Sfswap (splicing factor SWAP) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Sfswap (splicing factor SWAP) Rattus norvegicus
Analyze
Symbol: Sfswap
Name: splicing factor SWAP
RGD ID: 1305004
Description: Predicted to enable RNA binding activity. Involved in negative regulation of mRNA splicing, via spliceosome. Predicted to be located in nucleus. Orthologous to human SFSWAP (splicing factor SWAP); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; decabromodiphenyl ether.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC304431; MGC125102; serine/arginine-rich splicing factor 8; Sfrs8; splicing factor SWAP homolog; splicing factor, arginine/serine-rich 8; splicing factor, arginine/serine-rich 8 (suppressor-of-white-apricot homolog, Drosophila); splicing factor, suppressor of white-apricot family; splicing factor, suppressor of white-apricot homolog; splicing factor, suppressor of white-apricot homolog (Drosophila); Srsf8; suppressor of white apricot protein homolog
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81232,745,704 - 32,816,032 (-)NCBIGRCr8
mRatBN7.21227,109,607 - 27,179,941 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1227,109,611 - 27,179,884 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1228,246,004 - 28,316,319 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01228,856,567 - 28,926,883 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01227,918,044 - 27,988,360 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01230,740,563 - 30,811,015 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1230,740,520 - 30,811,054 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01232,675,284 - 32,745,308 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41228,179,091 - 28,249,425 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11228,039,375 - 28,112,849 (-)NCBI
Celera1228,813,478 - 28,883,636 (-)NCBICelera
Cytogenetic Map12q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleus  (IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. GOA pipeline RGD automated data pipeline
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. Tau exon 10, whose missplicing causes frontotemporal dementia, is regulated by an intricate interplay of cis elements and trans factors. Wang J, etal., J Neurochem. 2004 Mar;88(5):1078-90.
Additional References at PubMed
PMID:8940107   PMID:12477932  


Genomics

Comparative Map Data
Sfswap
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81232,745,704 - 32,816,032 (-)NCBIGRCr8
mRatBN7.21227,109,607 - 27,179,941 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1227,109,611 - 27,179,884 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1228,246,004 - 28,316,319 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01228,856,567 - 28,926,883 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01227,918,044 - 27,988,360 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01230,740,563 - 30,811,015 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1230,740,520 - 30,811,054 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01232,675,284 - 32,745,308 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41228,179,091 - 28,249,425 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11228,039,375 - 28,112,849 (-)NCBI
Celera1228,813,478 - 28,883,636 (-)NCBICelera
Cytogenetic Map12q13NCBI
SFSWAP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3812131,711,090 - 131,799,738 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl12131,711,081 - 131,799,738 (+)EnsemblGRCh38hg38GRCh38
GRCh3712132,195,635 - 132,284,283 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3612130,761,588 - 130,850,235 (+)NCBINCBI36Build 36hg18NCBI36
Build 3412130,861,864 - 130,950,512NCBI
Celera12131,812,182 - 131,900,934 (+)NCBICelera
Cytogenetic Map12q24.33NCBI
HuRef12129,080,987 - 129,170,070 (+)NCBIHuRef
CHM1_112132,010,269 - 132,105,145 (+)NCBICHM1_1
T2T-CHM13v2.012131,753,414 - 131,843,835 (+)NCBIT2T-CHM13v2.0
Sfswap
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395129,578,286 - 129,648,448 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5129,578,285 - 129,648,448 (+)EnsemblGRCm39 Ensembl
GRCm385129,501,231 - 129,571,384 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5129,501,221 - 129,571,384 (+)EnsemblGRCm38mm10GRCm38
MGSCv375130,007,106 - 130,077,259 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365129,815,939 - 129,886,092 (+)NCBIMGSCv36mm8
