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Gene: Rabgef1 (RAB guanine nucleotide exchange factor 1) Rattus norvegicus
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Symbol: Rabgef1
Name: RAB guanine nucleotide exchange factor 1
Description: Predicted to have Rab guanyl-nucleotide exchange factor activity and ubiquitin protein ligase activity. Predicted to be involved in several processes, including negative regulation of transport; protein targeting to membrane; and regulation of signal transduction. Predicted to localize to the cytosol; early endosome; and nucleolus. Orthologous to human RABGEF1 (RAB guanine nucleotide exchange factor 1); INTERACTS WITH bisphenol A; caffeine; flutamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC360797; RAB guanine nucleotide exchange factor (GEF) 1; rab5 GDP/GTP exchange factor
Orthologs:
Homo sapiens (human) : RABGEF1 (RAB guanine nucleotide exchange factor 1)  HGNC  Alliance
Mus musculus (house mouse) : Rabgef1 (RAB guanine nucleotide exchange factor (GEF) 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rabgef1 (RAB guanine nucleotide exchange factor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : RABGEF1 (RAB guanine nucleotide exchange factor 1)
Canis lupus familiaris (dog) : RABGEF1 (RAB guanine nucleotide exchange factor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rabgef1 (RAB guanine nucleotide exchange factor 1)
Sus scrofa (pig) : RABGEF1 (RAB guanine nucleotide exchange factor 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01229,960,132 - 30,004,727 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01231,897,731 - 31,942,335 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41227,497,545 - 27,525,385 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11227,360,759 - 27,388,619 (-)NCBI
Celera1228,174,408 - 28,202,245 (-)NCBICelera
Cytogenetic Map12q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Rabgef1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1307295
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.