Insr (insulin receptor) - Rat Genome Database

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Gene: Insr (insulin receptor) Rattus norvegicus
Analyze
Symbol: Insr
Name: insulin receptor
RGD ID: 2917
Description: Enables several functions, including enzyme binding activity; insulin binding activity; and insulin receptor substrate binding activity. Involved in several processes, including animal organ development; neuron projection organization; and regulation of glucose metabolic process. Located in several cellular components, including dendrite membrane; neuronal cell body membrane; and yolk. Colocalizes with dendrite and neuronal cell body. Used to study chronic kidney disease; diabetic neuropathy; fatty liver disease (multiple); hepatocellular carcinoma; and type 2 diabetes mellitus. Biomarker of several diseases, including diabetes mellitus (multiple); fatty liver disease (multiple); hepatic encephalopathy; hepatocellular carcinoma; and short bowel syndrome. Human ortholog(s) of this gene implicated in Donohue syndrome; diabetes mellitus (multiple); familial hyperinsulinemic hypoglycemia 5; and reproductive organ cancer (multiple). Orthologous to human INSR (insulin receptor); PARTICIPATES IN altered leptin system pathway; insulin signaling pathway; phosphatidylinositol 3-kinase-Akt signaling pathway; INTERACTS WITH (+)-catechin; (3,4-dihydroxyphenyl)acetic acid; (S)-nicotine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: insulin receptor preproprotein; IR
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Is Marker For: Strains:   LEW-Tg(H1/tetO-RNAi:Insr)87Hrjb   LEW-Tg(H1/tetO-RNAi:Insr)4Hrjb  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2121,193,193 - 1,330,976 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl121,197,100 - 1,330,883 (-)Ensembl
Rnor_6.0121,682,527 - 1,816,414 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl121,680,957 - 1,816,414 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0123,848,670 - 3,989,302 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4122,934,967 - 3,087,691 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1122,934,966 - 3,087,691 (+)NCBI
Celera123,053,590 - 3,185,991 (-)NCBICelera
Cytogenetic Map12p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-catechin  (EXP,ISO)
(3,4-dihydroxyphenyl)acetic acid  (EXP)
(S)-nicotine  (EXP)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
3,3',4,4'-tetrachlorobiphenyl  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3-chloropropane-1,2-diol  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide  (ISO)
9-cis,11-trans-octadecadienoic acid  (ISO)
9-cis-retinoic acid  (EXP)
acetamide  (EXP)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
AICA ribonucleotide  (ISO)
aldehydo-D-glucose  (EXP,ISO)
all-trans-retinoic acid  (EXP,ISO)
allopurinol  (EXP)
alloxan  (EXP)
anthra[1,9-cd]pyrazol-6(2H)-one  (EXP,ISO)
AP20187  (ISO)
aristolochic acid  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[e]pyrene  (ISO)
benzoic acid  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP,ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
caffeine  (EXP)
carbamazepine  (ISO)
carbon nanotube  (ISO)
choline  (EXP)
chromium atom  (ISO)
chromium(3+) trichloride  (EXP)
chromium(6+)  (EXP)
cobalt atom  (EXP)
copper atom  (ISO)
copper(0)  (ISO)
curcumin  (ISO)
cyclosporin A  (ISO)
D-glucose  (EXP,ISO)
dapagliflozin  (EXP)
DDT  (EXP)
decabromodiphenyl ether  (ISO)
dexamethasone  (ISO)
diclofenac  (ISO)
dioxygen  (EXP,ISO)
dipyridamole  (ISO)
doxorubicin  (ISO)
duvoglustat  (ISO)
endosulfan  (EXP)
ethanol  (EXP,ISO)
fructose  (EXP)
fulvestrant  (EXP)
glucose  (EXP,ISO)
hexachlorobenzene  (EXP,ISO)
hexadecanoic acid  (ISO)
hydrogen peroxide  (ISO)
indometacin  (EXP)
insulin  (EXP)
isoliquiritigenin  (ISO)
L-ascorbic acid  (EXP)
lead diacetate  (EXP)
leflunomide  (EXP)
linoleic acid  (ISO)
linsidomine  (ISO)
lovastatin  (EXP)
luteolin  (ISO)
magnesium atom  (ISO)
manganese atom  (EXP,ISO)
manganese(0)  (EXP,ISO)
manganese(II) chloride  (EXP)
melatonin  (EXP)
metformin  (ISO)
methamphetamine  (ISO)
methapyrilene  (EXP,ISO)
methotrexate  (ISO)
methoxychlor  (EXP)
methylglyoxal  (ISO)
methylmercury chloride  (ISO)
miconazole  (EXP)
molybdate  (EXP)
mono(2-ethylhexyl) phthalate  (EXP)
N-acetyl-L-cysteine  (ISO)
N-ethyl-N-nitrosourea  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-methyl-N-nitrosourea  (EXP)
N-nitrosodiethylamine  (EXP)
N-nitrosomorpholine  (EXP)
NAD zwitterion  (ISO)
NAD(+)  (ISO)
nickel atom  (EXP,ISO)
nicotine  (EXP)
nitrofen  (EXP)
oleanolic acid  (EXP)
oleic acid  (ISO)
orientin  (ISO)
ozone  (EXP)
paracetamol  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenylarsine oxide  (ISO)
phenytoin  (ISO)
picolinic acid  (EXP)
potassium chromate  (ISO)
progesterone  (EXP,ISO)
puerarin  (ISO)
quercetin  (EXP)
quercitrin  (ISO)
raffinose  (EXP,ISO)
rebaudioside A  (ISO)
resveratrol  (EXP,ISO)
rivastigmine  (EXP)
Rutamarin  (ISO)
rutin  (EXP)
SB 203580  (EXP)
sodium arsenite  (ISO)
Soman  (EXP)
steviol  (ISO)
stevioside  (ISO)
streptozocin  (EXP,ISO)
sulfasalazine  (ISO)
taurine  (EXP)
testosterone  (ISO)
tetrachloroethene  (ISO)
thiazolidines  (ISO)
titanium dioxide  (ISO)
tributylstannane  (ISO)
triclosan  (EXP)
triphenyl phosphate  (ISO)
Triptolide  (EXP)
troglitazone  (ISO)
urethane  (ISO)
valproic acid  (EXP,ISO)
vildagliptin  (EXP)
vitamin E  (EXP)
wortmannin  (EXP)
zinc atom  (EXP,ISO)
zinc dichloride  (ISO)
zinc(0)  (EXP,ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
activation of protein kinase activity  (ISO)
activation of protein kinase B activity  (IEA,ISO)
adrenal gland development  (IEA,ISO)
alternative mRNA splicing, via spliceosome  (IEP)
amyloid-beta clearance  (IMP)
animal organ morphogenesis  (IEA,ISO)
cellular response to growth factor stimulus  (IEA,ISO)
cellular response to insulin stimulus  (ISO)
cerebellum development  (IEP)
dendritic spine maintenance  (IGI)
embryonic liver development  (IEP)
epidermis development  (IEA,ISO)
exocrine pancreas development  (IEA,ISO)
fat cell differentiation  (IEP)
G protein-coupled receptor signaling pathway  (IEA,ISO)
glucose homeostasis  (IBA,IDA,IEA,ISO)
heart morphogenesis  (IEA,ISO)
hippocampus development  (IEP)
insulin receptor signaling pathway  (IDA,IEA,IEP,IMP,ISO)
liver development  (IEP)
liver regeneration  (IEP)
male gonad development  (IEA,ISO)
male sex determination  (IEA,ISO)
negative regulation of feeding behavior  (IMP)
negative regulation of gene expression  (IMP)
negative regulation of glycogen biosynthetic process  (IEP)
negative regulation of protein phosphorylation  (IMP)
negative regulation of transporter activity  (IMP)
neuron projection maintenance  (IGI)
peptidyl-tyrosine autophosphorylation  (IEA,ISO)
peptidyl-tyrosine phosphorylation  (IEA,IMP,ISO)
positive regulation of cell migration  (IEA,ISO)
positive regulation of cell population proliferation  (IEA,ISO)
positive regulation of developmental growth  (IEA,ISO)
positive regulation of glucose import  (IEA,ISO)
positive regulation of glycogen biosynthetic process  (IEA,ISO)
positive regulation of glycolytic process  (IEA,ISO)
positive regulation of glycoprotein biosynthetic process  (IMP)
positive regulation of kinase activity  (IBA)
positive regulation of MAP kinase activity  (IEA,ISO)
positive regulation of MAPK cascade  (IBA,ISO)
positive regulation of meiotic cell cycle  (IEA,ISO)
positive regulation of mitotic nuclear division  (IEA,ISO)
positive regulation of nitric oxide biosynthetic process  (IEA,ISO)
positive regulation of phosphatidylinositol 3-kinase signaling  (IBA)
positive regulation of phosphorylation  (IDA)
positive regulation of protein kinase B signaling  (IBA,IEA,ISO)
positive regulation of protein phosphorylation  (ISO)
positive regulation of protein-containing complex disassembly  (IGI)
positive regulation of receptor internalization  (IEA,ISO)
positive regulation of respiratory burst  (IEA,ISO)
positive regulation of transcription, DNA-templated  (IEA,ISO)
protein autophosphorylation  (IDA,IEA,IMP,ISO)
protein phosphorylation  (IDA,IEP)
receptor-mediated endocytosis  (IMP)
regulation of embryonic development  (IEA,ISO)
regulation of female gonad development  (IEA,ISO)
regulation of gluconeogenesis  (IEP)
regulation of hydrogen peroxide metabolic process  (IDA)
regulation of transcription, DNA-templated  (ISO)
response to activity  (IEP)
response to estradiol  (IEP)
response to ethanol  (IEP)
response to food  (IEP)
response to glucocorticoid  (IEP)
response to glucose  (IEP)
response to hormone  (IEP)
response to hypoxia  (IEP)
response to insulin  (IEP)
response to manganese ion  (IEP)
response to nutrient levels  (IDA,IEP)
response to organic substance  (IEP)
response to resveratrol  (IEP)
response to starvation  (IEP)
response to testosterone  (IEP)
response to tumor necrosis factor  (IMP)
response to vanadate(3-)  (IEP)
response to vitamin D  (IEP)
transformation of host cell by virus  (IEA)
transmembrane receptor protein tyrosine kinase signaling pathway  (IBA,IEA)
viral entry into host cell  (ISO)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
1. Aleem E, etal., Toxicol Pathol. 2011 Apr;39(3):524-43. doi: 10.1177/0192623310396905. Epub 2011 Mar 16.
2. Araujo EP, etal., FEBS Lett 2002 Nov 20;531(3):437-42.
3. Barbuio R, etal., J Endocrinol. 2007 Sep;194(3):539-50.
4. Belke DD, etal., J Clin Invest 2002 Mar;109(5):629-39.
5. Ben Lulu S, etal., Pediatr Surg Int. 2010 Jan;26(1):37-44. doi: 10.1007/s00383-009-2520-x.
6. Blondel O, etal., Am J Physiol. 1990 Mar;258(3 Pt 1):E459-67. doi: 10.1152/ajpendo.1990.258.3.E459.
7. Bluher M, etal., Dev Cell 2002 Jul;3(1):25-38.
8. Boutchueng-Djidjou M, etal., Mol Cell Proteomics. 2015 Apr;14(4):1079-92. doi: 10.1074/mcp.M114.047159. Epub 2015 Feb 16.
9. Breton C, etal., Am J Physiol Endocrinol Metab. 2009 Mar;296(3):E462-72. Epub 2008 Dec 16.
10. Caliendo AM and Patel MS, Arch Biochem Biophys. 1983 Dec;227(2):552-61. doi: 10.1016/0003-9861(83)90484-8.
11. Calle C, etal., BMC Mol Biol. 2008 Jul 18;9:65.
12. Chettouh H, etal., Cancer Res. 2013 Jul 1;73(13):3974-86. doi: 10.1158/0008-5472.CAN-12-3824. Epub 2013 Apr 30.
13. Colomiere M, etal., Eur J Endocrinol. 2009 Apr;160(4):567-78. Epub 2009 Jan 29.
14. Daya S, etal., Differentiation. 2007 Jun;75(5):360-70. Epub 2007 Feb 5.
15. de Borst MH, etal., Am J Physiol Renal Physiol. 2007 Jul;293(1):F428-37. Epub 2007 Apr 11.
16. De Felice FG, etal., Proc Natl Acad Sci U S A. 2009 Feb 10;106(6):1971-6. doi: 10.1073/pnas.0809158106. Epub 2009 Feb 2.
17. Deger A, etal., Biochem Biophys Res Commun. 1986 Mar 13;135(2):458-64.
18. Desbuquois B, etal., FEBS J. 2008 Sep;275(17):4363-77. Epub 2008 Jul 24.
19. Diaz LE, etal., Mol Hum Reprod. 2007 Aug;13(8):567-76. Epub 2007 Jun 6.
20. Diesel B, etal., Biochemistry. 2007 Feb 27;46(8):2146-55. Epub 2007 Feb 3.
21. Ding S, etal., Toxicol Sci. 2017 Oct 1;159(2):290-306. doi: 10.1093/toxsci/kfx093.
22. Dongiovanni P, etal., Clin Sci (Lond). 2017 Jun 7;131(12):1301-1315. doi: 10.1042/CS20170175. Print 2017 Jun 1.
23. Eisenberg ML, etal., Cell Physiol Biochem. 2005;15(1-4):51-8.
24. Evert M, etal., Cancer Res. 2004 Nov 1;64(21):8093-100.
25. Feres NH, etal., Nutrition. 2010 Apr;26(4):441-8. Epub 2009 Oct 31.
26. Fiory F, etal., Mol Cell Biol. 2005 Dec;25(24):10803-14.
27. Frittitta L, etal., Breast Cancer Res Treat. 1993;25(1):73-82.
28. Gan KX, etal., World J Gastroenterol. 2013 Mar 14;19(10):1572-81. doi: 10.3748/wjg.v19.i10.1572.
29. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
30. Gerena Y, etal., PLoS One. 2012;7(5):e37358. doi: 10.1371/journal.pone.0037358. Epub 2012 May 22.
31. Giddings SJ and Carnaghi LR, Mol Endocrinol. 1992 Oct;6(10):1665-72. doi: 10.1210/mend.6.10.1448116.
32. GOA data from the GO Consortium
33. Grillo CA, etal., Physiol Behav. 2007 Nov 23;92(4):691-701. Epub 2007 May 21.
34. Haghir H, etal., Metab Brain Dis. 2013 Sep;28(3):397-410. doi: 10.1007/s11011-013-9386-2. Epub 2013 Feb 10.
35. Hami J, etal., Brain Struct Funct. 2012 Apr;217(2):293-302. doi: 10.1007/s00429-011-0358-1. Epub 2011 Nov 1.
36. Hami J, etal., Brain Struct Funct. 2013 Jan;218(1):73-84. doi: 10.1007/s00429-011-0377-y. Epub 2012 Jan 13.
37. Herold MJ, etal., Proc Natl Acad Sci U S A. 2008 Nov 25;105(47):18507-12. Epub 2008 Nov 18.
38. Hers I, etal., Biochem J 2002 Dec 15;368(Pt 3):875-84.
39. Hirata AE, etal., Life Sci. 2003 Aug 1;73(11):1369-81.
40. Hunter SJ and Garvey WT, Am J Med. 1998 Oct;105(4):331-45.
41. Irani BG, etal., Endocrinology. 2007 Jan;148(1):310-6. Epub 2006 Oct 5.
42. Jacob AI, etal., J Mol Endocrinol. 2010 Mar;44(3):155-69. Epub 2009 Dec 1.
43. Kasus-Jacobi A, etal., J Biol Chem 1998 Oct 2;273(40):26026-35.
44. KEGG
45. Khamzina L, etal., Gastroenterology 2003 Aug;125(2):572-85.
46. Kim MH, etal., PLoS One. 2013 Jul 9;8(7):e67802. doi: 10.1371/journal.pone.0067802. Print 2013.
47. Kitamura T, etal., J Clin Invest 2004 Jan;113(2):209-19.
48. Koricanac G, etal., Acta Biol Hung. 2008 Mar;59(1):17-29.
49. Koricanac G, etal., J Steroid Biochem Mol Biol. 2008 Jan;108(1-2):109-16. Epub 2007 Sep 7.
50. Kotnik K, etal., PLoS ONE. 2009;4(4):e5124. Epub 2009 Apr 2.
51. Kou ZZ, etal., Pain Physician. 2013 Mar-Apr;16(2):E71-83.
52. Lester-Coll N, etal., J Alzheimers Dis. 2006 Mar;9(1):13-33.
53. Li H, etal., Spine. 2008 Oct 15;33(22):2394-402.
54. Limin T, etal., Alcohol. 2009 Feb;43(1):51-8.
55. Lin X, etal., Exp Ther Med. 2018 Jul;16(1):204-212. doi: 10.3892/etm.2018.6194. Epub 2018 May 18.
56. Liu H, etal., Eur J Pharmacol. 2009 Jan 14;602(2-3):277-82. Epub 2008 Nov 21.
57. Liu TJ, etal., J Endocrinol. 2007 Jan;192(1):149-58.
58. Long-Smith CM, etal., Neuromolecular Med. 2013 Mar;15(1):102-14. doi: 10.1007/s12017-012-8199-5. Epub 2012 Sep 21.
59. Lopez-Pastor AR, etal., Dis Model Mech. 2019 Feb 7;12(2). pii: dmm.036186. doi: 10.1242/dmm.036186.
60. Maegawa H, etal., Biochem Biophys Res Commun. 1996 Nov 1;228(1):122-7.
61. Mazibuko-Mbeje SE, etal., Int J Mol Sci. 2019 Feb 1;20(3). pii: ijms20030633. doi: 10.3390/ijms20030633.
62. Meakin PJ, etal., Nat Commun. 2018 Apr 3;9(1):1306. doi: 10.1038/s41467-018-03755-2.
63. MGD data from the GO Consortium
64. Michael MD, etal., Mol Cell 2000 Jul;6(1):87-97.
65. Mielke JG, etal., Neuroscience. 2006 Nov 17;143(1):165-73. Epub 2006 Sep 14.
66. Moloney AM, etal., Neurobiol Aging. 2010 Feb;31(2):224-43. doi: 10.1016/j.neurobiolaging.2008.04.002. Epub .
67. Mulligan AM, etal., Breast Cancer Res Treat. 2007 Nov;106(1):39-47. Epub 2007 Jan 13.
68. Munoz MC, etal., J Endocrinol. 2009 May;201(2):185-97. Epub 2009 Feb 27.
69. Murakami K, etal., Biochem Biophys Res Commun. 2011 May 27;409(1):34-9. doi: 10.1016/j.bbrc.2011.04.101. Epub 2011 Apr 28.
70. Murugan P, etal., J Biosci. 2008 Mar;33(1):63-72.
71. Muthusamy T, etal., Life Sci. 2007 Jul 26;81(7):534-42. Epub 2007 Jun 28.
72. NCBI rat LocusLink and RefSeq merged data July 26, 2002
73. Neuvians TP, etal., Neoplasia. 2005 May;7(5):446-56.
74. Obici S, etal., Nat Neurosci 2002 Jun;5(6):566-72.
75. Ofer P, etal., Mol Endocrinol. 2015 Dec;29(12):1694-707. doi: 10.1210/me.2015-1073. Epub 2015 Oct 9.
76. Oh YS, etal., Exp Mol Med. 2007 Jun 30;39(3):395-401.
77. Okamoto H, etal., J Clin Invest 2004 Jul;114(2):214-23.
78. OMIM Disease Annotation Pipeline
79. Pender C, etal., J Biol Chem 2002 Nov 15;277(46):43565-71.
80. Peterson SJ, etal., J Lipid Res. 2009 Mar 26.
81. Pipeline to import KEGG annotations from KEGG into RGD
82. Pipeline to import Pathway Interaction Database annotations from NCI into RGD
83. Pipeline to import SMPDB annotations from SMPDB into RGD
84. Qin B, etal., Atherosclerosis. 2012 Jun;222(2):409-16. doi: 10.1016/j.atherosclerosis.2012.03.033. Epub 2012 Apr 11.
85. RGD automated data pipeline
86. RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
87. RGD automated import pipeline for gene-chemical interactions
88. Rodrigues MA, etal., Hepatology. 2008 Nov;48(5):1621-31.
89. Samuel VT, etal., J Clin Invest. 2007 Mar;117(3):739-45. Epub 2007 Feb 22.
90. Seki N, etal., Horm Metab Res. 2008 Dec;40(12):833-7. Epub 2008 Oct 16.
91. Sherajee SJ, etal., Arterioscler Thromb Vasc Biol. 2012 Feb;32(2):257-63. doi: 10.1161/ATVBAHA.111.240697. Epub 2011 Dec 15.
92. Spasov AA, etal., Bull Exp Biol Med. 2007 Jul;144(1):46-8.
93. Storozhevykh TP, etal., BMC Neurosci. 2007 Oct 8;8:84.
94. Sugimoto K, etal., J Pain. 2008 Mar;9(3):237-45. Epub 2007 Dec 3.
95. Sun D, etal., Obes Surg. 2013 Nov;23(11):1734-42. doi: 10.1007/s11695-013-0985-0.
96. Szpirer C, etal., Mamm Genome 1997 Aug;8(8):586-8
97. Takahashi M, etal., Int J Oncol. 2005 Apr;26(4):923-31.
98. Temofonte N, etal., Diabetologia. 2009 Jan;52(1):60-4. Epub 2008 Oct 30.
99. Thyfault JP, etal., Am J Physiol Cell Physiol. 2007 Feb;292(2):C729-39. Epub 2006 Oct 18.
100. Tiwari S, etal., J Am Soc Nephrol. 2007 Oct;18(10):2661-71. Epub 2007 Sep 12.
101. Tornqvist HE, etal., J Biol Chem. 1988 Jan 5;263(1):350-9.
102. Tozzo E and Desbuquois B, Diabetes. 1992 Dec;41(12):1609-16. doi: 10.2337/diab.41.12.1609.
103. Venkateswaran V, etal., J Natl Cancer Inst. 2007 Dec 5;99(23):1793-800. Epub 2007 Nov 27.
104. Wang Q, etal., Mol Med Rep. 2015 Jan;11(1):151-8. doi: 10.3892/mmr.2014.2762. Epub 2014 Oct 23.
105. Wang X, etal., Mol Cell Endocrinol. 2015 Nov 15;416:57-69. doi: 10.1016/j.mce.2015.08.021. Epub 2015 Aug 20.
106. White MF, etal., J Biol Chem. 1984 Jan 10;259(1):255-64.
107. Yang Y, etal., Biomed Pharmacother. 2008 Jul 9.
108. Yao FF, etal., Zhonghua Gan Zang Bing Za Zhi. 2017 Dec 20;25(12):927-933. doi: 10.3760/cma.j.issn.1007-3418.2017.12.008.
109. Youngren JF Cell Mol Life Sci. 2007 Apr;64(7-8):873-91.
110. Zhang B, etal., Zhonghua Shao Shang Za Zhi 2002 Aug;18(4):220-2.
111. Zhang L, etal., J Transl Med. 2014 Aug 27;12:236. doi: 10.1186/s12967-014-0236-8.
112. Zhao WQ, etal., J Biol Chem. 2009 Jul 10;284(28):18742-53. doi: 10.1074/jbc.M109.011015. Epub 2009 Apr 30.
113. Zhou QG, etal., Am J Physiol Heart Circ Physiol. 2012 Nov 1;303(9):H1154-65. doi: 10.1152/ajpheart.00407.2012. Epub 2012 Aug 31.
Additional References at PubMed
PMID:1520270   PMID:1898103   PMID:2210055   PMID:2330003   PMID:3518947   PMID:6849137   PMID:7493946   PMID:7537849   PMID:7556070   PMID:7559478   PMID:7693131   PMID:8276809  
PMID:8440175   PMID:8452530   PMID:8496180   PMID:9092559   PMID:9415395   PMID:9447983   PMID:9819385   PMID:9832615   PMID:10100151   PMID:10747347   PMID:11500939   PMID:11750072  
PMID:11939351   PMID:12079879   PMID:12101187   PMID:12138094   PMID:12477932   PMID:12488434   PMID:12821126   PMID:12881524   PMID:14506612   PMID:14562105   PMID:14628051   PMID:14644152  
PMID:15069075   PMID:15134438   PMID:15134829   PMID:15182363   PMID:15337529   PMID:15375597   PMID:16052330   PMID:16246733   PMID:16353347   PMID:16513830   PMID:16803852   PMID:16839253  
PMID:16921752   PMID:16957736   PMID:17001305   PMID:17299086   PMID:17555093   PMID:17925406   PMID:17974582   PMID:18278056   PMID:18313837   PMID:18492485   PMID:18679562   PMID:18713797  
PMID:18752648   PMID:19345745   PMID:19386987   PMID:19554259   PMID:19575708   PMID:19744960   PMID:19953342   PMID:20032056   PMID:20100694   PMID:20149705   PMID:20443665   PMID:20455999  
PMID:20458337   PMID:20868513   PMID:21195590   PMID:21211393   PMID:21301931   PMID:21443795   PMID:21683721   PMID:21828334   PMID:22207502   PMID:22248283   PMID:22564491   PMID:22611938  
PMID:22871113   PMID:22996137   PMID:23059533   PMID:23066017   PMID:23300479   PMID:23322319   PMID:23382219   PMID:23592917   PMID:23839970   PMID:23906066   PMID:24023699   PMID:24023717  
PMID:24078630   PMID:24130215   PMID:24462861   PMID:24963636   PMID:25401701   PMID:26853939   PMID:27930980   PMID:28470423   PMID:28495883   PMID:29215540   PMID:29289466   PMID:29412813  
PMID:29955950   PMID:33513940   PMID:33915127   PMID:34022289  


Genomics

Comparative Map Data
Insr
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2121,193,193 - 1,330,976 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl121,197,100 - 1,330,883 (-)Ensembl
Rnor_6.0121,682,527 - 1,816,414 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl121,680,957 - 1,816,414 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0123,848,670 - 3,989,302 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4122,934,967 - 3,087,691 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1122,934,966 - 3,087,691 (+)NCBI
Celera123,053,590 - 3,185,991 (-)NCBICelera
Cytogenetic Map12p12NCBI
INSR
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl197,112,255 - 7,294,414 (-)EnsemblGRCh38hg38GRCh38
GRCh38197,112,257 - 7,294,414 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37197,112,276 - 7,294,425 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36197,063,266 - 7,245,011 (-)NCBINCBI36hg18NCBI36
Build 34197,067,637 - 7,245,011NCBI
Celera197,049,684 - 7,205,258 (-)NCBI
Cytogenetic Map19p13.2NCBI
HuRef196,846,024 - 7,028,322 (-)NCBIHuRef
CHM1_1197,111,894 - 7,294,424 (-)NCBICHM1_1
Insr
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3983,200,922 - 3,329,649 (-)NCBIGRCm39mm39
GRCm39 Ensembl83,172,061 - 3,329,617 (-)Ensembl
GRCm3883,150,922 - 3,279,649 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl83,122,061 - 3,279,617 (-)EnsemblGRCm38mm10GRCm38
MGSCv3783,150,922 - 3,279,617 (-)NCBIGRCm37mm9NCBIm37
MGSCv3683,155,669 - 3,279,176 (-)NCBImm8
Celera83,375,321 - 3,505,728 (-)NCBICelera
Cytogenetic Map8A1.1NCBI
cM Map81.82NCBI
Insr
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555631,867,400 - 2,009,149 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555631,867,400 - 2,011,845 (+)NCBIChiLan1.0ChiLan1.0
INSR
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1197,255,444 - 7,411,916 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl197,260,246 - 7,414,889 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0196,393,407 - 6,578,234 (-)NCBIMhudiblu_PPA_v0panPan3
INSR
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12052,017,261 - 52,136,061 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2052,021,887 - 52,136,046 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2051,822,227 - 51,957,301 (-)NCBI
ROS_Cfam_1.02052,547,342 - 52,682,557 (-)NCBI
UMICH_Zoey_3.12051,751,620 - 51,886,677 (-)NCBI
UNSW_CanFamBas_1.02052,194,853 - 52,330,054 (-)NCBI
UU_Cfam_GSD_1.02052,425,027 - 52,560,283 (-)NCBI
Insr
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118213,335,383 - 213,489,477 (+)NCBI
SpeTri2.0NW_0049365884,345,306 - 4,453,380 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
INSR
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl271,797,204 - 71,936,139 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1271,797,209 - 71,939,923 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2272,388,108 - 72,420,533 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap2q11-q21NCBI
INSR
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.166,625,951 - 6,803,610 (-)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl66,630,777 - 6,803,592 (-)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660811,077,953 - 1,266,880 (+)NCBIVero_WHO_p1.0
Insr
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624828345,135 - 485,856 (-)NCBIHetGla_female_1.0hetGla2

Position Markers
D12Rat56  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2121,247,864 - 1,248,029 (+)MAPPERmRatBN7.2
Rnor_6.0121,733,779 - 1,733,943NCBIRnor6.0
Rnor_5.0123,906,310 - 3,906,474UniSTSRnor5.0
RGSC_v3.4123,017,038 - 3,017,201RGDRGSC3.4
RGSC_v3.4123,017,039 - 3,017,203UniSTSRGSC3.4
RGSC_v3.1123,017,038 - 3,017,201RGD
Celera123,103,583 - 3,103,747UniSTS
SHRSP x BN Map122.17UniSTS
SHRSP x BN Map122.17RGD
Cytogenetic Map12q12UniSTS
D12Arb12  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2121,196,839 - 1,197,008 (+)MAPPERmRatBN7.2
Rnor_6.0121,682,267 - 1,682,435NCBIRnor6.0
Rnor_5.0123,852,317 - 3,852,485UniSTSRnor5.0
RGSC_v3.4123,087,782 - 3,087,951RGDRGSC3.4
RGSC_v3.4123,087,783 - 3,087,951UniSTSRGSC3.4
RGSC_v3.1123,087,782 - 3,087,951RGD
Celera123,053,330 - 3,053,498UniSTS
Cytogenetic Map12q12UniSTS
D12Wox28  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2121,196,848 - 1,197,057 (+)MAPPERmRatBN7.2
Rnor_6.0121,682,276 - 1,682,484NCBIRnor6.0
Rnor_5.0123,852,326 - 3,852,534UniSTSRnor5.0
RGSC_v3.4123,087,734 - 3,087,942UniSTSRGSC3.4
Celera123,053,339 - 3,053,547UniSTS
Cytogenetic Map12q12UniSTS
D12Wox26  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2121,201,555 - 1,201,778 (+)MAPPERmRatBN7.2
Rnor_6.0121,686,983 - 1,687,205NCBIRnor6.0
Rnor_5.0123,857,033 - 3,857,255UniSTSRnor5.0
RGSC_v3.4123,083,013 - 3,083,235UniSTSRGSC3.4
Celera123,058,046 - 3,058,258UniSTS
Cytogenetic Map12q12UniSTS
PMC152262P1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2121,307,815 - 1,307,954 (+)MAPPERmRatBN7.2
Rnor_6.0121,793,684 - 1,793,822NCBIRnor6.0
Rnor_5.0123,966,395 - 3,966,533UniSTSRnor5.0
RGSC_v3.4122,957,559 - 2,957,697UniSTSRGSC3.4
Celera123,163,279 - 3,163,417UniSTS
Cytogenetic Map12q12UniSTS
BF390301  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2121,270,183 - 1,270,340 (+)MAPPERmRatBN7.2
Rnor_6.0121,756,051 - 1,756,207NCBIRnor6.0
Rnor_5.0123,928,762 - 3,928,918UniSTSRnor5.0
RGSC_v3.4122,995,176 - 2,995,332UniSTSRGSC3.4
Celera123,125,753 - 3,125,909UniSTS
Cytogenetic Map12q12UniSTS
AU048528  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2121,268,402 - 1,268,538 (+)MAPPERmRatBN7.2
Rnor_6.0121,754,270 - 1,754,405NCBIRnor6.0
Rnor_5.0123,926,981 - 3,927,116UniSTSRnor5.0
RGSC_v3.4122,996,978 - 2,997,113UniSTSRGSC3.4
Celera123,123,972 - 3,124,107UniSTS
Cytogenetic Map12q12UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300174Bw15Body weight QTL 152.93body mass (VT:0001259)body weight loss (CMO:0001399)1219318387Rat
2312418Kidm41Kidney mass QTL 413.70.0001kidney mass (VT:0002707)single kidney wet weight to body weight ratio (CMO:0000622)12119611090Rat
10755457Coatc14Coat color QTL 140.01759coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)12122591684Rat
6893681Bw109Body weight QTL 1092.30.004body mass (VT:0001259)body weight (CMO:0000012)12123297788Rat
1581516Cm56Cardiac mass QTL 564.20.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)12129333307Rat
1598855Bp294Blood pressure QTL 2943.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)12134851688Rat
7411660Foco28Food consumption QTL 2810.90.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12142110980Rat
9590086Insglur6Insulin/glucose ratio QTL 618.970.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)12142110980Rat
8694179Bw150Body weight QTL 1502.90.001body mass (VT:0001259)body weight gain (CMO:0000420)12142110980Rat
7411586Foco5Food consumption QTL 55.40.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12142110980Rat
7411595Foco9Food consumption QTL 940.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12142110980Rat
7411545Bw128Body weight QTL 1285.20.001body mass (VT:0001259)body weight gain (CMO:0000420)12142110980Rat
9590147Scort7Serum corticosterone level QTL 713.610.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)12142110980Rat
2303575Insul14Insulin level QTL 144blood insulin amount (VT:0001560)blood insulin level (CMO:0000349)12142450532Rat
737979Pia22Pristane induced arthritis QTL 2253.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)12144465750Rat
634351Apr5Acute phase response QTL 56.7blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)12144503507Rat
2302042Pia38Pristane induced arthritis QTL 383.50.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)12144503507Rat
7243862Mcs30Mammary carcinoma susceptibility QTL 308.62mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)127977298525593Rat
634350Apr4Acute phase response QTL 46orosomucoid 1 amount (VT:0010541)plasma orosomucoid 1 level (CMO:0001467)12117200546172005Rat


Related Rat Strains
The following Strains have been annotated to Insr

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:854
Count of miRNA genes:238
Interacting mature miRNAs:280
Transcripts:ENSRNOT00000041155, ENSRNOT00000067448
Prediction methods:Microtar, Miranda
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 41 51 39 12 39 8 8 74 35 33 11 8
Low 1 2 6 2 7 2 3 8
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_017071 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039089096 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039089097 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039089098 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AF005776 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF005777 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH004882 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH004883 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH007826 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ006071 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY566293 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC159409 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474084 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000223 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KF112847 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KF112848 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M29014 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U80633 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000041155   ⟹   ENSRNOP00000049655
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl121,197,100 - 1,330,883 (-)Ensembl
Rnor_6.0 Ensembl121,680,957 - 1,816,414 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000067448   ⟹   ENSRNOP00000060141
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl121,197,100 - 1,330,883 (-)Ensembl
Rnor_6.0 Ensembl121,682,527 - 1,816,414 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000113217   ⟹   ENSRNOP00000079583
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl121,197,100 - 1,330,883 (-)Ensembl
RefSeq Acc Id: NM_017071   ⟹   NP_058767
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2121,197,100 - 1,330,883 (-)NCBI
Rnor_6.0121,682,527 - 1,816,414 (-)NCBI
Rnor_5.0123,848,670 - 3,989,302 (-)NCBI
RGSC_v3.4122,934,967 - 3,087,691 (+)RGD
Celera123,053,590 - 3,185,991 (-)RGD
Sequence:
RefSeq Acc Id: XM_039089096   ⟹   XP_038945024
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2121,193,193 - 1,330,976 (-)NCBI
RefSeq Acc Id: XM_039089097   ⟹   XP_038945025
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2121,193,193 - 1,330,974 (-)NCBI
RefSeq Acc Id: XM_039089098   ⟹   XP_038945026
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2121,193,193 - 1,325,665 (-)NCBI
Protein Sequences
Protein RefSeqs NP_058767 (Get FASTA)   NCBI Sequence Viewer  
  XP_038945024 (Get FASTA)   NCBI Sequence Viewer  
  XP_038945025 (Get FASTA)   NCBI Sequence Viewer  
  XP_038945026 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA41441 (Get FASTA)   NCBI Sequence Viewer  
  AAB38746 (Get FASTA)   NCBI Sequence Viewer  
  AAB38967 (Get FASTA)   NCBI Sequence Viewer  
  AAB38968 (Get FASTA)   NCBI Sequence Viewer  
  AAB61414 (Get FASTA)   NCBI Sequence Viewer  
  AAB61415 (Get FASTA)   NCBI Sequence Viewer  
  AAD40886 (Get FASTA)   NCBI Sequence Viewer  
  AAD40887 (Get FASTA)   NCBI Sequence Viewer  
  AAD40888 (Get FASTA)   NCBI Sequence Viewer  
  AAD40889 (Get FASTA)   NCBI Sequence Viewer  
  AAD40890 (Get FASTA)   NCBI Sequence Viewer  
  AAD40891 (Get FASTA)   NCBI Sequence Viewer  
  AAD40892 (Get FASTA)   NCBI Sequence Viewer  
  AAD40893 (Get FASTA)   NCBI Sequence Viewer  
  AAD40894 (Get FASTA)   NCBI Sequence Viewer  
  AAD40895 (Get FASTA)   NCBI Sequence Viewer  
  AAD40896 (Get FASTA)   NCBI Sequence Viewer  
  AAD40897 (Get FASTA)   NCBI Sequence Viewer  
  AAT00542 (Get FASTA)   NCBI Sequence Viewer  
  AGV29469 (Get FASTA)   NCBI Sequence Viewer  
  AGV29470 (Get FASTA)   NCBI Sequence Viewer  
  EDL74923 (Get FASTA)   NCBI Sequence Viewer  
  EDL74924 (Get FASTA)   NCBI Sequence Viewer  
  EDL74925 (Get FASTA)   NCBI Sequence Viewer  
  P15127 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_058767   ⟸   NM_017071
- Peptide Label: preproprotein
- UniProtKB: T2CB11 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000060141   ⟸   ENSRNOT00000067448
RefSeq Acc Id: ENSRNOP00000049655   ⟸   ENSRNOT00000041155
RefSeq Acc Id: XP_038945024   ⟸   XM_039089096
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038945025   ⟸   XM_039089097
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038945026   ⟸   XM_039089098
- Peptide Label: isoform X3
RefSeq Acc Id: ENSRNOP00000079583   ⟸   ENSRNOT00000113217
Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698363
Promoter ID:EPDNEW_R8888
Type:initiation region
Name:Insr_1
Description:insulin receptor
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0121,816,502 - 1,816,562EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN-Lx/CubMcwi (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BUF/N (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
Buf/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
DA/OlaHsd (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
F344/Stm (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FXLE16/Stm (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GH/OmrMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/FarMcwi (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/Ox (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
HXB10/IpcvMcwi (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEXF10A/StmMcwi (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrcAek (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrcAek (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrcAek (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
M520/NRrrcMcwi (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MHS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MWF/Hsd (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SBH/Ygl (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/OlalpcvMcwi (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/Gcrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/RijCrl (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/Gcrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin