Retn (resistin) - Rat Genome Database
Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Retn (resistin) Rattus norvegicus
Analyze
Symbol: Retn
Name: resistin
RGD ID: 628781
Description: Predicted to have hormone activity. Involved in several processes, including positive regulation of cell communication; positive regulation of smooth muscle cell migration; and positive regulation of smooth muscle cell proliferation. Localizes to extracellular space and nucleus. Used to study colitis. Biomarker of non-alcoholic fatty liver disease. Human ortholog(s) of this gene implicated in hypertension; hypertrophic cardiomyopathy; obesity; and type 2 diabetes mellitus. Orthologous to human RETN (resistin); INTERACTS WITH (S)-nicotine; 1,2-dimethylhydrazine; 1-methylnicotinamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2121,710,881 - 1,712,621 (+)NCBI
Rnor_6.0 Ensembl122,201,891 - 2,204,249 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0122,201,909 - 2,203,649 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0124,364,007 - 4,365,747 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4122,499,630 - 2,501,370 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1122,499,629 - 2,501,370 (-)NCBI
Celera123,566,836 - 3,568,576 (+)NCBICelera
Cytogenetic Map12p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(R)-mevalonic acid  (ISO)
(S)-nicotine  (EXP)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (EXP)
1-methylnicotinamide  (EXP)
17beta-estradiol  (EXP,ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2-trans,6-trans,10-trans-geranylgeranyl diphosphate  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3,7-dihydropurine-6-thione  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
9-cis-retinoic acid  (ISO)
aflatoxin B1  (ISO)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (ISO)
all-trans-retinol  (ISO)
Aloe emodin  (ISO)
amlodipine  (ISO)
ammonium chloride  (EXP)
amphetamine  (EXP)
arachidonic acid  (ISO)
arsenite(3-)  (ISO)
Aurothioglucose  (ISO)
benzo[a]pyrene  (ISO)
benzo[b]fluoranthene  (ISO)
benzofurans  (ISO)
bis(2-chloroethyl) sulfide  (EXP)
bisphenol A  (EXP,ISO)
cadmium dichloride  (EXP,ISO)
capsaicin  (EXP)
carbon nanotube  (ISO)
choline  (ISO)
corticosterone  (ISO)
D-glucose  (ISO)
DDE  (ISO)
deoxycholic acid  (ISO)
dexamethasone  (ISO)
disodium cromoglycate  (ISO)
folic acid  (ISO)
fructose  (EXP)
fucoxanthin  (ISO)
fulvestrant  (ISO)
genistein  (ISO)
glucose  (ISO)
glycine  (ISO)
hesperetin  (ISO)
hydrazine  (ISO)
hydrazines  (ISO)
Indeno[1,2,3-cd]pyrene  (ISO)
iron atom  (ISO)
iron(0)  (ISO)
L-methionine  (ISO)
letrozole  (EXP)
lipopolysaccharide  (ISO)
mercaptopurine  (EXP)
metformin  (EXP)
monosodium L-glutamate  (ISO)
naproxen  (EXP,ISO)
nicotine  (EXP)
nicotinic acid  (ISO)
nitric oxide  (EXP,ISO)
nitroprusside  (ISO)
NMN zwitterion  (ISO)
Nonylphenol  (ISO)
oxybenzone  (EXP)
ozone  (ISO)
phenethyl caffeate  (ISO)
phosphatidylcholine  (ISO)
picolinic acid  (ISO)
pioglitazone  (ISO)
potassium bromate  (EXP)
progesterone  (EXP,ISO)
prostaglandin E2  (ISO)
protein kinase inhibitor  (ISO)
purine-6-thiol  (EXP)
resveratrol  (EXP,ISO)
SB 203580  (ISO)
simvastatin  (ISO)
stilben-4-ol  (ISO)
streptozocin  (EXP)
sulforaphane  (ISO)
sumatriptan  (EXP)
testosterone  (ISO)
titanium dioxide  (ISO)
tributylstannane  (ISO)
vinclozolin  (EXP)
