Cux2 (cut like homeobox 2) - Rat Genome Database

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Gene: Cux2 (cut like homeobox 2) Heterocephalus glaber
Analyze
Symbol: Cux2
Name: cut like homeobox 2
RGD ID: 18900369
Description: ENCODES a protein that exhibits DNA-binding transcription repressor activity, RNA polymerase II-specific (ortholog); RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); sequence-specific DNA binding (ortholog); INVOLVED IN cognition (ortholog); negative regulation of DNA-templated transcription (ortholog); negative regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); developmental and epileptic encephalopathy 67 (ortholog); epilepsy with generalized tonic-clonic seizures (ortholog); FOUND IN intracellular membrane-bounded organelle (inferred); nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: homeobox protein cut-like 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474720,784,323 - 21,021,090 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
Cux2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474720,784,323 - 21,021,090 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
CUX2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3812111,034,165 - 111,350,554 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl12111,034,165 - 111,350,554 (+)EnsemblGRCh38hg38GRCh38
GRCh3712111,471,969 - 111,788,358 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3612109,956,212 - 110,272,739 (+)NCBINCBI36Build 36hg18NCBI36
Build 3412109,934,548 - 110,251,076NCBI
Celera12111,098,413 - 111,414,529 (+)NCBICelera
Cytogenetic Map12q24.11-q24.12NCBI
HuRef12108,667,813 - 108,803,094 (+)NCBIHuRef
CHM1_112111,439,881 - 111,756,318 (+)NCBICHM1_1
T2T-CHM13v2.012111,013,350 - 111,331,050 (+)NCBIT2T-CHM13v2.0
Cux2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395121,996,025 - 122,188,522 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5121,994,429 - 122,188,165 (-)EnsemblGRCm39 Ensembl
GRCm385121,857,962 - 122,050,415 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5121,856,366 - 122,050,102 (-)EnsemblGRCm38mm10GRCm38
MGSCv375122,310,225 - 122,497,834 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365122,120,833 - 122,308,442 (-)NCBIMGSCv36mm8
Celera5118,950,598 - 119,138,874 (-)NCBICelera
Cytogenetic Map5FNCBI
cM Map562.02NCBI
Cux2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81240,168,402 - 40,368,303 (+)NCBIGRCr8
mRatBN7.21234,507,723 - 34,707,581 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1234,520,959 - 34,705,806 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1235,693,412 - 35,878,823 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01236,304,624 - 36,490,037 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01235,357,113 - 35,542,505 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01240,016,774 - 40,221,067 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1240,018,937 - 40,219,291 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01241,893,143 - 42,092,024 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41235,850,093 - 35,910,414 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11235,727,879 - 35,773,518 (+)NCBI
Celera1236,188,363 - 36,371,360 (+)NCBICelera
Cytogenetic Map12q16NCBI
Cux2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554827,955,039 - 8,043,533 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554827,783,483 - 8,045,808 (+)NCBIChiLan1.0ChiLan1.0
CUX2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v210119,094,013 - 119,417,278 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan112119,090,421 - 119,465,960 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v012108,600,286 - 108,975,588 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.112112,143,682 - 112,313,451 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl12112,175,555 - 112,311,221 (+)Ensemblpanpan1.1panPan2
CUX2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1268,711,816 - 8,997,263 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl268,730,435 - 8,993,205 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha268,874,945 - 9,160,037 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0268,971,508 - 9,256,848 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl268,990,189 - 9,255,070 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1268,928,111 - 9,212,941 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0268,990,069 - 9,275,112 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0268,943,481 - 9,228,574 (+)NCBIUU_Cfam_GSD_1.0
Cux2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118155,419,639 - 155,516,332 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049365583,970,114 - 4,060,326 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CUX2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1432,311,188 - 32,587,203 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11432,311,781 - 32,587,194 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21434,262,426 - 34,582,740 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CUX2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.111106,462,877 - 106,602,847 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666037138,495,924 - 138,814,132 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


