Lat2 (linker for activation of T cells family, member 2)

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Gene: Lat2 (linker for activation of T cells family, member 2) Rattus norvegicus

Analyze

Symbol:

Lat2

Name:

linker for activation of T cells family, member 2

RGD ID:

631397

Description:

Predicted to have SH2 domain binding activity. Predicted to be involved in B cell activation; B cell receptor signaling pathway; and calcium-mediated signaling. Predicted to localize to membrane raft and plasma membrane. Human ortholog(s) of this gene implicated in Williams-Beuren syndrome. Orthologous to human LAT2 (linker for activation of T cells family member 2); INTERACTS WITH acetamide; ammonium chloride; bisphenol A.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Also known as:

LAT-2 like; linker for activation of B-cells; linker for activation of T-cells family member 2; non-T cell activation linker; non-T-cell activation linker; Ntal; Wbscr5; Williams-Beuren syndrome chromosome region 5 homolog; Williams-Beuren syndrome chromosome region 5 homolog (human); Williams-Beuren syndrome chromosome region 5-like protein

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

Latest Assembly:

Rnor_6.0 - RGSC Genome Assembly v6.0

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	12	22,104,163 - 22,118,294 (+)	NCBI
Rnor_6.0 Ensembl	12	25,119,355 - 25,125,749 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0	12	25,114,099 - 25,128,381 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	12	27,114,507 - 27,128,775 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	12	23,174,554 - 23,180,908 (+)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	12	23,035,110 - 23,041,465 (+)	NCBI
Celera	12	23,873,387 - 23,879,734 (+)	NCBI		Celera
Cytogenetic Map	12	q12	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autism spectrum disorder (ISO)

autistic disorder (ISO)

intestinal volvulus (ISO)

Neurodevelopmental Disorders (ISO)

pleomorphic xanthoastrocytoma (ISO)

schizophrenia (ISO)

Volvulus Of Midgut (ISO)

Williams-Beuren syndrome (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2-bromohexadecanoic acid (ISO)

8-Br-cAMP (ISO)

acetamide (EXP)

acrolein (ISO)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

alpha-pinene (ISO)

ammonium chloride (EXP)

antirheumatic drug (ISO)

arsenous acid (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

buta-1,3-diene (ISO)

butanal (ISO)

cadmium dichloride (EXP)

calcitriol (ISO)

carbon nanotube (ISO)

chlorpyrifos (ISO)

choline (ISO)

copper(II) sulfate (ISO)

dextran sulfate (ISO)

diarsenic trioxide (ISO)

ethyl methanesulfonate (ISO)

folic acid (ISO)

formaldehyde (ISO)

graphite (EXP)

ixazomib (ISO)

L-methionine (ISO)

lead diacetate (ISO)

lead(0) (ISO)

lead(2+) (ISO)

methyl beta-cyclodextrin (ISO)

methyl methanesulfonate (ISO)

N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal (ISO)

nickel atom (ISO)

O-methyleugenol (ISO)

ozone (ISO)

paracetamol (ISO)

paraoxon (ISO)

pentanal (ISO)

perifosine (ISO)

pirinixic acid (ISO)

propanal (ISO)

silicon dioxide (ISO)

sodium dichromate (ISO)

testosterone (ISO)

tetrachloromethane (EXP)

titanium dioxide (ISO)

valproic acid (ISO)

wortmannin (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

adaptive immune response (IEA)

B cell activation (IBA,IEA,ISO)

B cell receptor signaling pathway (IBA,ISO)

calcium-mediated signaling (IBA,ISO)

immune response-regulating signaling pathway (IEA)

intracellular signal transduction (ISO)

mast cell degranulation (IEA)

Cellular Component

integral component of membrane (IEA)

membrane raft (ISO)

plasma membrane (IBA,ISO)

Molecular Function

protein binding (ISO)

SH2 domain binding (ISO)

References

References - curated


1.	Brdicka T, etal., J Exp Med 2002 Dec 16;196(12):1617-26.
2.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	Martindale DW, etal., Mamm Genome 2000 Oct;11(10):890-8.
4.	RGD automated data pipeline
5.	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12514734	PMID:14722116	PMID:15477348	PMID:17013982	PMID:17911602	PMID:20442417	PMID:20458337	PMID:21403644	PMID:23443658	PMID:26448619	PMID:29099056

Genomics

Comparative Map Data

Lat2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	12	22,104,163 - 22,118,294 (+)	NCBI
Rnor_6.0 Ensembl	12	25,119,355 - 25,125,749 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0	12	25,114,099 - 25,128,381 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	12	27,114,507 - 27,128,775 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	12	23,174,554 - 23,180,908 (+)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	12	23,035,110 - 23,041,465 (+)	NCBI
Celera	12	23,873,387 - 23,879,734 (+)	NCBI		Celera
Cytogenetic Map	12	q12	NCBI