XL147  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
1. Baker JF, etal., J Rheumatol. 2011 Nov;38(11):2369-75. doi: 10.3899/jrheum.110237. Epub 2011 Sep 1.
2. Baldasseroni S, etal., J Cardiovasc Med (Hagerstown). 2013 Feb;14(2):150-7. doi: 10.2459/JCM.0b013e32834eec93.
3. Chi S, etal., Mol Cell Biochem. 2009 Apr 21.
4. Chung W, etal., J Korean Med Sci. 2012 Apr;27(4):377-81. doi: 10.3346/jkms.2012.27.4.377. Epub 2012 Mar 21.
5. Cifani C, etal., Acta Physiol (Oxf). 2009 Aug;196(4):395-400. doi: 10.1111/j.1748-1716.2008.01949.x. Epub 2008 Dec 16.
6. Clemente TR, etal., Scand J Gastroenterol. 2012 Sep;8-9(47):943-50. doi: 10.3109/00365521.2012.688213. Epub 2012 May 28.
7. Del Arco A, etal., FEBS Lett. 2003 Dec 4;555(2):243-9.
8. Delhanty PJ, etal., Endocrinology 2002 Jun;143(6):2445-8.
9. Diez JJ, etal., Clin Endocrinol (Oxf). 2005 Feb;62(2):242-9.
10. Dominguez Coello S, etal., Diabetes Res Clin Pract. 2008 Nov;82(2):256-61. Epub 2008 Sep 11.
11. Fernandez CM, etal., Metabolism. 2009 Feb;58(2):204-11. doi: 10.1016/j.metabol.2008.09.014.
12. Fraser DD, etal., Crit Care Explor. 2020 Jun 22;2(6):e0144. doi: 10.1097/CCE.0000000000000144. eCollection 2020 Jun.
13. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
14. GOA data from the GO Consortium
15. Gong H, etal., Eur J Endocrinol. 2004 Jun;150(6):885-92.
16. Ho KJ, etal., J Surg Res. 2013 Jan;179(1):175-82. doi: 10.1016/j.jss.2012.08.043. Epub 2012 Sep 6.
17. Hussain S, etal., Transl Res. 2010 Mar;155(3):142-7. doi: 10.1016/j.trsl.2009.10.002. Epub 2009 Nov 4.
18. Koch A, etal., Crit Care. 2009;13(3):R95. doi: 10.1186/cc7925. Epub 2009 Jun 19.
19. Kosari S, etal., J Neuroendocrinol. 2012 Nov;24(11):1432-9. doi: 10.1111/j.1365-2826.2012.02352.x.
20. Kreier F, etal., J Clin Invest 2002 Nov;110(9):1243-50.
21. Kuzmicki M, etal., Gynecol Endocrinol. 2009 Apr;25(4):258-63.2: id: 38815448 Error occurred: The following PMID is not available: -13: id: 58220487 Error occurred: The following PMID is not available: -14: id: 77618179 Error occurred: The following PMID is not available: -1
22. Lee SH, etal., Coron Artery Dis. 2009 Jan;20(1):33-9. doi: 10.1097/MCA.0b013e328318ecb0.
23. Lu SC, etal., FEBS Lett 2002 Oct 23;530(1-3):158-62.
24. Maillard V, etal., Reproduction. 2011 Apr;141(4):467-79. doi: 10.1530/REP-10-0419. Epub 2011 Jan 14.
25. Makino H, etal., Endocr J. 2009 Sep 9.
26. Malyszko J, etal., Transplant Proc. 2006 Dec;38(10):3434-6.
27. Mazaki-Tovi S, etal., Am J Reprod Immunol. 2010 May;63(5):358-69. doi: 10.1111/j.1600-0897.2010.00809.x. Epub 2010 Feb 18.
