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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 708379
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyp3a2
Name: cytochrome P450, family 3, subfamily a, polypeptide 2
Acc ID: CHEBI:177719
Term: Avasimibe
Definition: null
Chemical ID: MESH:C423185
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp3a2increases expressionISOCYP3A4 (Homo sapiens)6480464CTDavasimibe results in increased expression of CYP3A4 mRNAPMID:16837568
Cyp3a2multiple interactionsISOCYP3A4 (Homo sapiens)6480464CTDavasimibe results in increased activity of and results in increased expression of CYP3A4 proteinPMID:19202563
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