RefSeq Acc Id: XM_004843801   ⟹   XP_004843858
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474720,784,323 - 20,975,527 (-)NCBI
RefSeq Acc Id: XM_004843802   ⟹   XP_004843859
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474720,784,323 - 21,021,090 (-)NCBI
RefSeq Acc Id: XM_021257476   ⟹   XP_021113135
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474720,784,323 - 20,975,529 (-)NCBI
RefSeq Acc Id: XM_021257477   ⟹   XP_021113136
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474720,784,323 - 21,021,090 (-)NCBI
RefSeq Acc Id: XM_021257478   ⟹   XP_021113137
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474720,784,323 - 20,975,528 (-)NCBI
RefSeq Acc Id: XM_021257479   ⟹   XP_021113138
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474720,784,323 - 21,021,090 (-)NCBI
RefSeq Acc Id: XM_021257481   ⟹   XP_021113140
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474720,784,323 - 20,975,529 (-)NCBI
RefSeq Acc Id: XM_021257482   ⟹   XP_021113141
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474720,784,323 - 20,975,528 (-)NCBI
RefSeq Acc Id: XM_021257483   ⟹   XP_021113142
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474720,784,323 - 20,963,651 (-)NCBI
RefSeq Acc Id: XM_021257484   ⟹   XP_021113143
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474720,784,323 - 20,975,531 (-)NCBI
RefSeq Acc Id: XM_021257485   ⟹   XP_021113144
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474720,784,323 - 20,816,834 (-)NCBI
RefSeq Acc Id: XP_004843859   ⟸   XM_004843802
- Peptide Label: isoform X7
- UniProtKB: G5AKU2 (UniProtKB/TrEMBL),   A0AAX6P4T5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021113138   ⟸   XM_021257479
- Peptide Label: isoform X4
- UniProtKB: G5AKU2 (UniProtKB/TrEMBL),   A0AAX6SXV0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021113136   ⟸   XM_021257477
- Peptide Label: isoform X2
- UniProtKB: G5AKU2 (UniProtKB/TrEMBL),   A0AAX6SXR8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021113143   ⟸   XM_021257484
- Peptide Label: isoform X10
- UniProtKB: G5AKU2 (UniProtKB/TrEMBL),   A0AAX6SZF5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021113140   ⟸   XM_021257481
- Peptide Label: isoform X5
- UniProtKB: G5AKU2 (UniProtKB/TrEMBL),   A0AAX6SZH2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021113135   ⟸   XM_021257476
- Peptide Label: isoform X1
- UniProtKB: G5AKU2 (UniProtKB/TrEMBL),   A0AAX6SXD9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021113141   ⟸   XM_021257482
- Peptide Label: isoform X8
- UniProtKB: G5AKU2 (UniProtKB/TrEMBL),   A0AAX6SUS0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021113137   ⟸   XM_021257478
- Peptide Label: isoform X3
- UniProtKB: G5AKU2 (UniProtKB/TrEMBL),   A0AAX6SZ80 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004843858   ⟸   XM_004843801
- Peptide Label: isoform X6
- UniProtKB: G5AKU2 (UniProtKB/TrEMBL),   A0AAX6P5D5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021113142   ⟸   XM_021257483
- Peptide Label: isoform X9
- UniProtKB: G5AKU2 (UniProtKB/TrEMBL),   A0AAX6STS4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021113144   ⟸   XM_021257485
- Peptide Label: isoform X11
- UniProtKB: G5AKU2 (UniProtKB/TrEMBL),   A0AAX6SXG3 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Gene3D-CATH Homeodomain-like UniProtKB/TrEMBL
  lambda repressor-like DNA-binding domains UniProtKB/TrEMBL
InterPro CUT_dom UniProtKB/TrEMBL
  Homeobox-like_sf UniProtKB/TrEMBL
  Homeobox_CS UniProtKB/TrEMBL
  Homeobox_dom UniProtKB/TrEMBL
  Lambda_DNA-bd_dom_sf UniProtKB/TrEMBL
NCBI Gene Cux2 ENTREZGENE
PANTHER CCAAT DISPLACEMENT PROTEIN-RELATED UniProtKB/TrEMBL
  HOMEOBOX PROTEIN CUT-LIKE 2 UniProtKB/TrEMBL
Pfam CUT UniProtKB/TrEMBL
  Homeodomain UniProtKB/TrEMBL
PROSITE CUT UniProtKB/TrEMBL
  HOMEOBOX_1 UniProtKB/TrEMBL
  HOMEOBOX_2 UniProtKB/TrEMBL
SMART CUT UniProtKB/TrEMBL
  HOX UniProtKB/TrEMBL
Superfamily-SCOP Homeodomain-like UniProtKB/TrEMBL
  lambda repressor-like DNA-binding domains UniProtKB/TrEMBL
UniProt A0AAX6P4T5 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6P5D5 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6STS4 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6SUS0 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6SXD9 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6SXG3 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6SXR8 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6SXV0 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6SZ80 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6SZF5 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6SZH2 ENTREZGENE, UniProtKB/TrEMBL
  G5AKU2 ENTREZGENE, UniProtKB/TrEMBL