28. MGD data from the GO Consortium
29. Nehus E, etal., J Pediatr. 2012 Aug;161(2):276-80. doi: 10.1016/j.jpeds.2012.01.055. Epub 2012 Mar 14.
30. Norata GD, etal., J Intern Med. 2007 Jul;262(1):104-12.
31. OMIM Disease Annotation Pipeline
32. Online Mendelian Inheritance in Man, OMIM (TM).
33. Osawa H, etal., Biochem Biophys Res Commun. 2007 Apr 6;355(2):342-6. Epub 2007 Feb 5.
34. Rasic D, etal., Vojnosanit Pregl. 2010 Dec;67(12):965-8.
35. RGD automated data pipeline
36. RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
37. RGD automated import pipeline for gene-chemical interactions
38. Roth CL, etal., Hepatology. 2012 Apr;55(4):1103-11. doi: 10.1002/hep.24737. Epub 2012 Feb 15.
39. Sadashiv, etal., World J Diabetes. 2012 Jul 15;3(7):135-41. doi: 10.4239/wjd.v3.i7.135.
40. Schaffler A, etal., Horm Metab Res. 2004 Oct;36(10):702-7.
41. Shyu KG, etal., Clin Sci (Lond). 2011 Feb;120(3):121-9. doi: 10.1042/CS20100226.
42. Smalley DM, etal., J Proteome Res. 2008 May;7(5):2088-96. doi: 10.1021/pr700775x. Epub 2008 Mar 29.
43. Steppan CM, etal., Nature. 2001 Jan 18;409(6818):307-12.
44. Suriyaprom K, etal., J Clin Biochem Nutr. 2009 Jan;44(1):104-10. Epub 2008 Dec 27.
45. Tan MS, etal., J Clin Endocrinol Metab. 2003 Mar;88(3):1258-63.
46. Tsioufis C, etal., Am J Hypertens. 2010 Jun;23(6):681-6. doi: 10.1038/ajh.2010.34. Epub 2010 Mar 4.
47. Tsukahara T, etal., Diabetes Res Clin Pract. 2009 May;84(2):179-86. Epub 2009 Mar 6.
48. Wang BW, etal., Clin Sci (Lond). 2009 Oct 26;118(3):221-30.
49. Wang XH, etal., Zhonghua Yi Xue Za Zhi. 2007 Jul 3;87(25):1755-7.
50. Yang G, etal., Metabolism. 2005 Sep;54(9):1142-6.
51. Zhao J, etal., Scand J Gastroenterol. 2010 Nov;45(11):1360-71. doi: 10.3109/00365521.2010.497938. Epub 2010 Jun 21.
Additional References at PubMed
PMID:11209052   PMID:12429872   PMID:12477932   PMID:12634438   PMID:12660872   PMID:12885401   PMID:12944409   PMID:14577616   PMID:14592417   PMID:15226398   PMID:15526156   PMID:15642357  
PMID:15737463   PMID:16154759   PMID:16338222   PMID:16404608   PMID:16934751   PMID:17063326   PMID:17241525   PMID:17418807   PMID:17557231   PMID:17573461   PMID:17611902   PMID:17693256  
PMID:17890220   PMID:17922337   PMID:17991727   PMID:18063850   PMID:18176969   PMID:18178314   PMID:18239591   PMID:18499762   PMID:18597775   PMID:19008713   PMID:19041881   PMID:19589870  
PMID:19785957   PMID:20627112   PMID:21478152   PMID:21557150   PMID:21586564   PMID:22372349   PMID:22645452   PMID:22855443   PMID:23376485   PMID:23533145   PMID:23765438   PMID:23867317  
PMID:23901222   PMID:24610624   PMID:25065280   PMID:25217974   PMID:26383117   PMID:26811539   PMID:26846568   PMID:26909974   PMID:27797297   PMID:27959400   PMID:28877872   PMID:29500410  
PMID:31053755   PMID:31085594  


Genomics

Comparative Map Data
Retn
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2121,710,881 - 1,712,621 (+)NCBI
Rnor_6.0 Ensembl122,201,891 - 2,204,249 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0122,201,909 - 2,203,649 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0124,364,007 - 4,365,747 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4122,499,630 - 2,501,370 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1122,499,629 - 2,501,370 (-)NCBI
Celera123,566,836 - 3,568,576 (+)NCBICelera
Cytogenetic Map12p12NCBI
RETN
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl197,669,049 - 7,670,455 (+)EnsemblGRCh38hg38GRCh38
GRCh38197,669,049 - 7,670,455 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37197,733,935 - 7,735,341 (+)NCBIGRCh37GRCh37hg19GRCh37
