GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Cyp3a2 | increases activity | ISO | CYP3A4 (Homo sapiens) | 6480464 | CTD | 2-acetyltributylcitrate results in increased activity of CYP3A4 protein | PMID:21742782 | Cyp3a2 | increases expression | ISO | CYP3A4 (Homo sapiens) | 6480464 | CTD | 2-acetyltributylcitrate results in increased expression of CYP3A4 mRNA | PMID:21742782 | Cyp3a2 | multiple interactions | ISO | CYP3A4 (Homo sapiens) | 6480464 | CTD | 2-acetyltributylcitrate promotes the reaction [Calcitriol results in increased expression of CYP3A4 mRNA]; 2-acetyltributylcitrate promotes the reaction [NR1I2 protein results in increased expression of CYP3A4 mRNA]; Calcitriol promotes the reaction [2-acetyltributylcitrate results in increased activity of CYP3A4 protein]; Calcitriol promotes the reaction [2-acetyltributylcitrate results in increased expression of CYP3A4 mRNA]; NR1I2 protein affects the reaction [2-acetyltributylcitrate results in increased expression of CYP3A4 mRNA] | PMID:21742782 | | ||||||||||||||||||||||
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