Arpc1a (actin related protein 2/3 complex, subunit 1A) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Arpc1a (actin related protein 2/3 complex, subunit 1A) Rattus norvegicus
Analyze
Symbol: Arpc1a
Name: actin related protein 2/3 complex, subunit 1A
RGD ID: 620834
Description: Predicted to enable actin filament binding activity. Predicted to be involved in Arp2/3 complex-mediated actin nucleation. Predicted to be located in muscle cell projection membrane; nucleus; and site of double-strand break. Predicted to be part of Arp2/3 protein complex. Predicted to be active in glutamatergic synapse. Human ortholog(s) of this gene implicated in pancreatic cancer. Orthologous to human ARPC1A (actin related protein 2/3 complex subunit 1A); PARTICIPATES IN insulin responsive facilitative sugar transporter mediated glucose transport pathway; Rab family mediated signaling pathway; Fc gamma receptor mediated signaling pathway; INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: actin-related protein 2/3 complex subunit 1A; LOC100360680; suppressor of profilin/p41 of actin-related complex 2/3
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81214,616,245 - 14,639,052 (-)NCBIGRCr8
mRatBN7.2129,502,496 - 9,525,304 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl129,502,501 - 9,525,330 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1210,307,262 - 10,330,326 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01210,930,465 - 10,953,529 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0129,953,893 - 9,976,958 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01211,272,609 - 11,294,084 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1211,272,609 - 11,294,058 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01213,341,711 - 13,363,473 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.1129,846,583 - 9,863,837 (-)NCBI
Celera1211,307,305 - 11,329,866 (-)NCBICelera
Cytogenetic Map12p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Arp2/3- and cofilin-coordinated actin dynamics is required for insulin-mediated GLUT4 translocation to the surface of muscle cells. Chiu TT, etal., Mol Biol Cell. 2010 Oct 15;21(20):3529-39. doi: 10.1091/mbc.E10-04-0316. Epub 2010 Aug 25.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Characterization of the 7q21-q22 amplicon identifies ARPC1A, a subunit of the Arp2/3 complex, as a regulator of cell migration and invasion in pancreatic cancer. Laurila E, etal., Genes Chromosomes Cancer. 2009 Apr;48(4):330-9.
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
6. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
7. Mitochondrial dysfunction in schizophrenia: evidence for compromised brain metabolism and oxidative stress. Prabakaran S, etal., Mol Psychiatry. 2004 Jul;9(7):684-97, 643.
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:8889548   PMID:12477932   PMID:17086175   PMID:19056867   PMID:22553210   PMID:22871113   PMID:23376485  


Genomics

Comparative Map Data
Arpc1a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81214,616,245 - 14,639,052 (-)NCBIGRCr8
mRatBN7.2129,502,496 - 9,525,304 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl129,502,501 - 9,525,330 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1210,307,262 - 10,330,326 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01210,930,465 - 10,953,529 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0129,953,893 - 9,976,958 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01211,272,609 - 11,294,084 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1211,272,609 - 11,294,058 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01213,341,711 - 13,363,473 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.1129,846,583 - 9,863,837 (-)NCBI
Celera1211,307,305 - 11,329,866 (-)NCBICelera
Cytogenetic Map12p11NCBI
ARPC1A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38799,325,898 - 99,366,262 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl799,325,898 - 99,366,262 (+)EnsemblGRCh38hg38GRCh38
GRCh37798,923,521 - 98,963,885 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36798,761,446 - 98,801,821 (+)NCBINCBI36Build 36hg18NCBI36
Build 34798,568,160 - 98,608,538NCBI
Celera793,657,670 - 93,698,057 (+)NCBICelera
Cytogenetic Map7q22.1NCBI
HuRef793,559,314 - 93,599,623 (+)NCBIHuRef
CHM1_1798,853,571 - 98,893,965 (+)NCBICHM1_1
T2T-CHM13v2.07100,564,792 - 100,605,160 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2798,283,446 - 98,323,834 (+)NCBI
Arpc1a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395145,020,679 - 145,045,566 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5145,020,640 - 145,045,571 (+)EnsemblGRCm39 Ensembl
GRCm385145,083,869 - 145,108,756 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5145,083,830 - 145,108,761 (+)EnsemblGRCm38mm10GRCm38
MGSCv375145,844,738 - 145,869,625 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365145,337,396 - 145,362,283 (+)NCBIMGSCv36mm8
Celera5142,075,658 - 142,100,687 (+)NCBICelera
Cytogenetic Map5G2NCBI
cM Map585.0NCBI
Arpc1a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546015,023,221 - 15,051,115 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495546015,022,663 - 15,050,955 (+)NCBIChiLan1.0ChiLan1.0
ARPC1A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26117,183,767 - 117,223,936 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan17165,448,403 - 165,488,570 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0791,299,559 - 91,339,729 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17104,801,399 - 104,841,590 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7104,801,399 - 104,841,590 (+)Ensemblpanpan1.1panPan2
ARPC1A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1610,212,203 - 10,245,112 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl610,212,494 - 10,245,073 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha611,838,931 - 11,871,811 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0610,212,409 - 10,245,315 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl610,212,412 - 10,245,312 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1610,082,332 - 10,115,224 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0610,060,836 - 10,093,722 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0610,294,657 - 10,327,563 (-)NCBIUU_Cfam_GSD_1.0
Arpc1a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344138,300,216 - 138,334,198 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367501,611,030 - 1,646,608 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367501,611,082 - 1,645,045 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ARPC1A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl36,296,278 - 6,324,524 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.136,296,257 - 6,324,526 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.236,434,509 - 6,462,700 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ARPC1A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12813,793,196 - 13,833,254 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2813,764,945 - 13,825,815 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660702,470,717 - 2,509,959 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Arpc1a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474032,771,885 - 32,805,516 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474032,771,870 - 32,801,047 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Arpc1a
220 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:109
Count of miRNA genes:93
Interacting mature miRNAs:99
Transcripts:ENSRNOT00000001319, ENSRNOT00000066198
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2312418Kidm41Kidney mass QTL 413.70.0001kidney mass (VT:0002707)single kidney wet weight to body weight ratio (CMO:0000622)12119611090Rat
8552964Pigfal17Plasma insulin-like growth factor 1 level QTL 173.5blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449546669029Rat
7411641Foco19Food consumption QTL 1927.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12556449546669029Rat
1331739Hrtrt14Heart rate QTL 143.56232heart pumping trait (VT:2000009)heart rate (CMO:0000002)12931821612829686Rat
9590147Scort7Serum corticosterone level QTL 713.610.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)12142110980Rat
8552912Pigfal6Plasma insulin-like growth factor 1 level QTL 65blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449846669029Rat
10059594Kidm46Kidney mass QTL 463.790.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)12610757946669029Rat
