Pilrb-ps6 (paired immunoglobin-like type 2 receptor beta, pseudogene 6) - Rat Genome Database

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Gene: Pilrb-ps6 (paired immunoglobin-like type 2 receptor beta, pseudogene 6) Rattus norvegicus
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Symbol: Pilrb-ps6
Name: paired immunoglobin-like type 2 receptor beta, pseudogene 6
RGD ID: 1560262
Description: Predicted to enable MHC class I protein binding activity. Predicted to be located in cell periphery and membrane. Orthologous to human PILRA (paired immunoglobin like type 2 receptor alpha); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; bisphenol A.
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ENSRNOG00000064228; LOC501825; LOC685146; paired immunoglobulin-like type 2 receptor beta; RGD1560262; similar to cell surface receptor FDFACT; similar to paired immunoglobin-like type 2 receptor beta
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81224,305,306 - 24,335,088 (-)NCBIGRCr8
mRatBN7.21218,609,055 - 18,630,916 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1218,601,158 - 18,651,608 (-)NCBImRatBN7.2 Ensembl
mRatBN7.2 Ensembl1218,601,158 - 18,651,608 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.01220,282,072 - 20,300,904 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01222,332,264 - 22,353,100 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41220,180,880 - 20,183,996 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Cytogenetic Map12q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pilrb-ps6Rat17beta-estradiol multiple interactionsEXP 6480464[estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of PILRB-PS6 mRNACTDPMID:32741896
Pilrb-ps6Rat17beta-estradiol 3-benzoate multiple interactionsEXP 6480464[estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of PILRB-PS6 mRNACTDPMID:32741896
Pilrb-ps6Ratbisphenol A decreases expressionEXP 6480464bisphenol A results in decreased expression of PILRB-PS6 mRNACTDPMID:25181051
Pilrb-ps6Rattestosterone multiple interactionsEXP 6480464[estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of PILRB-PS6 mRNACTDPMID:32741896


Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pilrb-ps6Ratcell periphery located_inIEAARBA:ARBA000274431600115GO_REF:0000117UniProtGO_REF:0000117
Pilrb-ps6Ratmembrane located_inIEAARBA:ARBA000287631600115GO_REF:0000117UniProtGO_REF:0000117
Pilrb-ps6Ratmembrane located_inIEAUniProtKB-KW:KW-04721600115GO_REF:0000043UniProtGO_REF:0000043
Pilrb-ps6Ratmembrane located_inIEAUniProtKB-SubCell:SL-01621600115GO_REF:0000044UniProtGO_REF:0000044

Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pilrb-ps6RatMHC class I protein binding enablesIBAMGI:2450532 and PANTHER:PTN0003994881600115GO_REF:0000033GO_CentralGO_REF:0000033


#
Reference Title
Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions


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Variants in Pilrb-ps6
325 total Variants

1 to 10 of 48 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
2312418Kidm41Kidney mass QTL 413.70.0001kidney mass (VT:0002707)single kidney wet weight to body weight ratio (CMO:0000622)12119611090Rat
61443Btemp2Thermal response to stress QTL 23.30.000094body temperature trait (VT:0005535)core body temperature (CMO:0001036)121502518320794014Rat
8552964Pigfal17Plasma insulin-like growth factor 1 level QTL 173.5blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449546669029Rat
7411641Foco19Food consumption QTL 1927.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12556449546669029Rat
1549912Bp268Blood pressure QTL 268arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)101318273646669029Rat
2302060Pia37Pristane induced arthritis QTL 376.10.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)121319815746669029Rat
9590147Scort7Serum corticosterone level QTL 713.610.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)12142110980Rat
1641928Alcrsp5Alcohol response QTL 5response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)121281238546669029Rat
8552912Pigfal6Plasma insulin-like growth factor 1 level QTL 65blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449846669029Rat
1549829Scl48Serum cholesterol level QTL 485blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)12960327746669029Rat

1 to 10 of 48 rows






Ensembl Acc Id: ENSRNOT00000098960   ⟹   ENSRNOP00000095350
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1218,608,495 - 18,633,640 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000103398   ⟹   ENSRNOP00000083205
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1218,609,977 - 18,632,225 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000109195   ⟹   ENSRNOP00000095997
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1218,601,158 - 18,651,608 (-)Ensembl
RefSeq Acc Id: XM_063271771   ⟹   XP_063127841
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81224,305,306 - 24,335,088 (-)NCBI
RefSeq Acc Id: XM_063271772   ⟹   XP_063127842
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81224,326,173 - 24,335,084 (-)NCBI
Protein RefSeqs XP_063127841 (Get FASTA)   NCBI Sequence Viewer  
  XP_063127842 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000083205.1
  ENSRNOP00000095350.1
  ENSRNOP00000095997.1
Ensembl Acc Id: ENSRNOP00000095997   ⟸   ENSRNOT00000109195
Ensembl Acc Id: ENSRNOP00000083205   ⟸   ENSRNOT00000103398
Ensembl Acc Id: ENSRNOP00000095350   ⟸   ENSRNOT00000098960
RefSeq Acc Id: XP_063127841   ⟸   XM_063271771
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063127842   ⟸   XM_063271772
- Peptide Label: isoform X2


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen



1 to 18 of 18 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-19738 BioCyc
Ensembl Genes ENSRNOG00000064228 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000098960.1 UniProtKB/TrEMBL
  ENSRNOT00000103398.1 UniProtKB/TrEMBL
  ENSRNOT00000109195.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
InterPro Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Immunoregulatory_rcpt-like UniProtKB/TrEMBL
NCBI Gene Pilrb-ps6 ENTREZGENE
PANTHER PAIRED IMMUNOGLOBULIN-LIKE TYPE 2 RECEPTOR UniProtKB/TrEMBL
  PAIRED IMMUNOGLOBULIN-LIKE TYPE 2 RECEPTOR BETA-RELATED UniProtKB/TrEMBL
PhenoGen Pilrb-ps6 PhenoGen
RatGTEx ENSRNOG00000064228 RatGTEx
Superfamily-SCOP SSF48726 UniProtKB/TrEMBL
UniProt A0A8I5ZW39_RAT UniProtKB/TrEMBL
  A0A8I6AMG8_RAT UniProtKB/TrEMBL
  A0A8I6B3L3_RAT UniProtKB/TrEMBL
1 to 18 of 18 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-06-10 Pilrb-ps6  paired immunoglobin-like type 2 receptor beta, pseudogene 6  RGD1560262  similar to cell surface receptor FDFACT  Symbol and Name Changed 1299863 APPROVED
2022-06-02 RGD1560262  similar to cell surface receptor FDFACT  ENSRNOG00000064228    Data merged from RGD:150344633 737654 PROVISIONAL
2021-08-31 ENSRNOG00000064228        Symbol and Name status set to provisional 45752 PROVISIONAL
2015-07-29 RGD1560262  similar to cell surface receptor FDFACT  LOC685146  similar to paired immunoglobin-like type 2 receptor beta  Data merged from RGD:1597737 737654 PROVISIONAL
2012-07-02 RGD1560262  similar to cell surface receptor FDFACT  LOC685262  similar to paired immunoglobin-like type 2 receptor beta  Data merged from RGD:1596435 1643240 APPROVED
2008-04-30 RGD1560262  similar to cell surface receptor FDFACT   RGD1560262_predicted  similar to cell surface receptor FDFACT (predicted)  'predicted' is removed 2292626 APPROVED
2006-11-20 LOC685146  similar to paired immunoglobin-like type 2 receptor beta      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-11-20 LOC685262  similar to paired immunoglobin-like type 2 receptor beta      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-03-07 RGD1560262_predicted  similar to cell surface receptor FDFACT (predicted)  LOC501825  similar to cell surface receptor FDFACT  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC501825  similar to cell surface receptor FDFACT      Symbol and Name status set to provisional 70820 PROVISIONAL