GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Cyp3a2 | decreases activity | ISO | CYP3A4 (Homo sapiens) | 6480464 | CTD | fenvalerate results in decreased activity of CYP3A4 protein | PMID:22634058 | Cyp3a2 | increases activity | ISO | CYP3A4 (Homo sapiens) | 6480464 | CTD | fenvalerate results in increased activity of CYP3A4 protein | PMID:22310298 | Cyp3a2 | increases expression | ISO | CYP3A4 (Homo sapiens) | 6480464 | CTD | fenvalerate results in increased expression of CYP3A4 mRNA; fenvalerate results in increased expression of CYP3A4 protein | PMID:15548381 PMID:19249324 PMID:20599767 PMID:22310298 | Cyp3a2 | multiple interactions | ISO | CYP3A4 (Homo sapiens) | 6480464 | CTD | Dexamethasone promotes the reaction [fenvalerate results in increased expression of CYP3A4 mRNA]; fenvalerate promotes the reaction [Dexamethasone results in increased expression of CYP3A4 mRNA] | PMID:20599767 | | ||||||||||||||||||||||
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