LAT2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38.p13 Ensembl	7	74,199,652 - 74,229,834 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh38	7	74,210,006 - 74,229,834 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh37	7	73,624,336 - 73,644,164 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	7	73,262,023 - 73,282,100 (+)	NCBI	NCBI36		hg18	NCBI36
Build 34	7	73,068,925 - 73,088,808	NCBI
Celera	7	69,103,651 - 69,123,730 (+)	NCBI
Cytogenetic Map	7	q11.23	NCBI
HuRef	7	69,505,694 - 69,525,599 (+)	NCBI		HuRef
CHM1_1	7	73,769,175 - 73,789,226 (+)	NCBI		CHM1_1
CRA_TCAGchr7v2	7	72,957,159 - 72,977,236 (+)	NCBI

Lat2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	5	134,628,957 - 134,648,637 (-)	NCBI	GRCm39		mm39
GRCm39 Ensembl	5	134,628,876 - 134,643,879 (-)	Ensembl
GRCm38	5	134,600,103 - 134,619,783 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	5	134,600,022 - 134,615,025 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	5	135,076,135 - 135,090,893 (-)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	5	134,884,892 - 134,899,650 (-)	NCBI			mm8
Celera	5	131,608,314 - 131,623,075 (-)	NCBI		Celera
Cytogenetic Map	5	G2	NCBI

Lat2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955456	13,674,190 - 13,688,611 (-)	NCBI	ChiLan1.0	ChiLan1.0

LAT2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	7	81,350,666 - 81,377,115 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	7	81,350,666 - 81,377,115 (+)	Ensembl	panpan1.1		panPan2

LAT2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1 Ensembl	6	6,161,542 - 6,173,294 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
CanFam3.1	6	6,160,939 - 6,175,271 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1

Lat2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
SpeTri2.0	NW_004936543	3,250,956 - 3,262,668 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

LAT2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	3	11,352,579 - 11,372,096 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	3	11,353,213 - 11,372,100 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	3	11,036,844 - 11,055,323 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

LAT2
(Chlorocebus sabaeus - African green monkey)

Vervet Assembly	Chr	Position (strand)	Source	Genome Browsers
Vervet Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	28	8,848,971 - 8,865,558 (-)	NCBI
ChlSab1.1 Ensembl	28	8,848,638 - 8,865,574 (-)	Ensembl

Lat2
(Heterocephalus glaber - naked mole-rat)

Molerat Assembly	Chr	Position (strand)	Source	Genome Browsers
Molerat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624740	13,745,949 - 13,764,869 (-)	NCBI

