Cyp3a2 (cytochrome P450, family 3, subfamily a, polypeptide 2) - Rat Genome Database

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Gene: Cyp3a2 (cytochrome P450, family 3, subfamily a, polypeptide 2) Rattus norvegicus
Symbol: Cyp3a2
Name: cytochrome P450, family 3, subfamily a, polypeptide 2
RGD ID: 708379
Description: Enables demethylase activity and testosterone 6-beta-hydroxylase activity. Involved in oxidative demethylation and xenobiotic metabolic process. Predicted to be located in cytoplasm. Used to study anxiety disorder. Biomarker of cholestasis and end stage renal disease. Human ortholog(s) of this gene implicated in B-lymphoblastic leukemia/lymphoma; acute lymphoblastic leukemia; chronic myeloid leukemia; and essential hypertension. Orthologous to human CYP3A5 (cytochrome P450 family 3 subfamily A member 5); PARTICIPATES IN tamoxifen pharmacokinetics pathway; artemether pharmacokinetics pathway; axitinib pharmacokinetics pathway; INTERACTS WITH (R,R,R)-alpha-tocopherol; (S)-nicotine; 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Cyp3a11; CYPIIIA2; cytochrome P450 3A2; cytochrome P450, family 3, subfamily a, polypeptide 11; cytochrome P450-PCN2; cytochrome P450/6-beta-A; MGC108545; P450-PCN2; P450/6-beta-A; testosterone 6-beta-hydroxylase
RGD Orthologs
Green Monkey
Alliance Genes
More Info more info ...
Allele / Splice: Cyp3a2em1Myliu  
Genetic Models: SD-Cyp3a23/3a1em1Myliu,Cyp3a2em1Myliu
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
GRCr81214,321,771 - 14,343,886 (-)NCBIGRCr8
mRatBN7.2129,207,978 - 9,230,064 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl129,015,383 - 9,285,008 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1210,009,578 - 10,031,654 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01210,632,755 - 10,654,831 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0129,656,186 - 9,678,268 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01211,641,500 - 11,677,818 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1211,655,402 - 11,733,136 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01213,719,927 - 13,740,743 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4129,517,016 - 9,541,000 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1129,546,940 - 9,570,928 (-)NCBI
Celera1210,992,673 - 11,037,068 (-)NCBICelera
Cytogenetic Map12p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)