Celera5126,543,991 - 126,614,293 (+)NCBICelera
Cytogenetic Map5G1.3NCBI
cM Map568.13NCBI
Sfswap
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955482808,632 - 871,402 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955482808,684 - 871,377 (-)NCBIChiLan1.0ChiLan1.0
SFSWAP
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v210139,799,194 - 139,887,413 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan112139,795,885 - 139,883,919 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v012129,362,704 - 129,450,678 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.112133,793,149 - 133,881,150 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl12133,793,300 - 133,880,910 (+)Ensemblpanpan1.1panPan2
SFSWAP
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1261,035,059 - 1,104,730 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl261,035,074 - 1,104,694 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha261,083,285 - 1,153,081 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0261,101,263 - 1,171,503 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl261,101,269 - 1,171,494 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1261,038,422 - 1,108,212 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0261,134,994 - 1,204,741 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0261,058,218 - 1,128,003 (-)NCBIUU_Cfam_GSD_1.0
Sfswap
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118122,600,083 - 122,666,141 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366602,054,978 - 2,121,279 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366602,055,180 - 2,121,008 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SFSWAP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1423,516,257 - 23,594,257 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11423,516,253 - 23,594,252 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21424,981,763 - 25,059,559 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SFSWAP
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.111127,086,690 - 127,177,327 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl11127,086,668 - 127,177,324 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037117,843,829 - 117,940,423 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sfswap
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474727,588,285 - 27,656,660 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474727,588,684 - 27,653,704 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Sfswap
203 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:258
Count of miRNA genes:165
Interacting mature miRNAs:190
Transcripts:ENSRNOT00000001235
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631560Apr1Acute phase response QTL 16.1orosomucoid 1 amount (VT:0010541)plasma orosomucoid 1 level (CMO:0001467)121914436246669029Rat
8552964Pigfal17Plasma insulin-like growth factor 1 level QTL 173.5blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449546669029Rat
61324Eae5Experimental allergic encephalomyelitis QTL 514nervous system integrity trait (VT:0010566)percentage of study population developing relapsing-remitting experimental autoimmune encephalomyelitis during a period of time (CMO:0001402)121961087046669029Rat
9590147Scort7Serum corticosterone level QTL 713.610.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)12142110980Rat
1549829Scl48Serum cholesterol level QTL 485blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)12960327746669029Rat
61331Eau2Experimental allergic uveoretinitis QTL 20.0005uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)12852542328064601Rat
737822Alc10Alcohol consumption QTL 102.2consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)121961087040218516Rat
2293684Bmd26Bone mineral density QTL 264.40.0002femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)121587265332974238Rat
70169Eae13Experimental allergic encephalomyelitis QTL 130.032nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)122413920236638073Rat
1302792Scl21Serum cholesterol level QTL 213.80.0011blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)12719673046669029Rat
1598855Bp294Blood pressure QTL 2943.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)12134851688Rat
1331761Bp218Blood pressure QTL 2182.973arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)121107382545055165Rat
8694179Bw150Body weight QTL 1502.90.001body mass (VT:0001259)body weight gain (CMO:0000420)12142110980Rat