61331Eau2Experimental allergic uveoretinitis QTL 20.0005uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)12852542328064601Rat
1581516Cm56Cardiac mass QTL 564.20.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)12129333307Rat
9590086Insglur6Insulin/glucose ratio QTL 618.970.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)12142110980Rat
8552918Pigfal7Plasma insulin-like growth factor 1 level QTL 7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449546669029Rat
6893681Bw109Body weight QTL 1092.30.004body mass (VT:0001259)body weight (CMO:0000012)12123297788Rat
1302792Scl21Serum cholesterol level QTL 213.80.0011blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)12719673046669029Rat
1598855Bp294Blood pressure QTL 2943.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)12134851688Rat
1600391Edcs2Endometrial carcinoma susceptibility QTL23.50.01uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)12683319017870186Rat
10755457Coatc14Coat color QTL 140.01759coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)12122591684Rat
724526Uae3Urinary albumin excretion QTL 34.90.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)12390696910373166Rat
634351Apr5Acute phase response QTL 56.7blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)12144503507Rat
8694179Bw150Body weight QTL 1502.90.001body mass (VT:0001259)body weight gain (CMO:0000420)12142110980Rat
634350Apr4Acute phase response QTL 46orosomucoid 1 amount (VT:0010541)plasma orosomucoid 1 level (CMO:0001467)12117200546172005Rat
7411545Bw128Body weight QTL 1285.20.001body mass (VT:0001259)body weight gain (CMO:0000420)12142110980Rat
7411547Bw129Body weight QTL 1290.001body mass (VT:0001259)body weight gain (CMO:0000420)6556449546669029Rat
1300157Rf21Renal function QTL 214.4renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)12931821632103380Rat
737979Pia22Pristane induced arthritis QTL 2253.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)12144465750Rat
7411586Foco5Food consumption QTL 55.40.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12142110980Rat
2303575Insul14Insulin level QTL 144blood insulin amount (VT:0001560)blood insulin level (CMO:0000349)12142450532Rat
7411588Foco6Food consumption QTL 60.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12556449546669029Rat
2302042Pia38Pristane induced arthritis QTL 383.50.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)12144503507Rat
7411595Foco9Food consumption QTL 940.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12142110980Rat
7411597Foco10Food consumption QTL 100.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12556449546669029Rat
2293086Iddm30Insulin dependent diabetes mellitus QTL 303.82blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)12844949028302290Rat
7411660Foco28Food consumption QTL 2810.90.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12142110980Rat

Markers in Region
D12Got101  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2129,526,882 - 9,527,086 (+)MAPPERmRatBN7.2
Rnor_6.01211,295,663 - 11,295,866NCBIRnor6.0
Rnor_5.01213,365,052 - 13,365,255UniSTSRnor5.0
RGSC_v3.4129,840,695 - 9,840,898RGDRGSC3.4
RGSC_v3.4129,840,696 - 9,840,899UniSTSRGSC3.4
RGSC_v3.1129,870,623 - 9,870,826RGD
Celera1211,331,436 - 11,331,639UniSTS
RH 3.4 Map12102.3UniSTS
RH 3.4 Map12102.3RGD
RH 2.0 Map1296.4RGD
Cytogenetic Map12p11UniSTS
RH128130  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2129,502,533 - 9,502,749 (+)MAPPERmRatBN7.2
Rnor_6.01211,272,647 - 11,272,862NCBIRnor6.0
Rnor_5.01213,341,749 - 13,341,964UniSTSRnor5.0
Celera1211,307,343 - 11,307,558UniSTS
RH 3.4 Map12121.4UniSTS
Cytogenetic Map12p11UniSTS
RH125677  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2129,502,598 - 9,502,761 (+)MAPPERmRatBN7.2
Rnor_6.01211,272,712 - 11,272,874NCBIRnor6.0
Rnor_5.01213,341,814 - 13,341,976UniSTSRnor5.0
Celera1211,307,408 - 11,307,570UniSTS
Cytogenetic Map12p11UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000001319   ⟹   ENSRNOP00000001319
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl129,504,765 - 9,525,309 (-)Ensembl
Rnor_6.0 Ensembl1211,277,338 - 11,294,058 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000076021   ⟹   ENSRNOP00000068218
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl129,502,501 - 9,525,308 (-)Ensembl
