Cyp3a2 (cytochrome P450, family 3, subfamily a, polypeptide 2) - Rat Genome Database

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Gene: Cyp3a2 (cytochrome P450, family 3, subfamily a, polypeptide 2) Rattus norvegicus
Symbol: Cyp3a2 (Ensembl: Cyp3a23-3a1)
Name: cytochrome P450, family 3, subfamily a, polypeptide 2 (Ensembl:cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1)
RGD ID: 708379
Description: Enables demethylase activity and testosterone 6-beta-hydroxylase activity. Involved in oxidative demethylation and xenobiotic metabolic process. Predicted to be located in cytoplasm. Used to study anxiety disorder. Biomarker of cholestasis and end stage renal disease. Human ortholog(s) of this gene implicated in B-lymphoblastic leukemia/lymphoma; acute lymphoblastic leukemia; chronic myeloid leukemia; and essential hypertension. Orthologous to human CYP3A5 (cytochrome P450 family 3 subfamily A member 5); PARTICIPATES IN tamoxifen pharmacokinetics pathway; artemether pharmacokinetics pathway; axitinib pharmacokinetics pathway; INTERACTS WITH (R,R,R)-alpha-tocopherol; (S)-nicotine; 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Cyp3a11; CYPIIIA2; cytochrome P450 3A2; cytochrome P450, family 3, subfamily a, polypeptide 11; cytochrome P450-PCN2; cytochrome P450/6-beta-A; MGC108545; P450-PCN2; P450/6-beta-A; testosterone 6-beta-hydroxylase
RGD Orthologs
Green Monkey
Alliance Genes
More Info more info ...
Allele / Splice: Cyp3a2em1Myliu  
Genetic Models: SD-Cyp3a23/3a1em1Myliu,Cyp3a2em1Myliu
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
mRatBN7.2129,207,986 - 9,230,038 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl129,015,383 - 9,285,008 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1210,009,578 - 10,031,654 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.01210,632,755 - 10,654,831 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0129,656,186 - 9,678,268 (-)NCBIRnor_WKY
Rnor_6.01211,641,500 - 11,677,818 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1211,655,402 - 11,733,136 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01213,719,927 - 13,740,743 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4129,517,016 - 9,541,000 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1129,546,940 - 9,570,928 (-)NCBI
Celera1210,992,673 - 11,037,068 (-)NCBICelera
Cytogenetic Map12p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)