1331763Wbc2White blood cell count QTL 23.162leukocyte quantity (VT:0000217)total white blood cell count (CMO:0000365)122423477731894213Rat
7411545Bw128Body weight QTL 1285.20.001body mass (VT:0001259)body weight gain (CMO:0000420)12142110980Rat
7411547Bw129Body weight QTL 1290.001body mass (VT:0001259)body weight gain (CMO:0000420)6556449546669029Rat
1300157Rf21Renal function QTL 214.4renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)12931821632103380Rat
737979Pia22Pristane induced arthritis QTL 2253.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)12144465750Rat
1298081Cia25Collagen induced arthritis QTL 254.7joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)121961088935682913Rat
2300186Bmd59Bone mineral density QTL 597.10.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)121047413746669029Rat
7411660Foco28Food consumption QTL 2810.90.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12142110980Rat
1331755Bp219Blood pressure QTL 2193.041arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)121107382528064557Rat
70213Niddm27Non-insulin dependent diabetes mellitus QTL 273.72blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)121983578938193007Rat
7411641Foco19Food consumption QTL 1927.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12556449546669029Rat
7411643Foco20Food consumption QTL 200.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)122032881946669029Rat
5684888Pia42Pristane induced arthritis QTL 42joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)121961087042828880Rat
1549912Bp268Blood pressure QTL 268arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)101318273646669029Rat
2302060Pia37Pristane induced arthritis QTL 376.10.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)121319815746669029Rat
1641928Alcrsp5Alcohol response QTL 5response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)121281238546669029Rat
8552912Pigfal6Plasma insulin-like growth factor 1 level QTL 65blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449846669029Rat
10059594Kidm46Kidney mass QTL 463.790.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)12610757946669029Rat
1581516Cm56Cardiac mass QTL 564.20.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)12129333307Rat
9590086Insglur6Insulin/glucose ratio QTL 618.970.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)12142110980Rat
8552918Pigfal7Plasma insulin-like growth factor 1 level QTL 7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449546669029Rat
1549902Bp269Blood pressure QTL 269arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)121318273646669029Rat
61404Bw120Body weight QTL 1205.1body mass (VT:0001259)body mass index (BMI) (CMO:0000105)121235161946669029Rat
2293699Bss49Bone structure and strength QTL 495.610.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra trabecular cross-sectional area (CMO:0001692)121047413746669029Rat
634351Apr5Acute phase response QTL 56.7blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)12144503507Rat
634350Apr4Acute phase response QTL 46orosomucoid 1 amount (VT:0010541)plasma orosomucoid 1 level (CMO:0001467)12117200546172005Rat
61416Pia4Pristane induced arthritis QTL 48.4joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)121363552330827399Rat
61421Cia12Collagen induced arthritis QTL 124.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)121363552335682913Rat
2303569Gluco44Glucose level QTL 442blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)121281238546669029Rat
7411586Foco5Food consumption QTL 55.40.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12142110980Rat
2303575Insul14Insulin level QTL 144blood insulin amount (VT:0001560)blood insulin level (CMO:0000349)12142450532Rat
7411588Foco6Food consumption QTL 60.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12556449546669029Rat
2302042Pia38Pristane induced arthritis QTL 383.50.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)12144503507Rat
7411595Foco9Food consumption QTL 940.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12142110980Rat
7411597Foco10Food consumption QTL 100.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12556449546669029Rat
2293086Iddm30Insulin dependent diabetes mellitus QTL 303.82blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)12844949028302290Rat
631543Bp83Blood pressure QTL 835.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)121555082638478808Rat

Markers in Region
