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Gene: Cux2 (cut-like homeobox 2) Rattus norvegicus
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Symbol: Cux2
Name: cut-like homeobox 2
Description: Predicted to have DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II proximal promoter sequence-specific DNA binding activity. Predicted to be involved in several processes, including positive regulation of nervous system development; regulation of gene expression; and short-term memory. Predicted to localize to the Golgi membrane and nucleus. Human ortholog(s) of this gene implicated in early infantile epileptic encephalopathy. Orthologous to human CUX2 (cut like homeobox 2); INTERACTS WITH 11-CYCLOPROPYL-5,11-DIHYDRO-4-METHYL-6H-DIPYRIDO[3,2-B:2',3'-E][1,4]DIAZEPIN-6-ONE; 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: cut-like 2; cut-like 2 (Drosophila); Cutl2; homeobox protein cut-like 2; LOC288665
Orthologs:
Homo sapiens (human) : CUX2 (cut like homeobox 2)  HGNC  Alliance
Mus musculus (house mouse) : Cux2 (cut-like homeobox 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cux2 (cut like homeobox 2)
Pan paniscus (bonobo/pygmy chimpanzee) : CUX2 (cut like homeobox 2)
Canis lupus familiaris (dog) : CUX2 (cut like homeobox 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cux2 (cut like homeobox 2)
Sus scrofa (pig) : CUX2 (cut like homeobox 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01240,016,774 - 40,221,067 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01241,893,143 - 42,092,024 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41235,850,093 - 35,910,414 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11235,727,879 - 35,773,518 (+)NCBI
Celera1236,188,363 - 36,371,360 (+)NCBICelera
Cytogenetic Map12q16NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Cux2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1305967
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.