GRCh37197,733,972 - 7,735,340 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36197,639,972 - 7,641,340 (+)NCBINCBI36hg18NCBI36
Build 34197,639,971 - 7,641,340NCBI
Celera197,605,160 - 7,606,528 (+)NCBI
Cytogenetic Map19p13.2NCBI
HuRef197,403,771 - 7,405,139 (+)NCBIHuRef
CHM1_1197,733,708 - 7,735,063 (+)NCBICHM1_1
Retn
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3983,705,770 - 3,709,818 (+)NCBIGRCm39mm39
GRCm3883,655,770 - 3,659,818 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl83,655,770 - 3,660,110 (+)EnsemblGRCm38mm10GRCm38
MGSCv3783,655,789 - 3,658,096 (+)NCBIGRCm37mm9NCBIm37
MGSCv3683,655,789 - 3,658,096 (+)NCBImm8
Celera83,886,118 - 3,888,425 (+)NCBICelera
Cytogenetic Map8A1.1NCBI
cM Map81.92NCBI
Retn
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555631,607,814 - 1,609,273 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555631,607,814 - 1,609,273 (-)NCBIChiLan1.0ChiLan1.0
RETN
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1197,812,942 - 7,814,909 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl197,812,942 - 7,814,909 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0196,958,536 - 6,960,032 (+)NCBIMhudiblu_PPA_v0panPan3
RETN
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl2052,434,271 - 52,435,624 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.12052,434,148 - 52,435,627 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Retn
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049365884,705,295 - 4,706,653 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RETN
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl271,484,169 - 71,485,616 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1271,484,164 - 71,485,577 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2271,871,237 - 71,872,650 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap2q21NCBI
RETN
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.167,154,771 - 7,156,459 (+)NCBI
ChlSab1.1 Ensembl67,155,337 - 7,156,505 (+)Ensembl
Retn
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624828735,562 - 737,166 (+)NCBI

Position Markers
RH127742  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0122,203,839 - 2,204,057NCBIRnor6.0
Rnor_5.0124,365,937 - 4,366,155UniSTSRnor5.0
RGSC_v3.4122,499,222 - 2,499,440UniSTSRGSC3.4
Celera123,568,766 - 3,568,984UniSTS
Cytogenetic Map12p12UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300174Bw15Body weight QTL 152.93body mass (VT:0001259)body weight loss (CMO:0001399)12111765163Rat
2312418Kidm41Kidney mass QTL 413.70.0001kidney mass (VT:0002707)single kidney wet weight to body weight ratio (CMO:0000622)12122650917Rat
10450854Stl34Serum triglyceride level QTL 343.50.05blood LDL triglyceride amount (VT:0010699)blood lipoprotein triglyceride level (CMO:0002685)12122853017Rat
10755457Coatc14Coat color QTL 140.01759coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)12123035872Rat
6893681Bw109Body weight QTL 1092.30.004body mass (VT:0001259)body weight (CMO:0000012)12123758197Rat
1581516Cm56Cardiac mass QTL 564.20.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)12130749723Rat
1598855Bp294Blood pressure QTL 2943.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)12136919844Rat
7387292Kidm42Kidney mass QTL 423.030.0004kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)12138334225Rat
9590086Insglur6Insulin/glucose ratio QTL 618.970.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)1215081045150810Rat
9590147Scort7Serum corticosterone level QTL 713.610.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)1215081045150810Rat
7411545Bw128Body weight QTL 1285.20.001body mass (VT:0001259)body weight gain (CMO:0000420)1215081045150810Rat
