGAATTCATAGTGCTGCCCCAGCAGAGCTGCTATCTGAATTCTCCGTGGATGTGGC
AAAGGGGAATGAACGCTAACGGTGTCGCTGGAAGTGTCCGACCTAGAGAAATATGTAGACTGGA
AACCTGTTACCTTCCTCCAGCATGGACTTCCTGGTTCTCTTCTCGTTCTACCTGGCCTTCTTAC
TGATTTGTGTCATCATGATCTGCATCTTCACGAAAAGCCAGCGTTTGAAAGCTGTGGTCCTGGG
AGGAGCACAGGTATGCGCCCGTGTAACCCCACAGTGCTTCCAGAGGGCCGTGCAGACGCTCCTT
CATCAGCTCTTCCACACACGCCACCCGGCCTTCCTTGCCTTGCACCTGCTCCTGCAAGGGCTAG
TTTACGCGGAATACACCTACGAAGTCTTCAGCTACTGCCGCGAGCTGGAGTTCTCCCTGCCTTG
CCTTCTCCTGCCCTACGTGCTGCTGAGTGTGAACCTGGTCTTCTTCACCCTGACTTGTTCCACC
AATCCTGGAACCATCACTAAAACGAACGTGTCATTACTGCTGCAAGTCTATGAATTCGATGAGG
TGATGTTTCCAAAGAACTCGAGGTGCTCCACCTGTGACTTAAGGAAACCAGCGCGCTCCAAGCA
CTGCAGGGTGTGTGACCGGTGTGTGCACCGCTTCGACCATCACTGTGTTTGGGTGAACAACTGC
ATTGGGGCCTGGAACACCGGGTACTTCCTCATCTACCTCCTGACACTGACAGCCTCTGCCGCCA
CCATAGCCATCCTGAGTGCCGCCTTTCTGCTCCGCCTAGTGGCAGTGTCAAATCTCTACCAGGA
AACTTACCTGGATGACTTGGGGCGTTTCCAGGCTGTGGACACAGGCTTTCTCATTCAGCACCTG
TTCCTGGCTTTCCCAAGGATTATCTTCCTGCTGGGCTTTGTCATCGTCCTGAGCTTGCTCCTGG
CTGGCTACCTGTGCTTTGCTTTGTACCTGGCTGCCACCAACCAGACCACAAATGAATGGTATAG
AGGCGACTGGGCCTGGTGCCAGCACTGGCCTCTGGTGGCCTGGTCCCCATCAGCCGAGCCCCAG
ATCCACCAGAATATTTATTCCCATGGGCTTTGGAGCAACCTTCAAGAGGTCTTTATACCTGCTA
CCCCCAGTTACAAGAAAAAGAAGAGATAGAAGGGAGGTGTCCAGCCTTTTGAATACAGTACACA
GCTATTTGTACTCATGGA

hide sequence

RefSeq Acc Id:

XM_008768962 ⟹ XP_008767184

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	12	11,230,864 - 11,244,898 (+)	NCBI
Rnor_6.0	12	13,284,508 - 13,298,519 (+)	NCBI

Sequence:

show sequence

GCACTGATGACGCCATGGACGCGCCGGAAGTCTCCGGGAGCGCTCAGCCGGGGTCAGCTGGCAG
CGGCTGACAGTTGGCCAGGCTTGGGCCACTTCCAGCCTCCTGGAACAGTCATGTCGCCGGTTTT
GCGTGTGCCGAATTCATAGTGCTGCCCCAGCAGAGCTGCTATCTGAATTCTCCGTGGATGTGGC
AAAGGGGAATGAACGCTAACGGTGTCGCTGGAAGTGTCCGACCTAGAGAAATATGTAGACTGGA
AACCTGTTACCTTGTGGAGAACCGTTGCCTTAAGGGACTGTGATGGAGAATGACAGAGAATGTG
TGACATCTTCCACATGCCTGCAAGCATTCACTTTCGAGCACTGCCCCACCAAACATCAGACACC
GAAGAAAAGCCTCCAGCATGGACTTCCTGGTTCTCTTCTCGTTCTACCTGGCCTTCTTACTGAT
TTGTGTCATCATGATCTGCATCTTCACGAAAAGCCAGCGTTTGAAAGCTGTGGTCCTGGGAGGA
GCACAGGTATGCGCCCGTGTAACCCCACAGTGCTTCCAGAGGGCCGTGCAGACGCTCCTTCATC
AGCTCTTCCACACACGCCACCCGGCCTTCCTTGCCTTGCACCTGCTCCTGCAAGGGCTAGTTTA
CGCGGAATACACCTACGAAGTCTTCAGCTACTGCCGCGAGCTGGAGTTCTCCCTGCCTTGCCTT
CTCCTGCCCTACGTGCTGCTGAGTGTGAACCTGGTCTTCTTCACCCTGACTTGTTCCACCAATC
CTGGAACCATCACTAAAACGAACGTGTCATTACTGCTGCAAGTCTATGAATTCGATGAGGTGAT
GTTTCCAAAGAACTCGAGGTGCTCCACCTGTGACTTAAGGAAACCAGCGCGCTCCAAGCACTGC
AGGGTGTGTGACCGGTGTGTGCACCGCTTCGACCATCACTGTGTTTGGGTGAACAACTGCATTG
GGGCCTGGAACACCGGGTACTTCCTCATCTACCTCCTGACACTGACAGCCTCTGCCGCCACCAT
AGCCATCCTGAGTGCCGCCTTTCTGCTCCGCCTAGTGGCAGTGTCAAATCTCTACCAGGAAACT
TACCTGGATGACTTGGGGCGTTTCCAGGCTGTGGACACAGGCTTTCTCATTCAGCACCTGTTCC
TGGCTTTCCCAAGGATTATCTTCCTGCTGGGCTTTGTCATCGTCCTGAGCTTGCTCCTGGCTGG
CTACCTGTGCTTTGCTTTGTACCTGGCTGCCACCAACCAGACCACAAATGAATGGTATAGAGGC
GACTGGGCCTGGTGCCAGCACTGGCCTCTGGTGGCCTGGTCCCCATCAGCCGAGCCCCAGATCC
ACCAGAATATTTATTCCCATGGGCTTTGGAGCAACCTTCAAGAGGTCTTTATACCTGCTACCCC
CAGTTACAAGAAAAAGAAGAGATAGAAGGGAGGTGTCCAGCCTTTTGAATACAGTACACAGCTA
TTTGTACTCATGGA

hide sequence

RefSeq Acc Id:

XM_039089359 ⟹ XP_038945287

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	12	11,230,864 - 11,244,898 (+)	NCBI

RefSeq Acc Id:

XM_039089360 ⟹ XP_038945288

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	12	11,235,492 - 11,244,898 (+)	NCBI

RefSeq Acc Id:

XM_039089361 ⟹ XP_038945289

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	12	11,234,145 - 11,244,898 (+)	NCBI

RefSeq Acc Id:

XM_039089362 ⟹ XP_038945290

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	12	11,230,864 - 11,244,898 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001013141	(Get FASTA)	NCBI Sequence Viewer
	XP_006248938	(Get FASTA)	NCBI Sequence Viewer
	XP_008767184	(Get FASTA)	NCBI Sequence Viewer
	XP_038945287	(Get FASTA)	NCBI Sequence Viewer
	XP_038945288	(Get FASTA)	NCBI Sequence Viewer
	XP_038945289	(Get FASTA)	NCBI Sequence Viewer
	XP_038945290	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH89831	(Get FASTA)	NCBI Sequence Viewer
	AAX73385	(Get FASTA)	NCBI Sequence Viewer
	EDL89673	(Get FASTA)	NCBI Sequence Viewer
	Q5FVR1	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

NP_001013141 ⟸ NM_001013123

- UniProtKB:

Q5FVR1 (UniProtKB/Swiss-Prot)

- Sequence:

show sequence

MDFLVLFSFYLAFLLICVIMICIFTKSQRLKAVVLGGAQVCARVTPQCFQRAVQTLLHQLFHTR
HPAFLALHLLLQGLVYAEYTYEVFSYCRELEFSLPCLLLPYVLLSVNLVFFTLTCSTNPGTITK
TNVLLLLQVYEFDEVMFPKNSRCSTCDLRKPARSKHCRVCDRCVHRFDHHCVWVNNCIGAWNTG
YFLIYLLTLTASAATIAILSAAFLLRLVAVSNLYQETYLDDLGRFQAVDTGFLIQHLFLAFPRI
IFLLGFVIVLSLLLAGYLCFALYLAATNQTTNEWYRGDWAWCQHWPLVAWSPSAEPQIHQNIYS
HGLWSNLQEVFIPATPSYKKKKR