D16S505  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21227,172,029 - 27,172,147 (+)MAPPERmRatBN7.2
mRatBN7.23129,052,956 - 129,053,750 (+)MAPPERmRatBN7.2
Rnor_6.03135,738,830 - 135,739,623NCBIRnor6.0
Rnor_6.01230,803,111 - 30,803,228NCBIRnor6.0
Rnor_5.01232,737,419 - 32,737,536UniSTSRnor5.0
Rnor_5.03142,185,974 - 142,186,767UniSTSRnor5.0
RGSC_v3.43129,992,101 - 129,992,894UniSTSRGSC3.4
RGSC_v3.41228,241,572 - 28,241,689UniSTSRGSC3.4
Celera1228,875,783 - 28,875,900UniSTS
Celera3127,675,514 - 127,676,307UniSTS
Cytogenetic Map3q41UniSTS
Cytogenetic Map12q13UniSTS
AW212079  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21227,109,739 - 27,109,833 (+)MAPPERmRatBN7.2
Rnor_6.01230,740,696 - 30,740,789NCBIRnor6.0
Rnor_5.01232,675,417 - 32,675,510UniSTSRnor5.0
RGSC_v3.41228,179,221 - 28,179,314UniSTSRGSC3.4
Celera1228,813,608 - 28,813,701UniSTS
Cytogenetic Map12q13UniSTS
BF405946  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21227,131,925 - 27,132,119 (+)MAPPERmRatBN7.2
Rnor_6.01230,762,880 - 30,763,073NCBIRnor6.0
Rnor_5.01232,697,601 - 32,697,794UniSTSRnor5.0
RGSC_v3.41228,201,405 - 28,201,598UniSTSRGSC3.4
Celera1228,835,792 - 28,835,985UniSTS
RH 3.4 Map12447.0UniSTS
Cytogenetic Map12q13UniSTS
RH135132  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21227,129,548 - 27,130,794 (+)MAPPERmRatBN7.2
Rnor_6.01230,760,503 - 30,761,748NCBIRnor6.0
Rnor_5.01232,695,224 - 32,696,469UniSTSRnor5.0
RGSC_v3.41228,199,028 - 28,200,273UniSTSRGSC3.4
Celera1228,833,415 - 28,834,660UniSTS
RH 3.4 Map12454.3UniSTS
Cytogenetic Map12q13UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001034924 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001400984 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006249269 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006249270 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006249271 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006249273 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008769196 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008769197 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039089425 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039089426 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039089427 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063271297 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063271298 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063271299 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BC091384 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC105868 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473973 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000012 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000001235   ⟹   ENSRNOP00000001235
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1230,740,566 - 30,810,964 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000077977   ⟹   ENSRNOP00000070951
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1227,109,611 - 27,179,884 (-)Ensembl
Rnor_6.0 Ensembl1230,740,520 - 30,811,054 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000093199
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1230,750,888 - 30,751,544 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000093237   ⟹   ENSRNOP00000076174
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1227,109,611 - 27,179,884 (-)Ensembl
Rnor_6.0 Ensembl1230,740,563 - 30,811,000 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000093278
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1230,740,566 - 30,762,467 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000093286
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1230,809,207 - 30,811,000 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000093391
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1230,807,853 - 30,808,550 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000093652
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1230,741,155 - 30,742,491 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000093734   ⟹   ENSRNOP00000076147
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1230,761,901 - 30,770,791 (-)Ensembl
RefSeq Acc Id: NM_001034924   ⟹   NP_001030096
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81232,745,707 - 32,815,976 (-)NCBI
mRatBN7.21227,109,610 - 27,179,884 (-)NCBI
Rnor_6.01230,740,566 - 30,810,964 (-)NCBI
Rnor_5.01232,675,284 - 32,745,308 (-)NCBI
RGSC_v3.41228,179,091 - 28,249,425 (-)RGD
Celera1228,813,478 - 28,883,636 (-)RGD
Sequence:
RefSeq Acc Id: NM_001400984   ⟹   NP_001387913
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81232,745,704 - 32,816,032 (-)NCBI
mRatBN7.21227,109,607 - 27,179,940 (-)NCBI
RefSeq Acc Id: XM_006249269   ⟹   XP_006249331
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81232,745,704 - 32,816,018 (-)NCBI
mRatBN7.21227,109,607 - 27,179,939 (-)NCBI
Rnor_6.01230,740,563 - 30,811,014 (-)NCBI
Rnor_5.01232,675,284 - 32,745,308 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006249270   ⟹   XP_006249332
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81232,745,704 - 32,816,018 (-)NCBI
mRatBN7.21227,109,607 - 27,179,939 (-)NCBI
Rnor_6.01230,740,563 - 30,811,014 (-)NCBI
Rnor_5.01232,675,284 - 32,745,308 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006249271   ⟹   XP_006249333
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81232,745,704 - 32,816,025 (-)NCBI
mRatBN7.21227,109,607 - 27,179,938 (-)NCBI
Rnor_6.01230,740,563 - 30,811,014 (-)NCBI
Rnor_5.01232,675,284 - 32,745,308 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006249273   ⟹   XP_006249335
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81232,745,704 - 32,816,018 (-)NCBI
mRatBN7.21227,109,607 - 27,179,938 (-)NCBI
Rnor_6.01230,740,563 - 30,811,014 (-)NCBI
Rnor_5.01232,675,284 - 32,745,308 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008769196   ⟹   XP_008767418
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81232,745,704 - 32,816,018 (-)NCBI
mRatBN7.21227,109,607 - 27,179,940 (-)NCBI
Rnor_6.01230,740,563 - 30,811,014 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008769197   ⟹   XP_008767419
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81232,745,704 - 32,816,018 (-)NCBI
mRatBN7.21227,109,607 - 27,179,941 (-)NCBI
Rnor_6.01230,740,563 - 30,811,015 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039089425   ⟹   XP_038945353
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81232,745,704 - 32,816,030 (-)NCBI
mRatBN7.21227,109,607 - 27,179,940 (-)NCBI
RefSeq Acc Id: XM_039089426   ⟹   XP_038945354
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81232,745,704 - 32,816,030 (-)NCBI
mRatBN7.21227,109,607 - 27,179,937 (-)NCBI
RefSeq Acc Id: XM_039089427   ⟹   XP_038945355
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81232,745,704 - 32,800,775 (-)NCBI
mRatBN7.21227,109,607 - 27,164,682 (-)NCBI
RefSeq Acc Id: XM_063271297   ⟹   XP_063127367
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81232,747,286 - 32,816,018 (-)NCBI
RefSeq Acc Id: XM_063271298   ⟹   XP_063127368
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81232,747,323 - 32,816,018 (-)NCBI
RefSeq Acc Id: XM_063271299   ⟹   XP_063127369
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81232,745,704 - 32,816,030 (-)NCBI
RefSeq Acc Id: NP_001030096   ⟸   NM_001034924
- Peptide Label: isoform 2
- UniProtKB: Q3KR71 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006249335   ⟸   XM_006249273
- Peptide Label: isoform X6
- UniProtKB: A0A1W2Q681 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006249332   ⟸   XM_006249270
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_006249331   ⟸   XM_006249269
- Peptide Label: isoform X2
- UniProtKB: A0A0G2JZ87 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006249333   ⟸   XM_006249271
- Peptide Label: isoform X5
- UniProtKB: Q5BJQ4 (UniProtKB/Swiss-Prot),   D3ZTQ1 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_008767419   ⟸   XM_008769197
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_008767418   ⟸   XM_008769196
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSRNOP00000070951   ⟸   ENSRNOT00000077977
Ensembl Acc Id: ENSRNOP00000076147   ⟸   ENSRNOT00000093734
Ensembl Acc Id: ENSRNOP00000076174   ⟸   ENSRNOT00000093237
Ensembl Acc Id: ENSRNOP00000001235   ⟸   ENSRNOT00000001235
RefSeq Acc Id: XP_038945353   ⟸   XM_039089425
- Peptide Label: isoform X7
RefSeq Acc Id: XP_038945354   ⟸   XM_039089426
- Peptide Label: isoform X9
- UniProtKB: A6J0R5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038945355   ⟸   XM_039089427
- Peptide Label: isoform X11
RefSeq Acc Id: NP_001387913   ⟸   NM_001400984
- Peptide Label: isoform 1
RefSeq Acc Id: XP_063127369   ⟸   XM_063271299
- Peptide Label: isoform X10
- UniProtKB: Q3KR71 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063127367   ⟸   XM_063271297