QTLs in Region (Rnor_6.0)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1581516	Cm56	Cardiac mass QTL 56	4.2	0.05	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	12	1	30749723	Rat
1598855	Bp294	Blood pressure QTL 294	3.5		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	12	1	36919844	Rat
7387292	Kidm42	Kidney mass QTL 42	3.03	0.0004	kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	12	1	38334225	Rat
9590086	Insglur6	Insulin/glucose ratio QTL 6	18.97	0.001	blood insulin amount (VT:0001560)	calculated plasma insulin level (CMO:0002170)	12	150810	45150810	Rat
9590147	Scort7	Serum corticosterone level QTL 7	13.61	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	12	150810	45150810	Rat
7411545	Bw128	Body weight QTL 128	5.2	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	12	150810	45150810	Rat
7411586	Foco5	Food consumption QTL 5	5.4	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	150810	45150810	Rat
7411660	Foco28	Food consumption QTL 28	10.9	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	150810	45150810	Rat
7411595	Foco9	Food consumption QTL 9	4	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	150810	45150810	Rat
8694179	Bw150	Body weight QTL 150	2.9	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	12	150810	45150810	Rat
2303575	Insul14	Insulin level QTL 14	4		blood insulin amount (VT:0001560)	blood insulin level (CMO:0000349)	12	492578	45492578	Rat
737979	Pia22	Pristane induced arthritis QTL 22	53.1		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	12	2475687	47475687	Rat
634351	Apr5	Acute phase response QTL 5	6.7		blood interleukin-6 amount (VT:0008595)	plasma interleukin-6 level (CMO:0001927)	12	2513442	47513442	Rat
2302042	Pia38	Pristane induced arthritis QTL 38	3.5	0.001	blood immunoglobulin amount (VT:0002460)	serum immunoglobulin G1 level (CMO:0002115)	12	2513442	47513442	Rat
634350	Apr4	Acute phase response QTL 4	6		orosomucoid 1 amount (VT:0010541)	plasma orosomucoid 1 level (CMO:0001467)	12	4210051	49210051	Rat
1302792	Scl21	Serum cholesterol level QTL 21	3.8	0.0011	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	12	8954593	27911196	Rat
7411547	Bw129	Body weight QTL 129		0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	6	9223626	52716770	Rat
7411588	Foco6	Food consumption QTL 6		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	9223626	52716770	Rat
7411597	Foco10	Food consumption QTL 10		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	9223626	52716770	Rat
7411641	Foco19	Food consumption QTL 19	27.7	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	9223626	52716770	Rat
8552918	Pigfal7	Plasma insulin-like growth factor 1 level QTL 7			blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	12	9223626	52716770	Rat
8552964	Pigfal17	Plasma insulin-like growth factor 1 level QTL 17	3.5		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	12	9223626	52716770	Rat
8552912	Pigfal6	Plasma insulin-like growth factor 1 level QTL 6	5		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	12	9223630	52716770	Rat
10059594	Kidm46	Kidney mass QTL 46	3.79	0.025	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	12	9789834	52716770	Rat
2293086	Iddm30	Insulin dependent diabetes mellitus QTL 30	3.82		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	12	10175889	31975590	Rat
61331	Eau2	Experimental allergic uveoretinitis QTL 2		0.0005	uvea integrity trait (VT:0010551)	experimental autoimmune uveitis score (CMO:0001504)	12	10256890	31723732	Rat
1300157	Rf21	Renal function QTL 21	4.4		renal blood flow trait (VT:2000006)	absolute change in renal blood flow rate (CMO:0001168)	12	11764995	37522089	Rat
1331786	Kidm11	Kidney mass QTL 11	3.571		kidney mass (VT:0002707)	right kidney wet weight (CMO:0000082)	12	13127211	27285590	Rat
1331755	Bp219	Blood pressure QTL 219	3.041		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	12	13127211	31723688	Rat
1331761	Bp218	Blood pressure QTL 218	2.973		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	12	13127211	50320041	Rat
61404	Bw120	Body weight QTL 120	5.1		body mass (VT:0001259)	body mass index (BMI) (CMO:0000105)	12	14419775	52716770	Rat
1549829	Scl48	Serum cholesterol level QTL 48	5		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	12	15021986	52716770	Rat
61416	Pia4	Pristane induced arthritis QTL 4	8.4		joint integrity trait (VT:0010548)	arthritic paw count (CMO:0001460)	12	15714609	35964508	Rat
61421	Cia12	Collagen induced arthritis QTL 12	4.6		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	12	15714609	41291738	Rat
2300186	Bmd59	Bone mineral density QTL 59	7.1	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	12	15908900	52716770	Rat
2293699	Bss49	Bone structure and strength QTL 49	5.61	0.0001	lumbar vertebra size trait (VT:0010518)	lumbar vertebra trabecular cross-sectional area (CMO:0001692)	12	15908900	52716770	Rat
631543	Bp83	Blood pressure QTL 83	5.8		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	12	17185580	44098244	Rat
2293684	Bmd26	Bone mineral density QTL 26	4.4	0.0002	femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	12	17960865	38409001	Rat
1641928	Alcrsp5	Alcohol response QTL 5			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	12	18342477	52716770	Rat
2303569	Gluco44	Glucose level QTL 44	2		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	12	18342477	52716770	Rat
2302060	Pia37	Pristane induced arthritis QTL 37	6.1	0.001	blood immunoglobulin amount (VT:0002460)	serum immunoglobulin G1 level (CMO:0002115)	12	18729043	52716770	Rat
1549902	Bp269	Blood pressure QTL 269			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	12	18752593	52716770	Rat
1549912	Bp268	Blood pressure QTL 268			arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	10	18752593	52716770	Rat
2306789	Ean6	Experimental allergic neuritis QTL 6	4.9		nervous system integrity trait (VT:0010566)	experimental autoimmune neuritis severity score (CMO:0001528)	12	22650702	27190240	Rat
737822	Alc10	Alcohol consumption QTL 10	2.2		consumption behavior trait (VT:0002069)	ethanol drink intake rate (CMO:0001407)	12	22650702	45946937	Rat
5684888	Pia42	Pristane induced arthritis QTL 42			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	12	22650702	48598906	Rat
61324	Eae5	Experimental allergic encephalomyelitis QTL 5	14		nervous system integrity trait (VT:0010566)	percentage of study population developing relapsing-remitting experimental autoimmune encephalomyelitis during a period of time (CMO:0001402)	12	22650702	52716770	Rat
1298081	Cia25	Collagen induced arthritis QTL 25	4.7		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	12	22650721	41291738	Rat
70213	Niddm27	Non-insulin dependent diabetes mellitus QTL 27	3.72		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	12	22876297	43799153	Rat
631521	Pia12	Pristane induced arthritis QTL 12	8.9		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	12	23241246	26710128	Rat
631560	Apr1	Acute phase response QTL 1	6.1		orosomucoid 1 amount (VT:0010541)	plasma orosomucoid 1 level (CMO:0001467)	12	24906590	52716770	Rat

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	64
Count of miRNA genes:	60
Interacting mature miRNAs:	63
Transcripts:	ENSRNOT00000034629
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	2	1	8		19						3	9
Low	1	24	49	41		41	8	10	62	31	33	2	8
Below cutoff		14						1	10	4	5

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_173840	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006249160	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017598358	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039089531	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039089532	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039089533	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039089534	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005491642	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005491643	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AB219140	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AC091000	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AC135741	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY170849	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473973	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	DQ294696	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	DQ294697	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	DQ294698	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	DQ294699	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ226685	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ231408	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ234957	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ235223	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000227	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000034629 ⟹ ENSRNOP00000031304

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	12	25,119,355 - 25,125,749 (+)	Ensembl

RefSeq Acc Id:

NM_173840 ⟹ NP_776212

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	12	22,109,452 - 22,115,807 (+)	NCBI
Rnor_6.0	12	25,119,379 - 25,125,733 (+)	NCBI
Rnor_5.0	12	27,114,507 - 27,128,775 (+)	NCBI
RGSC_v3.4	12	23,174,554 - 23,180,908 (+)	RGD
Celera	12	23,873,387 - 23,879,734 (+)	RGD

