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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 708379
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyp3a2
Name: cytochrome P450, family 3, subfamily a, polypeptide 2
Acc ID: CHEBI:138308
Term: kahweol
Definition: A diterpenoid with formula C20H26O3, isolated from the beans of Coffea arabica. It exhibits antioxidant, anti-inflammatory, anti-angiogenesis and anti-proliferative properties.
Chemical ID: MESH:C053401
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp3a2multiple interactionsEXP 6480464CTD[cafestol co-treated with kahweol] results in decreased expression of CYP3A2; [cafestol co-treated with kahweol] results in decreased expression of CYP3A2 proteinPMID:11346484 PMID:9744531
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