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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 708379
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyp3a2
Name: cytochrome P450, family 3, subfamily a, polypeptide 2
Acc ID: CHEBI:136492
Term: N-(2,6-diethylphenyl)-2-chloroacetamide
Definition: An aromatic amide obtained by formal condensation of the carboxy group of chloroacetic acid with the amnio group of 2,6-diethylaniline.
Chemical ID: MESH:C093872
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp3a2increases abundanceISORGD:13529626480464CTDCYP3A4 protein results in increased abundance of 2-chloro-N-(2,6-diethylphenyl)acetamidePMID:18273908
Cyp3a2increases chemical synthesisISORGD:13529626480464CTDCYP3A4 protein results in increased chemical synthesis of 2-chloro-N-(2,6-diethylphenyl)acetamidePMID:10475613
Cyp3a2multiple interactionsISORGD:13529626480464CTD[CYP3A4 protein results in increased metabolism of alachlor] which results in increased abundance of 2-chloro-N-(2,6-diethylphenyl)acetamidePMID:18273908
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