Sequence:

show sequence

ATGAATGCCGAGTTGGAGCTGCTGTGGCCACTGTCAGGACTGTTGCTGCTGCTGCTCTTGGGGA
CCACAGCTTGGCTGTGTGTCCAGTGCTCCCGCCCAGGGGTGAAGAGAAATGAGAAAATCTACGA
GCAGAGGAACCAGCAAGAAAATGAACAGAGCGTAGCCTCATCTCAGACGTACTCCCTGGCCAGG
CCGGTGCGGACAGGACTCCAGATGGACGCAGCCTCAAACAAGTCATTTGAGAGGAAGAACAAGC
TGCTTTTCTCCCACCTGGAGGGTCCTGAGTCCCCTAGGTACCAGAACTTCTACAAAGGAAGCAG
ACGGGAGTCTGATGCTGCCTATGTAGATCCCATCCCCACAGACTACTACAACTGGGGATGTTTC
CAGAAGCCCCCAGAAGACAATGATTCCAACTCCTACGAGAATGTGCTCATCTGCAAGCCCAGCA
CCCCCGAGTCAGGTACTGAGGAATCCGAGGATTACCAGAACTCGGTATCCATCCTTCAGTGGCG
AGAATCCAAGAGGACTATGGGTGCACGCACGTCCCCATCAGGAAGCCCAGACGAGGAGCCAGAT
TACGTGAATGGGGATGTGGCCACGACGGAGAAAATCTAG

hide sequence

RefSeq Acc Id:

XM_006249160 ⟹ XP_006249222

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	12	22,104,163 - 22,118,289 (+)	NCBI
Rnor_6.0	12	25,114,099 - 25,128,381 (+)	NCBI
Rnor_5.0	12	27,114,507 - 27,128,775 (+)	NCBI

Sequence:

show sequence

CGAGGCGGATGTAGAGGGATGATTCAGTAGTGACAGGAAGCCAACTGCCTTGCCCGCTGCTCGC
CAGAGTCAGTGGTGCTGTTGGCATCAGCCTGGGCAGGTGTGCGGGCACAGGATGAAGTGGCCAT
GGTGAGGAGCCCTCATTCTCAGCTTTGCAGCTCCCTCCCCAAGCCAACATGAGTGCCGAGTTGG
AGCTGCTGTGGCCACTGTCAGGACTGTTGCTGCTGCTGCTCTTGGGGACCACAGCTTGGCTGTG
TGTCCAGTGCTCCCGCCCAGGGGTGAAGAGAAATGAGAAAATCTACGAGCAAAGGAACCAGCAA
GAAAATGAACAGAGCGTAGCCTCGTCTCAGACGTACTCCCTGGCCAGGCCGGTGCGGACAGGAC
TCCAGATGGACGCAGCCTCAAACAAGTCATTTGAGAGGAAGAACAAGCTGCTTTTCTCCCACCT
GGAGGGTCCTGAGTCCCCTAGGTACCAGAACTTCTACAAAGGAAGCAGACGGGAGTCTGATGCT
GCCTATGTAGATCCCATCCCCACGGACTACTACAACTGGGGATGTTTCCAGAAGCCCCCAGAAG
ACAATGATTCCAACTCCTACGAGAATGTGCTCATCTGCAAGCCCAGCACCCCCGAGTCAGGTAC
TGAGGAATCCGAGGATTACCAGAACTCGGTATCCATCCTTCAGTGGCGAGAATCCAAGAGGACT
ATGGGTGCACGCACGTCCCCATCAGGAAGCCCAGACGAGGAGCCAGATTACGTGAATGGGGATG
TGGCCACGACGGAGAAAATCTAGGAGAGAATCCAAAGGAAGGGCCTGAGGATCAGGAGCCGACT
GTTTACTGCCTGCTGTATAAAGCCCTGACTGTGGCTGCTCCTGGGAGGGGCACCAGAACTGCCT
GACACTGCCTGGGAGACATTGGAATCACCAGGGCTGCAAGTGATGCTCCGGACTTCTCAGGGAC
AAAGCAAGTGTCCAGGGGATATTGACTGTGCTGACTGGAAGCCCAGGACCTGAGGCAGGATGCA
TCCCCAGTCCCACATCTAAAATGCAGCACAACATTGGCACTTGTGGGTTTTGTTTTGGCTGTAG
GTCTAAATTGTTCAGGCTGATGTCAAACTTGCAATCCTCCAGCCTCAGCCCTTGTGCTGGGATC
ACGTTATACCACCACACCTGACTTCGTAGGGTGGTTTTGTTTTTTTTTTTGTTTTTTTTTCCTT
TCCTTGTTTGAACCTCAAACTACTTATGAATGTTGATTTCTGGAACTGTTACCATGACTTTTCC
GGTAGTTAACTTAAGTTGCTGGAGCCGTATTTAATGTTGTTAATGTCAGGGGACTCCCCGTTTC
AGAGCATTAAATGTAGTAGCCTTAGCAGAAGAATGGGGTGTGGGGTAACCTGAGATTGCCTTGG
TTTCTTACGAGGCTCCAGTTTGTTCTGATTTTCCATTCCTGCGGGGGGGAACCTTGTGGGCCAG
TGATAAAGAAATAAAACCACCCCCTCATCAAACCTCAGGAAACCCTGTGTGTAAGAGCAGGCAC
AGCGCACATGCCTTTTAGACACCTTTTCCTGTGTGTTCCTAGGGTCTACCATCTGCTGTTCCTC
TCCATTATTTTAACAGTCACACTGTGTAGCCCCTGGCTGGCCTGGAACTTGCTGTATAAAGCAG
GCTGGCCCTAA

hide sequence

RefSeq Acc Id:

