GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Cyp3a2 | affects binding | ISO | CYP3A4 (Homo sapiens) | 6480464 | CTD | CYP3A4 protein binds to Ritonavir analog | PMID:27966929 | Cyp3a2 | affects metabolic processing | ISO | CYP3A4 (Homo sapiens) | 6480464 | CTD | CYP3A4 protein affects the metabolism of Ritonavir | PMID:15286053 | Cyp3a2 | decreases activity | ISO | CYP3A4 (Homo sapiens) | 6480464 | CTD | Ritonavir results in decreased activity of CYP3A4 protein | PMID:15523003 PMID:15860655 PMID:26626330 | Cyp3a2 | increases expression | ISO | CYP3A4 (Homo sapiens) | 6480464 | CTD | Ritonavir results in increased expression of CYP3A4 mRNA | PMID:16837568 | |
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