Predicted to enable procollagen galactosyltransferase activity; procollagen glucosyltransferase activity; and procollagen-lysine 5-dioxygenase activity. Involved in cellular response to hormone stimulus. Predicted to be located in collagen-containing extracellular matrix; extracellular space; and trans-Golgi network. Predicted to be active in endoplasmic reticulum. Biomarker of hypothyroidism. Orthologous to human PLOD3 (procollagen-lysine,2-oxoglutarate 5-dioxygenase 3); PARTICIPATES IN lysine degradation pathway; O-linked glycan biosynthetic pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; aconitine.
bone protein I (BP-I); LH3; lysyl hydroxylase 3; MGC93055; multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3; procollagen-lysine,2-oxoglutarate 5-dioxygenase 3
[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of PLOD3 mRNA, Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to PLOD3 promoter]
[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of PLOD3 gene more ...
[Clofibrate co-treated with Acetaminophen] affects the expression of PLOD3 mRNA, PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of PLOD3 mRNA]
[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of PLOD3 gene more ...
[Clofibrate co-treated with Acetaminophen] affects the expression of PLOD3 mRNA, PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of PLOD3 mRNA]
Differential expression of procollagen lysine 2-oxoglutarate 5-deoxygenase and matrix metalloproteinase isoforms in hypothyroid rat ovary and disintegration of extracellular matrix.