XM_017598357 ⟹ XP_017453846

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	12	25,119,846 - 25,128,381 (+)	NCBI

Sequence:

show sequence

AAATGTTCCTGCCCTCTGGCCTCAGCTTCCTGAGCCCTGGGATCACAGACCTGTGTCACCACAC
CCAGCTGACAAGAACCCTCTCAGTGACAGGCAGCTGGAAGGGACAGCCTGGTGGAGTTACAAAG
GGGAGGAGGGGTTCCAGACTTCAGCCCTCCCCCACTGCACCCCCTGAGTTCAGGGACACTAGCT
ACGCCATTTCTGTTCTTGCAGGGGTGAAGAGAAATGAGAAAATCTACGAGCAAAGGAACCAGCA
AGAAAATGAACAGAGCGTAGCCTCGTCTCAGACGTACTCCCTGGCCAGGCCGGTGCGGACAGGA
CTCCAGATGGACGCAGCCTCAAACAAGTCATTTGAGAGGAAGAACAAGCTGCTTTTCTCCCACC
TGGAGGGTCCTGAGTCCCCTAGGTACCAGAACTTCTACAAAGGAAGCAGACGGGAGTCTGATGC
TGCCTATGTAGATCCCATCCCCACGGACTACTACAACTGGGGATGTTTCCAGAAGCCCCCAGAA
GACAATGATTCCAACTCCTACGAGAATGTGCTCATCTGCAAGCCCAGCACCCCCGAGTCAGGTA
CTGAGGAATCCGAGGATTACCAGAACTCGGTATCCATCCTTCAGTGGCGAGAATCCAAGAGGAC
TATGGGTGCACGCACGTCCCCATCAGGAAGCCCAGACGAGGAGCCAGATTACGTGAATGGGGAT
GTGGCCACGACGGAGAAAATCTAGGAGAGAATCCAAAGGAAGGGCCTGAGGATCAGGAGCCGAC
TGTTTACTGCCTGCTGTATAAAGCCCTGACTGTGGCTGCTCCTGGGAGGGGCACCAGAACTGCC
TGACACTGCCTGGGAGACATTGGAATCACCAGGGCTGCAAGTGATGCTCCGGACTTCTCAGGGA
CAAAGCAAGTGTCCAGGGGATATTGACTGTGCTGACTGGAAGCCCAGGACCTGAGGCAGGATGC
ATCCCCAGTCCCACATCTAAAATGCAGCACAACATTGGCACTTGTGGGTTTTGTTTTGGCTGTA
GGTCTAAATTGTTCAGGCTGATGTCAAACTTGCAATCCTCCAGCCTCAGCCCTTGTGCTGGGAT
CACGTTATACCACCACACCTGACTTCGTAGGGTGGTTTTGTTTTTTTTTTTGTTTTTTTTTCCT
TTCCTTGTTTGAACCTCAAACTACTTATGAATGTTGATTTCTGGAACTGTTACCATGACTTTTC
CGGTAGTTAACTTAAGTTGCTGGAGCCGTATTTAATGTTGTTAATGTCAGGGGACTCCCCGTTT
CAGAGCATTAAATGTAGTAGCCTTAGCAGAAGAATGGGGTGTGGGGTAACCTGAGATTGCCTTG
GTTTCTTACGAGGCTCCAGTTTGTTCTGATTTTCCATTCCTGCGGGGGGGAACCTTGTGGGCCA
GTGATAAAGAAATAAAACCACCCCCTCATCAAACCTCAGGAAACCCTGTGTGTAAGAGCAGGCA
CAGCGCACATGCCTTTTAGACACCTTTTCCTGTGTGTTCCTAGGGTCTACCATCTGCTGTTCCT
CTCCATTATTTTAACAGTCACACTGTGTAGCCCCTGGCTGGCCTGGAACTTGCTGTATAAAGCA
GGCTGGCCCTAA

hide sequence

RefSeq Acc Id:

XM_017598358 ⟹ XP_017453847

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	12	22,104,179 - 22,118,294 (+)	NCBI
Rnor_6.0	12	25,119,846 - 25,128,381 (+)	NCBI

