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Gene: Kmt5a (lysine methyltransferase 5A) Rattus norvegicus
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Symbol: Kmt5a
Name: lysine methyltransferase 5A
Description: Predicted to have histone-lysine N-methyltransferase activity; p53 binding activity; and transcription corepressor activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II; peptidyl-lysine monomethylation; and regulation of DNA damage response, signal transduction by p53 class mediator. Predicted to localize to the cytosol and nucleoplasm. Orthologous to human KMT5A (lysine methyltransferase 5A); PARTICIPATES IN methionine cycle/metabolic pathway; lysine degradation pathway; INTERACTS WITH diuron; ketamine; tetrachloromethane.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: histone methyltransferase Pr-set7/Set8; histone-lysine N-methyltransferase SETD8; LOC689820; lysine (K)-specific methyltransferase 5A; N-lysine methyltransferase KMT5A; N-lysine methyltransferase SETD8; Pr-set7; RGD1305893; SET domain containing (lysine methyltransferase) 8; SET domain-containing 8; Setd8; similar to SET domain-containing protein
Orthologs:
Homo sapiens (human) : KMT5A (lysine methyltransferase 5A)  HGNC  Alliance
Mus musculus (house mouse) : Kmt5a (lysine methyltransferase 5A)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Kmt5a (lysine methyltransferase 5A)
Pan paniscus (bonobo/pygmy chimpanzee) : KMT5A (lysine methyltransferase 5A)
Canis lupus familiaris (dog) : KMT5A (lysine methyltransferase 5A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Kmt5a (lysine methyltransferase 5A)
Sus scrofa (pig) : KMT5A (lysine methyltransferase 5A)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01237,558,150 - 37,581,183 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1237,559,770 - 37,574,750 (-)Ensembl
Rnor_5.01239,428,363 - 39,452,079 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41233,254,018 - 33,270,657 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1233,829,691 - 33,843,975 (-)NCBICelera
Cytogenetic Map12q15NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Kmt5a
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1587560
Created: 2006-11-19
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.