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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 708379
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyp3a2
Name: cytochrome P450, family 3, subfamily a, polypeptide 2
Acc ID: CHEBI:81855
Term: Bromadiolone
Definition: A diarylheptanoid that has formula C30H23BrO4.
Chemical ID: MESH:C021636
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp3a2decreases response to substanceEXP 6480464CTDCYP3A2 protein results in decreased susceptibility to bromadiolonePMID:18080289
Cyp3a2increases expressionEXP 6480464CTDbromadiolone results in increased expression of CYP3A2 mRNAPMID:18080289
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