7411586Foco5Food consumption QTL 55.40.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)1215081045150810Rat
7411660Foco28Food consumption QTL 2810.90.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)1215081045150810Rat
7411595Foco9Food consumption QTL 940.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)1215081045150810Rat
8694179Bw150Body weight QTL 1502.90.001body mass (VT:0001259)body weight gain (CMO:0000420)1215081045150810Rat
2303575Insul14Insulin level QTL 144blood insulin amount (VT:0001560)blood insulin level (CMO:0000349)1249257845492578Rat
7243862Mcs30Mammary carcinoma susceptibility QTL 308.62mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)12125813910257059Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:131
Count of miRNA genes:108
Interacting mature miRNAs:117
Transcripts:ENSRNOT00000001325
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 13 2 4 2 1 6 2
Low 3 12 21 16 7 16 7 10 19 3 9 7
Below cutoff 6 11 11 8 11 1 1 10 10 14 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000001325   ⟹   ENSRNOP00000001325
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl122,201,949 - 2,203,614 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000091197   ⟹   ENSRNOP00000073327
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl122,201,891 - 2,204,249 (+)Ensembl
RefSeq Acc Id: NM_144741   ⟹   NP_653342
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2121,710,881 - 1,712,621 (+)NCBI
Rnor_6.0122,201,909 - 2,203,649 (+)NCBI
Rnor_5.0124,364,007 - 4,365,747 (+)NCBI
RGSC_v3.4122,499,630 - 2,501,370 (-)RGD
Celera123,566,836 - 3,568,576 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_653342 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAM46115 (Get FASTA)   NCBI Sequence Viewer  
  BAC21195 (Get FASTA)   NCBI Sequence Viewer  
  BAC56585 (Get FASTA)   NCBI Sequence Viewer  
  CAD88269 (Get FASTA)   NCBI Sequence Viewer  
  EDL74954 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_653342   ⟸   NM_144741
- Peptide Label: precursor
- UniProtKB: Q8K4J7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000073327   ⟸   ENSRNOT00000091197
RefSeq Acc Id: ENSRNOP00000001325   ⟸   ENSRNOT00000001325

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698374
Promoter ID:EPDNEW_R8899
Type:single initiation site
Name:Retn_1
Description:resistin
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0122,201,936 - 2,201,996EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:628781 AgrOrtholog
Ensembl Genes ENSRNOG00000001001 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000001325 UniProtKB/TrEMBL
  ENSRNOP00000073327 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000001325 UniProtKB/TrEMBL
  ENSRNOT00000091197 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 3.30.1660.20 UniProtKB/TrEMBL
InterPro Resistin UniProtKB/TrEMBL
  Resistin-like_sf UniProtKB/TrEMBL
KEGG Report rno:246250 UniProtKB/TrEMBL
NCBI Gene 246250 ENTREZGENE
PANTHER Resistin UniProtKB/TrEMBL
Pfam Resistin UniProtKB/TrEMBL
PhenoGen Retn PhenoGen
Superfamily-SCOP Resistin UniProtKB/TrEMBL
UniProt Q70Q42_RAT UniProtKB/TrEMBL
  Q8K4J7 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-09-10 Retn  resistin      Symbol and Name status set to approved 1299863 APPROVED
2003-02-27 Retn  resistin      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_expression expressed in white adipose tissue 633881
gene_expression expressed in the adipose tissues 628347
gene_expression expression is induced by growth hormone in the spontaneous dwarf strain 633881
gene_regulation expression of mRNA is decreased by a fat pad specific vagotomy 628347