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Gene: Lat2 (linker for activation of T cells family, member 2) Rattus norvegicus
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Symbol: Lat2
Name: linker for activation of T cells family, member 2
RGD ID: 631397
Description: Predicted to have SH2 domain binding activity. Predicted to be involved in B cell activation; B cell receptor signaling pathway; and calcium-mediated signaling. Predicted to localize to membrane raft and plasma membrane. Human ortholog(s) of this gene implicated in Williams-Beuren syndrome. Orthologous to human LAT2 (linker for activation of T cells family member 2); INTERACTS WITH acetamide; ammonium chloride; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LAT-2 like; linker for activation of B-cells; linker for activation of T-cells family member 2; non-T cell activation linker; non-T-cell activation linker; Ntal; Wbscr5; Williams-Beuren syndrome chromosome region 5 homolog; Williams-Beuren syndrome chromosome region 5 homolog (human); Williams-Beuren syndrome chromosome region 5-like protein
Orthologs:
Homo sapiens (human) : LAT2 (linker for activation of T cells family member 2)  HGNC  Alliance
Mus musculus (house mouse) : Lat2 (linker for activation of T cells family, member 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lat2 (linker for activation of T cells family member 2)
Pan paniscus (bonobo/pygmy chimpanzee) : LAT2 (linker for activation of T cells family member 2)
Canis lupus familiaris (dog) : LAT2 (linker for activation of T cells family member 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lat2 (linker for activation of T cells family member 2)
Sus scrofa (pig) : LAT2 (linker for activation of T cells family member 2)
Chlorocebus sabaeus (African green monkey) : LAT2 (linker for activation of T cells family member 2)
Heterocephalus glaber (naked mole-rat) : Lat2 (linker for activation of T cells family member 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01225,114,099 - 25,128,381 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1225,119,355 - 25,125,749 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01227,114,507 - 27,128,775 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41223,174,554 - 23,180,908 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11223,035,110 - 23,041,465 (+)NCBI
Celera1223,873,387 - 23,879,734 (+)NCBICelera
Cytogenetic Map12q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Lat2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 631397
Created: 2003-08-13
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.