Rnor_6.0 Ensembl1211,272,609 - 11,272,997 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000106194   ⟹   ENSRNOP00000088601
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl129,502,564 - 9,516,775 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000117369   ⟹   ENSRNOP00000077939
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl129,502,502 - 9,525,330 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000119670   ⟹   ENSRNOP00000086469
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl129,511,287 - 9,525,330 (-)Ensembl
RefSeq Acc Id: NM_031146   ⟹   NP_112408
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81214,616,245 - 14,639,052 (-)NCBI
mRatBN7.2129,502,496 - 9,525,304 (-)NCBI
Rnor_6.01211,272,609 - 11,294,084 (-)NCBI
Rnor_5.01213,341,711 - 13,363,473 (-)NCBI
Celera1211,307,305 - 11,329,866 (-)RGD
Sequence:
RefSeq Acc Id: NP_112408   ⟸   NM_031146
- UniProtKB: Q99PD4 (UniProtKB/Swiss-Prot),   A6K1G3 (UniProtKB/TrEMBL),   A0A8I5Y805 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000001319   ⟸   ENSRNOT00000001319
Ensembl Acc Id: ENSRNOP00000068218   ⟸   ENSRNOT00000076021
Ensembl Acc Id: ENSRNOP00000086469   ⟸   ENSRNOT00000119670
Ensembl Acc Id: ENSRNOP00000077939   ⟸   ENSRNOT00000117369
Ensembl Acc Id: ENSRNOP00000088601   ⟸   ENSRNOT00000106194

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q99PD4-F1-model_v2 AlphaFold Q99PD4 1-370 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698420
Promoter ID:EPDNEW_R8944
Type:initiation region
Name:Arpc1a_1
Description:actin related protein 2/3 complex, subunit 1A
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01211,294,058 - 11,294,118EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620834 AgrOrtholog
BioCyc Gene G2FUF-20054 BioCyc
Ensembl Genes ENSRNOG00000000996 Ensembl, UniProtKB/TrEMBL
  ENSRNOG00055011868 UniProtKB/Swiss-Prot
  ENSRNOG00060023992 UniProtKB/Swiss-Prot
  ENSRNOG00065006018 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000001319.8 UniProtKB/TrEMBL
  ENSRNOT00000076021.2 UniProtKB/TrEMBL
  ENSRNOT00000106194.1 UniProtKB/TrEMBL
  ENSRNOT00000117369.1 UniProtKB/TrEMBL
  ENSRNOT00000119670.1 UniProtKB/TrEMBL
  ENSRNOT00055020208 UniProtKB/Swiss-Prot
  ENSRNOT00060041948 UniProtKB/Swiss-Prot
  ENSRNOT00065009128 UniProtKB/Swiss-Prot
Gene3D-CATH 2.130.10.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:6921520 IMAGE-MGC_LOAD
InterPro ARPC1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40_repeat UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40_repeat_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:81824 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:72782 IMAGE-MGC_LOAD
NCBI Gene 81824 ENTREZGENE
PANTHER PTHR10709 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR10709:SF11 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam WD40 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Arpc1a PhenoGen
PIRSF ARP2/3_su1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE WD_REPEATS_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD_REPEATS_REGION UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000000996 RatGTEx
  ENSRNOG00055011868 RatGTEx
  ENSRNOG00060023992 RatGTEx
  ENSRNOG00065006018 RatGTEx
SMART WD40 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF50978 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A096MJQ1_RAT UniProtKB/TrEMBL
  A0A8I5Y805 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A290_RAT UniProtKB/TrEMBL
  A0A8I6AB38_RAT UniProtKB/TrEMBL
  A6K1G3 ENTREZGENE, UniProtKB/TrEMBL
  ARC1A_RAT UniProtKB/Swiss-Prot
  D3ZXP7_RAT UniProtKB/TrEMBL
  Q6PCU9_RAT UniProtKB/TrEMBL
  Q99PD4 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-04-17 Arpc1a  actin related protein 2/3 complex, subunit 1A  LOC100360680  actin related protein 2/3 complex, subunit 1A  Data merged from RGD:2321677 737654 PROVISIONAL
2010-05-06 LOC100360680  actin related protein 2/3 complex, subunit 1A      Symbol and Name status set to provisional 70820 PROVISIONAL
2005-01-20 Arpc1a  actin related protein 2/3 complex, subunit 1A    suppressor of profilin/p41 of actin-related complex 2/3  Name updated 1299863 APPROVED
2002-08-07 Arpc1a  suppressor of profilin/p41 of actin-related complex 2/3      Symbol and Name status set to provisional 70820 PROVISIONAL