Sequence:

show sequence

AAATGTTCCTGCCCTCTGGCCTCAGCTTCCTGAGCCCTGGGATCACAGACCTGTGTCACCACAC
CCAGCTGACAAGAACCCTCTCAGTGACAGGCAGCTGGAAGGGACAGCCTGGTGGAGTTACAAAG
GGGAGGAGGGGTTCCAGACTTCAGCCCTCCCCCACTGCACCCCCTGAGTTCAGGGACACTAGCT
ACGCCATTTCTGTTCTTGCAGGGGTGAAGAGAAATGAGAAAATCTACGAGCAAAGGAACCAGCA
AGAAAATGAACAGAGCGTAGCCTCGTCTCAGACGTACTCCCTGGCCAGGCCGGTGCGGACAGGA
CTCCAGATGGACGCAGCCTCAAACAAGTCATTTGAGAGGAAGAACAAGCTGCTTTTCTCCCACC
TGGAGGGAAGCAGACGGGAGTCTGATGCTGCCTATGTAGATCCCATCCCCACGGACTACTACAA
CTGGGGATGTTTCCAGAAGCCCCCAGAAGACAATGATTCCAACTCCTACGAGAATGTGCTCATC
TGCAAGCCCAGCACCCCCGAGTCAGGTACTGAGGAATCCGAGGATTACCAGAACTCGGTATCCA
TCCTTCAGTGGCGAGAATCCAAGAGGACTATGGGTGCACGCACGTCCCCATCAGGAAGCCCAGA
CGAGGAGCCAGATTACGTGAATGGGGATGTGGCCACGACGGAGAAAATCTAGGAGAGAATCCAA
AGGAAGGGCCTGAGGATCAGGAGCCGACTGTTTACTGCCTGCTGTATAAAGCCCTGACTGTGGC
TGCTCCTGGGAGGGGCACCAGAACTGCCTGACACTGCCTGGGAGACATTGGAATCACCAGGGCT
GCAAGTGATGCTCCGGACTTCTCAGGGACAAAGCAAGTGTCCAGGGGATATTGACTGTGCTGAC
TGGAAGCCCAGGACCTGAGGCAGGATGCATCCCCAGTCCCACATCTAAAATGCAGCACAACATT
GGCACTTGTGGGTTTTGTTTTGGCTGTAGGTCTAAATTGTTCAGGCTGATGTCAAACTTGCAAT
CCTCCAGCCTCAGCCCTTGTGCTGGGATCACGTTATACCACCACACCTGACTTCGTAGGGTGGT
TTTGTTTTTTTTTTTGTTTTTTTTTCCTTTCCTTGTTTGAACCTCAAACTACTTATGAATGTTG
ATTTCTGGAACTGTTACCATGACTTTTCCGGTAGTTAACTTAAGTTGCTGGAGCCGTATTTAAT
GTTGTTAATGTCAGGGGACTCCCCGTTTCAGAGCATTAAATGTAGTAGCCTTAGCAGAAGAATG
GGGTGTGGGGTAACCTGAGATTGCCTTGGTTTCTTACGAGGCTCCAGTTTGTTCTGATTTTCCA
TTCCTGCGGGGGGGAACCTTGTGGGCCAGTGATAAAGAAATAAAACCACCCCCTCATCAAACCT
CAGGAAACCCTGTGTGTAAGAGCAGGCACAGCGCACATGCCTTTTAGACACCTTTTCCTGTGTG
TTCCTAGGGTCTACCATCTGCTGTTCCTCTCCATTATTTTAACAGTCACACTGTGTAGCCCCTG
GCTGGCCTGGAACTTGCTGTATAAAGCAGGCTGGCCCTAA

hide sequence

RefSeq Acc Id:

XM_017598359 ⟹ XP_017453848

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	12	25,114,099 - 25,128,381 (+)	NCBI

Sequence:

show sequence

CGAGGCGGATGTAGAGGGATGATTCAGTAGTGACAGGAAGCCAACTGCCTTGCCCGCTGCTCGC
CAGAGTCAGTGGTGCTGTTGGCATCAGCCTGGGCAGGTGTGCGGGCACAGGATGAAGTGGCCAT
GGTGAGGAGCCCTCATTCTCAGCTTTGCAGCTCCCTCCCCAAGCCAACATGAGTGCCGAGTTGG
AGCTGCTGTGGCCACTGTCAGGACTGTTGCTGCTGCTGCTCTTGGGGACCACAGCTTGGCTGTG
TGTCCAGTGCTCCCGCCCAGGGGTGAAGAGAAATGAGAAAATCTACGAGCAAAGGAACCAGCAA
GAAAATGAACAGAGCGTAGCCTCGTCTCAGACGTACTCCCTGGCCAGGCCGGTGCGGACAGGAC
TCCAGATGGACGCAGCCTCAAACAAGTCATTTGAGAGGAAGAACAAGCTGCTTTTCTCCCACCT
GGAGGGAAGCAGACGGGAGTCTGATGCTGCCTATGTAGATCCCATCCCCACGGACTACTACAAC
TGGGGATGTTTCCAGAAGCCCCCAGAAGACAATGATTCCAACTCCTACGAGAATGTGCTCATCT
GCAAGCCCAGCACCCCCGAGTCAGGTACTGAGGAATCCGAGGATTACCAGAACTCGGTATCCAT
CCTTCAGTGGCGAGAATCCAAGAGGACTATGGGTGCACGCACGTCCCCATCAGGAAGCCCAGAC
GAGGAGCCAGATTACGTGAATGGGGATGTGGCCACGACGGAGAAAATCTAGGAGAGAATCCAAA
GGAAGGGCCTGAGGATCAGGAGCCGACTGTTTACTGCCTGCTGTATAAAGCCCTGACTGTGGCT
GCTCCTGGGAGGGGCACCAGAACTGCCTGACACTGCCTGGGAGACATTGGAATCACCAGGGCTG
CAAGTGATGCTCCGGACTTCTCAGGGACAAAGCAAGTGTCCAGGGGATATTGACTGTGCTGACT
GGAAGCCCAGGACCTGAGGCAGGATGCATCCCCAGTCCCACATCTAAAATGCAGCACAACATTG
GCACTTGTGGGTTTTGTTTTGGCTGTAGGTCTAAATTGTTCAGGCTGATGTCAAACTTGCAATC
CTCCAGCCTCAGCCCTTGTGCTGGGATCACGTTATACCACCACACCTGACTTCGTAGGGTGGTT
TTGTTTTTTTTTTTGTTTTTTTTTCCTTTCCTTGTTTGAACCTCAAACTACTTATGAATGTTGA
TTTCTGGAACTGTTACCATGACTTTTCCGGTAGTTAACTTAAGTTGCTGGAGCCGTATTTAATG
TTGTTAATGTCAGGGGACTCCCCGTTTCAGAGCATTAAATGTAGTAGCCTTAGCAGAAGAATGG
GGTGTGGGGTAACCTGAGATTGCCTTGGTTTCTTACGAGGCTCCAGTTTGTTCTGATTTTCCAT
TCCTGCGGGGGGGAACCTTGTGGGCCAGTGATAAAGAAATAAAACCACCCCCTCATCAAACCTC
AGGAAACCCTGTGTGTAAGAGCAGGCACAGCGCACATGCCTTTTAGACACCTTTTCCTGTGTGT
TCCTAGGGTCTACCATCTGCTGTTCCTCTCCATTATTTTAACAGTCACACTGTGTAGCCCCTGG
CTGGCCTGGAACTTGCTGTATAAAGCAGGCTGGCCCTAA

hide sequence

RefSeq Acc Id:

XM_039089531 ⟹ XP_038945459

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	12	22,104,180 - 22,118,289 (+)	NCBI

RefSeq Acc Id:

XM_039089532 ⟹ XP_038945460

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	12	22,104,173 - 22,114,650 (+)	NCBI

RefSeq Acc Id:

XM_039089533 ⟹ XP_038945461

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	12	22,104,173 - 22,114,650 (+)	NCBI

RefSeq Acc Id:

XM_039089534 ⟹ XP_038945462

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	12	22,104,223 - 22,118,289 (+)	NCBI

RefSeq Acc Id:

XR_005491642

RefSeq Status:

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	12	22,104,174 - 22,115,308 (+)	NCBI

RefSeq Acc Id:

XR_005491643

RefSeq Status:

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	12	22,104,174 - 22,115,308 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_776212	(Get FASTA)	NCBI Sequence Viewer
	XP_006249222	(Get FASTA)	NCBI Sequence Viewer
	XP_017453847	(Get FASTA)	NCBI Sequence Viewer
	XP_038945459	(Get FASTA)	NCBI Sequence Viewer
	XP_038945460	(Get FASTA)	NCBI Sequence Viewer
	XP_038945461	(Get FASTA)	NCBI Sequence Viewer
	XP_038945462	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAO12808	(Get FASTA)	NCBI Sequence Viewer
	ABB88414	(Get FASTA)	NCBI Sequence Viewer
	ABB88415	(Get FASTA)	NCBI Sequence Viewer
	ABB88416	(Get FASTA)	NCBI Sequence Viewer
	ABB88417	(Get FASTA)	NCBI Sequence Viewer
	EDM13420	(Get FASTA)	NCBI Sequence Viewer
	EDM13421	(Get FASTA)	NCBI Sequence Viewer
	EDM13422	(Get FASTA)	NCBI Sequence Viewer
	Q8CGL2	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:	NP_776212 ⟸ NM_173840
- Peptide Label:	precursor
- UniProtKB:	Q8CGL2 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MNAELELLWPLSGLLLLLLLGTTAWLCVQCSRPGVKRNEKIYEQRNQQENEQSVASSQTYSLAR PVRTGLQMDAASNKSFERKNKLLFSHLEGPESPRYQNFYKGSRRESDAAYVDPIPTDYYNWGCF QKPPEDNDSNSYENVLICKPSTPESGTEESEDYQNSVSILQWRESKRTMGARTSPSGSPDEEPD YVNGDVATTEKI hide sequence

RefSeq Acc Id:	XP_006249222 ⟸ XM_006249160
- Peptide Label:	isoform X3
- UniProtKB:	G3V8Z1 (UniProtKB/TrEMBL)
- Sequence:	show sequence MSAELELLWPLSGLLLLLLLGTTAWLCVQCSRPGVKRNEKIYEQRNQQENEQSVASSQTYSLAR PVRTGLQMDAASNKSFERKNKLLFSHLEGPESPRYQNFYKGSRRESDAAYVDPIPTDYYNWGCF QKPPEDNDSNSYENVLICKPSTPESGTEESEDYQNSVSILQWRESKRTMGARTSPSGSPDEEPD YVNGDVATTEKI hide sequence

