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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Rilpl2 | Rat | 1,2-dimethylhydrazine | increases expression | ISO | Rilpl2 (Mus musculus) | 6480464 | 1,2-Dimethylhydrazine results in increased expression of RILPL2 mRNA | CTD | PMID:22206623 | Rilpl2 | Rat | 1,2-dimethylhydrazine | multiple interactions | ISO | Rilpl2 (Mus musculus) | 6480464 | Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of RILPL2 mRNA] | CTD | PMID:22206623 | Rilpl2 | Rat | 17beta-estradiol | affects expression | ISO | RILPL2 (Homo sapiens) | 6480464 | Estradiol affects the expression of RILPL2 mRNA | CTD | PMID:22574217 | Rilpl2 | Rat | 17beta-estradiol | decreases expression | ISO | RILPL2 (Homo sapiens) | 6480464 | Estradiol results in decreased expression of RILPL2 mRNA | CTD | PMID:31614463 | Rilpl2 | Rat | 17beta-estradiol | multiple interactions | ISO | RILPL2 (Homo sapiens) | 6480464 | [Estradiol co-treated with Norethindrone Acetate] results in increased expression of RILPL2 mRNA; [Estradiol co-treated with more ... | CTD | PMID:20660070|PMID:22217510 | Rilpl2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Rilpl2 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of RILPL2 mRNA | CTD | PMID:21570461 | Rilpl2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of RILPL2 mRNA | CTD | PMID:34747641 | Rilpl2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of RILPL2 mRNA | CTD | PMID:32109520 | Rilpl2 | Rat | 2,4-dibromophenyl 2,4,5-tribromophenyl ether | affects expression | ISO | Rilpl2 (Mus musculus) | 6480464 | 2,2',4,4',5-brominated diphenyl ether affects the expression of RILPL2 mRNA | CTD | PMID:38648751 | Rilpl2 | Rat | 4,4'-diaminodiphenylmethane | decreases expression | ISO | Rilpl2 (Mus musculus) | 6480464 | 4,4'-diaminodiphenylmethane results in decreased expression of RILPL2 mRNA | CTD | PMID:18648102 | Rilpl2 | Rat | 4,4'-sulfonyldiphenol | decreases expression | ISO | Rilpl2 (Mus musculus) | 6480464 | bisphenol S results in decreased expression of RILPL2 mRNA | CTD | PMID:39298647 | Rilpl2 | Rat | 4,4'-sulfonyldiphenol | increases expression | ISO | Rilpl2 (Mus musculus) | 6480464 | bisphenol S results in increased expression of RILPL2 mRNA | CTD | PMID:33297965 | Rilpl2 | Rat | actinomycin D | multiple interactions | ISO | RILPL2 (Homo sapiens) | 6480464 | [Dactinomycin co-treated with nutlin 3] results in increased expression of RILPL2 mRNA | CTD | PMID:38460933 | Rilpl2 | Rat | aflatoxin B1 | increases expression | ISO | Rilpl2 (Mus musculus) | 6480464 | Aflatoxin B1 results in increased expression of RILPL2 mRNA | CTD | PMID:19770486 | Rilpl2 | Rat | Aflatoxin B2 alpha | decreases methylation | ISO | RILPL2 (Homo sapiens) | 6480464 | aflatoxin B2 results in decreased methylation of RILPL2 intron | CTD | PMID:30157460 | Rilpl2 | Rat | all-trans-retinoic acid | increases expression | ISO | RILPL2 (Homo sapiens) | 6480464 | Tretinoin results in increased expression of RILPL2 mRNA | CTD | PMID:33167477 | Rilpl2 | Rat | aristolochic acid A | increases expression | ISO | RILPL2 (Homo sapiens) | 6480464 | aristolochic acid I results in increased expression of RILPL2 mRNA | CTD | PMID:33212167 | Rilpl2 | Rat | benzo[a]pyrene | increases expression | EXP | | 6480464 | Benzo(a)pyrene results in increased expression of RILPL2 mRNA | CTD | PMID:21839799 | Rilpl2 | Rat | bis(2-ethylhexyl) phthalate | increases expression | ISO | Rilpl2 (Mus musculus) | 6480464 | Diethylhexyl Phthalate results in increased expression of RILPL2 mRNA | CTD | PMID:34319233 | Rilpl2 | Rat | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of RILPL2 mRNA | CTD | PMID:25181051 | Rilpl2 | Rat | cadmium atom | multiple interactions | ISO | Rilpl2 (Mus musculus) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of RILPL2 more ... | CTD | PMID:37325564 | Rilpl2 | Rat | cadmium dichloride | decreases expression | EXP | | 6480464 | Cadmium Chloride results in decreased expression of RILPL2 mRNA | CTD | PMID:21297351 | Rilpl2 | Rat | cadmium dichloride | multiple interactions | ISO | Rilpl2 (Mus musculus) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of RILPL2 more ... | CTD | PMID:37325564 | Rilpl2 | Rat | cadmium dichloride | decreases expression | ISO | RILPL2 (Homo sapiens) | 6480464 | Cadmium Chloride results in decreased expression of RILPL2 mRNA | CTD | PMID:38568856 | Rilpl2 | Rat | carbon nanotube | increases expression | ISO | Rilpl2 (Mus musculus) | 6480464 | Nanotubes, Carbon analog results in increased expression of RILPL2 mRNA; Nanotubes, Carbon results in increased more ... | CTD | PMID:25554681 | Rilpl2 | Rat | chlorpyrifos | increases expression | ISO | Rilpl2 (Mus musculus) | 6480464 | Chlorpyrifos results in increased expression of RILPL2 mRNA | CTD | PMID:37019170 | Rilpl2 | Rat | cisplatin | increases expression | ISO | RILPL2 (Homo sapiens) | 6480464 | Cisplatin results in increased expression of RILPL2 mRNA | CTD | PMID:27392435 | Rilpl2 | Rat | cisplatin | multiple interactions | ISO | RILPL2 (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in increased expression of RILPL2 mRNA | CTD | PMID:27392435 | Rilpl2 | Rat | clofibrate | decreases expression | ISO | Rilpl2 (Mus musculus) | 6480464 | Clofibrate results in decreased expression of RILPL2 mRNA | CTD | PMID:23811191 | Rilpl2 | Rat | copper atom | multiple interactions | ISO | RILPL2 (Homo sapiens) | 6480464 | [NSC 689534 binds to Copper] which results in decreased expression of RILPL2 mRNA | CTD | PMID:20971185 | Rilpl2 | Rat | copper(0) | multiple interactions | ISO | RILPL2 (Homo sapiens) | 6480464 | [NSC 689534 binds to Copper] which results in decreased expression of RILPL2 mRNA | CTD | PMID:20971185 | Rilpl2 | Rat | copper(II) sulfate | increases expression | ISO | RILPL2 (Homo sapiens) | 6480464 | Copper Sulfate results in increased expression of RILPL2 mRNA | CTD | PMID:19549813 | Rilpl2 | Rat | cyclosporin A | decreases expression | ISO | RILPL2 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of RILPL2 mRNA | CTD | PMID:20106945|PMID:25562108|PMID:27989131 | Rilpl2 | Rat | Dibutyl phosphate | affects expression | ISO | RILPL2 (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of RILPL2 mRNA | CTD | PMID:37042841 | Rilpl2 | Rat | dibutyl phthalate | decreases expression | ISO | Rilpl2 (Mus musculus) | 6480464 | Dibutyl Phthalate results in decreased expression of RILPL2 mRNA | CTD | PMID:21266533 | Rilpl2 | Rat | dibutyl phthalate | decreases expression | EXP | | 6480464 | Dibutyl Phthalate results in decreased expression of RILPL2 mRNA | CTD | PMID:21266533 | Rilpl2 | Rat | doxorubicin | increases expression | ISO | RILPL2 (Homo sapiens) | 6480464 | Doxorubicin results in increased expression of RILPL2 mRNA | CTD | PMID:29803840 | Rilpl2 | Rat | entinostat | increases expression | ISO | RILPL2 (Homo sapiens) | 6480464 | entinostat results in increased expression of RILPL2 mRNA | CTD | PMID:27188386 | Rilpl2 | Rat | ethanol | increases expression | ISO | Rilpl2 (Mus musculus) | 6480464 | Ethanol results in increased expression of RILPL2 mRNA | CTD | PMID:34492310 | Rilpl2 | Rat | flutamide | decreases expression | EXP | | 6480464 | Flutamide results in decreased expression of RILPL2 mRNA | CTD | PMID:24136188 | Rilpl2 | Rat | folic acid | decreases expression | ISO | Rilpl2 (Mus musculus) | 6480464 | Folic Acid results in decreased expression of RILPL2 mRNA | CTD | PMID:25629700 | Rilpl2 | Rat | folic acid | multiple interactions | ISO | Rilpl2 (Mus musculus) | 6480464 | Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of RILPL2 mRNA] | CTD | PMID:22206623 | Rilpl2 | Rat | leflunomide | decreases expression | ISO | RILPL2 (Homo sapiens) | 6480464 | leflunomide results in decreased expression of RILPL2 mRNA | CTD | PMID:28988120 | Rilpl2 | Rat | Nutlin-3 | multiple interactions | ISO | RILPL2 (Homo sapiens) | 6480464 | [Dactinomycin co-treated with nutlin 3] results in increased expression of RILPL2 mRNA | CTD | PMID:38460933 | Rilpl2 | Rat | paracetamol | affects response to substance | ISO | RILPL2 (Homo sapiens) | 6480464 | RILPL2 gene polymorphism affects the susceptibility to Acetaminophen | CTD | PMID:26104854 | Rilpl2 | Rat | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of RILPL2 mRNA | CTD | PMID:33387578 | Rilpl2 | Rat | paracetamol | decreases expression | ISO | RILPL2 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of RILPL2 mRNA | CTD | PMID:29067470 | Rilpl2 | Rat | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Rilpl2 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Pectins] results in increased expression of RILPL2 mRNA | CTD | PMID:36331819 | Rilpl2 | Rat | perfluorooctanoic acid | multiple interactions | ISO | RILPL2 (Homo sapiens) | 6480464 | [Plasticizers co-treated with Cosmetics co-treated with Flame Retardants co-treated with perfluorooctanoic acid co-treated with Phytoestrogens] more ... | CTD | PMID:33325755 | Rilpl2 | Rat | phytoestrogen | multiple interactions | ISO | RILPL2 (Homo sapiens) | 6480464 | [Plasticizers co-treated with Cosmetics co-treated with Flame Retardants co-treated with perfluorooctanoic acid co-treated with Phytoestrogens] more ... | CTD | PMID:33325755 | Rilpl2 | Rat | progesterone | multiple interactions | ISO | RILPL2 (Homo sapiens) | 6480464 | [Estradiol co-treated with Progesterone] results in decreased expression of RILPL2 mRNA | CTD | PMID:20660070 | Rilpl2 | Rat | quercetin | decreases expression | ISO | RILPL2 (Homo sapiens) | 6480464 | Quercetin results in decreased expression of RILPL2 mRNA | CTD | PMID:21632981 | Rilpl2 | Rat | silicon dioxide | increases expression | ISO | Rilpl2 (Mus musculus) | 6480464 | Silicon Dioxide results in increased expression of RILPL2 mRNA | CTD | PMID:29203145|PMID:29341224 | Rilpl2 | Rat | sodium arsenite | decreases expression | ISO | RILPL2 (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of RILPL2 mRNA | CTD | PMID:38568856 | Rilpl2 | Rat | sodium fluoride | decreases expression | ISO | Rilpl2 (Mus musculus) | 6480464 | Sodium Fluoride results in decreased expression of RILPL2 mRNA | CTD | PMID:27862939 | Rilpl2 | Rat | succimer | multiple interactions | ISO | Rilpl2 (Mus musculus) | 6480464 | [Succimer binds to Magnetite Nanoparticles] which results in increased expression of RILPL2 mRNA | CTD | PMID:21641980 | Rilpl2 | Rat | titanium dioxide | increases methylation | ISO | Rilpl2 (Mus musculus) | 6480464 | titanium dioxide results in increased methylation of RILPL2 gene | CTD | PMID:35295148 | Rilpl2 | Rat | trimellitic anhydride | increases expression | ISO | Rilpl2 (Mus musculus) | 6480464 | trimellitic anhydride results in increased expression of RILPL2 mRNA | CTD | PMID:19042947 | Rilpl2 | Rat | triphenyl phosphate | affects expression | ISO | RILPL2 (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of RILPL2 mRNA | CTD | PMID:37042841 | Rilpl2 | Rat | tris(2-butoxyethyl) phosphate | affects expression | ISO | RILPL2 (Homo sapiens) | 6480464 | tris(2-butoxyethyl) phosphate affects the expression of RILPL2 mRNA | CTD | PMID:29024780 | Rilpl2 | Rat | valproic acid | affects expression | ISO | Rilpl2 (Mus musculus) | 6480464 | Valproic Acid affects the expression of RILPL2 mRNA | CTD | PMID:17292431 | Rilpl2 | Rat | valproic acid | increases expression | ISO | Rilpl2 (Mus musculus) | 6480464 | Valproic Acid results in increased expression of RILPL2 mRNA | CTD | PMID:21427059 | Rilpl2 | Rat | valproic acid | affects expression | ISO | RILPL2 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of RILPL2 mRNA | CTD | PMID:25979313 | Rilpl2 | Rat | valproic acid | increases expression | ISO | RILPL2 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of RILPL2 mRNA | CTD | PMID:23179753|PMID:27188386|PMID:28001369 | |