PLOD3 (procollagen-lysine,2-oxoglutarate 5-dioxygenase 3) - Rat Genome Database

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Gene: PLOD3 (procollagen-lysine,2-oxoglutarate 5-dioxygenase 3) Chlorocebus sabaeus
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Symbol: PLOD3
Name: procollagen-lysine,2-oxoglutarate 5-dioxygenase 3
RGD ID: 18415812
Description: ENCODES a protein that exhibits small molecule binding (ortholog); INVOLVED IN basement membrane assembly (ortholog); cellular response to hormone stimulus (ortholog); collagen fibril organization (ortholog); ASSOCIATED WITH Bone Fragility with Contractures, Arterial Rupture, and Deafness (ortholog); Cerebral Hemorrhage (ortholog); genetic disease (ortholog); FOUND IN collagen-containing extracellular matrix (inferred); endoplasmic reticulum (inferred); endoplasmic reticulum membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12811,962,394 - 11,974,206 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2811,962,286 - 11,975,228 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660704,378,287 - 4,390,520 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
PLOD3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12811,962,394 - 11,974,206 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2811,962,286 - 11,975,228 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660704,378,287 - 4,390,520 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
PLOD3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387101,205,984 - 101,217,581 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7101,205,977 - 101,218,420 (-)EnsemblGRCh38hg38GRCh38
GRCh377100,849,265 - 100,860,862 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 367100,635,978 - 100,647,731 (-)NCBINCBI36Build 36hg18NCBI36
Build 347100,442,700 - 100,454,303NCBI
Celera795,858,417 - 95,870,169 (-)NCBICelera
Cytogenetic Map7q22.1NCBI
HuRef795,442,117 - 95,454,228 (-)NCBIHuRef
CHM1_17100,779,662 - 100,791,414 (-)NCBICHM1_1
T2T-CHM13v2.07102,529,447 - 102,541,882 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v27100,207,645 - 100,219,398 (-)NCBI
Plod3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395137,015,873 - 137,025,500 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5137,015,873 - 137,025,502 (+)EnsemblGRCm39 Ensembl
GRCm385136,987,019 - 136,996,646 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5136,987,019 - 136,996,648 (+)EnsemblGRCm38mm10GRCm38
MGSCv375137,462,889 - 137,472,516 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365137,271,649 - 137,281,166 (+)NCBIMGSCv36mm8
Celera5134,003,006 - 134,012,645 (+)NCBICelera
Cytogenetic Map5G2NCBI
cM Map576.09NCBI
Plod3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81225,313,070 - 25,323,631 (-)NCBIGRCr8
mRatBN7.21219,676,384 - 19,686,945 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1219,676,386 - 19,686,960 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1220,814,848 - 20,825,421 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01221,427,553 - 21,438,126 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01220,492,753 - 20,503,314 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01222,716,421 - 22,726,982 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1222,716,423 - 22,726,982 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01224,728,205 - 24,738,766 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41220,856,527 - 20,867,088 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11220,846,399 - 20,856,690 (+)NCBI
Celera1221,452,299 - 21,462,860 (-)NCBICelera
Cytogenetic Map12q12NCBI
Plod3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545616,082,437 - 16,093,389 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495545616,082,424 - 16,090,773 (+)NCBIChiLan1.0ChiLan1.0
PLOD3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26119,219,216 - 119,230,857 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan17167,483,838 - 167,495,393 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0793,347,335 - 93,358,921 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17106,587,858 - 106,599,605 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7106,587,858 - 106,599,605 (-)Ensemblpanpan1.1panPan2
PLOD3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.168,664,135 - 8,671,637 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl68,664,358 - 8,671,620 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha610,361,502 - 10,368,957 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.068,483,656 - 8,491,120 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl68,483,333 - 8,491,117 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.168,443,884 - 8,451,311 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.068,414,481 - 8,421,939 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.068,579,093 - 8,586,540 (+)NCBIUU_Cfam_GSD_1.0
Plod3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344132,939,235 - 132,946,261 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365431,090,253 - 1,097,301 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365431,090,268 - 1,097,170 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PLOD3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl38,911,791 - 8,919,516 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.138,911,787 - 8,919,525 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Plod3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474016,074,141 - 16,082,223 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474016,074,027 - 16,082,139 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression

ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
76 36 20 36 36 60 20

Sequence


Ensembl Acc Id: ENSCSAT00000016120   ⟹   ENSCSAP00000014042
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl2811,962,286 - 11,975,228 (+)Ensembl
RefSeq Acc Id: XM_008018465   ⟹   XP_008016656
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12811,962,394 - 11,974,206 (+)NCBI
Vero_WHO_p1.0NW_0236660704,378,287 - 4,390,520 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008018466   ⟹   XP_008016657
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12811,962,408 - 11,974,206 (+)NCBI
Vero_WHO_p1.0NW_0236660704,378,294 - 4,390,361 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_008016656 (Get FASTA)   NCBI Sequence Viewer  
  XP_008016657 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000014042.1
RefSeq Acc Id: XP_008016656   ⟸   XM_008018465
- Peptide Label: isoform X1
- UniProtKB: A0A0D9RZK3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_008016657   ⟸   XM_008018466
- Peptide Label: isoform X2
- UniProtKB: A0A0D9RZK3 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCSAP00000014042   ⟸   ENSCSAT00000016120


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000018025 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000016120.1 UniProtKB/TrEMBL
Gene3D-CATH q2cbj1_9rhob like domain UniProtKB/TrEMBL
InterPro Collagen_mod_GT25 UniProtKB/TrEMBL
  IPNS-like_FE2OG_OXY UniProtKB/TrEMBL
  Nucleotide-diphossugar_trans UniProtKB/TrEMBL
  Oxoglu/Fe-dep_dioxygenase UniProtKB/TrEMBL
  Pro_4_hyd_alph UniProtKB/TrEMBL
  Procol_lys_dOase UniProtKB/TrEMBL
KEGG Report csab:103246688 UniProtKB/TrEMBL
NCBI Gene PLOD3 ENTREZGENE
PANTHER MULTIFUNCTIONAL PROCOLLAGEN LYSINE HYDROXYLASE AND GLYCOSYLTRANSFERASE LH3 UniProtKB/TrEMBL
  PROCOLLAGEN-LYSINE,2-OXOGLUTARATE 5-DIOXYGENASE/GLYCOSYLTRANSFERASE 25 FAMILY MEMBER UniProtKB/TrEMBL
Pfam 2OG-FeII_Oxy UniProtKB/TrEMBL
PROSITE FE2OG_OXY UniProtKB/TrEMBL
  LYS_HYDROXYLASE UniProtKB/TrEMBL
SMART P4Hc UniProtKB/TrEMBL
Superfamily-SCOP SSF53448 UniProtKB/TrEMBL
UniProt A0A0D9RZK3 ENTREZGENE, UniProtKB/TrEMBL