- Peptide Label: isoform X8
RefSeq Acc Id: XP_063127368   ⟸   XM_063271298
- Peptide Label: isoform X8
Protein Domains
SURP motif

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZTQ1-F1-model_v2 AlphaFold D3ZTQ1 1-945 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698592
Promoter ID:EPDNEW_R9117
Type:multiple initiation site
Name:Sfswap_1
Description:splicing factor SWAP
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01230,810,995 - 30,811,055EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305004 AgrOrtholog
BioCyc Gene G2FUF-19484 BioCyc
Ensembl Genes ENSRNOG00000000931 Ensembl, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOG00055000361 UniProtKB/Swiss-Prot
  ENSRNOG00060011465 UniProtKB/Swiss-Prot
  ENSRNOG00065001420 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000077977.2 UniProtKB/TrEMBL
  ENSRNOT00000093237 UniProtKB/TrEMBL
  ENSRNOT00000093237.2 UniProtKB/Swiss-Prot
  ENSRNOT00055000649 UniProtKB/Swiss-Prot
  ENSRNOT00060019419 UniProtKB/Swiss-Prot
  ENSRNOT00065001884 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.10.790 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7321112 IMAGE-MGC_LOAD
  IMAGE:7462407 IMAGE-MGC_LOAD
InterPro Surp UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SWAP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SWAP/Surp_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SWAP_N_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:109465 IMAGE-MGC_LOAD
  MGC:125102 IMAGE-MGC_LOAD
NCBI Gene 304431 ENTREZGENE
PANTHER PTHR13161 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SPLICING FACTOR, SUPPRESSOR OF WHITE-APRICOT HOMOLOG UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam DRY_EERY UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Surp UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Sfswap PhenoGen
PROSITE SURP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000000931 RatGTEx
  ENSRNOG00055000361 RatGTEx
  ENSRNOG00060011465 RatGTEx
  ENSRNOG00065001420 RatGTEx
SMART DRY_EERY UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SWAP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF109905 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2JZ87 ENTREZGENE, UniProtKB/TrEMBL
  A0A1W2Q681 ENTREZGENE, UniProtKB/TrEMBL
  A6J0R5 ENTREZGENE, UniProtKB/TrEMBL
  D3ZTQ1 ENTREZGENE
  Q3KR71 ENTREZGENE, UniProtKB/TrEMBL
  Q5BJQ4 ENTREZGENE
  SFSWA_RAT UniProtKB/Swiss-Prot
UniProt Secondary Q5BJQ4 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-09-28 Sfswap  splicing factor SWAP  Sfswap  splicing factor SWAP homolog  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2016-05-11 Sfswap  splicing factor SWAP homolog  Sfswap  splicing factor, suppressor of white-apricot homolog  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2016-03-16 Sfswap  splicing factor, suppressor of white-apricot homolog  Sfswap  splicing factor, suppressor of white-apricot family  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2014-04-23 Sfswap  splicing factor, suppressor of white-apricot family  Sfswap  splicing factor, suppressor of white-apricot homolog (Drosophila)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2011-08-01 Sfswap  splicing factor, suppressor of white-apricot homolog (Drosophila)  Sfrs8  splicing factor, arginine/serine-rich 8 (suppressor-of-white-apricot homolog, Drosophila)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2011-07-22 Sfrs8  splicing factor, arginine/serine-rich 8 (suppressor-of-white-apricot homolog, Drosophila)  Srsf8  serine/arginine-rich splicing factor 8   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2011-07-13 Srsf8  serine/arginine-rich splicing factor 8   Sfrs8  splicing factor, arginine/serine-rich 8  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-07 Sfrs8  splicing factor, arginine/serine-rich 8  Sfrs8  splicing factor, arginine/serine-rich 8 (suppressor-of-white-apricot homolog, Drosophila)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Sfrs8  splicing factor, arginine/serine-rich 8 (suppressor-of-white-apricot homolog, Drosophila)  Sfrs8_predicted  splicing factor, arginine/serine-rich 8 (suppressor-of-white-apricot homolog, Drosophila) (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Sfrs8_predicted  splicing factor, arginine/serine-rich 8 (suppressor-of-white-apricot homolog, Drosophila) (predicted)      Symbol and Name status set to approved 70820 APPROVED