hide sequence

RefSeq Acc Id:	XP_006248938 ⟸ XM_006248876
- Peptide Label:	isoform X1
- UniProtKB:	F1LQN6 (UniProtKB/TrEMBL)
- Sequence:	show sequence MDFLVLFSFYLAFLLICVIMICIFTKSQRLKAVVLGGAQVCARVTPQCFQRAVQTLLHQLFHTR HPAFLALHLLLQGLVYAEYTYEVFSYCRELEFSLPCLLLPYVLLSVNLVFFTLTCSTNPGTITK TNVSLLLQVYEFDEVMFPKNSRCSTCDLRKPARSKHCRVCDRCVHRFDHHCVWVNNCIGAWNTG YFLIYLLTLTASAATIAILSAAFLLRLVAVSNLYQETYLDDLGRFQAVDTGFLIQHLFLAFPRI IFLLGFVIVLSLLLAGYLCFALYLAATNQTTNEWYRGDWAWCQHWPLVAWSPSAEPQIHQNIYS HGLWSNLQEVFIPATPSYKKKKR hide sequence

RefSeq Acc Id:	XP_008767184 ⟸ XM_008768962
- Peptide Label:	isoform X1
- UniProtKB:	F1LQN6 (UniProtKB/TrEMBL)
- Sequence:	show sequence MDFLVLFSFYLAFLLICVIMICIFTKSQRLKAVVLGGAQVCARVTPQCFQRAVQTLLHQLFHTR HPAFLALHLLLQGLVYAEYTYEVFSYCRELEFSLPCLLLPYVLLSVNLVFFTLTCSTNPGTITK TNVSLLLQVYEFDEVMFPKNSRCSTCDLRKPARSKHCRVCDRCVHRFDHHCVWVNNCIGAWNTG YFLIYLLTLTASAATIAILSAAFLLRLVAVSNLYQETYLDDLGRFQAVDTGFLIQHLFLAFPRI IFLLGFVIVLSLLLAGYLCFALYLAATNQTTNEWYRGDWAWCQHWPLVAWSPSAEPQIHQNIYS HGLWSNLQEVFIPATPSYKKKKR hide sequence

RefSeq Acc Id:

ENSRNOP00000073588 ⟸ ENSRNOT00000084045

RefSeq Acc Id:	XP_038945287 ⟸ XM_039089359
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038945290 ⟸ XM_039089362
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038945289 ⟸ XM_039089361
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038945288 ⟸ XM_039089360
- Peptide Label:	isoform X2

Protein Domains

DHHC

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13698440

Promoter ID:

EPDNEW_R8965

Type:

initiation region

Name:

Zdhhc4_1

Description:

zinc finger, DHHC-type containing 4

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	12	13,284,539 - 13,284,599	EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)

ACI/EurMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

ACI/EurMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

ACI/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

BBDP/Wor (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

BN/SsN (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Buf/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

COP/CrCrl (MCW & UW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob) University of Wisconsin (Dr. James Shull)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Charles River Laboratories
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)

F344/NCrl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

F344/NRrrc (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

FHH/EurMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

FHH/EurMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

FHL/EurMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

FHL/EurMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

GH/OmrMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

GK/Ox (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LE/Stm (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LEW/Crl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LEW/NCrlBR (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LH/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LL/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LN/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

M520/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

MHS/Gib (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

MNS/Gib (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

MR/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

SBH/Ygl (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	SBH/Ygl sequenced by MCW

SBH/Ygl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SBN/Ygl (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	SBN/Ygl sequenced by MCW

SBN/Ygl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SHR/NHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SHRSP/Gcrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SR/JrHsd (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Harlan Laboratories
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

SR/JrHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SS/Jr (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SS/JrHsdMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

SS/JrHsdMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WAG/Rij (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/Gcrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

WKY/NCrl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/NHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WN/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1308389	AgrOrtholog
Ensembl Genes	ENSRNOG00000051699	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000073588	ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000084045	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7323958	IMAGE-MGC_LOAD
InterPro	Palmitoyltrfase_DHHC	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:304291	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:108810	IMAGE-MGC_LOAD
NCBI Gene	304291	ENTREZGENE
Pfam	DHHC	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Zdhhc4	PhenoGen
PROSITE	DHHC	UniProtKB/Swiss-Prot
UniProt	F1LQN6	ENTREZGENE, UniProtKB/TrEMBL
	Q5FVR1	ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary	Q2TGK2	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2019-11-11	Zdhhc4	zinc finger DHHC-type palmitoyltransferase 4	Zdhhc4	zinc finger, DHHC-type containing 4	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-11-17	Zdhhc4	zinc finger, DHHC-type containing 4	Zdhhc4	zinc finger, DHHC domain containing 4	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-12-06	Zdhhc4	zinc finger, DHHC domain containing 4	Zdhhc4_predicted	zinc finger, DHHC domain containing 4 (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-12	Zdhhc4_predicted	zinc finger, DHHC domain containing 4 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)