Gene: Smurf1 (SMAD specific E3 ubiquitin protein ligase 1) Rattus norvegicus
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Symbol: Smurf1
Name: SMAD specific E3 ubiquitin protein ligase 1
Description: ENCODES a protein that exhibits I-SMAD binding (ortholog); R-SMAD binding (ortholog); ubiquitin protein ligase activity (ortholog); INVOLVED IN BMP signaling pathway (ortholog); cell differentiation (ortholog); engulfment of target by autophagosome (ortholog); PARTICIPATES IN Bone morphogenetic proteins signaling pathway; transforming growth factor-beta Smad dependent signaling pathway; ASSOCIATED WITH Spinal Cord Injuries; pancreatic cancer (ortholog); pleomorphic xanthoastrocytoma (ortholog); FOUND IN axon; neuronal cell body; cytoplasm (ortholog); INTERACTS WITH 1,3-dinitrobenzene; 17beta-estradiol; bisphenol A
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: E3 ubiquitin-protein ligase SMURF1; LOC690516; RGD1309707; similar to Smad ubiquitination regulatory factor 1 isoform 2
Orthologs:
Homo sapiens (human) : SMURF1 (SMAD specific E3 ubiquitin protein ligase 1)  HGNC  Alliance
Mus musculus (house mouse) : Smurf1 (SMAD specific E3 ubiquitin protein ligase 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Smurf1 (SMAD specific E3 ubiquitin protein ligase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : SMURF1 (SMAD specific E3 ubiquitin protein ligase 1)
Canis lupus familiaris (dog) : SMURF1 (SMAD specific E3 ubiquitin protein ligase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Smurf1 (SMAD specific E3 ubiquitin protein ligase 1)
Sus scrofa (pig) : SMURF1 (SMAD specific E3 ubiquitin protein ligase 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01211,433,815 - 11,526,465 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01213,499,018 - 13,591,105 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4129,950,304 - 10,042,391 (+)NCBIRGSC3.4rn4RGSC3.4
Celera1211,439,779 - 11,530,606 (+)NCBICelera
Cytogenetic Map12p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Smurf1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1594738
Created: 2006-11-20
Species: Rattus norvegicus
Last Modified: 2019-01-30
Status: ACTIVE