RefSeq Acc Id:	XP_017453848 ⟸ XM_017598359
- Peptide Label:	isoform X4
- Sequence:	show sequence MSAELELLWPLSGLLLLLLLGTTAWLCVQCSRPGVKRNEKIYEQRNQQENEQSVASSQTYSLAR PVRTGLQMDAASNKSFERKNKLLFSHLEGSRRESDAAYVDPIPTDYYNWGCFQKPPEDNDSNSY ENVLICKPSTPESGTEESEDYQNSVSILQWRESKRTMGARTSPSGSPDEEPDYVNGDVATTEKI hide sequence

RefSeq Acc Id:

XP_017453846 ⟸ XM_017598357

- Peptide Label:

isoform X1

- Sequence:

show sequence

MFLPSGLSFLSPGITDLCHHTQLTRTLSVTGSWKGQPGGVTKGRRGSRLQPSPTAPPEFRDTSY
AISVLAGVKRNEKIYEQRNQQENEQSVASSQTYSLARPVRTGLQMDAASNKSFERKNKLLFSHL
EGPESPRYQNFYKGSRRESDAAYVDPIPTDYYNWGCFQKPPEDNDSNSYENVLICKPSTPESGT
EESEDYQNSVSILQWRESKRTMGARTSPSGSPDEEPDYVNGDVATTEKI

hide sequence

RefSeq Acc Id:

XP_017453847 ⟸ XM_017598358

- Peptide Label:

isoform X2

- Sequence:

show sequence

MFLPSGLSFLSPGITDLCHHTQLTRTLSVTGSWKGQPGGVTKGRRGSRLQPSPTAPPEFRDTSY
AISVLAGVKRNEKIYEQRNQQENEQSVASSQTYSLARPVRTGLQMDAASNKSFERKNKLLFSHL
EGSRRESDAAYVDPIPTDYYNWGCFQKPPEDNDSNSYENVLICKPSTPESGTEESEDYQNSVSI
LQWRESKRTMGARTSPSGSPDEEPDYVNGDVATTEKI

hide sequence

RefSeq Acc Id:

ENSRNOP00000031304 ⟸ ENSRNOT00000034629

RefSeq Acc Id:	XP_038945460 ⟸ XM_039089532
- Peptide Label:	isoform X4

RefSeq Acc Id:	XP_038945461 ⟸ XM_039089533
- Peptide Label:	isoform X5

RefSeq Acc Id:	XP_038945459 ⟸ XM_039089531
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038945462 ⟸ XM_039089534
- Peptide Label:	isoform X6

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Strain Variation

Strain Sequence Variants (Rnor 6.0)

ACI/EurMcwi (MCW)

Visual

CSV

TAB

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

ACI/EurMcwi (RGD)

Visual

CSV

TAB

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

ACI/N (MCW)

Visual

CSV

TAB

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

BBDP/Wor (RGD)

Visual

CSV

TAB

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

BN/SsN (MCW)

Visual

CSV

TAB

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Buf/N (MCW)

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CSV

TAB

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

COP/CrCrl (MCW & UW)

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CSV

TAB

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob) University of Wisconsin (Dr. James Shull)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Charles River Laboratories
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)

F344/NCrl (RGD)

Visual

CSV

TAB

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

F344/NRrrc (MCW)

Visual

CSV

TAB

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

FHH/EurMcwi (MCW)

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CSV

TAB

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

FHH/EurMcwi (RGD)

Visual

CSV

TAB

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

FHL/EurMcwi (MCW)

Visual

CSV

TAB

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

FHL/EurMcwi (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

GH/OmrMcwi (MCW)

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CSV

TAB

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

GK/Ox (RGD)

Visual

CSV

TAB

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LE/Stm (RGD)

Visual

CSV

TAB

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LEW/Crl (RGD)

Visual

CSV

TAB

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LEW/NCrlBR (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LH/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LL/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LN/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

M520/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

MHS/Gib (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

MNS/Gib (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

MR/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

SBH/Ygl (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	SBH/Ygl sequenced by MCW

SBH/Ygl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SBN/Ygl (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	SBN/Ygl sequenced by MCW

SBN/Ygl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SHR/NHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SHRSP/Gcrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SR/JrHsd (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Harlan Laboratories
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

SR/JrHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SS/Jr (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SS/JrHsdMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

SS/JrHsdMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WAG/Rij (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/Gcrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

WKY/NCrl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/NHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WN/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:631397	AgrOrtholog
Ensembl Genes	ENSRNOG00000021856	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000031304	ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000034629	ENTREZGENE, UniProtKB/TrEMBL
InterPro	LAT2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:317676	UniProtKB/Swiss-Prot
NCBI Gene	317676	ENTREZGENE
PANTHER	PTHR15646	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	LAT2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Lat2	PhenoGen
UniProt	G3V8Z1	ENTREZGENE, UniProtKB/TrEMBL
	NTAL_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2005-11-17	Lat2	linker for activation of T cells family, member 2			Symbol and Name updated	1299863	APPROVED
2004-12-14	Wbscr5	Williams-Beuren syndrome chromosome region 5 homolog (human)			Symbol and Name status set to approved	1299863	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar