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Gene: Cux2 (cut-like homeobox 2) Rattus norvegicus
Symbol: Cux2
Name: cut-like homeobox 2
RGD ID: 1305967
Description: Predicted to have DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in several processes, including regulation of gene expression; regulation of synapse organization; and short-term memory. Predicted to localize to nucleus. Human ortholog(s) of this gene implicated in early infantile epileptic encephalopathy. Orthologous to human CUX2 (cut like homeobox 2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; bromobenzene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: cut-like 2; cut-like 2 (Drosophila); Cutl2; homeobox protein cut-like 2; LOC288665
Homo sapiens (human) : CUX2 (cut like homeobox 2)  HGNC  Alliance
Mus musculus (house mouse) : Cux2 (cut-like homeobox 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cux2 (cut like homeobox 2)
Pan paniscus (bonobo/pygmy chimpanzee) : CUX2 (cut like homeobox 2)
Canis lupus familiaris (dog) : CUX2 (cut like homeobox 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cux2 (cut like homeobox 2)
Sus scrofa (pig) : CUX2 (cut like homeobox 2)
Chlorocebus sabaeus (African green monkey) : CUX2 (cut like homeobox 2)
Heterocephalus glaber (naked mole-rat) : Cux2 (cut like homeobox 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01240,016,774 - 40,221,067 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1240,018,937 - 40,219,291 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01241,893,143 - 42,092,024 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41235,850,093 - 35,910,414 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11235,727,879 - 35,773,518 (+)NCBI
Celera1236,188,363 - 36,371,360 (+)NCBICelera
Cytogenetic Map12q16NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Cux2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1305967
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.